Regulog NanR - Enterobacteriales

Properties
Regulator type:	Transcription factor
Regulator family:	GntR/Others
Regulation mode:	repressor (activator)
Biological process:	Sialic acid utilization
Effector:	N-acetylneuraminic acid
Phylum:	Proteobacteria/gamma
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 7 sites [see more]

Member of regulog collections

By taxonomy - Enterobacteriales
By TF family - GntR/Others
By effector - N-acetylneuraminic acid
By pathway - Sialic acid utilization

Statistics of regulated genes
Genome	Genes	Operons
Escherichia coli str. K-12 substr. MG1655	9	3
Salmonella typhimurium LT2	5	1
Citrobacter koseri ATCC BAA-895	2	1
Klebsiella pneumoniae subsp. pneumoniae MGH 78578
Enterobacter sp. 638	4	1
Erwinia amylovora ATCC 49946
Yersinia pestis KIM
Serratia proteamaculans 568
Erwinia carotovora subsp. atroseptica SCRI1043
Edwardsiella tarda EIB202	4	1
Proteus mirabilis HI4320
Photorhabdus luminescens subsp. laumondii TTO1

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes													Function

CRON 1.
nanC	* Escherichia coli str. K-12 substr. MG1655 Site: position = -443 score = 7.98092 sequence = CTGGTATAACAGGTATAAAGGTG Gene: b4311: N-acetylneuraminic acid outer membrane channel protein NanC	Salmonella typhimurium LT2	Citrobacter koseri ATCC BAA-895	Klebsiella pneumoniae subsp. pneumoniae MGH 78578	Enterobacter sp. 638	Erwinia amylovora ATCC 49946	Yersinia pestis KIM	Serratia proteamaculans 568	Erwinia carotovora subsp. atroseptica SCRI1043	Edwardsiella tarda EIB202	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1	N-acetylneuraminic acid outer membrane channel protein NanC
nanM	Escherichia coli str. K-12 substr. MG1655 Gene: b4310: Sialic acid-induced transmembrane protein YjhT(NanM), possible mutarotase	Salmonella typhimurium LT2	Citrobacter koseri ATCC BAA-895	Klebsiella pneumoniae subsp. pneumoniae MGH 78578	Enterobacter sp. 638	Erwinia amylovora ATCC 49946	Yersinia pestis KIM	Serratia proteamaculans 568	Erwinia carotovora subsp. atroseptica SCRI1043	Edwardsiella tarda EIB202	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1	Sialic acid-induced transmembrane protein YjhT(NanM), possible mutarotase

CRON 2.
yjhB	* Escherichia coli str. K-12 substr. MG1655 Site: position = -436 score = 8.23343 sequence = CTGGTATAACAGGTATAAAGGTA Gene: b4279: a paralog of sialic acid transporter	Salmonella typhimurium LT2 Gene: STM1132: a paralog of sialic acid transporter	Citrobacter koseri ATCC BAA-895	Klebsiella pneumoniae subsp. pneumoniae MGH 78578	Enterobacter sp. 638	Erwinia amylovora ATCC 49946	Yersinia pestis KIM	Serratia proteamaculans 568	Erwinia carotovora subsp. atroseptica SCRI1043	Edwardsiella tarda EIB202	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1	a paralog of sialic acid transporter
yjhC	Escherichia coli str. K-12 substr. MG1655 Gene: b4280: putative dehydrogenase	Salmonella typhimurium LT2 Gene: STM1133: putative dehydrogenase	Citrobacter koseri ATCC BAA-895	Klebsiella pneumoniae subsp. pneumoniae MGH 78578	Enterobacter sp. 638	Erwinia amylovora ATCC 49946	Yersinia pestis KIM	Serratia proteamaculans 568	Erwinia carotovora subsp. atroseptica SCRI1043	Edwardsiella tarda EIB202	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1	putative dehydrogenase

CRON 3.
nanA	* Escherichia coli str. K-12 substr. MG1655 Site: position = -60 score = 8.23343 sequence = CTGGTATAACAGGTATAAAGGTA Gene: b3225: N-acetylneuraminate lyase (EC 4.1.3.3)	* Salmonella typhimurium LT2 Site: position = -58 score = 8.23343 sequence = CTGGTATAACAGGTATAAAGGTA Gene: STM3339: N-acetylneuraminate lyase (EC 4.1.3.3)	* Citrobacter koseri ATCC BAA-895 Site: position = -60 score = 8.23343 sequence = CTGGTATAACAGGTATAAAGGTA Gene: CKO_04629: N-acetylneuraminate lyase (EC 4.1.3.3)	Klebsiella pneumoniae subsp. pneumoniae MGH 78578	* Enterobacter sp. 638 Site: position = -57 score = 8.23343 sequence = CTGGTATAACAGGTATAAAGGTA Gene: Ent638_3661: N-acetylneuraminate lyase (EC 4.1.3.3)	Erwinia amylovora ATCC 49946	Yersinia pestis KIM	Serratia proteamaculans 568	Erwinia carotovora subsp. atroseptica SCRI1043	* Edwardsiella tarda EIB202 Site: position = -85 score = 7.98092 sequence = CTGGTATAACAGGTATACAGGTA Gene: ETAE_1381: N-acetylneuraminate lyase (EC 4.1.3.3)	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1	N-acetylneuraminate lyase (EC 4.1.3.3)
nanT	Escherichia coli str. K-12 substr. MG1655 Gene: b3224: Sialic acid transporter (permease) NanT	Salmonella typhimurium LT2 Gene: STM3338: Sialic acid transporter (permease) NanT	Citrobacter koseri ATCC BAA-895 Gene: CKO_04628: Sialic acid transporter (permease) NanT	Klebsiella pneumoniae subsp. pneumoniae MGH 78578	Enterobacter sp. 638 Gene: Ent638_3660: Sialic acid transporter (permease) NanT	Erwinia amylovora ATCC 49946	Yersinia pestis KIM	Serratia proteamaculans 568	Erwinia carotovora subsp. atroseptica SCRI1043	Edwardsiella tarda EIB202 Gene: ETAE_1382: Sialic acid transporter (permease) NanT	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1	Sialic acid transporter (permease) NanT
nanE	Escherichia coli str. K-12 substr. MG1655 Gene: b3223: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)	Salmonella typhimurium LT2 Gene: STM3337: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)	Citrobacter koseri ATCC BAA-895 Gene: CKO_04626: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)	Klebsiella pneumoniae subsp. pneumoniae MGH 78578	Enterobacter sp. 638	Erwinia amylovora ATCC 49946	Yersinia pestis KIM	Serratia proteamaculans 568	Erwinia carotovora subsp. atroseptica SCRI1043	Edwardsiella tarda EIB202	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1	N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)
nanK	Escherichia coli str. K-12 substr. MG1655 Gene: b3222: N-acetylmannosamine kinase (EC 2.7.1.60)	Salmonella typhimurium LT2 Gene: STM3336: N-acetylmannosamine kinase (EC 2.7.1.60)	Citrobacter koseri ATCC BAA-895 Gene: CKO_04625: N-acetylmannosamine kinase (EC 2.7.1.60)	Klebsiella pneumoniae subsp. pneumoniae MGH 78578	Enterobacter sp. 638 Gene: Ent638_3659: N-acetylmannosamine kinase (EC 2.7.1.60)	Erwinia amylovora ATCC 49946	Yersinia pestis KIM	Serratia proteamaculans 568	Erwinia carotovora subsp. atroseptica SCRI1043	Edwardsiella tarda EIB202 Gene: ETAE_1383: N-acetylmannosamine kinase (EC 2.7.1.60)	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1	N-acetylmannosamine kinase (EC 2.7.1.60)
yhcH	Escherichia coli str. K-12 substr. MG1655 Gene: b3221: Uncharacterized protein yhcH	Salmonella typhimurium LT2 Gene: STM3335: Uncharacterized protein yhcH	Citrobacter koseri ATCC BAA-895 Gene: CKO_04624: Uncharacterized protein yhcH	Klebsiella pneumoniae subsp. pneumoniae MGH 78578	Enterobacter sp. 638 Gene: Ent638_3658: Uncharacterized protein yhcH	Erwinia amylovora ATCC 49946	Yersinia pestis KIM	Serratia proteamaculans 568	Erwinia carotovora subsp. atroseptica SCRI1043	Edwardsiella tarda EIB202 Gene: ETAE_1384: Uncharacterized protein yhcH	Proteus mirabilis HI4320	Photorhabdus luminescens subsp. laumondii TTO1	Uncharacterized protein yhcH

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog NanR - Enterobacteriales

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --