Regulon of HypR in Sinorhizobium meliloti 1021

Properties
Regulator type:	Transcription factor
TF locus tag:	SMb20258
Regulator family:	GntR/Others
Regulation mode:	activator (repressor)
Biological process:	Proline and 4-hydrohyproline utilization
Effector:	Proline
Regulog:	HypR - Rhizobiales
Statistics of regulated genes:
- Genes	14
- Operons	5
Visualization:
	Allows to visualize regulon content in the context of metabolic pathways

Built upon 18 sites [see more]

Member of regulog collections

By taxonomy - Rhizobiales
By trascription factor - HypR
By TF family - GntR/Others
By effector - Proline
By pathway - Proline and 4-hydrohyproline utilization

Regulated operons
	Locus Tag	Name	Function
Position: -71 Score: 3.8 Sequence: GTTTGTATACTCTA Locus tag: SMb20261 Name: hypS Funciton: Putative L-lactate/Malate dehydrogenase Locus tag: SMb20260 Name: hypT Funciton: Putative hydroxyproline transporter
	SMb20261	hypS	Putative L-lactate/Malate dehydrogenase
	SMb20260	hypT	Putative hydroxyproline transporter
Position: -101 Score: 4.5 Sequence: TTTTGTATACTAAT Locus tag: SMb20263 Name: hypM Funciton: Predicted hydroxyproline ABC transporter, substrate-binding protein Locus tag: SMb20264 Name: hypN Funciton: Predicted hydroxyproline ABC transporter, permease protein Locus tag: SMb20265 Name: hypP Funciton: Predicted hydroxyproline ABC transporter, permease protein Locus tag: SMb20266 Name: hypQ Funciton: Predicted hydroxyproline ABC transporter, ATP-binding protein Locus tag: SMb20267 Name: hypO Funciton: D-amino acid dehydrogenase (EC 1.4.99.1) family protein in hydroxy-L-proline catabolic cluster Locus tag: SMb20268 Name: hypE Funciton: Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8) Locus tag: SMb20269 Name: hypX Funciton: Putative citrate/isocitrate isomerase or aconitase ## predicted from clustering to proline racemase Locus tag: SMb20270 Name: hypY Funciton: Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8), possible pseudogene, inactive Locus tag: SMb20271 Name: hypZ Funciton: OsmC/Ohr family protein
	SMb20263	hypM	Predicted hydroxyproline ABC transporter, substrate-binding protein
	SMb20264	hypN	Predicted hydroxyproline ABC transporter, permease protein
	SMb20265	hypP	Predicted hydroxyproline ABC transporter, permease protein
	SMb20266	hypQ	Predicted hydroxyproline ABC transporter, ATP-binding protein
	SMb20267	hypO	D-amino acid dehydrogenase (EC 1.4.99.1) family protein in hydroxy-L-proline catabolic cluster
	SMb20268	hypE	Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8)
	SMb20269	hypX	Putative citrate/isocitrate isomerase or aconitase ## predicted from clustering to proline racemase
	SMb20270	hypY	Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8), possible pseudogene, inactive
	SMb20271	hypZ	OsmC/Ohr family protein
Position: -24 Score: 5.3 Sequence: TTTTGTCGACAAGA Locus tag: SMb20258 Name: hypR Funciton: Predicted regulator for proline and hydrohyproline utilization, GntR family
	SMb20258	hypR	Predicted regulator for proline and hydrohyproline utilization, GntR family
Position: -108 Score: 5.1 Sequence: TTTTGTCGACAAAT Locus tag: SMb20259 Name: hypD Funciton: 1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) # predicted
	SMb20259	hypD	1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) # predicted
Position: -185 Score: 3.8 Sequence: TAGAGTATACAAAC Locus tag: SMb20262 Name: hypH Funciton: Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) # hydroxy-L-proline-inducible
	SMb20262	hypH	Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) # hydroxy-L-proline-inducible

Export
	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD