Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of NanR in Escherichia coli str. K-12 substr. MG1655

Properties
Regulator type: Transcription factor
TF locus tag: b3226
Regulator family: GntR/Others
Regulation mode: repressor (activator)
Biological process: Sialic acid utilization
Effector: N-acetylneuraminic acid
Regulog: NanR - Enterobacteriales
Statistics of regulated genes:
- Genes 9
- Operons 3
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 7 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -60
Score: 8.2
Sequence: CTGGTATAACAGGTATAAAGGTA
Locus tag: b3225
Name: nanA
Funciton: N-acetylneuraminate lyase (EC 4.1.3.3)
Locus tag: b3224
Name: nanT
Funciton: Sialic acid transporter (permease) NanT
Locus tag: b3223
Name: nanE
Funciton: N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)
Locus tag: b3222
Name: nanK
Funciton: N-acetylmannosamine kinase (EC 2.7.1.60)
Locus tag: b3221
Name: yhcH
Funciton: Uncharacterized protein yhcH
nanA
N-acetylneuraminate lyase (EC 4.1.3.3)
nanT
Sialic acid transporter (permease) NanT
nanE
N-acetylmannosamine-6-phosphate 2-epimerase (EC 5.1.3.9)
nanK
N-acetylmannosamine kinase (EC 2.7.1.60)
yhcH
Uncharacterized protein yhcH

Position: -443
Score: 8
Sequence: CTGGTATAACAGGTATAAAGGTG
Locus tag: b4311
Name: nanC
Funciton: N-acetylneuraminic acid outer membrane channel protein NanC
Locus tag: b4310
Name: nanM
Funciton: Sialic acid-induced transmembrane protein YjhT(NanM), possible mutarotase
nanC
N-acetylneuraminic acid outer membrane channel protein NanC
nanM
Sialic acid-induced transmembrane protein YjhT(NanM), possible mutarotase

Position: -436
Score: 8.2
Sequence: CTGGTATAACAGGTATAAAGGTA
Locus tag: b4279
Name: yjhB
Funciton: a paralog of sialic acid transporter
Locus tag: b4280
Name: yjhC
Funciton: putative dehydrogenase
yjhB
a paralog of sialic acid transporter
yjhC
putative dehydrogenase
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Regulated Genes [ Tab delimited format ] DOWNLOAD
Regulatory Sites [ FASTA format ] DOWNLOAD