Regulog GguR - Burkholderia

Properties
Regulator type:	Transcription factor
Regulator family:	GntR/Others
Regulation mode:
Biological process:	Glucarate utilization; Galactarate utilization
Effector:
Phylum:	Proteobacteria/Beta
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 67 sites [see more]

Member of regulog collections

By taxonomy - Burkholderia
By trascription factor - GguR
By TF family - GntR/Others
By pathway - Glucarate utilization
By pathway - Galactarate utilization

Statistics of regulated genes
Genome	Genes	Operons
Burkholderia pseudomallei K96243
Burkholderia mallei ATCC 23344
Burkholderia sp. 383	14	9
Burkholderia cepacia AMMD	17	10
Burkholderia vietnamiensis G4	12	10
Burkholderia glumae BGR1	16	10
Burkholderia xenovorans LB400	12	6
Burkholderia phymatum STM815	9	5

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes									Function

CRON 1.
uxuP	Burkholderia pseudomallei K96243	Burkholderia mallei ATCC 23344	* Burkholderia sp. 383 Site: position = -347 score = 4.83203 sequence = CAGTCATCCTATGACAA Gene: Bcep18194_C7436: Predicted glucuronate /galacturonate TRAP-type transporter, periplasmic component	* Burkholderia cepacia AMMD Site: position = -341 score = 4.71251 sequence = CAGTCATCCTATGACGA Gene: Bamb_6123: Predicted glucuronate /galacturonate TRAP-type transporter, periplasmic component	* Burkholderia vietnamiensis G4 Site: position = -329 score = 4.85371 sequence = CAGTCATCGGACAACTA Gene: Bcep1808_6572: Predicted glucuronate /galacturonate TRAP-type transporter, periplasmic component	* Burkholderia glumae BGR1 Site: position = -497 score = 4.89854 sequence = CAGTCGTCTTATAACAT Gene: bglu_2g13770: Predicted glucuronate /galacturonate TRAP-type transporter, periplasmic component	* Burkholderia xenovorans LB400 Site: position = -322 score = 5.24413 sequence = ATGTCGTCGTACAACAT Gene: Bxe_B1798: Predicted glucuronate /galacturonate TRAP-type transporter, periplasmic component	Burkholderia phymatum STM815	Predicted glucuronate /galacturonate TRAP-type transporter, periplasmic component
uxuQ	Burkholderia pseudomallei K96243	Burkholderia mallei ATCC 23344	Burkholderia sp. 383 Gene: Bcep18194_C7435: Predicted glucuronate /galacturonate TRAP-type transporter, small permease component	Burkholderia cepacia AMMD Gene: Bamb_6124: Predicted glucuronate /galacturonate TRAP-type transporter, small permease component	Burkholderia vietnamiensis G4 Gene: Bcep1808_6571: Predicted glucuronate /galacturonate TRAP-type transporter, small permease component	Burkholderia glumae BGR1 Gene: bglu_2g13760: Predicted glucuronate /galacturonate TRAP-type transporter, small permease component	Burkholderia xenovorans LB400 Gene: Bxe_B1797: Predicted glucuronate /galacturonate TRAP-type transporter, small permease component	Burkholderia phymatum STM815	Predicted glucuronate /galacturonate TRAP-type transporter, small permease component
uxuM	Burkholderia pseudomallei K96243	Burkholderia mallei ATCC 23344	Burkholderia sp. 383 Gene: Bcep18194_C7434: Predicted glucuronate /galacturonate TRAP-type transporter, large permease component	Burkholderia cepacia AMMD Gene: Bamb_6125: Predicted glucuronate /galacturonate TRAP-type transporter, large permease component	Burkholderia vietnamiensis G4 Gene: Bcep1808_6570: Predicted glucuronate /galacturonate TRAP-type transporter, large permease component	Burkholderia glumae BGR1 Gene: bglu_2g13750: Predicted glucuronate /galacturonate TRAP-type transporter, large permease component	Burkholderia xenovorans LB400 Gene: Bxe_B1796: Predicted glucuronate /galacturonate TRAP-type transporter, large permease component	Burkholderia phymatum STM815	Predicted glucuronate /galacturonate TRAP-type transporter, large permease component
uxuF2	Burkholderia pseudomallei K96243	Burkholderia mallei ATCC 23344	Burkholderia sp. 383	Burkholderia cepacia AMMD Gene: Bamb_6126: Predicted uronate lactonase, PF10282 family	Burkholderia vietnamiensis G4	Burkholderia glumae BGR1	Burkholderia xenovorans LB400	Burkholderia phymatum STM815	Predicted uronate lactonase, PF10282 family
mcp	Burkholderia pseudomallei K96243	Burkholderia mallei ATCC 23344	Burkholderia sp. 383	Burkholderia cepacia AMMD Gene: Bamb_6127: methyl-accepting chemotaxis sensory transducer	* Burkholderia vietnamiensis G4 Site: position = -303 score = 4.83363 sequence = ATGTTATACGATGACAC Gene: Bcep1808_4374: methyl-accepting chemotaxis sensory transducer	Burkholderia glumae BGR1	Burkholderia xenovorans LB400	Burkholderia phymatum STM815 Gene: Bphy_5591: methyl-accepting chemotaxis sensory transducer	methyl-accepting chemotaxis sensory transducer
omp	Burkholderia pseudomallei K96243	Burkholderia mallei ATCC 23344	Burkholderia sp. 383	Burkholderia cepacia AMMD	Burkholderia vietnamiensis G4	Burkholderia glumae BGR1	Burkholderia xenovorans LB400 Gene: Bxe_B1795: Outer membrane protein (porin)	Burkholderia phymatum STM815	Outer membrane protein (porin)

CRON 2.
garL	Burkholderia pseudomallei K96243	Burkholderia mallei ATCC 23344	Burkholderia sp. 383	Burkholderia cepacia AMMD	Burkholderia vietnamiensis G4	Burkholderia glumae BGR1	Burkholderia xenovorans LB400	* Burkholderia phymatum STM815 Site: position = -77 score = 4.52301 sequence = CAGACATCCTATGACAT Site: position = -200 score = 4.50213 sequence = CGGTCATCGTACAACAA Gene: Bphy_6527: 2-dehydro-3-deoxyglucarate aldolase (EC 4.1.2.20)	2-dehydro-3-deoxyglucarate aldolase (EC 4.1.2.20)
garR	Burkholderia pseudomallei K96243	Burkholderia mallei ATCC 23344	Burkholderia sp. 383	Burkholderia cepacia AMMD	Burkholderia vietnamiensis G4	Burkholderia glumae BGR1	Burkholderia xenovorans LB400	Burkholderia phymatum STM815 Gene: Bphy_6528: 2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60)	2-hydroxy-3-oxopropionate reductase (EC 1.1.1.60)
uxuF	Burkholderia pseudomallei K96243	Burkholderia mallei ATCC 23344	Burkholderia sp. 383 Gene: Bcep18194_A5499: Predicted uronate lactonase, PF10282 family	Burkholderia cepacia AMMD Gene: Bamb_2221: Predicted uronate lactonase, PF10282 family	* Burkholderia vietnamiensis G4 Site: position = -239 score = 5.27833 sequence = ATGTCATACGACGACAT Gene: Bcep1808_2255: Predicted uronate lactonase, PF10282 family	* Burkholderia glumae BGR1 Site: position = -114 score = 4.86792 sequence = AAGTTATATGATGACGT Gene: bglu_2g05570: Predicted uronate lactonase, PF10282 family	Burkholderia xenovorans LB400	Burkholderia phymatum STM815 Gene: Bphy_6529: Predicted uronate lactonase, PF10282 family	Predicted uronate lactonase, PF10282 family
gudD	Burkholderia pseudomallei K96243	Burkholderia mallei ATCC 23344	* Burkholderia sp. 383 Site: position = -268 score = 5.16604 sequence = AAGTCATCCGACGACTG Gene: Bcep18194_A4275: Glucarate dehydratase (EC 4.2.1.40)	* Burkholderia cepacia AMMD Site: position = -270 score = 5.16604 sequence = AAGTCATCCGACGACTG Gene: Bamb_1041: Glucarate dehydratase (EC 4.2.1.40)	* Burkholderia vietnamiensis G4 Site: position = -333 score = 5.16604 sequence = AAGTCATCCGACGACTG Gene: Bcep1808_1081: Glucarate dehydratase (EC 4.2.1.40)	* Burkholderia glumae BGR1 Site: position = -207 score = 5.02574 sequence = ATGTCATCAGACAACGT Gene: bglu_2g00180: Glucarate dehydratase (EC 4.2.1.40)	* Burkholderia xenovorans LB400 Site: position = -106 score = 5.04202 sequence = CTGTCATCGTACAACAT Gene: Bxe_B0539: Glucarate dehydratase (EC 4.2.1.40)	Burkholderia phymatum STM815 Gene: Bphy_6530: Glucarate dehydratase (EC 4.2.1.40)	Glucarate dehydratase (EC 4.2.1.40)
kdgD	Burkholderia pseudomallei K96243	Burkholderia mallei ATCC 23344	* Burkholderia sp. 383 Site: position = -198 score = 4.91333 sequence = TAGTCATCATACGACAT Site: position = -92 score = 4.84648 sequence = TCGTTGTACGATGACAT Gene: Bcep18194_B0332: 5-dehydro-4-deoxyglucarate dehydratase (EC 4.2.1.41)	* Burkholderia cepacia AMMD Site: position = -207 score = 4.91333 sequence = TAGTCATCATACGACAT Site: position = -102 score = 4.84648 sequence = TCGTTGTACGATGACAT Gene: Bamb_4676: 5-dehydro-4-deoxyglucarate dehydratase (EC 4.2.1.41)	* Burkholderia vietnamiensis G4 Site: position = -198 score = 4.91333 sequence = TAGTCATCATACGACAT Site: position = -92 score = 4.77071 sequence = GCGTTGTACGATGACAT Gene: Bcep1808_3561: 5-dehydro-4-deoxyglucarate dehydratase (EC 4.2.1.41)	2 Burkholderia glumae BGR1* Site: position = -186 score = 4.89854 sequence = CAGTCATCATACAACAT Site: position = -75 score = 5.18752 sequence = ATGTTGTACGATGACAT Gene: bglu_2g03730: 5-dehydro-4-deoxyglucarate dehydratase (EC 4.2.1.41) Gene: bglu_2g00190: 5-dehydro-4-deoxyglucarate dehydratase (EC 4.2.1.41)	* Burkholderia xenovorans LB400 Site: position = -83 score = 4.84648 sequence = TTGTTGTACGATGACGT Site: position = -178 score = 5.068 sequence = ACGTCATCCTACAACAT Gene: Bxe_B1802: 5-dehydro-4-deoxyglucarate dehydratase (EC 4.2.1.41)	Burkholderia phymatum STM815 Gene: Bphy_6531: 5-dehydro-4-deoxyglucarate dehydratase (EC 4.2.1.41)	5-dehydro-4-deoxyglucarate dehydratase (EC 4.2.1.41)
gudP	Burkholderia pseudomallei K96243	Burkholderia mallei ATCC 23344	* Burkholderia sp. 383 Site: position = -25 score = 5.03929 sequence = ACGTCATACGACGACGT Gene: Bcep18194_B0327: D-glucarate permease	* Burkholderia cepacia AMMD Site: position = -140 score = 4.14412 sequence = ATGTCTGCCGACGACAT Gene: Bamb_4680: D-glucarate permease	* Burkholderia vietnamiensis G4 Site: position = -26 score = 5.15881 sequence = ATGTCATACGACGACGT Gene: Bcep1808_3563: D-glucarate permease	* Burkholderia glumae BGR1 Site: position = -69 score = 5.22146 sequence = AAGTTGTACGACGACAT Gene: bglu_2g03700: D-glucarate permease	Burkholderia xenovorans LB400 Gene: Bxe_B1803: D-glucarate permease	Burkholderia phymatum STM815	D-glucarate permease
gguT	Burkholderia pseudomallei K96243	Burkholderia mallei ATCC 23344	* Burkholderia sp. 383 Site: position = -89 score = 5.27833 sequence = ATGTCATACGACGACAT Gene: Bcep18194_A5498: Predicted hexarate transporter	* Burkholderia cepacia AMMD Site: position = -86 score = 5.27833 sequence = ATGTCATACGACGACAT Gene: Bamb_2220: Predicted hexarate transporter	Burkholderia vietnamiensis G4	Burkholderia glumae BGR1	Burkholderia xenovorans LB400	Burkholderia phymatum STM815	Predicted hexarate transporter

CRON 3.
kgsD	Burkholderia pseudomallei K96243	Burkholderia mallei ATCC 23344	* Burkholderia sp. 383 Site: position = -239 score = 5.03929 sequence = ACGTCGTCGTATGACGT Gene: Bcep18194_B0328: Alpha-ketoglutaric semialdehyde dehydrogenase (EC 1.2.1.26)	* Burkholderia cepacia AMMD Site: position = -240 score = 5.15881 sequence = ACGTCGTCGTATGACAT Site: position = -71 score = 4.14412 sequence = ATGTCGTCGGCAGACAT Gene: Bamb_4679: Alpha-ketoglutaric semialdehyde dehydrogenase (EC 1.2.1.26)	* Burkholderia vietnamiensis G4 Site: position = -241 score = 5.15881 sequence = ACGTCGTCGTATGACAT Gene: Bcep1808_3562: Alpha-ketoglutaric semialdehyde dehydrogenase (EC 1.2.1.26)	* Burkholderia glumae BGR1 Site: position = -212 score = 5.22146 sequence = ATGTCGTCGTACAACTT Gene: bglu_2g03710: Alpha-ketoglutaric semialdehyde dehydrogenase (EC 1.2.1.26)	* Burkholderia xenovorans LB400 Site: position = -48 score = 4.86915 sequence = ATGTTGTAGGATGACCT Site: position = -160 score = 4.39013 sequence = AAGTCGTCGTATATCTA Gene: Bxe_B1805: Alpha-ketoglutaric semialdehyde dehydrogenase (EC 1.2.1.26)	* Burkholderia phymatum STM815 Site: position = -48 score = 4.50213 sequence = TTGTTGTACGATGACCG Site: position = -171 score = 4.52301 sequence = ATGTCATAGGATGTCTG Gene: Bphy_6526: Alpha-ketoglutaric semialdehyde dehydrogenase (EC 1.2.1.26)	Alpha-ketoglutaric semialdehyde dehydrogenase (EC 1.2.1.26)

CRON 4.
garP	Burkholderia pseudomallei K96243	Burkholderia mallei ATCC 23344	Burkholderia sp. 383	Burkholderia cepacia AMMD	Burkholderia vietnamiensis G4	Burkholderia glumae BGR1	Burkholderia xenovorans LB400	* Burkholderia phymatum STM815 Site: position = -92 score = 4.8835 sequence = ATGTCGTCAGACAACCT Site: position = -223 score = 4.95643 sequence = ACGTCGTCGTACAACTG Gene: Bphy_6596: D-galactarate permease	D-galactarate permease

CRON 5.
pgl	Burkholderia pseudomallei K96243	Burkholderia mallei ATCC 23344	Burkholderia sp. 383	* Burkholderia cepacia AMMD Site: position = -73 score = 4.61137 sequence = ATGTAGTACGACGACGT Gene: Bamb_4904: Polygalacturonase (EC 3.2.1.15)	* Burkholderia vietnamiensis G4 Site: position = -70 score = 4.64131 sequence = ATGTGATACGACGACGT Gene: Bcep1808_3851: Polygalacturonase (EC 3.2.1.15)	* Burkholderia glumae BGR1 Site: position = -77 score = 5.1022 sequence = ATGTCATCGTATGACGT Gene: bglu_2g07210: Polygalacturonase (EC 3.2.1.15)	Burkholderia xenovorans LB400	Burkholderia phymatum STM815	Polygalacturonase (EC 3.2.1.15)

CRON 6.
exuT	Burkholderia pseudomallei K96243	Burkholderia mallei ATCC 23344	* Burkholderia sp. 383 Site: position = -196 score = 4.97709 sequence = CAGTCGTCAGATAACAT Gene: Bcep18194_B1871: Hexuronate transporter, MFS family	* Burkholderia cepacia AMMD Site: position = -106 score = 4.85757 sequence = CAGTCGTCAGATAACGT Gene: Bamb_3566: Hexuronate transporter, MFS family	Burkholderia vietnamiensis G4	* Burkholderia glumae BGR1 Site: position = -90 score = 4.56998 sequence = AAGTGGTACGATGACTG Site: position = -180 score = 4.49382 sequence = ACGTTGTCTGACGAGAT Gene: bglu_2g04250: Hexuronate transporter, MFS family	Burkholderia xenovorans LB400	Burkholderia phymatum STM815 Gene: Bphy_3128: Hexuronate transporter, MFS family	Hexuronate transporter, MFS family
agl	Burkholderia pseudomallei K96243	Burkholderia mallei ATCC 23344	Burkholderia sp. 383 Gene: Bcep18194_B1872: Alpha-glucosidase (EC 3.2.1.20)	Burkholderia cepacia AMMD Gene: Bamb_3565: Alpha-glucosidase (EC 3.2.1.20)	Burkholderia vietnamiensis G4	Burkholderia glumae BGR1 Gene: bglu_2g04260: Alpha-glucosidase (EC 3.2.1.20)	Burkholderia xenovorans LB400	Burkholderia phymatum STM815 Gene: Bphy_3127: Alpha-glucosidase (EC 3.2.1.20)	Alpha-glucosidase (EC 3.2.1.20)
omp	Burkholderia pseudomallei K96243	Burkholderia mallei ATCC 23344	Burkholderia sp. 383 Gene: Bcep18194_B1873: Outer membrane porin protein 32 precursor	Burkholderia cepacia AMMD Gene: Bamb_3564: Outer membrane porin protein 32 precursor	Burkholderia vietnamiensis G4	Burkholderia glumae BGR1 Gene: bglu_2g04270: Outer membrane porin protein 32 precursor	Burkholderia xenovorans LB400	Burkholderia phymatum STM815 Gene: Bphy_3126: Outer membrane porin protein 32 precursor	Outer membrane porin protein 32 precursor

CRON 7.
garD	Burkholderia pseudomallei K96243	Burkholderia mallei ATCC 23344	* Burkholderia sp. 383 Site: position = -154 score = 4.84648 sequence = ATGTCATCGTACAACGA Site: position = -48 score = 4.91333 sequence = ATGTCGTATGATGACTA Gene: Bcep18194_B0333: D-galactarate dehydratase (EC 4.2.1.42)	* Burkholderia cepacia AMMD Site: position = -48 score = 4.91333 sequence = ATGTCGTATGATGACTA Site: position = -153 score = 4.84648 sequence = ATGTCATCGTACAACGA Gene: Bamb_4675: D-galactarate dehydratase (EC 4.2.1.42)	* Burkholderia vietnamiensis G4 Site: position = -49 score = 4.91333 sequence = ATGTCGTATGATGACTA Site: position = -155 score = 4.77071 sequence = ATGTCATCGTACAACGC Gene: Bcep1808_3560: D-galactarate dehydratase (EC 4.2.1.42)	* Burkholderia glumae BGR1 Site: position = -164 score = 5.18752 sequence = ATGTCATCGTACAACAT Site: position = -53 score = 4.89854 sequence = ATGTTGTATGATGACTG Gene: bglu_2g03740: D-galactarate dehydratase (EC 4.2.1.42)	* Burkholderia xenovorans LB400 Site: position = -159 score = 4.84648 sequence = ACGTCATCGTACAACAA Site: position = -64 score = 5.068 sequence = ATGTTGTAGGATGACGT Gene: Bxe_B1801: D-galactarate dehydratase (EC 4.2.1.42)	* Burkholderia phymatum STM815 Site: position = -67 score = 4.77071 sequence = ATGTTGTACGATGACGC Gene: Bphy_6382: D-galactarate dehydratase (EC 4.2.1.42)	D-galactarate dehydratase (EC 4.2.1.42)
udh	Burkholderia pseudomallei K96243	Burkholderia mallei ATCC 23344	Burkholderia sp. 383 Gene: Bcep18194_B2716: Uronate dehydrogenase (EC 1.1.1.203)	Burkholderia cepacia AMMD Gene: Bamb_5236: Uronate dehydrogenase (EC 1.1.1.203)	Burkholderia vietnamiensis G4 Gene: Bcep1808_3989: Uronate dehydrogenase (EC 1.1.1.203)	* Burkholderia glumae BGR1 Site: position = -94 score = 4.37422 sequence = CAGTCATCGTATAAGAT Gene: bglu_1g09950: Uronate dehydrogenase (EC 1.1.1.203)	Burkholderia xenovorans LB400 Gene: Bxe_B1800: Uronate dehydrogenase (EC 1.1.1.203)	Burkholderia phymatum STM815 Gene: Bphy_5673: Uronate dehydrogenase (EC 1.1.1.203)	Uronate dehydrogenase (EC 1.1.1.203)
uxuL	Burkholderia pseudomallei K96243	Burkholderia mallei ATCC 23344	Burkholderia sp. 383	Burkholderia cepacia AMMD	Burkholderia vietnamiensis G4	Burkholderia glumae BGR1	Burkholderia xenovorans LB400 Gene: Bxe_B1799: Predicted glucuronolactone/galactarolactone lactonase	Burkholderia phymatum STM815	Predicted glucuronolactone/galactarolactone lactonase
gguR	Burkholderia pseudomallei K96243	Burkholderia mallei ATCC 23344	* Burkholderia sp. 383 Site: position = -107 score = 5.16604 sequence = CAGTCGTCGGATGACTT Gene: Bcep18194_A4276: Predicted D-glucarate or D-galactorate utilization regulator, GntR family	* Burkholderia cepacia AMMD Site: position = -107 score = 5.16604 sequence = CAGTCGTCGGATGACTT Gene: Bamb_1043: Predicted D-glucarate or D-galactorate utilization regulator, GntR family	* Burkholderia vietnamiensis G4 Site: position = -107 score = 5.16604 sequence = CAGTCGTCGGATGACTT Gene: Bcep1808_1082: Predicted D-glucarate or D-galactorate utilization regulator, GntR family	* Burkholderia glumae BGR1 Site: position = -99 score = 5.10943 sequence = CAGTCATCGGATGACTT Gene: bglu_1g09940: Predicted D-glucarate or D-galactorate utilization regulator, GntR family	* Burkholderia xenovorans LB400 Site: position = -70 score = 4.80287 sequence = CAGTCATCAGACGACGG Gene: Bxe_B1804: Predicted D-glucarate or D-galactorate utilization regulator, GntR family	* Burkholderia phymatum STM815 Site: position = -51 score = 4.69554 sequence = GCGTTGTCGGACAACGT Gene: Bphy_6525: Predicted D-glucarate or D-galactorate utilization regulator, GntR family	Predicted D-glucarate or D-galactorate utilization regulator, GntR family

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog GguR - Burkholderia

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --