Collection of regulogs for HypR transcription factor
| Genomes | 126 |
| TF regulogs | 13 |
| TF regulons | 46 |
| TF binding sites | 193 |
Transcription factor HypR from the GntR protein family regulates the proline and 4-hydrohyproline utilization genes in Proteobacteria. The HypR regulon and its DNA-binding motif were discovered by application of the comparative genomic approach, first in Shewanella spp. [21810205], where it controls proline dehydrogenase putA and hydrohyproline utilization genes hyp. Recently, HypR regulon was confirmed in Sinorhizobium meliloti, where a set of 4-hydroxyproline induced genes was found under regulation of HypR repressor [22804907].
| Phylum | Regulog | TF regulons (studied genomes) | TFBSs | Logo |
|---|---|---|---|---|
| Proteobacteria/alpha | HypR - Rhizobiales | 6 (15) | 18 |  |
| Proteobacteria/alpha | HypR - Rhodobacterales | 3 (15) | 10 |  |
| Proteobacteria/alpha | HypR2 - Rhodobacterales | 5 (15) | 17 |  |
| Proteobacteria/alpha | HypR - Rhodospirillales | 1 (9) | 1 |  |
| Proteobacteria/beta | HypR - Burkholderia | 3 (8) | 5 |  |
| Proteobacteria/beta | HypR - Ralstonia | 1 (6) | 2 |  |
| Proteobacteria/gamma | HypR - Alteromonadales | 3 (9) | 21 |  |
| Proteobacteria/gamma | HypR - Enterobacteriales | 1 (12) | 1 |  |
| Proteobacteria/gamma | HypR - Oceanospirillales/Alteromonadales | 2 (12) | 6 |  |
| Proteobacteria/gamma | HypR - Pseudomonadaceae | 1 (8) | 3 |  |
| Proteobacteria/gamma | HypR - Psychromonadaceae/Aeromonadales | 3 (6) | 8 |  |
| Proteobacteria/gamma | HypR - Shewanellaceae | 16 (16) | 96 |  |
| Proteobacteria/gamma | HypR - Vibrionales | 1 (10) | 5 |  |