Regulog HypR - Rhizobiales
| Regulator type: | Transcription factor |
| Regulator family: | GntR/Others |
| Regulation mode: | activator (repressor) |
| Biological process: | Proline and 4-hydrohyproline utilization |
| Effector: | Proline |
| Phylum: | Proteobacteria/alpha |
| Visualization: | |
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Allows to visualize regulog content in the context of metabolic pathways |
Member of regulog collections
- By taxonomy - Rhizobiales
- By trascription factor - HypR
- By TF family - GntR/Others
- By effector - Proline
- By pathway - Proline and 4-hydrohyproline utilization
| Genome | Genes | Operons |
|---|---|---|
| Sinorhizobium meliloti 1021 | 14 | 5 |
| Rhizobium sp. NGR234 | ||
| Rhizobium leguminosarum bv. viciae 3841 | 2 | 2 |
| Rhizobium etli CFN 42 | 2 | 2 |
| Agrobacterium tumefaciens str. C58 (Cereon) | 10 | 4 |
| Mesorhizobium sp. BNC1 | 2 | 2 |
| Mesorhizobium loti MAFF303099 | ||
| Brucella melitensis 16M | 1 | 1 |
| Bartonella quintana str. Toulouse | ||
| Rhodopseudomonas palustris CGA009 | ||
| Bradyrhizobium japonicum USDA 110 | ||
| Bradyrhizobium sp. BTAi1 | ||
| Nitrobacter winogradskyi Nb-255 | ||
| Azorhizobium caulinodans ORS 571 | ||
| Xanthobacter autotrophicus Py2 |
| Genes | Function | |||||||||||||||
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| CRON 1. | ||||||||||||||||
| hypS |
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Sinorhizobium meliloti 1021 Site: position = -71 score = 3.81704 sequence = GTTTGTATACTCTA Gene: SMb20261: Putative L-lactate/Malate dehydrogenase |
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Agrobacterium tumefaciens str. C58 (Cereon) Site: position = -52 score = 3.46455 sequence = CTTTGTATACTTTA Site: position = -232 score = 4.18237 sequence = ATGAGTATACAAAA Site: position = -41 score = 3.72489 sequence = TTATGTATTCAAAA Gene: Atu4676: Putative L-lactate/Malate dehydrogenase |
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Gene: BMEII1005: Putative L-lactate/Malate dehydrogenase |
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Putative L-lactate/Malate dehydrogenase |
| hypT |
Gene: SMb20260: Putative hydroxyproline transporter |
Gene: NGR_b14200: Putative hydroxyproline transporter |
Gene: RL1805: Putative hydroxyproline transporter |
Gene: RHE_CH01706: Putative hydroxyproline transporter |
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Gene: Meso_0754: Putative hydroxyproline transporter |
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Putative hydroxyproline transporter |
| CRON 2. | ||||||||||||||||
| hypD |
*2
Sinorhizobium meliloti 1021 Gene: SMc03259: 1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) # predicted Site: position = -108 score = 5.12511 sequence = TTTTGTCGACAAAT Gene: SMb20259: 1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) # predicted |
Gene: NGR_c13110: 1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) # predicted |
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Rhizobium leguminosarum bv. viciae 3841 Site: position = -51 score = 4.56911 sequence = TCTTGTCGACAGTT Gene: pRL100268: 1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) # predicted |
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Rhizobium etli CFN 42 Site: position = -51 score = 4.56911 sequence = TCTTGTCGACAGTT Gene: RHE_PC00042: 1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) # predicted |
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Agrobacterium tumefaciens str. C58 (Cereon) Site: position = -99 score = 5.09177 sequence = TCTTGTCGACAAAT Gene: Atu4675: 1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) # predicted |
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Mesorhizobium sp. BNC1 Site: position = -71 score = 4.60882 sequence = TTGTGTCGACAAAC Gene: Meso_2568: 1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) # predicted |
3
Mesorhizobium loti MAFF303099 Gene: mlr6292: 1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) # predicted Gene: mll3981: 1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) # predicted Gene: mll6811: 1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) # predicted |
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Brucella melitensis 16M Site: position = -89 score = 5.23266 sequence = TCTTGTCGACAAGA Gene: BMEII1006: 1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) # predicted |
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Gene: bll4423: 1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) # predicted |
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Gene: Xaut_2517: 1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) # predicted |
1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) # predicted |
| CRON 3. | ||||||||||||||||
| hypM |
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Sinorhizobium meliloti 1021 Site: position = -101 score = 4.50138 sequence = TTTTGTATACTAAT Gene: SMb20263: Predicted hydroxyproline ABC transporter, substrate-binding protein |
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Agrobacterium tumefaciens str. C58 (Cereon) Site: position = -100 score = 4.18237 sequence = TTTTGTATACTCAT Gene: Atu4678: Predicted hydroxyproline ABC transporter, substrate-binding protein |
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Predicted hydroxyproline ABC transporter, substrate-binding protein |
| hypN |
Gene: SMb20264: Predicted hydroxyproline ABC transporter, permease protein |
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Gene: Atu4679: Predicted hydroxyproline ABC transporter, permease protein |
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Predicted hydroxyproline ABC transporter, permease protein |
| hypP |
Gene: SMb20265: Predicted hydroxyproline ABC transporter, permease protein |
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Gene: Atu4680: Predicted hydroxyproline ABC transporter, permease protein |
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Predicted hydroxyproline ABC transporter, permease protein |
| hypQ |
Gene: SMb20266: Predicted hydroxyproline ABC transporter, ATP-binding protein |
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Gene: Atu4681: Predicted hydroxyproline ABC transporter, ATP-binding protein |
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Predicted hydroxyproline ABC transporter, ATP-binding protein |
| hypO |
Gene: SMb20267: D-amino acid dehydrogenase (EC 1.4.99.1) family protein in hydroxy-L-proline catabolic cluster |
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2
Agrobacterium tumefaciens str. C58 (Cereon) Gene: Atu3364: D-amino acid dehydrogenase (EC 1.4.99.1) family protein in hydroxy-L-proline catabolic cluster Gene: Atu4682: D-amino acid dehydrogenase (EC 1.4.99.1) family protein in hydroxy-L-proline catabolic cluster |
Gene: Meso_3322: D-amino acid dehydrogenase (EC 1.4.99.1) family protein in hydroxy-L-proline catabolic cluster |
Gene: mll3980: D-amino acid dehydrogenase (EC 1.4.99.1) family protein in hydroxy-L-proline catabolic cluster |
Gene: BMEI0256: D-amino acid dehydrogenase (EC 1.4.99.1) family protein in hydroxy-L-proline catabolic cluster |
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D-amino acid dehydrogenase (EC 1.4.99.1) family protein in hydroxy-L-proline catabolic cluster |
| hypE |
Gene: SMb20268: Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8) |
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Gene: pRL120535: Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8) |
Gene: RHE_PF00391: Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8) |
Gene: Atu3953: Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8) |
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Gene: mll3979: Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8) |
Gene: BMEI0257: Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8) |
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Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8) |
| hypX |
Gene: SMb20269: Putative citrate/isocitrate isomerase or aconitase ## predicted from clustering to proline racemase |
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Gene: Atu4683: Putative citrate/isocitrate isomerase or aconitase ## predicted from clustering to proline racemase |
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Putative citrate/isocitrate isomerase or aconitase ## predicted from clustering to proline racemase |
| hypY |
Gene: SMb20270: Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8), possible pseudogene, inactive |
Gene: NGR_c20530: Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8), possible pseudogene, inactive |
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Gene: Atu4684: Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8), possible pseudogene, inactive |
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Gene: mlr6810: Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8), possible pseudogene, inactive |
Gene: BMEI1586: Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8), possible pseudogene, inactive |
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Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8), possible pseudogene, inactive |
| hypZ |
Gene: SMb20271: OsmC/Ohr family protein |
Gene: NGR_b08950: OsmC/Ohr family protein |
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Gene: mll0741: OsmC/Ohr family protein |
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OsmC/Ohr family protein |
| CRON 4. | ||||||||||||||||
| hypH |
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Sinorhizobium meliloti 1021 Site: position = -185 score = 3.81704 sequence = TAGAGTATACAAAC Gene: SMb20262: Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) # hydroxy-L-proline-inducible |
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Gene: pRL120235: Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) # hydroxy-L-proline-inducible |
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Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) # hydroxy-L-proline-inducible |
| CRON 5. | ||||||||||||||||
| hypR |
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Sinorhizobium meliloti 1021 Site: position = -24 score = 5.266 sequence = TTTTGTCGACAAGA Gene: SMb20258: Predicted regulator for proline and hydrohyproline utilization, GntR family |
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Rhizobium leguminosarum bv. viciae 3841 Site: position = -113 score = 4.56911 sequence = AACTGTCGACAAGA Gene: pRL100269: Predicted regulator for proline and hydrohyproline utilization, GntR family |
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Rhizobium etli CFN 42 Site: position = -93 score = 4.56911 sequence = AACTGTCGACAAGA Gene: RHE_PC00043: Predicted regulator for proline and hydrohyproline utilization, GntR family |
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Agrobacterium tumefaciens str. C58 (Cereon) Site: position = -25 score = 4.73111 sequence = TTATGTCGACAAGA Gene: Atu4674: Predicted regulator for proline and hydrohyproline utilization, GntR family |
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Mesorhizobium sp. BNC1 Site: position = -143 score = 3.41635 sequence = ACGTGTTTACAATC Gene: Meso_2569: Predicted regulator for proline and hydrohyproline utilization, GntR family |
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Gene: BMEII1007: Predicted regulator for proline and hydrohyproline utilization, GntR family |
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Predicted regulator for proline and hydrohyproline utilization, GntR family |
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
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Regulatory Sites | [ FASTA format ] | DOWNLOAD |