Regulog IolR - Mycobacteriaceae

Properties
Regulator type:	Transcription factor
Regulator family:	GntR/Others
Regulation mode:
Biological process:	Inositol utilization
Effector:
Phylum:	Actinobacteria
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 13 sites [see more]

Member of regulog collections

By taxonomy - Mycobacteriaceae
By TF family - GntR/Others
By pathway - Inositol utilization

Statistics of regulated genes
Genome	Genes	Operons
Mycobacterium abscessus ATCC 19977
Mycobacterium avium 104
Mycobacterium flavescens PYR-GCK	9	3
Mycobacterium leprae TN
Mycobacterium marinum M
Mycobacterium smegmatis str. MC2 155	7	3
Mycobacterium sp. JLS
Mycobacterium tuberculosis H37Rv
Mycobacterium vanbaalenii PYR-1	9	3

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes										Function

CRON 1.
iolC	Mycobacterium abscessus ATCC 19977	Mycobacterium avium 104	* Mycobacterium flavescens PYR-GCK Site: position = -88 score = 5.36767 sequence = AGAATGTCAGGACAAAGT Gene: Mflv_2602: 5-keto-2-deoxygluconokinase (EC 2.7.1.92)	Mycobacterium leprae TN	Mycobacterium marinum M	* Mycobacterium smegmatis str. MC2 155 Site: position = -105 score = 3.71282 sequence = ACAAAGTCTTGACAGACG Site: position = -116 score = 5.08361 sequence = AGAATGTCAGAACAAAGT Gene: MSMEG_4661: 5-keto-2-deoxygluconokinase (EC 2.7.1.92)	Mycobacterium sp. JLS	Mycobacterium tuberculosis H37Rv	* Mycobacterium vanbaalenii PYR-1 Site: position = -80 score = 3.77544 sequence = ACAAAGTCTTGACATGGC Site: position = -91 score = 5.36767 sequence = AGAATGTCAGGACAAAGT Gene: Mvan_4016: 5-keto-2-deoxygluconokinase (EC 2.7.1.92)	5-keto-2-deoxygluconokinase (EC 2.7.1.92)
iolJ	Mycobacterium abscessus ATCC 19977	Mycobacterium avium 104	Mycobacterium flavescens PYR-GCK Gene: Mflv_2601: 5-keto-2-deoxy-D-gluconate-6 phosphate aldolase (EC 4.1.2.29)	Mycobacterium leprae TN	Mycobacterium marinum M	Mycobacterium smegmatis str. MC2 155 Gene: MSMEG_4662: 5-keto-2-deoxy-D-gluconate-6 phosphate aldolase (EC 4.1.2.29)	Mycobacterium sp. JLS	Mycobacterium tuberculosis H37Rv	Mycobacterium vanbaalenii PYR-1 Gene: Mvan_4017: 5-keto-2-deoxy-D-gluconate-6 phosphate aldolase (EC 4.1.2.29)	5-keto-2-deoxy-D-gluconate-6 phosphate aldolase (EC 4.1.2.29)
iolB	Mycobacterium abscessus ATCC 19977	Mycobacterium avium 104	Mycobacterium flavescens PYR-GCK Gene: Mflv_2600: 5-deoxy-glucuronate isomerase (EC 5.3.1.-)	Mycobacterium leprae TN	Mycobacterium marinum M	Mycobacterium smegmatis str. MC2 155 Gene: MSMEG_4663: 5-deoxy-glucuronate isomerase (EC 5.3.1.-)	Mycobacterium sp. JLS	Mycobacterium tuberculosis H37Rv	Mycobacterium vanbaalenii PYR-1 Gene: Mvan_4018: 5-deoxy-glucuronate isomerase (EC 5.3.1.-)	5-deoxy-glucuronate isomerase (EC 5.3.1.-)
iolD	Mycobacterium abscessus ATCC 19977	Mycobacterium avium 104	Mycobacterium flavescens PYR-GCK Gene: Mflv_2599: Epi-inositol hydrolase (EC 3.7.1.-)	Mycobacterium leprae TN	Mycobacterium marinum M	Mycobacterium smegmatis str. MC2 155 Gene: MSMEG_4664: Epi-inositol hydrolase (EC 3.7.1.-)	Mycobacterium sp. JLS	Mycobacterium tuberculosis H37Rv	Mycobacterium vanbaalenii PYR-1 Gene: Mvan_4019: Epi-inositol hydrolase (EC 3.7.1.-)	Epi-inositol hydrolase (EC 3.7.1.-)
iolG	Mycobacterium abscessus ATCC 19977	Mycobacterium avium 104	Mycobacterium flavescens PYR-GCK Gene: Mflv_2598: Myo-inositol 2-dehydrogenase (EC 1.1.1.18)	Mycobacterium leprae TN	Mycobacterium marinum M	Mycobacterium smegmatis str. MC2 155 Gene: MSMEG_4666: Myo-inositol 2-dehydrogenase (EC 1.1.1.18)	Mycobacterium sp. JLS	Mycobacterium tuberculosis H37Rv	2 Mycobacterium vanbaalenii PYR-1 Gene: Mvan_0387: Myo-inositol 2-dehydrogenase (EC 1.1.1.18) Gene: Mvan_4020: Myo-inositol 2-dehydrogenase (EC 1.1.1.18)	Myo-inositol 2-dehydrogenase (EC 1.1.1.18)

CRON 2.
iolTA	Mycobacterium abscessus ATCC 19977	Mycobacterium avium 104	* Mycobacterium flavescens PYR-GCK Site: position = -129 score = 5.28157 sequence = CTAATGTCAGGACAAACT Gene: Mflv_2605: Inositol ABC transport system sugar-binding protein	Mycobacterium leprae TN	Mycobacterium marinum M	* Mycobacterium smegmatis str. MC2 155 Site: position = -122 score = 4.83628 sequence = CTAATGTCATAACAAAGT Gene: MSMEG_4658: Inositol ABC transport system sugar-binding protein	Mycobacterium sp. JLS	Mycobacterium tuberculosis H37Rv	* Mycobacterium vanbaalenii PYR-1 Site: position = -130 score = 5.17908 sequence = CTAATGTCAGGACAAAGT Gene: Mvan_4011: Inositol ABC transport system sugar-binding protein	Inositol ABC transport system sugar-binding protein
iolTB	Mycobacterium abscessus ATCC 19977	Mycobacterium avium 104	Mycobacterium flavescens PYR-GCK Gene: Mflv_2606: Inositol ABC transport system permease protein	Mycobacterium leprae TN	Mycobacterium marinum M	Mycobacterium smegmatis str. MC2 155 Gene: MSMEG_4657: Inositol ABC transport system permease protein	Mycobacterium sp. JLS	Mycobacterium tuberculosis H37Rv	Mycobacterium vanbaalenii PYR-1 Gene: Mvan_4010: Inositol ABC transport system permease protein	Inositol ABC transport system permease protein
iolTC	Mycobacterium abscessus ATCC 19977	Mycobacterium avium 104	Mycobacterium flavescens PYR-GCK Gene: Mflv_2607: Inositol ABC transport system ATP-binding protein	Mycobacterium leprae TN	Mycobacterium marinum M	Mycobacterium smegmatis str. MC2 155 Gene: MSMEG_4656: Inositol ABC transport system ATP-binding protein	Mycobacterium sp. JLS	Mycobacterium tuberculosis H37Rv	Mycobacterium vanbaalenii PYR-1 Gene: Mvan_4009: Inositol ABC transport system ATP-binding protein	Inositol ABC transport system ATP-binding protein

CRON 3.
iolR	Mycobacterium abscessus ATCC 19977	Mycobacterium avium 104	* Mycobacterium flavescens PYR-GCK Site: position = -84 score = 5.36767 sequence = ACTTTGTCCTGACATTCT Gene: Mflv_2603: Inositol utilization transcriptional regulator, GntR family	Mycobacterium leprae TN	Mycobacterium marinum M	* Mycobacterium smegmatis str. MC2 155 Site: position = -109 score = 3.71282 sequence = CGTCTGTCAAGACTTTGT Site: position = -98 score = 5.08361 sequence = ACTTTGTTCTGACATTCT Gene: MSMEG_4659: Inositol utilization transcriptional regulator, GntR family	Mycobacterium sp. JLS	Mycobacterium tuberculosis H37Rv	* Mycobacterium vanbaalenii PYR-1 Site: position = -98 score = 3.77544 sequence = GCCATGTCAAGACTTTGT Site: position = -87 score = 5.36767 sequence = ACTTTGTCCTGACATTCT Gene: Mvan_4015: Inositol utilization transcriptional regulator, GntR family	Inositol utilization transcriptional regulator, GntR family

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog IolR - Mycobacteriaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --