Regulog IolR - Streptomycetaceae
| Regulator type: | Transcription factor |
| Regulator family: | GntR/Others |
| Regulation mode: | |
| Biological process: | Inositol utilization |
| Effector: | |
| Phylum: | Actinobacteria |
| Visualization: | |
|
Allows to visualize regulog content in the context of metabolic pathways |
Member of regulog collections
- By taxonomy - Streptomycetaceae
- By TF family - GntR/Others
- By pathway - Inositol utilization
| Genome | Genes | Operons |
|---|---|---|
| Streptomyces avermitilis MA-4680 | 24 | 7 |
| Streptomyces coelicolor A3(2) | 24 | 10 |
| Streptomyces griseus subsp. griseus NBRC 13350 | 11 | 5 |
| Streptomyces scabiei 87.22 | 13 | 6 |
| Genes | Function | ||||
|---|---|---|---|---|---|
| CRON 1. | |||||
| iolTA2 |
*
Streptomyces avermitilis MA-4680 Site: position = -75 score = 3.01748 sequence = CCGATGTCCGGATGCACG Gene: SAV_1983: Inositol ABC transport system, sugar-binding protein |
*
Streptomyces coelicolor A3(2) Site: position = -153 score = 4.92093 sequence = GCAATGTCCGGACAATGT Gene: SCO6257: Inositol ABC transport system, sugar-binding protein |
*
Streptomyces griseus subsp. griseus NBRC 13350 Site: position = -192 score = 3.5129 sequence = GGTAGGTCCGGACACCTG Gene: SGR_1275: Inositol ABC transport system, sugar-binding protein |
|
Inositol ABC transport system, sugar-binding protein |
| iolTB2 |
Gene: SAV_1982: Inositol ABC transport system, permease protein |
Gene: SCO6258: Inositol ABC transport system, permease protein |
Gene: SGR_1274: Inositol ABC transport system, permease protein |
|
Inositol ABC transport system, permease protein |
| iolTC2 |
Gene: SAV_1981: Inositol ABC transport system, ATP-binding protein |
Gene: SCO6259: Inositol ABC transport system, ATP-binding protein |
Gene: SGR_1273: Inositol ABC transport system, ATP-binding protein |
|
Inositol ABC transport system, ATP-binding protein |
| CRON 2. | |||||
| iolG3 |
Gene: SAV_7155: Myo-inositol 2-dehydrogenase (EC 1.1.1.18) |
*
Streptomyces coelicolor A3(2) Site: position = -103 score = 4.60126 sequence = TCTTTGTCCTGTCAAAAG Gene: SCO6988: Myo-inositol 2-dehydrogenase (EC 1.1.1.18) |
|
Gene: SCAB_19091: Myo-inositol 2-dehydrogenase (EC 1.1.1.18) |
Myo-inositol 2-dehydrogenase (EC 1.1.1.18) |
| CRON 3. | |||||
| iolC |
*2
Streptomyces avermitilis MA-4680 Site: position = -78 score = 4.84431 sequence = CGAATGTCTGGACAAAAC Gene: SAV_5338: 5-keto-2-deoxygluconokinase (EC 2.7.1.92) Site: position = -147 score = 4.52018 sequence = ACTTTGTTAAGACATCAT Site: position = -115 score = 5.0903 sequence = CGAATGTCCGTACAAACT Gene: SAV_7150: 5-keto-2-deoxygluconokinase (EC 2.7.1.92) |
*
Streptomyces coelicolor A3(2) Site: position = -123 score = 4.80425 sequence = ACTTTGTCAAGACATCAT Site: position = -91 score = 4.55373 sequence = CGAATGTAAGTACAAAGT Gene: SCO6978: 5-keto-2-deoxygluconokinase (EC 2.7.1.92) |
*
Streptomyces griseus subsp. griseus NBRC 13350 Site: position = -82 score = 5.3403 sequence = CGAATGTCCGGACAAAAT Gene: SGR_4834: 5-keto-2-deoxygluconokinase (EC 2.7.1.92) |
*
Streptomyces scabiei 87.22 Site: position = -79 score = 5.10975 sequence = CGAATGTCTGGACAAAGT Gene: SCAB_58891: 5-keto-2-deoxygluconokinase (EC 2.7.1.92) |
5-keto-2-deoxygluconokinase (EC 2.7.1.92) |
| iolJ |
2
Streptomyces avermitilis MA-4680 Gene: SAV_5339: 5-keto-2-deoxy-D-gluconate-6 phosphate aldolase (EC 4.1.2.29) Gene: SAV_7149: 5-keto-2-deoxy-D-gluconate-6 phosphate aldolase (EC 4.1.2.29) |
Gene: SCO6977: 5-keto-2-deoxy-D-gluconate-6 phosphate aldolase (EC 4.1.2.29) |
Gene: SGR_4835: 5-keto-2-deoxy-D-gluconate-6 phosphate aldolase (EC 4.1.2.29) |
Gene: SCAB_58901: 5-keto-2-deoxy-D-gluconate-6 phosphate aldolase (EC 4.1.2.29) |
5-keto-2-deoxy-D-gluconate-6 phosphate aldolase (EC 4.1.2.29) |
| iolB |
2
Streptomyces avermitilis MA-4680 Gene: SAV_5340: 5-deoxy-glucuronate isomerase (EC 5.3.1.-) Gene: SAV_7148: 5-deoxy-glucuronate isomerase (EC 5.3.1.-) |
Gene: SCO6976: 5-deoxy-glucuronate isomerase (EC 5.3.1.-) |
Gene: SGR_4836: 5-deoxy-glucuronate isomerase (EC 5.3.1.-) |
Gene: SCAB_58911: 5-deoxy-glucuronate isomerase (EC 5.3.1.-) |
5-deoxy-glucuronate isomerase (EC 5.3.1.-) |
| iolD |
2
Streptomyces avermitilis MA-4680 Gene: SAV_5341: Epi-inositol hydrolase (EC 3.7.1.-) Gene: SAV_7147: Epi-inositol hydrolase (EC 3.7.1.-) |
*2
Streptomyces coelicolor A3(2) Gene: SCO6975: Epi-inositol hydrolase (EC 3.7.1.-) Site: position = -86 score = 5.09772 sequence = CGAATGTCCGGACAAAAC Gene: SCO2727: Epi-inositol hydrolase (EC 3.7.1.-) |
Gene: SGR_4837: Epi-inositol hydrolase (EC 3.7.1.-) |
Gene: SCAB_58921: Epi-inositol hydrolase (EC 3.7.1.-) |
Epi-inositol hydrolase (EC 3.7.1.-) |
| iolA |
Gene: SAV_5342: Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) |
Gene: SCO2726: Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) |
Gene: SGR_4838: Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) |
Gene: SCAB_58931: Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) |
Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) |
| iolR |
Gene: SAV_7146: Inositol utilization transcriptional regulator, GntR family |
*2
Streptomyces coelicolor A3(2) Gene: SCO6974: Inositol utilization transcriptional regulator, GntR family Site: position = -91 score = 5.40241 sequence = CGTATGTCCGGACAATCG Gene: SCO6256: Inositol utilization transcriptional regulator, GntR family |
*
Streptomyces griseus subsp. griseus NBRC 13350 Site: position = -33 score = 5.06766 sequence = GCTTTGTCCGGACAAGCG Site: position = -93 score = 5.31526 sequence = CGTTTGTCCTGACAAATG Gene: SGR_1276: Inositol utilization transcriptional regulator, GntR family |
*
Streptomyces scabiei 87.22 Site: position = -65 score = 4.66944 sequence = CTCATGTCAGGACAATGC Gene: SCAB_19081: Inositol utilization transcriptional regulator, GntR family |
Inositol utilization transcriptional regulator, GntR family |
| CRON 4. | |||||
| iolE |
*
Streptomyces avermitilis MA-4680 Site: position = -72 score = 4.84431 sequence = GTTTTGTCCAGACATTCG Gene: SAV_5337: Inosose dehydratase (EC 4.2.1.44) |
|
*
Streptomyces griseus subsp. griseus NBRC 13350 Site: position = -64 score = 5.3403 sequence = ATTTTGTCCGGACATTCG Gene: SGR_4833: Inosose dehydratase (EC 4.2.1.44) |
*
Streptomyces scabiei 87.22 Site: position = -63 score = 5.10975 sequence = ACTTTGTCCAGACATTCG Gene: SCAB_58881: Inosose dehydratase (EC 4.2.1.44) |
Inosose dehydratase (EC 4.2.1.44) |
| CRON 5. | |||||
| iolG |
*
Streptomyces avermitilis MA-4680 Site: position = -55 score = 5.09215 sequence = CGGTTGTCCGGACAAACC Gene: SAV_1985: Inositol 2-dehydrogenase (EC 1.1.1.18 ) |
*
Streptomyces coelicolor A3(2) Site: position = -55 score = 5.40241 sequence = CGATTGTCCGGACATACG Gene: SCO6255: Inositol 2-dehydrogenase (EC 1.1.1.18 ) |
*
Streptomyces griseus subsp. griseus NBRC 13350 Site: position = -116 score = 5.06766 sequence = CGCTTGTCCGGACAAAGC Site: position = -56 score = 5.31526 sequence = CATTTGTCAGGACAAACG Gene: SGR_1277: Inositol 2-dehydrogenase (EC 1.1.1.18 ) |
*
Streptomyces scabiei 87.22 Site: position = -56 score = 4.98966 sequence = CGGTTGTCCGGACAAAGC Gene: SCAB_18231: Inositol 2-dehydrogenase (EC 1.1.1.18 ) |
Inositol 2-dehydrogenase (EC 1.1.1.18 ) |
| CRON 6. | |||||
| iolR1 |
*
Streptomyces avermitilis MA-4680 Site: position = -79 score = 5.09215 sequence = GGTTTGTCCGGACAACCG Gene: SAV_1984: Inositol utilization transcriptional regulator, GntR family |
|
|
*
Streptomyces scabiei 87.22 Site: position = -91 score = 4.98966 sequence = GCTTTGTCCGGACAACCG Gene: SCAB_18221: Inositol utilization transcriptional regulator, GntR family |
Inositol utilization transcriptional regulator, GntR family |
| iolTA |
Gene: SAV_1983: Inositol ABC transport system sugar-binding protein |
*
Streptomyces coelicolor A3(2) Site: position = -153 score = 4.92093 sequence = GCAATGTCCGGACAATGT Gene: SCO6257: Inositol ABC transport system sugar-binding protein |
Gene: SGR_1275: Inositol ABC transport system sugar-binding protein |
|
Inositol ABC transport system sugar-binding protein |
| iolTB |
Gene: SAV_1982: Inositol ABC transport system permease protein |
Gene: SCO6258: Inositol ABC transport system permease protein |
Gene: SGR_1274: Inositol ABC transport system permease protein |
|
Inositol ABC transport system permease protein |
| iolTC |
Gene: SAV_1981: Inositol ABC transport system ATP-binding protein |
Gene: SCO6259: Inositol ABC transport system ATP-binding protein |
Gene: SGR_1273: Inositol ABC transport system ATP-binding protein |
|
Inositol ABC transport system ATP-binding protein |
| SCO6259 |
Gene: SAV_1980: Putative sugar kinase |
Gene: SCO6260: Putative sugar kinase |
Gene: SGR_1272: Putative sugar kinase |
Gene: SCAB_18211: Putative sugar kinase |
Putative sugar kinase |
| CRON 7. | |||||
| SCO6985 |
Gene: SAV_7190: Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin |
*
Streptomyces coelicolor A3(2) Site: position = -57 score = 4.94892 sequence = CGTTTGTCAGGACAAGAA Gene: SCO6985: Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin |
|
Gene: SCAB_79031: Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin |
Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin |
| iolG2 |
Gene: SAV_7188: Myo-inositol 2-dehydrogenase 1 (EC 1.1.1.18) |
Gene: SCO6984: Myo-inositol 2-dehydrogenase 1 (EC 1.1.1.18) |
|
Gene: SCAB_16031: Myo-inositol 2-dehydrogenase 1 (EC 1.1.1.18) |
Myo-inositol 2-dehydrogenase 1 (EC 1.1.1.18) |
| CRON 8. | |||||
| iolR2 |
Gene: SAV_7191: Transcriptional regulator for inositol utilization, LacI family |
*
Streptomyces coelicolor A3(2) Site: position = -90 score = 4.94892 sequence = TTCTTGTCCTGACAAACG Gene: SCO6986: Transcriptional regulator for inositol utilization, LacI family |
|
Gene: SCAB_16011: Transcriptional regulator for inositol utilization, LacI family |
Transcriptional regulator for inositol utilization, LacI family |
| CRON 9. | |||||
| iolTA2 |
*
Streptomyces avermitilis MA-4680 Site: position = -178 score = 4.52018 sequence = ATGATGTCTTAACAAAGT Site: position = -210 score = 5.0903 sequence = AGTTTGTACGGACATTCG Gene: SAV_7151: Inositol ABC transport system sugar-binding protein |
*
Streptomyces coelicolor A3(2) Site: position = -148 score = 4.80425 sequence = ATGATGTCTTGACAAAGT Site: position = -180 score = 4.55373 sequence = ACTTTGTACTTACATTCG Gene: SCO6979: Inositol ABC transport system sugar-binding protein |
|
*
Streptomyces scabiei 87.22 Site: position = -216 score = 4.70485 sequence = ATAATGTCTTAACAAAGT Site: position = -248 score = 4.56508 sequence = GCTTTGTACTGACATCCT Gene: SCAB_19051: Inositol ABC transport system sugar-binding protein |
Inositol ABC transport system sugar-binding protein |
| iolTB2 |
Gene: SAV_7152: Inositol ABC transport system permease protein |
Gene: SCO6980: Inositol ABC transport system permease protein |
|
Gene: SCAB_19041: Inositol ABC transport system permease protein |
Inositol ABC transport system permease protein |
| iolTC2 |
Gene: SAV_7153: Inositol ABC transport system ATP-binding protein |
Gene: SCO6981: Inositol ABC transport system ATP-binding protein |
|
Gene: SCAB_19031: Inositol ABC transport system ATP-binding protein |
Inositol ABC transport system ATP-binding protein |
| iolE2 |
Gene: SAV_7154: Inosose dehydratase (EC 4.2.1.44) |
Gene: SCO6982: Inosose dehydratase (EC 4.2.1.44) |
|
|
Inosose dehydratase (EC 4.2.1.44) |
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
|
Regulatory Sites | [ FASTA format ] | DOWNLOAD |