Regulog NanR - Bifidobacteriaceae

Properties
Regulator type:	Transcription factor
Regulator family:	GntR/Others
Regulation mode:	repressor
Biological process:	Sialic acid utilization
Effector:	Sialic acid
Phylum:	Actinobacteria
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 11 sites [see more]

Member of regulog collections

By taxonomy - Bifidobacteriaceae
By TF family - GntR/Others
By effector - Sialic acid
By pathway - Sialic acid utilization

Statistics of regulated genes
Genome	Genes	Operons
Bifidobacterium longum subsp. infantis ATCC 15697	9	3
Bifidobacterium adolescentis ATCC 15703
Bifidobacterium angulatum DSM 20098
Bifidobacterium animalis subsp. lactis AD011
Bifidobacterium bifidum NCIMB 41171
Bifidobacterium breve DSM 20213	8	2
Bifidobacterium dentium Bd1
Bifidobacterium gallicum DSM 20093	6	2
Bifidobacterium longum NCC2705
Gardnerella vaginalis 409-05

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes											Function

CRON 1.
nanH	* Bifidobacterium longum subsp. infantis ATCC 15697 Site: position = -200 score = 6.50645 sequence = ATAAGACGTCTGACGTCTTAT Site: position = -102 score = 5.00828 sequence = ATCAGACGTCTGATGTTTCCC Gene: Blon_0646: Sialidase (EC 3.2.1.18)	Bifidobacterium adolescentis ATCC 15703	Bifidobacterium angulatum DSM 20098	Bifidobacterium animalis subsp. lactis AD011	Bifidobacterium bifidum NCIMB 41171	Bifidobacterium breve DSM 20213 Gene: BIFBRE_01961: Sialidase (EC 3.2.1.18)	Bifidobacterium dentium Bd1	Bifidobacterium gallicum DSM 20093	Bifidobacterium longum NCC2705	Gardnerella vaginalis 409-05	Sialidase (EC 3.2.1.18)

CRON 2.
SSF51658	* Bifidobacterium longum subsp. infantis ATCC 15697 Site: position = -73 score = 5.23675 sequence = GATATACATCAGATGTCTGAT Site: position = -66 score = 5.42942 sequence = ATCAGATGTCTGATGTATAAT Gene: Blon_0643: Xylose isomerase-like, TIM barrel domain	Bifidobacterium adolescentis ATCC 15703	Bifidobacterium angulatum DSM 20098	Bifidobacterium animalis subsp. lactis AD011	Bifidobacterium bifidum NCIMB 41171	* Bifidobacterium breve DSM 20213 Site: position = -36 score = 6.25217 sequence = ATTGGACATCAGACGTCTGAT Gene: BIFBRE_01949: Xylose isomerase-like, TIM barrel domain	Bifidobacterium dentium Bd1	* Bifidobacterium gallicum DSM 20093 Site: position = -220 score = 6.07793 sequence = GTAAGACATCAGATGTCTGAT Gene: BIFGAL_00397: Xylose isomerase-like, TIM barrel domain	Bifidobacterium longum NCC2705	Gardnerella vaginalis 409-05	Xylose isomerase-like, TIM barrel domain
nanK	Bifidobacterium longum subsp. infantis ATCC 15697 Gene: Blon_0644: N-acetylmannosamine kinase (EC 2.7.1.60)	Bifidobacterium adolescentis ATCC 15703	Bifidobacterium angulatum DSM 20098	Bifidobacterium animalis subsp. lactis AD011	Bifidobacterium bifidum NCIMB 41171	Bifidobacterium breve DSM 20213 Gene: BIFBRE_01950: N-acetylmannosamine kinase (EC 2.7.1.60)	Bifidobacterium dentium Bd1	Bifidobacterium gallicum DSM 20093	Bifidobacterium longum NCC2705	Gardnerella vaginalis 409-05	N-acetylmannosamine kinase (EC 2.7.1.60)
nanE	Bifidobacterium longum subsp. infantis ATCC 15697 Gene: Blon_0645: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)	Bifidobacterium adolescentis ATCC 15703	Bifidobacterium angulatum DSM 20098	Bifidobacterium animalis subsp. lactis AD011	Bifidobacterium bifidum NCIMB 41171	Bifidobacterium breve DSM 20213	Bifidobacterium dentium Bd1	Bifidobacterium gallicum DSM 20093	Bifidobacterium longum NCC2705	Gardnerella vaginalis 409-05	N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)

CRON 3.
nanB	* Bifidobacterium longum subsp. infantis ATCC 15697 Site: position = -250 score = 4.89816 sequence = GGGAAACATCAGACGTCTGAT Site: position = -152 score = 6.58557 sequence = ATAAGACGTCAGACGTCTTAT Gene: Blon_0647: Predicted sialic acid ABC transporter, solute binding component	Bifidobacterium adolescentis ATCC 15703	Bifidobacterium angulatum DSM 20098	Bifidobacterium animalis subsp. lactis AD011	Bifidobacterium bifidum NCIMB 41171	* Bifidobacterium breve DSM 20213 Site: position = -149 score = 5.51163 sequence = ATAAGTTGTCTGATGTCTTAA Site: position = -42 score = 5.83195 sequence = ATCAGACATCAGATGTCATAT Gene: BIFBRE_01954: Predicted sialic acid ABC transporter, solute binding component	Bifidobacterium dentium Bd1	* Bifidobacterium gallicum DSM 20093 Site: position = -12 score = 6.18943 sequence = ATCAGACATCTGATGTCTTAC Gene: BIFGAL_00396: Predicted sialic acid ABC transporter, solute binding component	Bifidobacterium longum NCC2705	Gardnerella vaginalis 409-05	Predicted sialic acid ABC transporter, solute binding component
nanC	Bifidobacterium longum subsp. infantis ATCC 15697 Gene: Blon_0648: Predicted sialic acid ABC transporter, permease component	Bifidobacterium adolescentis ATCC 15703	Bifidobacterium angulatum DSM 20098	Bifidobacterium animalis subsp. lactis AD011	Bifidobacterium bifidum NCIMB 41171	Bifidobacterium breve DSM 20213 Gene: BIFBRE_01955: Predicted sialic acid ABC transporter, permease component	Bifidobacterium dentium Bd1	Bifidobacterium gallicum DSM 20093 Gene: BIFGAL_00395: Predicted sialic acid ABC transporter, permease component	Bifidobacterium longum NCC2705	Gardnerella vaginalis 409-05	Predicted sialic acid ABC transporter, permease component
nanD	Bifidobacterium longum subsp. infantis ATCC 15697 Gene: Blon_0649: Predicted sialic acid ABC transporter, permease component and ATP-binding component	Bifidobacterium adolescentis ATCC 15703	Bifidobacterium angulatum DSM 20098	Bifidobacterium animalis subsp. lactis AD011	Bifidobacterium bifidum NCIMB 41171	Bifidobacterium breve DSM 20213 Gene: BIFBRE_01956: Predicted sialic acid ABC transporter, permease component and ATP-binding component	Bifidobacterium dentium Bd1	Bifidobacterium gallicum DSM 20093 Gene: BIFGAL_00394: Predicted sialic acid ABC transporter, permease component and ATP-binding component	Bifidobacterium longum NCC2705	Gardnerella vaginalis 409-05	Predicted sialic acid ABC transporter, permease component and ATP-binding component
nanF	Bifidobacterium longum subsp. infantis ATCC 15697 Gene: Blon_0650: Predicted sialic acid ABC transporter, ATP binding component	Bifidobacterium adolescentis ATCC 15703	Bifidobacterium angulatum DSM 20098	Bifidobacterium animalis subsp. lactis AD011	Bifidobacterium bifidum NCIMB 41171	Bifidobacterium breve DSM 20213 Gene: BIFBRE_01957: Predicted sialic acid ABC transporter, ATP binding component	Bifidobacterium dentium Bd1	Bifidobacterium gallicum DSM 20093 Gene: BIFGAL_00393: Predicted sialic acid ABC transporter, ATP binding component	Bifidobacterium longum NCC2705	Gardnerella vaginalis 409-05	Predicted sialic acid ABC transporter, ATP binding component
nanA	Bifidobacterium longum subsp. infantis ATCC 15697 Gene: Blon_0651: N-acetylneuraminate lyase (EC 2.5.1.56)	Bifidobacterium adolescentis ATCC 15703	Bifidobacterium angulatum DSM 20098	Bifidobacterium animalis subsp. lactis AD011	Bifidobacterium bifidum NCIMB 41171	Bifidobacterium breve DSM 20213 Gene: BIFBRE_01958: N-acetylneuraminate lyase (EC 2.5.1.56)	Bifidobacterium dentium Bd1	Bifidobacterium gallicum DSM 20093 Gene: BIFGAL_00392: N-acetylneuraminate lyase (EC 2.5.1.56)	Bifidobacterium longum NCC2705	Gardnerella vaginalis 409-05	N-acetylneuraminate lyase (EC 2.5.1.56)
nagB2	Bifidobacterium longum subsp. infantis ATCC 15697	Bifidobacterium adolescentis ATCC 15703	Bifidobacterium angulatum DSM 20098	Bifidobacterium animalis subsp. lactis AD011	Bifidobacterium bifidum NCIMB 41171	Bifidobacterium breve DSM 20213 Gene: BIFBRE_01959: Glucosamine-6-phosphate deaminase (EC 3.5.99.6)	Bifidobacterium dentium Bd1	Bifidobacterium gallicum DSM 20093	Bifidobacterium longum NCC2705	Gardnerella vaginalis 409-05	Glucosamine-6-phosphate deaminase (EC 3.5.99.6)

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

Export
	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog NanR - Bifidobacteriaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --