Regulog Rex - Nocardiaceae

Properties
Regulator type:	Transcription factor
Regulator family:	Rex
Regulation mode:	repressor
Biological process:	Energy metabolism
Effector:	NADH
Phylum:	Actinobacteria
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 22 sites [see more]

Member of regulog collections

By taxonomy - Nocardiaceae
By trascription factor - Rex
By TF family - Rex
By effector - NADH
By pathway - Energy metabolism

Statistics of regulated genes
Genome	Genes	Operons
Nocardia farcinica IFM 10152	5	2
Rhodococcus erythropolis PR4	9	4
Rhodococcus opacus B4	35	8
Rhodococcus sp. RHA1	35	8

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes					Function

CRON 1.
pntAa	Nocardia farcinica IFM 10152 Gene: nfa10130: NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2)	Rhodococcus erythropolis PR4 Gene: RER_39990: NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2)	* Rhodococcus opacus B4 Site: position = -215 score = 4.66888 sequence = CTGTGATCGGGTTCACAA Gene: ROP_12860: NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2)	* Rhodococcus sp. RHA1 Site: position = -215 score = 4.9109 sequence = CTGTGACCGGGTTCACAA Gene: RHA1_ro01583: NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2)	NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2)
pntAb	Nocardia farcinica IFM 10152 Gene: nfa10140: NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2)	Rhodococcus erythropolis PR4 Gene: RER_39980: NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2)	Rhodococcus opacus B4 Gene: ROP_12850: NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2)	Rhodococcus sp. RHA1 Gene: RHA1_ro01582: NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2)	NAD(P) transhydrogenase alpha subunit (EC 1.6.1.2)
pntB	Nocardia farcinica IFM 10152 Gene: nfa10150: NAD(P) transhydrogenase subunit beta (EC 1.6.1.2)	Rhodococcus erythropolis PR4 Gene: RER_39970: NAD(P) transhydrogenase subunit beta (EC 1.6.1.2)	Rhodococcus opacus B4 Gene: ROP_12840: NAD(P) transhydrogenase subunit beta (EC 1.6.1.2)	Rhodococcus sp. RHA1 Gene: RHA1_ro01581: NAD(P) transhydrogenase subunit beta (EC 1.6.1.2)	NAD(P) transhydrogenase subunit beta (EC 1.6.1.2)

CRON 2.
coxM	Nocardia farcinica IFM 10152	Rhodococcus erythropolis PR4	* Rhodococcus opacus B4 Site: position = -17 score = 4.42949 sequence = TTGTGAGGTAGGTCACAA Gene: ROP_52770: Carbon monoxide dehydrogenase medium chain (EC 1.2.99.2)	* Rhodococcus sp. RHA1 Site: position = -17 score = 4.42949 sequence = TTGTGAGGTAGGTCACAA Gene: RHA1_ro05230: Carbon monoxide dehydrogenase medium chain (EC 1.2.99.2)	Carbon monoxide dehydrogenase medium chain (EC 1.2.99.2)
coxS	Nocardia farcinica IFM 10152	Rhodococcus erythropolis PR4	Rhodococcus opacus B4 Gene: ROP_52780: Carbon monoxide dehydrogenase small chain (EC 1.2.99.2)	Rhodococcus sp. RHA1 Gene: RHA1_ro05231: Carbon monoxide dehydrogenase small chain (EC 1.2.99.2)	Carbon monoxide dehydrogenase small chain (EC 1.2.99.2)
coxL	Nocardia farcinica IFM 10152	Rhodococcus erythropolis PR4	Rhodococcus opacus B4 Gene: ROP_52790: Carbon monoxide dehydrogenase form I, large chain( EC:1.2.99.2 )	Rhodococcus sp. RHA1 Gene: RHA1_ro05232: Carbon monoxide dehydrogenase form I, large chain( EC:1.2.99.2 )	Carbon monoxide dehydrogenase form I, large chain( EC:1.2.99.2 )
coxF	Nocardia farcinica IFM 10152	Rhodococcus erythropolis PR4	Rhodococcus opacus B4 Gene: ROP_52800: Carbon monoxide dehydrogenase F protein	Rhodococcus sp. RHA1 Gene: RHA1_ro05233: Carbon monoxide dehydrogenase F protein	Carbon monoxide dehydrogenase F protein
coxD	Nocardia farcinica IFM 10152	Rhodococcus erythropolis PR4	Rhodococcus opacus B4 Gene: ROP_52810: Carbon monoxide dehydrogenase D protein	Rhodococcus sp. RHA1 Gene: RHA1_ro05234: Carbon monoxide dehydrogenase D protein	Carbon monoxide dehydrogenase D protein
coxG	Nocardia farcinica IFM 10152	Rhodococcus erythropolis PR4	Rhodococcus opacus B4 Gene: ROP_52820: Carbon monoxide dehydrogenase G protein	Rhodococcus sp. RHA1 Gene: RHA1_ro05235: Carbon monoxide dehydrogenase G protein	Carbon monoxide dehydrogenase G protein
coxE	Nocardia farcinica IFM 10152	Rhodococcus erythropolis PR4	Rhodococcus opacus B4 Gene: ROP_52830: Carbon monoxide dehydrogenase E protein	Rhodococcus sp. RHA1 Gene: RHA1_ro05236: Carbon monoxide dehydrogenase E protein	Carbon monoxide dehydrogenase E protein

CRON 3.
rex	* Nocardia farcinica IFM 10152 Site: position = -179 score = 5.61866 sequence = TTGTGCATGGCTTCACAA Gene: nfa51710: Redox-sensitive transcriptional regulator Rex	* Rhodococcus erythropolis PR4 Site: position = -127 score = 5.77599 sequence = TTGTGCATGGGTTCACAA Gene: RER_16400: Redox-sensitive transcriptional regulator Rex	* Rhodococcus opacus B4 Site: position = -164 score = 5.77599 sequence = TTGTGCATGGGTTCACAA Gene: ROP_17260: Redox-sensitive transcriptional regulator Rex	* Rhodococcus sp. RHA1 Site: position = 22 score = 5.77599 sequence = TTGTGCATGGGTTCACAA Gene: RHA1_ro02054: Redox-sensitive transcriptional regulator Rex	Redox-sensitive transcriptional regulator Rex
hemA	Nocardia farcinica IFM 10152 Gene: nfa51700: Glutamyl-tRNA reductase (EC 1.2.1.70)	Rhodococcus erythropolis PR4 Gene: RER_16410: Glutamyl-tRNA reductase (EC 1.2.1.70)	Rhodococcus opacus B4 Gene: ROP_17250: Glutamyl-tRNA reductase (EC 1.2.1.70)	Rhodococcus sp. RHA1 Gene: RHA1_ro02053: Glutamyl-tRNA reductase (EC 1.2.1.70)	Glutamyl-tRNA reductase (EC 1.2.1.70)
hemC	Nocardia farcinica IFM 10152 Gene: nfa51690: Porphobilinogen deaminase (EC 2.5.1.61)	Rhodococcus erythropolis PR4 Gene: RER_16420: Porphobilinogen deaminase (EC 2.5.1.61)	Rhodococcus opacus B4 Gene: ROP_17240: Porphobilinogen deaminase (EC 2.5.1.61)	Rhodococcus sp. RHA1 Gene: RHA1_ro02052: Porphobilinogen deaminase (EC 2.5.1.61)	Porphobilinogen deaminase (EC 2.5.1.61)
hemD	Nocardia farcinica IFM 10152 Gene: nfa51680: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)	Rhodococcus erythropolis PR4 Gene: RER_16430: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)	Rhodococcus opacus B4 Gene: ROP_17230: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)	Rhodococcus sp. RHA1 Gene: RHA1_ro02051: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)	Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) / Uroporphyrinogen-III synthase (EC 4.2.1.75)
hemB	Nocardia farcinica IFM 10152 Gene: nfa51660: Porphobilinogen synthase (EC 4.2.1.24)	Rhodococcus erythropolis PR4 Gene: RER_16440: Porphobilinogen synthase (EC 4.2.1.24)	Rhodococcus opacus B4 Gene: ROP_17220: Porphobilinogen synthase (EC 4.2.1.24)	Rhodococcus sp. RHA1 Gene: RHA1_ro02050: Porphobilinogen synthase (EC 4.2.1.24)	Porphobilinogen synthase (EC 4.2.1.24)

CRON 4.
choD	Nocardia farcinica IFM 10152 Gene: nfa26130: Cholesterol oxidase (EC 1.1.3.6)	* Rhodococcus erythropolis PR4 Site: position = -69 score = 5.67643 sequence = TTGTGGTGGTAGTCACAA Gene: RER_19350: Cholesterol oxidase (EC 1.1.3.6)	* Rhodococcus opacus B4 Site: position = -71 score = 5.85569 sequence = TTGTGGCAGTTGTCACAA Gene: ROP_62610: Cholesterol oxidase (EC 1.1.3.6)	* Rhodococcus sp. RHA1 Site: position = -71 score = 5.85569 sequence = TTGTGGCAGCTGTCACAA Gene: RHA1_ro06201: Cholesterol oxidase (EC 1.1.3.6)	Cholesterol oxidase (EC 1.1.3.6)

CRON 5.
fadD	Nocardia farcinica IFM 10152	* Rhodococcus erythropolis PR4 Site: position = -89 score = 4.54318 sequence = TTGTGACTGTCGTCACGG Gene: RER_16190: Long-chain-fatty-acid--CoA ligase (EC: 6.2.1.3 )	* Rhodococcus opacus B4 Site: position = -9 score = 5.17655 sequence = CTGTGACTGGTGTCACAA Gene: ROP_17430: Long-chain-fatty-acid--CoA ligase (EC: 6.2.1.3 )	* Rhodococcus sp. RHA1 Site: position = -95 score = 5.24672 sequence = TTGTGACTGTTGTCACAG Gene: RHA1_ro02071: Long-chain-fatty-acid--CoA ligase (EC: 6.2.1.3 )	Long-chain-fatty-acid--CoA ligase (EC: 6.2.1.3 )
gpm	Nocardia farcinica IFM 10152	Rhodococcus erythropolis PR4 Gene: RER_16200: Phosphoglycerate mutase (EC 5.4.2.1)	Rhodococcus opacus B4 Gene: ROP_17420: Phosphoglycerate mutase (EC 5.4.2.1)	Rhodococcus sp. RHA1 Gene: RHA1_ro02070: Phosphoglycerate mutase (EC 5.4.2.1)	Phosphoglycerate mutase (EC 5.4.2.1)

CRON 6.
dhaS	Nocardia farcinica IFM 10152	Rhodococcus erythropolis PR4	* Rhodococcus opacus B4 Site: position = -40 score = 5.43269 sequence = TTGTGACAGCCATCACAA Gene: ROP_25550: Acetaldehyde dehydrogenase (EC 1.2.1.10)	* Rhodococcus sp. RHA1 Site: position = -40 score = 5.43269 sequence = TTGTGACAGCCATCACAA Gene: RHA1_ro02831: Acetaldehyde dehydrogenase (EC 1.2.1.10)	Acetaldehyde dehydrogenase (EC 1.2.1.10)
adhB	Nocardia farcinica IFM 10152 Gene: nfa20970: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent	Rhodococcus erythropolis PR4	Rhodococcus opacus B4 Gene: ROP_25560: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent	Rhodococcus sp. RHA1 Gene: RHA1_ro02832: Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent	Alcohol dehydrogenase (EC 1.1.1.1), Zn-dependent

CRON 7.
whiB	* Nocardia farcinica IFM 10152 Site: position = -106 score = 6.25815 sequence = TCGTGAAAGCATTCACAA Gene: nfa45800: WhiB-family transcriptional regulator involved in differentiation and sporulation	* Rhodococcus erythropolis PR4 Site: position = -106 score = 6.25815 sequence = TCGTGAAAGCATTCACAA Gene: RER_21900: WhiB-family transcriptional regulator involved in differentiation and sporulation	* Rhodococcus opacus B4 Site: position = -103 score = 6.25815 sequence = TCGTGAAAGCATTCACAA Gene: ROP_64060: WhiB-family transcriptional regulator involved in differentiation and sporulation	* Rhodococcus sp. RHA1 Site: position = -103 score = 6.25815 sequence = TCGTGAAAGCATTCACAA Gene: RHA1_ro06345: WhiB-family transcriptional regulator involved in differentiation and sporulation	WhiB-family transcriptional regulator involved in differentiation and sporulation

