Regulog HutC - Rhizobiales
| Regulator type: | Transcription factor |
| Regulator family: | GntR/Others |
| Regulation mode: | repressor |
| Biological process: | Histidine utilization |
| Effector: | cis-Urocanic acid |
| Phylum: | Proteobacteria/alpha |
| Visualization: | |
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Allows to visualize regulog content in the context of metabolic pathways |
Member of regulog collections
- By taxonomy - Rhizobiales
- By trascription factor - HutC
- By TF family - GntR/Others
- By effector - cis-Urocanic acid
- By pathway - Histidine utilization
| Genome | Genes | Operons |
|---|---|---|
| Sinorhizobium meliloti 1021 | 18 | 5 |
| Rhizobium sp. NGR234 | 11 | 3 |
| Rhizobium leguminosarum bv. viciae 3841 | 12 | 4 |
| Rhizobium etli CFN 42 | 7 | 2 |
| Agrobacterium tumefaciens str. C58 (Cereon) | 17 | 5 |
| Mesorhizobium sp. BNC1 | 8 | 3 |
| Mesorhizobium loti MAFF303099 | 13 | 5 |
| Brucella melitensis 16M | 7 | 2 |
| Bartonella quintana str. Toulouse | ||
| Rhodopseudomonas palustris CGA009 | ||
| Bradyrhizobium japonicum USDA 110 | 8 | 2 |
| Bradyrhizobium sp. BTAi1 | 8 | 2 |
| Nitrobacter winogradskyi Nb-255 | ||
| Azorhizobium caulinodans ORS 571 | ||
| Xanthobacter autotrophicus Py2 |
| Genes | Function | |||||||||||||||
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| CRON 1. | ||||||||||||||||
| COG3842 (PotA) |
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Sinorhizobium meliloti 1021 Site: position = -110 score = 5.43697 sequence = AATATGTATAGACAACTA Gene: SMa0391: ABC transporter, ATPase component |
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Gene: Xaut_2580: ABC transporter, ATPase component |
ABC transporter, ATPase component |
| COG687 (PotD) |
Gene: SMa0392: ABC transporter, periplasmic binding protein |
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Gene: Xaut_2577: ABC transporter, periplasmic binding protein |
ABC transporter, periplasmic binding protein |
| COG1176 (PotB) |
Gene: SMa0394: ABC transporter, permease component |
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Gene: Xaut_2578: ABC transporter, permease component |
ABC transporter, permease component |
| COG1177 (PotC) |
Gene: SMa0396: ABC transporter, permease component |
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Gene: Xaut_2579: ABC transporter, permease component |
ABC transporter, permease component |
| hisD |
Gene: SMa0398: Histidinol dehydrogenase (EC 1.1.1.23) |
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Gene: mlr7107: Histidinol dehydrogenase (EC 1.1.1.23) |
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Histidinol dehydrogenase (EC 1.1.1.23) |
| COG1063 (Tdh) |
Gene: SMa0400: Zn-dependent dehydrogenase |
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Gene: mlr7108: Zn-dependent dehydrogenase |
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Zn-dependent dehydrogenase |
| hutC |
*3
Sinorhizobium meliloti 1021 Gene: SMa0402: Histidine utilization repressor, GntR family Site: position = -110 score = 4.40713 sequence = TGGTTGTATATGGAACTA Gene: SMc00674: Histidine utilization repressor, GntR family Gene: SMa2227: Histidine utilization repressor, GntR family |
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Rhizobium sp. NGR234 Site: position = 1 score = 4.40713 sequence = TGGTTGTATATGGAACTA Gene: NGR_c27380: Histidine utilization repressor, GntR family |
Gene: pRL110210: Histidine utilization repressor, GntR family |
Gene: RHE_PE00076: Histidine utilization repressor, GntR family |
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Agrobacterium tumefaciens str. C58 (Cereon) Site: position = -136 score = 4.16832 sequence = AAGTTCACTATACAACTT Gene: Atu3799: Histidine utilization repressor, GntR family |
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Gene: mlr7110: Histidine utilization repressor, GntR family |
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Histidine utilization repressor, GntR family |
| SMa0403 |
Gene: SMa0403: hypothetical protein |
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Mesorhizobium loti MAFF303099 Site: position = -71 score = 4.698 sequence = CAGATGTATGTACATGTA Gene: mlr7111: hypothetical protein |
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hypothetical protein |
| COG1028 (FabG) |
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Sinorhizobium meliloti 1021 Site: position = -77 score = 4.08133 sequence = ATGATCTGTATATATGTA Site: position = -67 score = 5.61397 sequence = TATATGTATAGACATGTT Site: position = -75 score = 3.87745 sequence = GATCTGTATATATGTATA Gene: SMa0389: Short-chain alcohol dehydrogenase |
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Gene: Meso_2654: Short-chain alcohol dehydrogenase |
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Mesorhizobium loti MAFF303099 Site: position = -72 score = 4.24839 sequence = TGCTTGTATATGTAACTT Site: position = -76 score = 3.75314 sequence = TATATGCTTGTATATGTA Site: position = -82 score = 4.09848 sequence = CGTTTGTATATGCTTGTA Gene: mlr7106: Short-chain alcohol dehydrogenase |
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Short-chain alcohol dehydrogenase |
| CRON 2. | ||||||||||||||||
| hisC |
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Sinorhizobium meliloti 1021 Site: position = -71 score = 4.08133 sequence = TACATATATACAGATCAT Site: position = -73 score = 3.87745 sequence = TATACATATATACAGATC Site: position = -81 score = 5.61397 sequence = AACATGTCTATACATATA Gene: SMa0387: Histidinol-phosphate aminotransferase |
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Mesorhizobium loti MAFF303099 Site: position = -173 score = 4.24839 sequence = AAGTTACATATACAAGCA Site: position = -169 score = 3.75314 sequence = TACATATACAAGCATATA Site: position = -163 score = 4.09848 sequence = TACAAGCATATACAAACG Gene: mll7105: Histidinol-phosphate aminotransferase |
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Gene: RPA4450: Histidinol-phosphate aminotransferase |
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Histidinol-phosphate aminotransferase |
| CRON 3. | ||||||||||||||||
| COG834 (HisJ) |
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Rhizobium leguminosarum bv. viciae 3841 Site: position = -102 score = 4.31178 sequence = TATTTGTATAGTCAAAAG Gene: pRL100360: ABC amino acid transporter, periplasmic binding protein |
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ABC amino acid transporter, periplasmic binding protein |
| COG4160 (ArtM) |
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Gene: pRL100359: ABC amino acid transporter, permease component |
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ABC amino acid transporter, permease component |
| COG765 (HisM) |
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Gene: pRL100358: ABC amino acid transporter, permease component |
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ABC amino acid transporter, permease component |
| COG1126 (GlnQ) |
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Gene: pRL100357: ABC amino acid transporter, ATPase component |
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ABC amino acid transporter, ATPase component |
| CRON 4. | ||||||||||||||||
| hutF |
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Sinorhizobium meliloti 1021 Site: position = -36 score = 4.40713 sequence = TAGTTCCATATACAACCA Gene: SMc00673: Formiminoglutamic iminohydrolase (EC 3.5.3.13) |
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Rhizobium sp. NGR234 Site: position = -34 score = 4.40713 sequence = TAGTTCCATATACAACCA Gene: NGR_c27390: Formiminoglutamic iminohydrolase (EC 3.5.3.13) |
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Rhizobium leguminosarum bv. viciae 3841 Site: position = -96 score = 5.64398 sequence = AACATGTATATACATAAT Site: position = -106 score = 3.60879 sequence = CTTATGCCAAAACATGTA Gene: pRL110207: Formiminoglutamic iminohydrolase (EC 3.5.3.13) |
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Rhizobium etli CFN 42 Site: position = -96 score = 5.64398 sequence = AACATGTATATACATAAT Gene: RHE_PE00074: Formiminoglutamic iminohydrolase (EC 3.5.3.13) |
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Agrobacterium tumefaciens str. C58 (Cereon) Site: position = -88 score = 5.36629 sequence = TAAATGTATATACATAAT Gene: Atu3935: Formiminoglutamic iminohydrolase (EC 3.5.3.13) |
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Mesorhizobium sp. BNC1 Site: position = -84 score = 5.64398 sequence = TACATGTATATACATAAT Gene: Meso_2987: Formiminoglutamic iminohydrolase (EC 3.5.3.13) |
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Mesorhizobium loti MAFF303099 Site: position = -71 score = 5.77876 sequence = ATTATGTATATACATATT Gene: mll8318: Formiminoglutamic iminohydrolase (EC 3.5.3.13) |
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Brucella melitensis 16M Site: position = -101 score = 5.36629 sequence = ATAATGTATATACATATT Gene: BMEII0369: Formiminoglutamic iminohydrolase (EC 3.5.3.13) |
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Bradyrhizobium japonicum USDA 110 Site: position = -53 score = 5.57175 sequence = TATATGTCTAGACATATA Gene: blr6244: Formiminoglutamic iminohydrolase (EC 3.5.3.13) |
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Bradyrhizobium sp. BTAi1 Site: position = -54 score = 5.60176 sequence = AATATGTCTATACATAAA Gene: BBta_6453: Formiminoglutamic iminohydrolase (EC 3.5.3.13) |
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Formiminoglutamic iminohydrolase (EC 3.5.3.13) |
| hutX |
Gene: SMc00672: Histidine ABC transporter, histidine-binding protein (TC 3.A.1) |
Gene: NGR_c27400: Histidine ABC transporter, histidine-binding protein (TC 3.A.1) |
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Agrobacterium tumefaciens str. C58 (Cereon) Site: position = -165 score = 4.16832 sequence = AAGTTGTATAGTGAACTT Gene: Atu3800: Histidine ABC transporter, histidine-binding protein (TC 3.A.1) |
Gene: Meso_2543: Histidine ABC transporter, histidine-binding protein (TC 3.A.1) |
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Histidine ABC transporter, histidine-binding protein (TC 3.A.1) |
| hutW |
Gene: SMc00671: Histidine ABC transporter, permease protein (TC 3.A.1) |
Gene: NGR_c27410: Histidine ABC transporter, permease protein (TC 3.A.1) |
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Gene: Atu3801: Histidine ABC transporter, permease protein (TC 3.A.1) |
Gene: Meso_2542: Histidine ABC transporter, permease protein (TC 3.A.1) |
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Histidine ABC transporter, permease protein (TC 3.A.1) |
| hutV |
Gene: SMc00670: Histidine ABC transporter, ATP-binding protein (TC 3.A.1) |
Gene: NGR_c27420: Histidine ABC transporter, ATP-binding protein (TC 3.A.1) |
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Gene: Atu3802: Histidine ABC transporter, ATP-binding protein (TC 3.A.1) |
Gene: Meso_2541: Histidine ABC transporter, ATP-binding protein (TC 3.A.1) |
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Histidine ABC transporter, ATP-binding protein (TC 3.A.1) |
| hutH2 |
Gene: SMc00669: Histidine ammonia-lyase (EC 4.3.1.3) |
Gene: NGR_c27430: Histidine ammonia-lyase (EC 4.3.1.3) |
Gene: pRL110215: Histidine ammonia-lyase (EC 4.3.1.3) |
Gene: RHE_PE00081: Histidine ammonia-lyase (EC 4.3.1.3) |
Gene: Atu3803: Histidine ammonia-lyase (EC 4.3.1.3) |
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Gene: mll0151: Histidine ammonia-lyase (EC 4.3.1.3) |
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Histidine ammonia-lyase (EC 4.3.1.3) |
| COG3314 |
Gene: SMc00668: Predicted histidine uptake transporter |
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Predicted histidine uptake transporter |
| hutD |
Gene: SMc00667: Conserved hypothetical protein related to histidine degradation |
Gene: NGR_c27440: Conserved hypothetical protein related to histidine degradation |
Gene: pRL110202: Conserved hypothetical protein related to histidine degradation |
Gene: RHE_PE00069: Conserved hypothetical protein related to histidine degradation |
Gene: Atu3929: Conserved hypothetical protein related to histidine degradation |
Gene: Meso_2982: Conserved hypothetical protein related to histidine degradation |
Gene: mlr8324: Conserved hypothetical protein related to histidine degradation |
Gene: BMEII0364: Conserved hypothetical protein related to histidine degradation |
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Conserved hypothetical protein related to histidine degradation |
| hutI |
Gene: SM_b21166: Imidazolonepropionase (EC 3.5.2.7) |
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Rhizobium sp. NGR234 Site: position = -42 score = 5.21931 sequence = ATTATGTATATACATTAT Gene: NGR_b13270: Imidazolonepropionase (EC 3.5.2.7) |
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Rhizobium leguminosarum bv. viciae 3841 Site: position = -44 score = 5.64398 sequence = ATTATGTATATACATGTT Gene: pRL110206: Imidazolonepropionase (EC 3.5.2.7) |
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Rhizobium etli CFN 42 Site: position = -44 score = 5.64398 sequence = ATTATGTATATACATGTT Gene: RHE_PE00073: Imidazolonepropionase (EC 3.5.2.7) |
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Agrobacterium tumefaciens str. C58 (Cereon) Site: position = -43 score = 5.36629 sequence = ATTATGTATATACATTTA Gene: Atu3934: Imidazolonepropionase (EC 3.5.2.7) |
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Mesorhizobium sp. BNC1 Site: position = -45 score = 5.64398 sequence = ATTATGTATATACATGTA Gene: Meso_2986: Imidazolonepropionase (EC 3.5.2.7) |
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Mesorhizobium loti MAFF303099 Site: position = -44 score = 5.77876 sequence = AATATGTATATACATAAT Gene: mlr8319: Imidazolonepropionase (EC 3.5.2.7) Gene: mlr9376: Imidazolonepropionase (EC 3.5.2.7) |
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Brucella melitensis 16M Site: position = -47 score = 5.36629 sequence = AATATGTATATACATTAT Gene: BMEII0368: Imidazolonepropionase (EC 3.5.2.7) |
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Bradyrhizobium japonicum USDA 110 Gene: blr0249: Imidazolonepropionase (EC 3.5.2.7) Site: position = -64 score = 5.57175 sequence = TATATGTCTAGACATATA Gene: bll6243: Imidazolonepropionase (EC 3.5.2.7) |
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Bradyrhizobium sp. BTAi1 Site: position = -53 score = 5.60176 sequence = TTTATGTATAGACATATT Gene: BBta_6452: Imidazolonepropionase (EC 3.5.2.7) |
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Imidazolonepropionase (EC 3.5.2.7) |
| hutH |
Gene: SMb21165: Histidine ammonia-lyase (EC 4.3.1.3) |
Gene: NGR_b13260: Histidine ammonia-lyase (EC 4.3.1.3) |
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Rhizobium leguminosarum bv. viciae 3841 Gene: pRL110205: Histidine ammonia-lyase (EC 4.3.1.3) Gene: RL4470: Histidine ammonia-lyase (EC 4.3.1.3) |
Gene: RHE_PE00072: Histidine ammonia-lyase (EC 4.3.1.3) |
Gene: Atu3933: Histidine ammonia-lyase (EC 4.3.1.3) |
Gene: Meso_2985: Histidine ammonia-lyase (EC 4.3.1.3) |
Gene: mlr8321: Histidine ammonia-lyase (EC 4.3.1.3) |
Gene: BMEII0367: Histidine ammonia-lyase (EC 4.3.1.3) |
Gene: BQ06730: Histidine ammonia-lyase (EC 4.3.1.3) |
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Gene: bll6242: Histidine ammonia-lyase (EC 4.3.1.3) |
Gene: BBta_6451: Histidine ammonia-lyase (EC 4.3.1.3) |
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Histidine ammonia-lyase (EC 4.3.1.3) |
| hutG |
Gene: SMb21164: N-formylglutamate deformylase (EC 3.5.1.68) |
Gene: NGR_b13250: N-formylglutamate deformylase (EC 3.5.1.68) |
Gene: pRL110204: N-formylglutamate deformylase (EC 3.5.1.68) |
Gene: RHE_PE00071: N-formylglutamate deformylase (EC 3.5.1.68) |
Gene: Atu3932: N-formylglutamate deformylase (EC 3.5.1.68) |
Gene: Meso_2984: N-formylglutamate deformylase (EC 3.5.1.68) |
Gene: mlr8322: N-formylglutamate deformylase (EC 3.5.1.68) |
Gene: BMEII0366: N-formylglutamate deformylase (EC 3.5.1.68) |
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N-formylglutamate deformylase (EC 3.5.1.68) |
| hutU |
Gene: SMb21163: Urocanate hydratase (EC 4.2.1.49) |
Gene: NGR_b13240: Urocanate hydratase (EC 4.2.1.49) |
Gene: pRL110203: Urocanate hydratase (EC 4.2.1.49) |
Gene: RHE_PE00070: Urocanate hydratase (EC 4.2.1.49) |
Gene: Atu3931: Urocanate hydratase (EC 4.2.1.49) |
Gene: Meso_2983: Urocanate hydratase (EC 4.2.1.49) |
Gene: mlr8323: Urocanate hydratase (EC 4.2.1.49) |
Gene: BMEII0365: Urocanate hydratase (EC 4.2.1.49) |
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Gene: bll6241: Urocanate hydratase (EC 4.2.1.49) |
Gene: BBta_6450: Urocanate hydratase (EC 4.2.1.49) |
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Urocanate hydratase (EC 4.2.1.49) |
| COG596 (MhpC) |
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Gene: NGR_c28340: Putative hydrolases or acyltransferases (alpha/beta hydrolase superfamily) |
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Gene: RHE_CH03535: Putative hydrolases or acyltransferases (alpha/beta hydrolase superfamily) |
Gene: Atu3930: Putative hydrolases or acyltransferases (alpha/beta hydrolase superfamily) |
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Gene: mlr3816: Putative hydrolases or acyltransferases (alpha/beta hydrolase superfamily) |
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Putative hydrolases or acyltransferases (alpha/beta hydrolase superfamily) |
| hutC |
Gene: SMb20048: Histidine utilization repressor, GntR family |
Gene: NGR_b23610: Histidine utilization repressor, GntR family |
Gene: pRL110208: Histidine utilization repressor, GntR family |
Gene: RHE_PE00075: Histidine utilization repressor, GntR family |
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Agrobacterium tumefaciens str. C58 (Cereon) Gene: Atu3936: Histidine utilization repressor, GntR family Gene: Atu0160: Histidine utilization repressor, GntR family |
Gene: Meso_2988: Histidine utilization repressor, GntR family |
Gene: mll8317: Histidine utilization repressor, GntR family |
Gene: BMEII0370: Histidine utilization repressor, GntR family |
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Gene: blr6245: Histidine utilization repressor, GntR family |
Gene: BBta_6454: Histidine utilization repressor, GntR family |
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Histidine utilization repressor, GntR family |
| hisX |
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Agrobacterium tumefaciens str. C58 (Cereon) Site: position = -35 score = 4.7539 sequence = ATTTTGTCTAGACAAATG Gene: Atu0157: Putative histidine ABC transporter, substrate binding protein |
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Gene: mll1256: Putative histidine ABC transporter, substrate binding protein |
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Gene: blr6246: Putative histidine ABC transporter, substrate binding protein |
Gene: BBta_6455: Putative histidine ABC transporter, substrate binding protein |
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Putative histidine ABC transporter, substrate binding protein |
| hisY |
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Gene: Atu0158: Putative histidine ABC transporter, permease protein |
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Gene: mll1254: Putative histidine ABC transporter, permease protein |
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Gene: blr6247: Putative histidine ABC transporter, permease protein |
Gene: BBta_6456: Putative histidine ABC transporter, permease protein |
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Putative histidine ABC transporter, permease protein |
| hisZ |
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Gene: Atu0159: Putative histidine ABC transporter, ATPase protein |
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Gene: mll1253: Putative histidine ABC transporter, ATPase protein |
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Gene: blr6248: Putative histidine ABC transporter, ATPase protein |
Gene: BBta_6457: Putative histidine ABC transporter, ATPase protein |
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Putative histidine ABC transporter, ATPase protein |
| CRON 5. | ||||||||||||||||
| hutC |
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Mesorhizobium sp. BNC1 Site: position = -169 score = 4.78347 sequence = AATTAGTATAGACATAAT Gene: Meso_2976: Histidine utilization repressor, GntR family |
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Histidine utilization repressor, GntR family |
| CRON 6. | ||||||||||||||||
| hutC |
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Rhizobium leguminosarum bv. viciae 3841 Site: position = -143 score = 4.31178 sequence = CTTTTGACTATACAAATA Gene: pRL100361: Histidine utilization repressor, GntR family |
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Histidine utilization repressor, GntR family |
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
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Regulatory Sites | [ FASTA format ] | DOWNLOAD |