Collection of regulogs for GntR/Others transcription factor family

GntR family of transcription factors has numerous representatives both in bacterial and archaeal genomes. The GntR family regulators control various biological processes, including antibiotic production, sensing of nutritional status, growth, proliferation, development, diverse metabolic processes (fatty acid metabolism, amino acid metabolism, acetoin utilization etc) [20047956, 17981966]. Regulators of this family possess a conserved N-terminal HTH DNA binding domain (PF00392). C-terminal domains (responsible for effector-binding and oligomerization) are diverse and heterogeneous within the GntR family and were used to define the FadR, HutC, MocR, and YtrA subfamilies [11756427]. more

The FadR and HutC subfamilies comprise the majority of GntR-family regulators. The MocR subfamily is characterized by a C-terminal domain that is homologous to the class I aminotransferase. Reconstructed regulons from the MocR subfamily were moved to the MocR_GntR family collection.