Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Collection of regulogs for ExuR/UxuR transcription factor

General statistics
Genomes 64
TF regulogs 7
TF regulons 27
TF binding sites 166

The hexuronate metabolism in Escherichia coli is regulated by two related transcription regulators from the FadR subfamily of the GntR family, UxuR and ExuR. Both regulators were experimentally investigated in E. coli, however their DNA-binding motifs have been unknown. UxuR controls the D-glucuronate metabolism by repressing uxuAB, uidABC, gntP and its own gene uxuR. ExuR negatively controls most of the genes involved in the metabolism of both D-galacturonate and D-glucuronate, including exuT, uxaCA, uxaB, uxuAB, and exuR. Previous in silico analysis of the UxuR/ExuR regulon revealed a common DNA-binding motif with consensus AAATTGGTATACCAATTT in upstream regions of many known UxuR/ExuR-regulated genes [11115104]. more

Phylum Regulog TF regulons (studied genomes) TFBSs Logo
Proteobacteria UxuR - Oceanospirillales/Alteromonadales 1 (12) 5
Proteobacteria UxuR - Pasteurellales 4 (9) 19
Proteobacteria/alpha UxuR - Rhodobacterales 1 (15) 5
Proteobacteria/gamma ExuR - Enterobacteriales 8 (12) 48
Proteobacteria/gamma UxuR - Enterobacteriales 6 (12) 44
Proteobacteria/gamma UxuR - Psychromonadaceae/Aeromonadales 3 (6) 17
Proteobacteria/gamma UxuR - Vibrionales 4 (10) 28