Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of DasR in Actinosynnema mirum DSM 43827

Properties
Regulator type: Transcription factor
TF locus tag: Amir_0404, Amir_5259
Regulator family: GntR/Others
Regulation mode: repressor
Biological process: N-acetylglucosamine utilization
Effector: Glucosamine-6-phosphate
Regulog: DasR - Frankineae/Propionibacterineae/Pseudonocardiaceae
Statistics of regulated genes:
- Genes 25
- Operons 15
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 57 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -63
Score: 5.3
Sequence: CTTGGTATAGACCAAT
Locus tag: Amir_6923
Name: nagK2
Funciton: Predicted N-acetylglucosamine kinase, glucokinase-like (EC 2.7.1.59)
Locus tag: Amir_6924
Name: nagA
Funciton: N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25)
nagK2
Predicted N-acetylglucosamine kinase, glucokinase-like (EC 2.7.1.59)
nagA
N-acetylglucosamine-6-phosphate deacetylase (EC 3.5.1.25)

Position: -173
Score: 5.6
Sequence: AGTGGTGTAGACCAAT
Locus tag: Amir_0404
Name: dasR
Funciton: Transcriptional regulator of N-Acetylglucosamine utilization, GntR family
dasR
Transcriptional regulator of N-Acetylglucosamine utilization, GntR family

Position: -87
Score: 5.6
Sequence: ATTGGTCTACACCACT
Locus tag: Amir_0403
Name: dasA
Funciton: sugar transporter sugar binding protein
Locus tag: Amir_0402
Name: dasB
Funciton: sugar transporter integral membrane protein
Locus tag: Amir_0401
Name: dasC
Funciton: sugar transporter inner membrane protein
dasA
sugar transporter sugar binding protein
dasB
sugar transporter integral membrane protein
dasC
sugar transporter inner membrane protein

Position: -122
Score: 4.7
Sequence: TATGGTCTAGACCGGC
Locus tag: Amir_5107
Name: chb
Funciton: Chitin binding protein
chb
Chitin binding protein

Position: -80
Score: 4.6
Sequence: AGTGGTCTAGACCTTG
Position: -57
Score: 4.9
Sequence: AGTGGTCTGAACCACA
Locus tag: Amir_6206
Name: chiC
Funciton: Chitinase (EC 3.2.1.14)
chiC
Chitinase (EC 3.2.1.14)

Position: -100
Score: 4.9
Sequence: TCTGGTCTAGACCTAC
Locus tag: Amir_0446
Name: nagT
Funciton: N-Acetyl-D-glucosamine ABC transport system, sugar-binding protein
Locus tag: Amir_0447
Name: nagU
Funciton: N-Acetyl-D-glucosamine ABC transport system, permease protein 1
Locus tag: Amir_0448
Name: nagV
Funciton: N-Acetyl-D-glucosamine ABC transport system, permease protein 2
Locus tag: Amir_0449
Name: hex
Funciton: Beta-hexosaminidase (EC 3.2.1.52)
nagT
N-Acetyl-D-glucosamine ABC transport system, sugar-binding protein
nagU
N-Acetyl-D-glucosamine ABC transport system, permease protein 1
nagV
N-Acetyl-D-glucosamine ABC transport system, permease protein 2
hex
Beta-hexosaminidase (EC 3.2.1.52)

Position: -157
Score: 5.1
Sequence: TATGGTCTAGACCAAG
Locus tag: Amir_5334
Name: chb
Funciton: Chitin binding protein
Locus tag: Amir_5333
Name: null
Funciton: putative lipoprotein
chb
Chitin binding protein
putative lipoprotein

Position: -126
Score: 5.1
Sequence: TCCGGTCTAGACCAGT
Locus tag: Amir_5258
Name: nagF
Funciton: PTS system N-acetylglucosamine-specific EIIB component
Locus tag: Amir_5257
Name: nagG
Funciton: PTS system N-acetylglucosamine-specific EIIA component
nagF
PTS system N-acetylglucosamine-specific EIIB component
nagG
PTS system N-acetylglucosamine-specific EIIA component

Position: -63
Score: 5.3
Sequence: ATTGGTCTAGACCTAA
Locus tag: Amir_0400
Name: nagB2
Funciton: Glucosamine-6-phosphate deaminase [isomerizing], alternative (EC 3.5.99.6)
nagB2
Glucosamine-6-phosphate deaminase [isomerizing], alternative (EC 3.5.99.6)

Position: -80
Score: 5.4
Sequence: ATTGGTCTAGTCCACT
Locus tag: Amir_1220
Name: chiA
Funciton: Chitinase A precursor (EC 3.2.1.14)
chiA
Chitinase A precursor (EC 3.2.1.14)

Position: -167
Score: 4.6
Sequence: AGAGGTCTAGTCCACC
Locus tag: Amir_4031
Name: glcI
Funciton: Glucan endo-1,3-beta-glucosidase
glcI
Glucan endo-1,3-beta-glucosidase

Position: -91
Score: 5.5
Sequence: ATTGGTCTACACCAAA
Locus tag: Amir_6558
Name: glmS
Funciton: Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16)
glmS
Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] (EC 2.6.1.16)

Position: -75
Score: 5.5
Sequence: ACTGGTGTAGACCAAT
Locus tag: Amir_5336
Name: COG3179
Funciton: Predicted chitinase
COG3179
Predicted chitinase

Position: -41
Score: 4.4
Sequence: ATTGGTCCAGACCTTG
Locus tag: Amir_1091
Name: hex
Funciton: Beta-hexosaminidase (EC 3.2.1.52)
hex
Beta-hexosaminidase (EC 3.2.1.52)

Position: -63
Score: 5.1
Sequence: ACTGGTCTAGACCGGA
Locus tag: Amir_5259
Name: dasR2
Funciton: Transcriptional regulator of N-Acetylglucosamine utilization, GntR family
Locus tag: Amir_5260
Name: nagE
Funciton: PTS system, N-acetylglucosamine-specific IIB component (EC 2.7.1.69) / PTS system, N-acetylglucosamine-specific IIC component (EC 2.7.1.69)
Locus tag: Amir_5261
Name: ptsH
Funciton: Phosphotransferase system, phosphocarrier protein HPr
dasR2
Transcriptional regulator of N-Acetylglucosamine utilization, GntR family
nagE
PTS system, N-acetylglucosamine-specific IIB component (EC 2.7.1.69) / PTS system, N-acetylglucosamine-specific IIC component (EC 2.7.1.69)
ptsH
Phosphotransferase system, phosphocarrier protein HPr
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