Regulog UxuR - Pasteurellales

Properties
Regulator type:	Transcription factor
Regulator family:	GntR/Others
Regulation mode:	repressor
Biological process:	Glucuronate utilization
Effector:	Glucuronate
Phylum:	Proteobacteria
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 19 sites [see more]

Member of regulog collections

By trascription factor - ExuR/UxuR
By taxonomy - Pasteurellales
By TF family - GntR/Others
By effector - Glucuronate
By pathway - Glucuronate utilization

Statistics of regulated genes
Genome	Genes	Operons
Haemophilus influenzae Rd KW20	9	2
Aggregatibacter aphrophilus NJ8700
Pasteurella multocida subsp. multocida str. Pm70
Mannheimia succiniciproducens MBEL55E	10	2
Actinobacillus succinogenes 130Z	9	3
Haemophilus somnus 2336	13	5
Actinobacillus pleuropneumoniae serovar 7 str. AP76
Haemophilus ducreyi 35000HP
Haemophilus parasuis SH0165

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes										Function

CRON 1.
uxuQ	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70	* Mannheimia succiniciproducens MBEL55E Site: position = -178 score = 5.02396 sequence = CAAATGGTATACCAAAAT Site: position = -63 score = 6.09772 sequence = ATATTGGTTTACCAATTT Gene: MS0541: predicted glucuronate TRAP transporter, small subunit	* Actinobacillus succinogenes 130Z Site: position = -171 score = 5.22353 sequence = AAAATGGTATACCGATTT Site: position = -56 score = 5.86956 sequence = ATATTGGTTTACCAATTA Gene: Asuc_0147: predicted glucuronate TRAP transporter, small subunit	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	predicted glucuronate TRAP transporter, small subunit
uxuM	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E Gene: MS0540: predicted glucuronate TRAP transporter, large subunit	Actinobacillus succinogenes 130Z Gene: Asuc_0148: predicted glucuronate TRAP transporter, large subunit	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	predicted glucuronate TRAP transporter, large subunit
lfaA	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E Gene: MS0539: Alpha-glucosidase (EC 3.2.1.20)	Actinobacillus succinogenes 130Z Gene: Asuc_0149: Alpha-glucosidase (EC 3.2.1.20)	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	Alpha-glucosidase (EC 3.2.1.20)
uxuR	* Haemophilus influenzae Rd KW20 Site: position = -78 score = 4.73721 sequence = TTTTTGGAATACCAAATA Site: position = -28 score = 5.63224 sequence = AAATTGGAATACCAATTT Gene: HI0054: Hexuronate utilization operon transcriptional repressor UxuR	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E Gene: MS0538: Hexuronate utilization operon transcriptional repressor UxuR	Actinobacillus succinogenes 130Z Gene: Asuc_0150: Hexuronate utilization operon transcriptional repressor UxuR	2 Haemophilus somnus 2336* Site: position = -68 score = 4.52116 sequence = AATTTGGTGAACCAGAAA Site: position = -196 score = 5.22709 sequence = AAACTGGTAAACCAGTTA Gene: HSM_0414: Hexuronate utilization operon transcriptional repressor UxuR Site: position = -78 score = 5.13342 sequence = TTTTTGGTATTCCAATTT Gene: HSM_1913: Hexuronate utilization operon transcriptional repressor UxuR	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	Hexuronate utilization operon transcriptional repressor UxuR
uxuA	Haemophilus influenzae Rd KW20 Gene: HI0055: Mannonate dehydratase (EC 4.2.1.8)	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E Gene: MS0537: Mannonate dehydratase (EC 4.2.1.8)	Actinobacillus succinogenes 130Z Gene: Asuc_0151: Mannonate dehydratase (EC 4.2.1.8)	Haemophilus somnus 2336 Gene: HSM_0415: Mannonate dehydratase (EC 4.2.1.8)	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	Mannonate dehydratase (EC 4.2.1.8)