CRON 8.
nuoA	Nocardia farcinica IFM 10152 Gene: nfa26670: NADH ubiquinone oxidoreductase chain A (EC 1.6.5.3)	Rhodococcus erythropolis PR4 Gene: RER_27270: NADH ubiquinone oxidoreductase chain A (EC 1.6.5.3)	* Rhodococcus opacus B4 Site: position = -88 score = 3.94661 sequence = CTGTGGCATAACTCACAA Gene: ROP_59710: NADH ubiquinone oxidoreductase chain A (EC 1.6.5.3)	* Rhodococcus sp. RHA1 Site: position = -88 score = 3.94661 sequence = CTGTGGCATAACTCACAA Gene: RHA1_ro05909: NADH ubiquinone oxidoreductase chain A (EC 1.6.5.3)	NADH ubiquinone oxidoreductase chain A (EC 1.6.5.3)
nuoB	Nocardia farcinica IFM 10152 Gene: nfa26660: NADH-ubiquinone oxidoreductase chain B (EC 1.6.5.3)	Rhodococcus erythropolis PR4 Gene: RER_27260: NADH-ubiquinone oxidoreductase chain B (EC 1.6.5.3)	Rhodococcus opacus B4 Gene: ROP_59720: NADH-ubiquinone oxidoreductase chain B (EC 1.6.5.3)	Rhodococcus sp. RHA1 Gene: RHA1_ro05910: NADH-ubiquinone oxidoreductase chain B (EC 1.6.5.3)	NADH-ubiquinone oxidoreductase chain B (EC 1.6.5.3)
nuoC	Nocardia farcinica IFM 10152 Gene: nfa26650: NADH-ubiquinone oxidoreductase chain C (EC 1.6.5.3)	Rhodococcus erythropolis PR4 Gene: RER_27250: NADH-ubiquinone oxidoreductase chain C (EC 1.6.5.3)	Rhodococcus opacus B4 Gene: ROP_59730: NADH-ubiquinone oxidoreductase chain C (EC 1.6.5.3)	Rhodococcus sp. RHA1 Gene: RHA1_ro05911: NADH-ubiquinone oxidoreductase chain C (EC 1.6.5.3)	NADH-ubiquinone oxidoreductase chain C (EC 1.6.5.3)
nuoD	Nocardia farcinica IFM 10152 Gene: nfa26640: NADH-ubiquinone oxidoreductase chain D (EC 1.6.5.3)	Rhodococcus erythropolis PR4 Gene: RER_27240: NADH-ubiquinone oxidoreductase chain D (EC 1.6.5.3)	Rhodococcus opacus B4 Gene: ROP_59740: NADH-ubiquinone oxidoreductase chain D (EC 1.6.5.3)	Rhodococcus sp. RHA1 Gene: RHA1_ro05912: NADH-ubiquinone oxidoreductase chain D (EC 1.6.5.3)	NADH-ubiquinone oxidoreductase chain D (EC 1.6.5.3)
nuoE	Nocardia farcinica IFM 10152 Gene: nfa26630: NADH-ubiquinone oxidoreductase chain E (EC 1.6.5.3)	Rhodococcus erythropolis PR4 Gene: RER_27230: NADH-ubiquinone oxidoreductase chain E (EC 1.6.5.3)	Rhodococcus opacus B4 Gene: ROP_59750: NADH-ubiquinone oxidoreductase chain E (EC 1.6.5.3)	Rhodococcus sp. RHA1 Gene: RHA1_ro05913: NADH-ubiquinone oxidoreductase chain E (EC 1.6.5.3)	NADH-ubiquinone oxidoreductase chain E (EC 1.6.5.3)
nuoF	Nocardia farcinica IFM 10152 Gene: nfa26620: NADH-ubiquinone oxidoreductase chain F (EC 1.6.5.3)	Rhodococcus erythropolis PR4 Gene: RER_27220: NADH-ubiquinone oxidoreductase chain F (EC 1.6.5.3)	Rhodococcus opacus B4 Gene: ROP_59760: NADH-ubiquinone oxidoreductase chain F (EC 1.6.5.3)	Rhodococcus sp. RHA1 Gene: RHA1_ro05914: NADH-ubiquinone oxidoreductase chain F (EC 1.6.5.3)	NADH-ubiquinone oxidoreductase chain F (EC 1.6.5.3)
nuoG	Nocardia farcinica IFM 10152 Gene: nfa26610: NADH-ubiquinone oxidoreductase chain G (EC 1.6.5.3)	Rhodococcus erythropolis PR4 Gene: RER_27210: NADH-ubiquinone oxidoreductase chain G (EC 1.6.5.3)	Rhodococcus opacus B4 Gene: ROP_59770: NADH-ubiquinone oxidoreductase chain G (EC 1.6.5.3)	Rhodococcus sp. RHA1 Gene: RHA1_ro05915: NADH-ubiquinone oxidoreductase chain G (EC 1.6.5.3)	NADH-ubiquinone oxidoreductase chain G (EC 1.6.5.3)
nuoH	Nocardia farcinica IFM 10152 Gene: nfa26600: NADH-ubiquinone oxidoreductase chain H (EC 1.6.5.3)	Rhodococcus erythropolis PR4 Gene: RER_27200: NADH-ubiquinone oxidoreductase chain H (EC 1.6.5.3)	Rhodococcus opacus B4 Gene: ROP_59780: NADH-ubiquinone oxidoreductase chain H (EC 1.6.5.3)	Rhodococcus sp. RHA1 Gene: RHA1_ro05916: NADH-ubiquinone oxidoreductase chain H (EC 1.6.5.3)	NADH-ubiquinone oxidoreductase chain H (EC 1.6.5.3)
nuoI	Nocardia farcinica IFM 10152	Rhodococcus erythropolis PR4 Gene: RER_27190: NADH-quinone oxidoreductase chain I	Rhodococcus opacus B4 Gene: ROP_59790: NADH-quinone oxidoreductase chain I	Rhodococcus sp. RHA1 Gene: RHA1_ro05917: NADH-quinone oxidoreductase chain I	NADH-quinone oxidoreductase chain I
nuoJ	Nocardia farcinica IFM 10152 Gene: nfa26590: NADH-ubiquinone oxidoreductase chain J (EC 1.6.5.3)	Rhodococcus erythropolis PR4 Gene: RER_27180: NADH-ubiquinone oxidoreductase chain J (EC 1.6.5.3)	Rhodococcus opacus B4 Gene: ROP_59800: NADH-ubiquinone oxidoreductase chain J (EC 1.6.5.3)	Rhodococcus sp. RHA1 Gene: RHA1_ro05918: NADH-ubiquinone oxidoreductase chain J (EC 1.6.5.3)	NADH-ubiquinone oxidoreductase chain J (EC 1.6.5.3)
nuoK	Nocardia farcinica IFM 10152 Gene: nfa26580: NADH-ubiquinone oxidoreductase chain K (EC 1.6.5.3)	Rhodococcus erythropolis PR4 Gene: RER_27170: NADH-ubiquinone oxidoreductase chain K (EC 1.6.5.3)	Rhodococcus opacus B4 Gene: ROP_59810: NADH-ubiquinone oxidoreductase chain K (EC 1.6.5.3)	Rhodococcus sp. RHA1 Gene: RHA1_ro05919: NADH-ubiquinone oxidoreductase chain K (EC 1.6.5.3)	NADH-ubiquinone oxidoreductase chain K (EC 1.6.5.3)
nuoL	Nocardia farcinica IFM 10152 Gene: nfa26570: NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3)	Rhodococcus erythropolis PR4 Gene: RER_27160: NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3)	Rhodococcus opacus B4 Gene: ROP_59820: NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3)	Rhodococcus sp. RHA1 Gene: RHA1_ro05920: NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3)	NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3)
nuoM	Nocardia farcinica IFM 10152 Gene: nfa26560: NADH-ubiquinone oxidoreductase chain M (EC 1.6.5.3)	Rhodococcus erythropolis PR4 Gene: RER_27150: NADH-ubiquinone oxidoreductase chain M (EC 1.6.5.3)	Rhodococcus opacus B4 Gene: ROP_59830: NADH-ubiquinone oxidoreductase chain M (EC 1.6.5.3)	Rhodococcus sp. RHA1 Gene: RHA1_ro05921: NADH-ubiquinone oxidoreductase chain M (EC 1.6.5.3)	NADH-ubiquinone oxidoreductase chain M (EC 1.6.5.3)
nuoN	Nocardia farcinica IFM 10152 Gene: nfa26550: NADH-ubiquinone oxidoreductase chain N (EC 1.6.5.3)	Rhodococcus erythropolis PR4 Gene: RER_27140: NADH-ubiquinone oxidoreductase chain N (EC 1.6.5.3)	Rhodococcus opacus B4 Gene: ROP_59840: NADH-ubiquinone oxidoreductase chain N (EC 1.6.5.3)	Rhodococcus sp. RHA1 Gene: RHA1_ro05922: NADH-ubiquinone oxidoreductase chain N (EC 1.6.5.3)	NADH-ubiquinone oxidoreductase chain N (EC 1.6.5.3)

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog Rex - Nocardiaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --