Regulog DasR - Frankineae/Propionibacterineae/Pseudonocardiaceae
| Regulator type: | Transcription factor |
| Regulator family: | GntR/Others |
| Regulation mode: | repressor |
| Biological process: | N-acetylglucosamine utilization |
| Effector: | Glucosamine-6-phosphate |
| Phylum: | Actinobacteria |
| Visualization: | |
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Allows to visualize regulog content in the context of metabolic pathways |
Member of regulog collections
- By taxonomy - Frankineae/Propionibacterineae/Pseudonocardiaceae
- By trascription factor - DasR
- By TF family - GntR/Others
- By effector - Glucosamine-6-phosphate
- By pathway - N-acetylglucosamine utilization
| Genome | Genes | Operons |
|---|---|---|
| Acidothermus cellulolyticus 11B | 14 | 9 |
| Frankia sp. CcI3 | ||
| Frankia sp. EAN1pec | ||
| Nakamurella multipartita DSM 44233 | 5 | 2 |
| Nocardioides sp. JS614 | 1 | 1 |
| Propionibacterium acnes KPA171202 | 4 | 3 |
| Actinosynnema mirum DSM 43827 | 25 | 15 |
| Saccharomonospora viridis DSM 43017 | 9 | 5 |
| Saccharopolyspora erythraea NRRL 2338 | 18 | 13 |
| Genes | Function | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| CRON 1. | ||||||||||
| dasR |
*
Acidothermus cellulolyticus 11B Site: position = -312 score = 4.78441 sequence = GTTGGCATAGACCACC Site: position = -334 score = 5.68801 sequence = ATTGGTTTAGACCAAT Gene: Acel_0551: Transcriptional regulator of N-Acetylglucosamine utilization, GntR family |
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Nakamurella multipartita DSM 44233 Site: position = -47 score = 4.91924 sequence = ATTGGCGTAGACCATT Gene: Namu_0953: Transcriptional regulator of N-Acetylglucosamine utilization, GntR family |
Gene: Noca_3959: Transcriptional regulator of N-Acetylglucosamine utilization, GntR family |
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Propionibacterium acnes KPA171202 Site: position = -140 score = 4.9451 sequence = GGTGGTATGGACCACT Gene: PPA0676: Transcriptional regulator of N-Acetylglucosamine utilization, GntR family |
*
Actinosynnema mirum DSM 43827 Site: position = -173 score = 5.58276 sequence = AGTGGTGTAGACCAAT Gene: Amir_0404: Transcriptional regulator of N-Acetylglucosamine utilization, GntR family |
*
Saccharomonospora viridis DSM 43017 Site: position = -94 score = 5.12218 sequence = ACCGGTCTAGACCATT Gene: Svir_34690: Transcriptional regulator of N-Acetylglucosamine utilization, GntR family |
Gene: SACE_0500: Transcriptional regulator of N-Acetylglucosamine utilization, GntR family |
Transcriptional regulator of N-Acetylglucosamine utilization, GntR family |
| nagF |
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*2
Propionibacterium acnes KPA171202 Site: position = -89 score = 4.84426 sequence = AGTTGTCTGGACCACT Gene: PPA0678: PTS system N-acetylglucosamine-specific EIIB component Gene: PPA0677: PTS system N-acetylglucosamine-specific EIIB component |
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Actinosynnema mirum DSM 43827 Site: position = -126 score = 5.08587 sequence = TCCGGTCTAGACCAGT Gene: Amir_5258: PTS system N-acetylglucosamine-specific EIIB component |
*
Saccharomonospora viridis DSM 43017 Site: position = -121 score = 5.1515 sequence = TCCGGTCTAGACCACT Gene: Svir_15400: PTS system N-acetylglucosamine-specific EIIB component |
*
Saccharopolyspora erythraea NRRL 2338 Site: position = -159 score = 4.71205 sequence = TCCGGTCTAAACCAGT Gene: SACE_2061: PTS system N-acetylglucosamine-specific EIIB component |
PTS system N-acetylglucosamine-specific EIIB component |
| nagG |
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Gene: PPA0679: PTS system N-acetylglucosamine-specific EIIA component |
Gene: Amir_5257: PTS system N-acetylglucosamine-specific EIIA component |
Gene: Svir_15410: PTS system N-acetylglucosamine-specific EIIA component |
Gene: SACE_2062: PTS system N-acetylglucosamine-specific EIIA component |
PTS system N-acetylglucosamine-specific EIIA component |
| CRON 2. | ||||||||||
| glcI |
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Actinosynnema mirum DSM 43827 Site: position = -167 score = 4.57896 sequence = AGAGGTCTAGTCCACC Gene: Amir_4031: Glucan endo-1,3-beta-glucosidase |
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Glucan endo-1,3-beta-glucosidase |
| CRON 3. | ||||||||||
| chb |
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*2
Actinosynnema mirum DSM 43827 Site: position = -157 score = 5.05 sequence = TATGGTCTAGACCAAG Gene: Amir_5334: Chitin binding protein Site: position = -122 score = 4.67269 sequence = TATGGTCTAGACCGGC Gene: Amir_5107: Chitin binding protein |
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Saccharopolyspora erythraea NRRL 2338 Site: position = -143 score = 4.70486 sequence = GTTGGACTGGACCAAA Site: position = -121 score = 4.6612 sequence = CATGGTCTGGACCAAA Gene: SACE_0110: Chitin binding protein |
Chitin binding protein |
| Amir_5333 |
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Gene: Amir_5333: putative lipoprotein |
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putative lipoprotein |
| CRON 4. | ||||||||||
| Acel_1459 |
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Acidothermus cellulolyticus 11B Site: position = -142 score = 4.30004 sequence = CCTGGTCTAGTCCTCT Gene: Acel_1459: Exochitinase 1 precursor (EC 3.2.1.14) |
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Exochitinase 1 precursor (EC 3.2.1.14) |
| chiA |
Gene: Acel_1458: Chitinase A precursor (EC 3.2.1.14) |
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*
Actinosynnema mirum DSM 43827 Site: position = -80 score = 5.4379 sequence = ATTGGTCTAGTCCACT Gene: Amir_1220: Chitinase A precursor (EC 3.2.1.14) |
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*
Saccharopolyspora erythraea NRRL 2338 Site: position = -71 score = 5.08886 sequence = AGTGGTCTAGTCCATT Gene: SACE_5394: Chitinase A precursor (EC 3.2.1.14) |
Chitinase A precursor (EC 3.2.1.14) |
| CRON 5. | ||||||||||
| dasA |
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Acidothermus cellulolyticus 11B Site: position = -64 score = 5.68801 sequence = ATTGGTCTAAACCAAT Site: position = -86 score = 4.78441 sequence = GGTGGTCTATGCCAAC Gene: Acel_0552: sugar transporter sugar binding protein |
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Actinosynnema mirum DSM 43827 Site: position = -87 score = 5.58276 sequence = ATTGGTCTACACCACT Gene: Amir_0403: sugar transporter sugar binding protein |
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sugar transporter sugar binding protein |
| dasB |
Gene: Acel_0553: sugar transporter integral membrane protein |
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Gene: Amir_0402: sugar transporter integral membrane protein |
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sugar transporter integral membrane protein |
| dasC |
Gene: Acel_0554: sugar transporter inner membrane protein |
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Gene: Amir_0401: sugar transporter inner membrane protein |
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sugar transporter inner membrane protein |
| nagK |
*2
Acidothermus cellulolyticus 11B Gene: Acel_0555: N-acetylglucosamine kinase of eukaryotic type (EC 2.7.1.59) Site: position = -94 score = 4.86563 sequence = ATCGGTACAGACCACT Gene: Acel_1854: N-acetylglucosamine kinase of eukaryotic type (EC 2.7.1.59) |
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Gene: PPA1986: N-acetylglucosamine kinase of eukaryotic type (EC 2.7.1.59) |
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N-acetylglucosamine kinase of eukaryotic type (EC 2.7.1.59) |
| nagB2 |
Gene: Acel_0556: Glucosamine-6-phosphate deaminase [isomerizing], alternative (EC 3.5.99.6) |
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Glucosamine-6-phosphate deaminase [isomerizing], alternative (EC 3.5.99.6) |
| CRON 6. | ||||||||||
| chiC |
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*
Actinosynnema mirum DSM 43827 Site: position = -80 score = 4.64055 sequence = AGTGGTCTAGACCTTG Site: position = -57 score = 4.87423 sequence = AGTGGTCTGAACCACA Gene: Amir_6206: Chitinase (EC 3.2.1.14) |
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*2
Saccharopolyspora erythraea NRRL 2338 Gene: SACE_6557: Chitinase (EC 3.2.1.14) Site: position = -172 score = 4.63937 sequence = GGTGGTCTAGACCTTA Gene: SACE_6558: Chitinase (EC 3.2.1.14) |
Chitinase (EC 3.2.1.14) |
| CRON 7. | ||||||||||
| COG3179 |
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*
Actinosynnema mirum DSM 43827 Site: position = -75 score = 5.51713 sequence = ACTGGTGTAGACCAAT Gene: Amir_5336: Predicted chitinase |
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Predicted chitinase |
| CRON 8. | ||||||||||
| glmS |
Gene: Acel_0344: Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16) |
Gene: Francci3_0617: Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16) |
Gene: Franean1_6015: Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16) |
Gene: Namu_1187: Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16) |
2
Nocardioides sp. JS614 Gene: Noca_4602: Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16) Gene: Noca_0896: Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16) |
Gene: PPA1794: Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16) |
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Actinosynnema mirum DSM 43827 Site: position = -91 score = 5.47353 sequence = ATTGGTCTACACCAAA Gene: Amir_6558: Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16) |
Gene: Svir_04560: Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16) |
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Saccharopolyspora erythraea NRRL 2338 Site: position = -38 score = 4.53167 sequence = GGAGGTATGGACCAAT Gene: SACE_6768: Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16) |
Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16) |
| CRON 9. | ||||||||||
| nagB2 |
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Actinosynnema mirum DSM 43827 Site: position = -63 score = 5.32867 sequence = ATTGGTCTAGACCTAA Gene: Amir_0400: Glucosamine-6-phosphate deaminase [isomerizing], alternative (EC 3.5.99.6) |
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Saccharomonospora viridis DSM 43017 Site: position = -31 score = 5.12218 sequence = AATGGTCTAGACCGGT Gene: Svir_34700: Glucosamine-6-phosphate deaminase [isomerizing], alternative (EC 3.5.99.6) |
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Saccharopolyspora erythraea NRRL 2338 Site: position = -34 score = 4.92397 sequence = ATTGGTCTAGACCTGG Gene: SACE_0498: Glucosamine-6-phosphate deaminase [isomerizing], alternative (EC 3.5.99.6) |
Glucosamine-6-phosphate deaminase [isomerizing], alternative (EC 3.5.99.6) |
| nagK |
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Gene: Amir_0391: N-acetylglucosamine kinase of eukaryotic type (EC 2.7.1.59) |
Gene: Svir_34710: N-acetylglucosamine kinase of eukaryotic type (EC 2.7.1.59) |
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N-acetylglucosamine kinase of eukaryotic type (EC 2.7.1.59) |
| CRON 10. | ||||||||||
| chiB |
*2
Acidothermus cellulolyticus 11B Site: position = -43 score = 5.53685 sequence = ATTGGTCTAGGCCACT Site: position = -65 score = 5.02447 sequence = ATTGGACTAGTCCAAT Gene: Acel_1460: Chitinase (EC 3.2.1.14) Site: position = -80 score = 4.80997 sequence = ATTGGTCTTGACCTAT Site: position = -66 score = 5.6421 sequence = ATTGGTCTAGGCCAAT Gene: Acel_0603: Chitinase (EC 3.2.1.14) |
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Chitinase (EC 3.2.1.14) |
| CRON 11. | ||||||||||
| nagE |
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*
Nakamurella multipartita DSM 44233 Site: position = -169 score = 5.35968 sequence = ATTGGTCTATGCCAAT Site: position = -140 score = 5.5444 sequence = GTTGGTCTATACCAAT Gene: Namu_0958: PTS system, N-acetylglucosamine-specific IIB component (EC 2.7.1.69) / PTS system, N-acetylglucosamine-specific IIC component (EC 2.7.1.69) |
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Propionibacterium acnes KPA171202 Site: position = -51 score = 4.9451 sequence = AGTGGTCCATACCACC Gene: PPA0675: PTS system, N-acetylglucosamine-specific IIB component (EC 2.7.1.69) / PTS system, N-acetylglucosamine-specific IIC component (EC 2.7.1.69) |
Gene: Amir_5260: PTS system, N-acetylglucosamine-specific IIB component (EC 2.7.1.69) / PTS system, N-acetylglucosamine-specific IIC component (EC 2.7.1.69) |
Gene: Svir_15380: PTS system, N-acetylglucosamine-specific IIB component (EC 2.7.1.69) / PTS system, N-acetylglucosamine-specific IIC component (EC 2.7.1.69) |
Gene: SACE_2059: PTS system, N-acetylglucosamine-specific IIB component (EC 2.7.1.69) / PTS system, N-acetylglucosamine-specific IIC component (EC 2.7.1.69) |
PTS system, N-acetylglucosamine-specific IIB component (EC 2.7.1.69) / PTS system, N-acetylglucosamine-specific IIC component (EC 2.7.1.69) |
| Namu_0959 |
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Gene: Namu_0959: hypothetical protein |
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hypothetical protein |
| nagB |
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Gene: Namu_0960: Glucosamine-6-phosphate deaminase (EC 3.5.99.6) |
Gene: Noca_4483: Glucosamine-6-phosphate deaminase (EC 3.5.99.6) |
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Glucosamine-6-phosphate deaminase (EC 3.5.99.6) |
| nagA |
*
Acidothermus cellulolyticus 11B Site: position = -183 score = 5.10951 sequence = TATGGTCTGGACCAAT Site: position = -141 score = 5.22342 sequence = ATTGGTCTAGTCCACA Gene: Acel_0557: N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25) |
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Gene: Franean1_4198: N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25) |
Gene: Namu_0961: N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25) |
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Gene: PPA0484: N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25) |
Gene: Amir_6924: N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25) |
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Saccharomonospora viridis DSM 43017 Site: position = -21 score = 5.28768 sequence = TCTGGTCTGGACCAAT Gene: Svir_38290: N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25) |
Gene: SACE_7184: N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25) |
N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25) |
| dasR2 |
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Actinosynnema mirum DSM 43827 Site: position = -63 score = 5.08587 sequence = ACTGGTCTAGACCGGA Gene: Amir_5259: Transcriptional regulator of N-Acetylglucosamine utilization, GntR family |
*
Saccharomonospora viridis DSM 43017 Site: position = -60 score = 5.1515 sequence = AGTGGTCTAGACCGGA Gene: Svir_15390: Transcriptional regulator of N-Acetylglucosamine utilization, GntR family |
*
Saccharopolyspora erythraea NRRL 2338 Site: position = -124 score = 4.71205 sequence = ACTGGTTTAGACCGGA Gene: SACE_2060: Transcriptional regulator of N-Acetylglucosamine utilization, GntR family |
Transcriptional regulator of N-Acetylglucosamine utilization, GntR family |
| ptsH |
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Gene: Amir_5261: Phosphotransferase system, phosphocarrier protein HPr |
Gene: Svir_15370: Phosphotransferase system, phosphocarrier protein HPr |
Gene: SACE_2058: Phosphotransferase system, phosphocarrier protein HPr |
Phosphotransferase system, phosphocarrier protein HPr |
| nagK2 |
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Actinosynnema mirum DSM 43827 Site: position = -63 score = 5.3311 sequence = CTTGGTATAGACCAAT Gene: Amir_6923: Predicted N-acetylglucosamine kinase, glucokinase-like (EC 2.7.1.59) |
Gene: Svir_16630: Predicted N-acetylglucosamine kinase, glucokinase-like (EC 2.7.1.59) |
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Saccharopolyspora erythraea NRRL 2338 Site: position = -43 score = 5.34775 sequence = GTTGGTGTAGACCACT Gene: SACE_7183: Predicted N-acetylglucosamine kinase, glucokinase-like (EC 2.7.1.59) |
Predicted N-acetylglucosamine kinase, glucokinase-like (EC 2.7.1.59) |
| CRON 12. | ||||||||||
| nagT |
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Actinosynnema mirum DSM 43827 Site: position = -100 score = 4.92278 sequence = TCTGGTCTAGACCTAC Gene: Amir_0446: N-Acetyl-D-glucosamine ABC transport system, sugar-binding protein |
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N-Acetyl-D-glucosamine ABC transport system, sugar-binding protein |
| nagU |
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Gene: Amir_0447: N-Acetyl-D-glucosamine ABC transport system, permease protein 1 |
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N-Acetyl-D-glucosamine ABC transport system, permease protein 1 |
| nagV |
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Gene: Amir_0448: N-Acetyl-D-glucosamine ABC transport system, permease protein 2 |
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N-Acetyl-D-glucosamine ABC transport system, permease protein 2 |
| hex |
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Acidothermus cellulolyticus 11B Site: position = -61 score = 4.67543 sequence = AAAGGTCTAGACCTAT Gene: Acel_0128: Beta-hexosaminidase (EC 3.2.1.52) |
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Gene: Noca_4486: Beta-hexosaminidase (EC 3.2.1.52) |
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*2
Actinosynnema mirum DSM 43827 Site: position = -41 score = 4.357 sequence = ATTGGTCCAGACCTTG Gene: Amir_1091: Beta-hexosaminidase (EC 3.2.1.52) Gene: Amir_0449: Beta-hexosaminidase (EC 3.2.1.52) |
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Saccharopolyspora erythraea NRRL 2338 Site: position = -51 score = 4.69721 sequence = TTTGGTCTATACCTTT Gene: SACE_3851: Beta-hexosaminidase (EC 3.2.1.52) |
Beta-hexosaminidase (EC 3.2.1.52) |
| CRON 13. | ||||||||||
| chiB |
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Saccharopolyspora erythraea NRRL 2338 Site: position = -104 score = 4.41651 sequence = ATTGGACCGGACCATT Site: position = -77 score = 4.70884 sequence = GGTGGTCCAGTCCACT Gene: SACE_2232: Chitinase (EC 3.2.1.14) |
Chitinase (EC 3.2.1.14) |
| CRON 14. | ||||||||||
| ptsI |
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Saccharopolyspora erythraea NRRL 2338 Site: position = -13 score = 4.70096 sequence = TATGGTCTAGACCATG Gene: SACE_7368: Phosphoenolpyruvate-protein phosphotransferase of PTS system (EC 2.7.3.9) |
Phosphoenolpyruvate-protein phosphotransferase of PTS system (EC 2.7.3.9) |
| CRON 15. | ||||||||||
| Noca_0732 |
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Nocardioides sp. JS614 Site: position = -27 score = 5.13726 sequence = GCTGGTCTAGACCTAT Gene: Noca_0732: N-acetylmuramoyl-L-alanine amidase, major autolysin [EC:3.5.1.28] [KO:K01448] |
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N-acetylmuramoyl-L-alanine amidase, major autolysin [EC:3.5.1.28] [KO:K01448] |
| CRON 16. | ||||||||||
| chi |
*
Acidothermus cellulolyticus 11B Site: position = -174 score = 5.30814 sequence = GTTGGTCTAGTCCAAT Gene: Acel_2033: Chitinase (EC 3.2.1.14) |
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*3
Saccharopolyspora erythraea NRRL 2338 Gene: SACE_5287: Chitinase (EC 3.2.1.14) Site: position = -68 score = 5.28768 sequence = ACTGGTCTGGACCAAA Gene: SACE_3887: Chitinase (EC 3.2.1.14) Site: position = -99 score = 4.67653 sequence = GGTGGTACAAACCAAT Gene: SACE_1076: Chitinase (EC 3.2.1.14) |
Chitinase (EC 3.2.1.14) |
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
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Regulatory Sites | [ FASTA format ] | DOWNLOAD |