CRON 2.
HI0053	* Haemophilus influenzae Rd KW20 Site: position = -150 score = 5.63716 sequence = AAATTGGTATTCCAATTT Site: position = -100 score = 4.6572 sequence = TATTTGGTATTCCAAAAA Gene: HI0053: Oxidoreductase, zinc-binding dehydrogenase family (EC 1.1.1.-)	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	* Haemophilus somnus 2336 Site: position = -101 score = 5.05053 sequence = AAATTGGAATACCAAAAA Gene: HSM_1914: Oxidoreductase, zinc-binding dehydrogenase family (EC 1.1.1.-)	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	Oxidoreductase, zinc-binding dehydrogenase family (EC 1.1.1.-)
uxuP	Haemophilus influenzae Rd KW20 Gene: HI0052: predicted glucuronate TRAP transporter, periplasmic subunit	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70	2 Mannheimia succiniciproducens MBEL55E* Site: position = -69 score = 5.98817 sequence = AAATTGGTAAACCAATAT Gene: MS0542: predicted glucuronate TRAP transporter, periplasmic subunit Gene: MS0526: predicted glucuronate TRAP transporter, periplasmic subunit	2 Actinobacillus succinogenes 130Z* Site: position = -85 score = 5.12543 sequence = AAATCGGTATACCATTTT Site: position = -200 score = 5.81867 sequence = TAATTGGTAAACCAATAT Gene: Asuc_0146: predicted glucuronate TRAP transporter, periplasmic subunit Gene: Asuc_0145: predicted glucuronate TRAP transporter, periplasmic subunit	Haemophilus somnus 2336 Gene: HSM_1915: predicted glucuronate TRAP transporter, periplasmic subunit	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	predicted glucuronate TRAP transporter, periplasmic subunit
uxuQ	Haemophilus influenzae Rd KW20 Gene: HI0051: predicted hexuronate TRAP transporter, small subunit	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E Gene: MS0527: predicted hexuronate TRAP transporter, small subunit	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336 Gene: HSM_1916: predicted hexuronate TRAP transporter, small subunit	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	predicted hexuronate TRAP transporter, small subunit
uxuM	Haemophilus influenzae Rd KW20 Gene: HI0050m: predicted hexuronate TRAP transporter, large subunit	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E Gene: MS0528: predicted hexuronate TRAP transporter, large subunit	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336 Gene: HSM_1917: predicted hexuronate TRAP transporter, large subunit	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	predicted hexuronate TRAP transporter, large subunit
kdgK	Haemophilus influenzae Rd KW20 Gene: HI0049: 2-dehydro-3-deoxygluconate kinase (EC 2.7.1.45)	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E Gene: MS0545: 2-dehydro-3-deoxygluconate kinase (EC 2.7.1.45)	Actinobacillus succinogenes 130Z Gene: Asuc_0153: 2-dehydro-3-deoxygluconate kinase (EC 2.7.1.45)	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	2-dehydro-3-deoxygluconate kinase (EC 2.7.1.45)
uxuB	Haemophilus influenzae Rd KW20 Gene: HI0048: D-mannonate oxidoreductase (EC 1.1.1.57)	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E Gene: MS0543: D-mannonate oxidoreductase (EC 1.1.1.57)	Actinobacillus succinogenes 130Z	* Haemophilus somnus 2336 Site: position = -199 score = 4.82761 sequence = TTTCTGGTTCACCAAATT Site: position = -71 score = 5.31038 sequence = TAACTGGTTTACCAGTTT Gene: HSM_0413: D-mannonate oxidoreductase (EC 1.1.1.57)	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	D-mannonate oxidoreductase (EC 1.1.1.57)
eda	Haemophilus influenzae Rd KW20 Gene: HI0047: 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14)	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E Gene: MS0546: 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14)	Actinobacillus succinogenes 130Z Gene: Asuc_0152: 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14)	Haemophilus somnus 2336 Gene: HSM_0408: 2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14)	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	2-dehydro-3-deoxyphosphogluconate aldolase (EC 4.1.2.14)
uxaC	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E Gene: MS0544: Uronate isomerase (EC 5.3.1.12)	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336 Gene: HSM_0409: Uronate isomerase (EC 5.3.1.12)	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	Uronate isomerase (EC 5.3.1.12)
uidA	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	* Haemophilus somnus 2336 Site: position = -119 score = 5.62151 sequence = AAATTGGTTTACCAAAAA Gene: HSM_0411: beta-D-glucuronidase	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	beta-D-glucuronidase
uidB	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336 Gene: HSM_0410: glucuronides GPH transporter	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	glucuronides GPH transporter
uxaA	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E Gene: MS0530: Altronate hydrolase (EC 4.2.1.7)	* Actinobacillus succinogenes 130Z Site: position = -227 score = 5.21752 sequence = ACATTGGTTGACGAATTT Gene: Asuc_0154: Altronate hydrolase (EC 4.2.1.7)	Haemophilus somnus 2336	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	Altronate hydrolase (EC 4.2.1.7)
HSM_0412	Haemophilus influenzae Rd KW20	Aggregatibacter aphrophilus NJ8700	Pasteurella multocida subsp. multocida str. Pm70	Mannheimia succiniciproducens MBEL55E	Actinobacillus succinogenes 130Z	Haemophilus somnus 2336 Gene: HSM_0412: hypothetical protein	Actinobacillus pleuropneumoniae serovar 7 str. AP76	Haemophilus ducreyi 35000HP	Haemophilus parasuis SH0165	hypothetical protein

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog UxuR - Pasteurellales

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --