Collection of regulogs in Nocardiaceae taxonomic group
Genomes | 4 |
TF regulogs | 35 |
TF regulons | 114 |
TF binding sites | 381 |
RNA regulogs | 0 |
RNA regulons | 0 |
RNA sites | 0 |
This collection involves all regulons that were tentatively predicted by applying integrative comparative genomic approach to a single taxonomic group of closely-related genomes. To infer the regulons operated by transcription factors (TFs), we combined the identification of TF binding sites and cross-genome comparison of regulons with the analysis of the genomic and functional context of candidate target genes. To infer the regulons operated by regulatory RNAs such as riboswitches, we identified candidate RNA regulatory elements using HMM profiles and further analyzed their genomic and functional context.
TF | RNA | Total | ||||
---|---|---|---|---|---|---|
Genomes | Regulons | Sites | Regulons | Sites | Regulons | Sites |
Nocardia farcinica IFM 10152 | 24 | 68 | 0 | 0 | 24 | 68 |
Rhodococcus erythropolis PR4 | 28 | 82 | 0 | 0 | 28 | 82 |
Rhodococcus opacus B4 | 31 | 115 | 0 | 0 | 31 | 115 |
Rhodococcus sp. RHA1 | 31 | 116 | 0 | 0 | 31 | 116 |
Family | Type | Regulator | Function | ||||
---|---|---|---|---|---|---|---|
ArgR | TF | ArgR |
2
ArgR
Nocardia farcinica IFM 10152 |
1
ArgR
Rhodococcus erythropolis PR4 |
1
ArgR
Rhodococcus sp. RHA1 |
1
ArgR
Rhodococcus opacus B4 |
Arginine biosynthesis |
ArsR | TF | ArsR |
2
ArsR
Nocardia farcinica IFM 10152 |
2
ArsR
Rhodococcus erythropolis PR4 |
1
ArsR
Rhodococcus sp. RHA1 |
2
ArsR
Rhodococcus opacus B4 |
Arsenic resistance |
CsoR | TF | CsoR |
2
CsoR
Nocardia farcinica IFM 10152 |
2
CsoR
Rhodococcus erythropolis PR4 |
1
CsoR
Rhodococcus sp. RHA1 |
2
CsoR
Rhodococcus opacus B4 |
Copper resistance |
DtxR | TF | MntR |
1
MntR
Nocardia farcinica IFM 10152 |
3
MntR
Rhodococcus erythropolis PR4 |
3
MntR
Rhodococcus sp. RHA1 |
3
MntR
Rhodococcus opacus B4 |
Manganese homeostasis |
FUR | TF | Zur |
5
Zur
Nocardia farcinica IFM 10152 |
5
Zur
Rhodococcus erythropolis PR4 |
6
Zur
Rhodococcus sp. RHA1 |
6
Zur
Rhodococcus opacus B4 |
Zinc homeostasis |
GntR/MocR | TF | Nfa21130 |
1
Nfa21130
Nocardia farcinica IFM 10152 |
1
Nfa21130
Rhodococcus erythropolis PR4 |
1
Nfa21130
Rhodococcus sp. RHA1 |
1
Nfa21130
Rhodococcus opacus B4 |
Metabolite transport |
TF | PdxQ |
3
PdxQ
Rhodococcus erythropolis PR4 |
Pyridoxine/pyridoxal homeostasis; Metabolite transport | ||||
TF | PdxQ3 |
1
PdxQ3
Nocardia farcinica IFM 10152 |
Pyridoxine/pyridoxal homeostasis | ||||
TF | PdxR2 |
1
PdxR2
Nocardia farcinica IFM 10152 |
1
PdxR2
Rhodococcus erythropolis PR4 |
1
PdxR2
Rhodococcus sp. RHA1 |
1
PdxR2
Rhodococcus opacus B4 |
Pyridoxine/pyridoxal homeostasis | |
TF | PdxR3 |
2
PdxR3
Nocardia farcinica IFM 10152 |
2
PdxR3
Rhodococcus erythropolis PR4 |
3
PdxR3
Rhodococcus sp. RHA1 |
4
PdxR3
Rhodococcus opacus B4 |
Pyridoxine/pyridoxal homeostasis | |
TF | RHA1_ro08093 |
2
RHA1_ro08093
Rhodococcus sp. RHA1 |
|||||
TF | TauR |
5
TauR
Rhodococcus sp. RHA1 |
5
TauR
Rhodococcus opacus B4 |
Taurine utilization | |||
GntR/Others | TF | AnsR |
2
AnsR
Rhodococcus erythropolis PR4 |
2
AnsR
Rhodococcus sp. RHA1 |
2
AnsR
Rhodococcus opacus B4 |
Aspartate utilization; Asparagine degradation | |
TF | DasR |
2
DasR
Rhodococcus erythropolis PR4 |
2
DasR
Rhodococcus sp. RHA1 |
2
DasR
Rhodococcus opacus B4 |
N-acetylglucosamine utilization | ||
TF | HutC |
5
HutC
Nocardia farcinica IFM 10152 |
3
HutC
Rhodococcus erythropolis PR4 |
2
HutC
Rhodococcus sp. RHA1 |
2
HutC
Rhodococcus opacus B4 |
Histidine utilization | |
TF | IolR |
3
IolR
Rhodococcus erythropolis PR4 |
6
IolR
Rhodococcus sp. RHA1 |
6
IolR
Rhodococcus opacus B4 |
Inositol utilization | ||
TF | LldR |
2
LldR
Rhodococcus erythropolis PR4 |
2
LldR
Rhodococcus sp. RHA1 |
2
LldR
Rhodococcus opacus B4 |
Lactate utilization | ||
TF | Mce2R |
2
Mce2R
Nocardia farcinica IFM 10152 |
1
Mce2R
Rhodococcus erythropolis PR4 |
1
Mce2R
Rhodococcus sp. RHA1 |
1
Mce2R
Rhodococcus opacus B4 |
Fatty acid metabolism | |
TF | Nfa20840 |
1
Nfa20840
Nocardia farcinica IFM 10152 |
5
Nfa20840
Rhodococcus sp. RHA1 |
4
Nfa20840
Rhodococcus opacus B4 |
|||
TF | Nfa3720 |
1
Nfa3720
Nocardia farcinica IFM 10152 |
1
Nfa3720
Rhodococcus erythropolis PR4 |
1
Nfa3720
Rhodococcus opacus B4 |
Multidrug resistance; Multidrug efflux | ||
TF | PhnF |
3
PhnF
Nocardia farcinica IFM 10152 |
2
PhnF
Rhodococcus erythropolis PR4 |
2
PhnF
Rhodococcus sp. RHA1 |
2
PhnF
Rhodococcus opacus B4 |
Phosphonate utilization; 2-aminoethylphosphonate utilization | |
TF | RER_29210 |
1
RER_29210
Rhodococcus erythropolis PR4 |
1
RER_29210
Rhodococcus sp. RHA1 |
1
RER_29210
Rhodococcus opacus B4 |
Multidrug efflux | ||
TF | ROP_32700 |
2
ROP_32700
Rhodococcus sp. RHA1 |
2
ROP_32700
Rhodococcus opacus B4 |
||||
HrcA | TF | HrcA |
4
HrcA
Nocardia farcinica IFM 10152 |
4
HrcA
Rhodococcus erythropolis PR4 |
4
HrcA
Rhodococcus sp. RHA1 |
3
HrcA
Rhodococcus opacus B4 |
Heat shock response |
HxlR | TF | QorR |
2
QorR
Rhodococcus erythropolis PR4 |
2
QorR
Rhodococcus sp. RHA1 |
2
QorR
Rhodococcus opacus B4 |
Energy metabolism | |
IclR | TF | LtbR |
2
LtbR
Nocardia farcinica IFM 10152 |
2
LtbR
Rhodococcus erythropolis PR4 |
2
LtbR
Rhodococcus sp. RHA1 |
2
LtbR
Rhodococcus opacus B4 |
Leucine biosynthesis |
LacI | TF | RhaR |
1
RhaR
Nocardia farcinica IFM 10152 |
2
RhaR
Rhodococcus sp. RHA1 |
Rhamnose utilization | ||
LexA | TF | LexA |
6
LexA
Nocardia farcinica IFM 10152 |
8
LexA
Rhodococcus erythropolis PR4 |
7
LexA
Rhodococcus sp. RHA1 |
7
LexA
Rhodococcus opacus B4 |
SOS response |
NrdR | TF | NrdR |
2
NrdR
Nocardia farcinica IFM 10152 |
1
NrdR
Rhodococcus erythropolis PR4 |
1
NrdR
Rhodococcus sp. RHA1 |
1
NrdR
Rhodococcus opacus B4 |
Deoxyribonucleotide biosynthesis |
NrtR | TF | NrtR |
1
NrtR
Rhodococcus opacus B4 |
NAD biosynthesis | |||
Rex | TF | Rex |
2
Rex
Nocardia farcinica IFM 10152 |
4
Rex
Rhodococcus erythropolis PR4 |
8
Rex
Rhodococcus sp. RHA1 |
8
Rex
Rhodococcus opacus B4 |
Energy metabolism |
TetR | TF | AcnR |
2
AcnR
Nocardia farcinica IFM 10152 |
2
AcnR
Rhodococcus erythropolis PR4 |
2
AcnR
Rhodococcus sp. RHA1 |
2
AcnR
Rhodococcus opacus B4 |
Tricarboxylic acid cycle |
TF | AmtR |
2
AmtR
Nocardia farcinica IFM 10152 |
2
AmtR
Rhodococcus erythropolis PR4 |
1
AmtR
Rhodococcus sp. RHA1 |
2
AmtR
Rhodococcus opacus B4 |
Nitrogen metabolism | |
TF | BioQ |
4
BioQ
Nocardia farcinica IFM 10152 |
4
BioQ
Rhodococcus erythropolis PR4 |
5
BioQ
Rhodococcus sp. RHA1 |
6
BioQ
Rhodococcus opacus B4 |
Biotin biosynthesis | |
TF | PaaR |
4
PaaR
Nocardia farcinica IFM 10152 |
3
PaaR
Rhodococcus erythropolis PR4 |
5
PaaR
Rhodococcus sp. RHA1 |
4
PaaR
Rhodococcus opacus B4 |
Phenylacetic acid degradation |