Regulog IolR - Nocardiaceae

Properties
Regulator type:	Transcription factor
Regulator family:	GntR/Others
Regulation mode:
Biological process:	Inositol utilization
Effector:
Phylum:	Actinobacteria
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 21 sites [see more]

Member of regulog collections

By taxonomy - Nocardiaceae
By TF family - GntR/Others
By pathway - Inositol utilization

Statistics of regulated genes
Genome	Genes	Operons
Nocardia farcinica IFM 10152
Rhodococcus erythropolis PR4	10	3
Rhodococcus opacus B4	17	6
Rhodococcus sp. RHA1	17	6

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes					Function

CRON 1.
iolR	Nocardia farcinica IFM 10152	* Rhodococcus erythropolis PR4 Site: position = -134 score = 3.5459 sequence = TGCTTGTCAAGACTGACT Site: position = -35 score = 5.15013 sequence = AGTTTGTCTGGACATTAT Gene: RER_20220: Inositol utilization transcriptional regulator, GntR family	* Rhodococcus opacus B4 Site: position = -123 score = 3.3204 sequence = CTCCTGTCAAGACTTTGT Site: position = -112 score = 5.24232 sequence = ACTTTGTCCTGACATTAT Gene: ROP_10650: Inositol utilization transcriptional regulator, GntR family	* Rhodococcus sp. RHA1 Site: position = -122 score = 3.3204 sequence = CTCCTGTCAAGACTTTGT Site: position = -111 score = 5.24232 sequence = ACTTTGTCCTGACATTAT Gene: RHA1_ro01349: Inositol utilization transcriptional regulator, GntR family	Inositol utilization transcriptional regulator, GntR family
iolG3	Nocardia farcinica IFM 10152	Rhodococcus erythropolis PR4 Gene: RER_20230: Myo-inositol 2-dehydrogenase (EC 1.1.1.18)	* Rhodococcus opacus B4 Site: position = -89 score = 5.0002 sequence = ACTTTGTCCGCACAAACG Gene: ROP_36840: Myo-inositol 2-dehydrogenase (EC 1.1.1.18)	* Rhodococcus sp. RHA1 Site: position = -89 score = 4.94147 sequence = ACTTTGTCAGCACAAACG Gene: RHA1_ro03822: Myo-inositol 2-dehydrogenase (EC 1.1.1.18)	Myo-inositol 2-dehydrogenase (EC 1.1.1.18)
iolP	Nocardia farcinica IFM 10152	Rhodococcus erythropolis PR4 Gene: RER_20240: major facilitator family sugar permease	Rhodococcus opacus B4 Gene: ROP_10640: major facilitator family sugar permease	Rhodococcus sp. RHA1 Gene: RHA1_ro01348: major facilitator family sugar permease	major facilitator family sugar permease

CRON 2.
iolTA	Nocardia farcinica IFM 10152	* Rhodococcus erythropolis PR4 Site: position = -112 score = 4.99751 sequence = CTAATGTCAGAACAAACT Gene: RER_20340: Inositol ABC transport system sugar-binding protein	* Rhodococcus opacus B4 Site: position = -104 score = 5.08689 sequence = CTAATGTCCAGACAAACT Gene: ROP_10630: Inositol ABC transport system sugar-binding protein	* Rhodococcus sp. RHA1 Site: position = -105 score = 5.08689 sequence = CTAATGTCCAGACAAACT Gene: RHA1_ro01347: Inositol ABC transport system sugar-binding protein	Inositol ABC transport system sugar-binding protein
iolTB	Nocardia farcinica IFM 10152	Rhodococcus erythropolis PR4 Gene: RER_20350: Inositol ABC transport system permease protein	Rhodococcus opacus B4 Gene: ROP_10620: Inositol ABC transport system permease protein	Rhodococcus sp. RHA1 Gene: RHA1_ro01346: Inositol ABC transport system permease protein	Inositol ABC transport system permease protein
iolTC	Nocardia farcinica IFM 10152	Rhodococcus erythropolis PR4 Gene: RER_20360: Inositol ABC transport system ATP-binding protein	Rhodococcus opacus B4 Gene: ROP_10610: Inositol ABC transport system ATP-binding protein	Rhodococcus sp. RHA1 Gene: RHA1_ro01345: Inositol ABC transport system ATP-binding protein	Inositol ABC transport system ATP-binding protein

CRON 3.
oxiA	Nocardia farcinica IFM 10152	Rhodococcus erythropolis PR4	* Rhodococcus opacus B4 Site: position = -26 score = 4.29341 sequence = CGAATGTCTTAACATATA Gene: ROP_03440: putative myo-inositol 2-dehydrogenase	* Rhodococcus sp. RHA1 Site: position = -26 score = 4.29341 sequence = CGAATGTCTTAACATATA Gene: RHA1_ro00218: putative myo-inositol 2-dehydrogenase	putative myo-inositol 2-dehydrogenase

CRON 4.
iolT	Nocardia farcinica IFM 10152	Rhodococcus erythropolis PR4	2 Rhodococcus opacus B4* Site: position = -37 score = 4.93914 sequence = GCTTTGTCCGGACATAAA Gene: ROP_37590: Myo-inositol transporter, MFS family Gene: ROP_05270: Myo-inositol transporter, MFS family	* Rhodococcus sp. RHA1 Site: position = -61 score = 4.65508 sequence = GCTTTGTTCGGACATAAA Gene: RHA1_ro03889: Myo-inositol transporter, MFS family	Myo-inositol transporter, MFS family
usp	Nocardia farcinica IFM 10152	Rhodococcus erythropolis PR4	2 Rhodococcus opacus B4 Gene: ROP_37580: universal stress protein Gene: ROP_05280: universal stress protein	Rhodococcus sp. RHA1 Gene: RHA1_ro03888: universal stress protein	universal stress protein
iolG4	Nocardia farcinica IFM 10152	Rhodococcus erythropolis PR4	Rhodococcus opacus B4 Gene: ROP_37560: possible inositol 2-dehydrogenase	Rhodococcus sp. RHA1 Gene: RHA1_ro03887: possible inositol 2-dehydrogenase	possible inositol 2-dehydrogenase
iolG2	Nocardia farcinica IFM 10152	Rhodococcus erythropolis PR4	Rhodococcus opacus B4 Gene: ROP_37550: Myo-inositol 2-dehydrogenase (EC 1.1.1.18)	Rhodococcus sp. RHA1 Gene: RHA1_ro03886: Myo-inositol 2-dehydrogenase (EC 1.1.1.18)	Myo-inositol 2-dehydrogenase (EC 1.1.1.18)

CRON 5.
iolC	Nocardia farcinica IFM 10152	* Rhodococcus erythropolis PR4 Site: position = -8 score = 3.5459 sequence = AGTCAGTCTTGACAAGCA Site: position = -107 score = 5.15013 sequence = ATAATGTCCAGACAAACT Gene: RER_20210: 5-keto-2-deoxygluconokinase (EC 2.7.1.92)	* Rhodococcus opacus B4 Site: position = -109 score = 5.24232 sequence = ATAATGTCAGGACAAAGT Site: position = -98 score = 3.3204 sequence = ACAAAGTCTTGACAGGAG Gene: ROP_10660: 5-keto-2-deoxygluconokinase (EC 2.7.1.92)	* Rhodococcus sp. RHA1 Site: position = -37 score = 5.24232 sequence = ATAATGTCAGGACAAAGT Site: position = -26 score = 3.3204 sequence = ACAAAGTCTTGACAGGAG Gene: RHA1_ro01350: 5-keto-2-deoxygluconokinase (EC 2.7.1.92)	5-keto-2-deoxygluconokinase (EC 2.7.1.92)
iolJ	Nocardia farcinica IFM 10152	Rhodococcus erythropolis PR4 Gene: RER_20200: 5-keto-2-deoxy-D-gluconate-6 phosphate aldolase (EC 4.1.2.29)	Rhodococcus opacus B4 Gene: ROP_10670: 5-keto-2-deoxy-D-gluconate-6 phosphate aldolase (EC 4.1.2.29)	Rhodococcus sp. RHA1 Gene: RHA1_ro01351: 5-keto-2-deoxy-D-gluconate-6 phosphate aldolase (EC 4.1.2.29)	5-keto-2-deoxy-D-gluconate-6 phosphate aldolase (EC 4.1.2.29)
iolB	Nocardia farcinica IFM 10152	Rhodococcus erythropolis PR4 Gene: RER_20190: 5-deoxy-glucuronate isomerase (EC 5.3.1.-)	Rhodococcus opacus B4 Gene: ROP_10680: 5-deoxy-glucuronate isomerase (EC 5.3.1.-)	Rhodococcus sp. RHA1 Gene: RHA1_ro01352: 5-deoxy-glucuronate isomerase (EC 5.3.1.-)	5-deoxy-glucuronate isomerase (EC 5.3.1.-)
iolD	Nocardia farcinica IFM 10152	Rhodococcus erythropolis PR4 Gene: RER_20180: Epi-inositol hydrolase (EC 3.7.1.-)	Rhodococcus opacus B4 Gene: ROP_10690: Epi-inositol hydrolase (EC 3.7.1.-)	Rhodococcus sp. RHA1 Gene: RHA1_ro01353: Epi-inositol hydrolase (EC 3.7.1.-)	Epi-inositol hydrolase (EC 3.7.1.-)
iolE	Nocardia farcinica IFM 10152	Rhodococcus erythropolis PR4 Gene: RER_20170: Inosose dehydratase (EC 4.2.1.44)	Rhodococcus opacus B4 Gene: ROP_10700: Inosose dehydratase (EC 4.2.1.44)	Rhodococcus sp. RHA1 Gene: RHA1_ro01354: Inosose dehydratase (EC 4.2.1.44)	Inosose dehydratase (EC 4.2.1.44)
iolG	Nocardia farcinica IFM 10152	Rhodococcus erythropolis PR4 Gene: RER_20160: Myo-inositol 2-dehydrogenase (EC 1.1.1.18)	Rhodococcus opacus B4 Gene: ROP_10710: Myo-inositol 2-dehydrogenase (EC 1.1.1.18)	Rhodococcus sp. RHA1 Gene: RHA1_ro01355: Myo-inositol 2-dehydrogenase (EC 1.1.1.18)	Myo-inositol 2-dehydrogenase (EC 1.1.1.18)
iolH	Nocardia farcinica IFM 10152	Rhodococcus erythropolis PR4 Gene: RER_20150: putative sugar-phosphate epimerase/isomerase IolH	Rhodococcus opacus B4 Gene: ROP_10720: putative sugar-phosphate epimerase/isomerase IolH	Rhodococcus sp. RHA1 Gene: RHA1_ro01356: putative sugar-phosphate epimerase/isomerase IolH	putative sugar-phosphate epimerase/isomerase IolH
iolA	Nocardia farcinica IFM 10152	Rhodococcus erythropolis PR4 Gene: RER_20140: Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27)	Rhodococcus opacus B4 Gene: ROP_10730: Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27)	Rhodococcus sp. RHA1 Gene: RHA1_ro01357: Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27)	Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27)

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog IolR - Nocardiaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --