Regulog MlnR - Various betaproteobacteria

Properties
Regulator type:	Transcription factor
Regulator family:	GntR/Others
Regulation mode:
Biological process:	Malonate metabolism
Effector:
Phylum:	Proteobacteria/Beta
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 14 sites [see more]

Member of regulog collections

By taxonomy - Various betaproteobacteria
By TF family - GntR/Others
By pathway - Malonate metabolism

Statistics of regulated genes
Genome	Genes	Operons
Methylobacillus flagellatus KT
Methylophilales bacterium HTCC2181
Methylotenera mobilis JLW8
Nitrosomonas europaea ATCC 19718
Nitrosospira multiformis ATCC 25196
Thiobacillus denitrificans
Azoarcus sp. EbN1	6	2
Dechloromonas aromatica RCB	12	6
Thauera sp. MZ1T	6	4
Chromobacterium violaceum ATCC 12472
Laribacter hongkongensis HLHK9
Neisseria meningitidis MC58

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes													Function

CRON 1.
mlnR	Methylobacillus flagellatus KT	Methylophilales bacterium HTCC2181	Methylotenera mobilis JLW8	Nitrosomonas europaea ATCC 19718	Nitrosospira multiformis ATCC 25196	Thiobacillus denitrificans	* Azoarcus sp. EbN1 Site: position = -74 score = 5.85352 sequence = TTATCCATAATTATGAGTGC Gene: ebA3736: Transcriptional regulator of malonate metabolism, GntR family	* Dechloromonas aromatica RCB Site: position = -29 score = 5.5987 sequence = GTATCCATAATTATGGAAGC Gene: Daro_4007: Transcriptional regulator of malonate metabolism, GntR family	* Thauera sp. MZ1T Site: position = -176 score = 6.31666 sequence = TTATCCATAATTATGAATGC Gene: Tmz1t_3487: Transcriptional regulator of malonate metabolism, GntR family	Chromobacterium violaceum ATCC 12472	Laribacter hongkongensis HLHK9	Neisseria meningitidis MC58	Transcriptional regulator of malonate metabolism, GntR family

CRON 2.
ebA7223	Methylobacillus flagellatus KT	Methylophilales bacterium HTCC2181	Methylotenera mobilis JLW8	Nitrosomonas europaea ATCC 19718	Nitrosospira multiformis ATCC 25196	Thiobacillus denitrificans	Azoarcus sp. EbN1 Gene: ebA7223: YhdH, a putative quinone oxidoreductase	* Dechloromonas aromatica RCB Site: position = -49 score = 5.96971 sequence = TCATTCGTAATTATGAATAC Gene: Daro_1202: YhdH, a putative quinone oxidoreductase	* Thauera sp. MZ1T Site: position = -64 score = 4.8576 sequence = GCGGCTATAATTATGAATCA Gene: Tmz1t_1612: YhdH, a putative quinone oxidoreductase	Chromobacterium violaceum ATCC 12472	Laribacter hongkongensis HLHK9	Neisseria meningitidis MC58	YhdH, a putative quinone oxidoreductase
Daro_1330	Methylobacillus flagellatus KT	Methylophilales bacterium HTCC2181	Methylotenera mobilis JLW8	Nitrosomonas europaea ATCC 19718	Nitrosospira multiformis ATCC 25196	Thiobacillus denitrificans	Azoarcus sp. EbN1	2 Dechloromonas aromatica RCB Gene: Daro_1330: Two-component hybrid sensor and regulator Gene: Daro_1203: Two-component hybrid sensor and regulator	Thauera sp. MZ1T Gene: Tmz1t_1613: Two-component hybrid sensor and regulator	Chromobacterium violaceum ATCC 12472	Laribacter hongkongensis HLHK9	Neisseria meningitidis MC58	Two-component hybrid sensor and regulator
prpE	Methylobacillus flagellatus KT	Methylophilales bacterium HTCC2181	Methylotenera mobilis JLW8	Nitrosomonas europaea ATCC 19718	Nitrosospira multiformis ATCC 25196	Thiobacillus denitrificans	Azoarcus sp. EbN1 Gene: ebA7220: Propionate-CoA ligase	Dechloromonas aromatica RCB Gene: Daro_1204: Propionate-CoA ligase	Thauera sp. MZ1T Gene: Tmz1t_1614: Propionate-CoA ligase	Chromobacterium violaceum ATCC 12472	Laribacter hongkongensis HLHK9 Gene: LHK_02062: Propionate-CoA ligase	Neisseria meningitidis MC58	Propionate-CoA ligase

CRON 3.
epi	Methylobacillus flagellatus KT	Methylophilales bacterium HTCC2181	Methylotenera mobilis JLW8	Nitrosomonas europaea ATCC 19718	Nitrosospira multiformis ATCC 25196 Gene: Nmul_A0281: Methylmalonyl-CoA epimerase (EC 5.1.99.1)	Thiobacillus denitrificans	Azoarcus sp. EbN1 Gene: ebA3749: Methylmalonyl-CoA epimerase (EC 5.1.99.1)	* Dechloromonas aromatica RCB Site: position = -50 score = 4.75095 sequence = ATCCCTATAATTATGGATTA Gene: Daro_0300: Methylmalonyl-CoA epimerase (EC 5.1.99.1)	* Thauera sp. MZ1T Site: position = -49 score = 5.70978 sequence = TCCTCTATAATTATGAATTC Gene: Tmz1t_1139: Methylmalonyl-CoA epimerase (EC 5.1.99.1)	Chromobacterium violaceum ATCC 12472 Gene: CV3928: Methylmalonyl-CoA epimerase (EC 5.1.99.1)	Laribacter hongkongensis HLHK9	Neisseria meningitidis MC58	Methylmalonyl-CoA epimerase (EC 5.1.99.1)

CRON 4.
ebA3691	Methylobacillus flagellatus KT	Methylophilales bacterium HTCC2181	Methylotenera mobilis JLW8	Nitrosomonas europaea ATCC 19718	Nitrosospira multiformis ATCC 25196	Thiobacillus denitrificans	Azoarcus sp. EbN1 Gene: ebA3691: Enoyl-CoA hydratase (EC 4.2.1.17)	* Dechloromonas aromatica RCB Site: position = -113 score = 4.29429 sequence = TAATTAATAATTACCGTAAA Site: position = -120 score = 4.66108 sequence = TCCTCCCTAATTAATAATTA Gene: Daro_4012: Enoyl-CoA hydratase (EC 4.2.1.17)	Thauera sp. MZ1T Gene: Tmz1t_3491: Enoyl-CoA hydratase (EC 4.2.1.17)	Chromobacterium violaceum ATCC 12472	Laribacter hongkongensis HLHK9	Neisseria meningitidis MC58	Enoyl-CoA hydratase (EC 4.2.1.17)

CRON 5.
mutB	Methylobacillus flagellatus KT	Methylophilales bacterium HTCC2181	Methylotenera mobilis JLW8	Nitrosomonas europaea ATCC 19718	Nitrosospira multiformis ATCC 25196	Thiobacillus denitrificans	* Azoarcus sp. EbN1 Site: position = -298 score = 5.85352 sequence = GCACTCATAATTATGGATAA Gene: ebA3738: Methylmalonyl-CoA mutase (EC 5.4.99.2)	* Dechloromonas aromatica RCB Site: position = -121 score = 5.5987 sequence = GCTTCCATAATTATGGATAC Gene: Daro_4006: Methylmalonyl-CoA mutase (EC 5.4.99.2)	* Thauera sp. MZ1T Site: position = -254 score = 6.31666 sequence = GCATTCATAATTATGGATAA Gene: Tmz1t_3486: Methylmalonyl-CoA mutase (EC 5.4.99.2)	Chromobacterium violaceum ATCC 12472	Laribacter hongkongensis HLHK9	Neisseria meningitidis MC58	Methylmalonyl-CoA mutase (EC 5.4.99.2)
ebA3739	Methylobacillus flagellatus KT	Methylophilales bacterium HTCC2181	Methylotenera mobilis JLW8	Nitrosomonas europaea ATCC 19718	Nitrosospira multiformis ATCC 25196	Thiobacillus denitrificans	Azoarcus sp. EbN1 Gene: ebA3739: hypothetical protein	Dechloromonas aromatica RCB	Thauera sp. MZ1T	Chromobacterium violaceum ATCC 12472	Laribacter hongkongensis HLHK9	Neisseria meningitidis MC58	hypothetical protein
meaB	Methylobacillus flagellatus KT	Methylophilales bacterium HTCC2181	Methylotenera mobilis JLW8	Nitrosomonas europaea ATCC 19718	Nitrosospira multiformis ATCC 25196	Thiobacillus denitrificans	Azoarcus sp. EbN1 Gene: ebA3741: auxiliary metallochaperone, involved in the protection and assembly of methylmalonyl-CoA mutase	Dechloromonas aromatica RCB Gene: Daro_4005: auxiliary metallochaperone, involved in the protection and assembly of methylmalonyl-CoA mutase	Thauera sp. MZ1T Gene: Tmz1t_3485: auxiliary metallochaperone, involved in the protection and assembly of methylmalonyl-CoA mutase	Chromobacterium violaceum ATCC 12472	Laribacter hongkongensis HLHK9	Neisseria meningitidis MC58	auxiliary metallochaperone, involved in the protection and assembly of methylmalonyl-CoA mutase
pccB	Methylobacillus flagellatus KT	Methylophilales bacterium HTCC2181	Methylotenera mobilis JLW8	Nitrosomonas europaea ATCC 19718	Nitrosospira multiformis ATCC 25196	Thiobacillus denitrificans	Azoarcus sp. EbN1 Gene: ebA3742: Propionyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.3)	Dechloromonas aromatica RCB Gene: Daro_4004: Propionyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.3)	Thauera sp. MZ1T Gene: Tmz1t_3484: Propionyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.3)	Chromobacterium violaceum ATCC 12472	Laribacter hongkongensis HLHK9	Neisseria meningitidis MC58	Propionyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.3)
pccA	Methylobacillus flagellatus KT	Methylophilales bacterium HTCC2181	Methylotenera mobilis JLW8	Nitrosomonas europaea ATCC 19718	Nitrosospira multiformis ATCC 25196	Thiobacillus denitrificans	2 Azoarcus sp. EbN1 Gene: ebA3743: Propionyl-CoA carboxylase, alpha subunit Gene: ebA5667: Propionyl-CoA carboxylase, alpha subunit	Dechloromonas aromatica RCB Gene: Daro_4003: Propionyl-CoA carboxylase, alpha subunit	Thauera sp. MZ1T Gene: Tmz1t_3483: Propionyl-CoA carboxylase, alpha subunit	Chromobacterium violaceum ATCC 12472	Laribacter hongkongensis HLHK9	Neisseria meningitidis MC58	Propionyl-CoA carboxylase, alpha subunit

CRON 6.
Daro_4011	Methylobacillus flagellatus KT	Methylophilales bacterium HTCC2181	Methylotenera mobilis JLW8	Nitrosomonas europaea ATCC 19718	Nitrosospira multiformis ATCC 25196	Thiobacillus denitrificans	Azoarcus sp. EbN1	* Dechloromonas aromatica RCB Site: position = -26 score = 4.66108 sequence = TAATTATTAATTAGGGAGGA Site: position = -33 score = 4.29429 sequence = TTTACGGTAATTATTAATTA Gene: Daro_4011: Putative membrane protein, clustering with ActP	Thauera sp. MZ1T Gene: Tmz1t_3490: Putative membrane protein, clustering with ActP	Chromobacterium violaceum ATCC 12472	Laribacter hongkongensis HLHK9 Gene: LHK_01261: Putative membrane protein, clustering with ActP	Neisseria meningitidis MC58	Putative membrane protein, clustering with ActP
actP	Methylobacillus flagellatus KT	Methylophilales bacterium HTCC2181	Methylotenera mobilis JLW8	Nitrosomonas europaea ATCC 19718	Nitrosospira multiformis ATCC 25196	Thiobacillus denitrificans	Azoarcus sp. EbN1 Gene: ebA3695: Acetate permease ActP (cation/acetate symporter)	Dechloromonas aromatica RCB Gene: Daro_4010: Acetate permease ActP (cation/acetate symporter)	Thauera sp. MZ1T Gene: Tmz1t_3489: Acetate permease ActP (cation/acetate symporter)	Chromobacterium violaceum ATCC 12472	Laribacter hongkongensis HLHK9 Gene: LHK_01260: Acetate permease ActP (cation/acetate symporter)	Neisseria meningitidis MC58	Acetate permease ActP (cation/acetate symporter)

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog MlnR - Various betaproteobacteria

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --