Regulog HypR - Oceanospirillales/Alteromonadales

Properties
Regulator type:	Transcription factor
Regulator family:	GntR/Others
Regulation mode:	activator (repressor)
Biological process:	Proline and 4-hydrohyproline utilization
Effector:	Proline; 4-hydroxyproline
Phylum:	Proteobacteria/gamma
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 6 sites [see more]

Member of regulog collections

By taxonomy - Oceanospirillales/Alteromonadales
By trascription factor - HypR
By TF family - GntR/Others
By effector - Proline
By effector - 4-hydroxyproline
By pathway - Proline and 4-hydrohyproline utilization

Statistics of regulated genes
Genome	Genes	Operons
Hahella chejuensis KCTC 2396	5	3
Marinobacter aqueolei
Marinobacter sp. ELB17
Oceanobacter sp. RED65
Oceanospirillum sp. MED92
Marinomonas sp. MWYL1
Saccharophagus degradans 2-40
Teredinibacter turnerae T7901
Cellvibrio japonicus Ueda107
Chromohalobacter salexigens DSM 3043	4	3
Reinekea sp. MED297
Alcanivorax borkumensis SK2

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes													Function

CRON 1.
hypO	* Hahella chejuensis KCTC 2396 Site: position = -42 score = 4.94466 sequence = ATTTTATACAAT Gene: HCH_03166: D-amino acid dehydrogenase (EC 1.4.99.1) family protein in hydroxy-L-proline catabolic cluster	Marinobacter aqueolei	Marinobacter sp. ELB17	Oceanobacter sp. RED65	Oceanospirillum sp. MED92	Marinomonas sp. MWYL1	Saccharophagus degradans 2-40	Teredinibacter turnerae T7901	Cellvibrio japonicus Ueda107	* Chromohalobacter salexigens DSM 3043 Site: position = -49 score = 4.94466 sequence = ATTTTATACAAT Gene: Csal_2708: D-amino acid dehydrogenase (EC 1.4.99.1) family protein in hydroxy-L-proline catabolic cluster	Reinekea sp. MED297	Alcanivorax borkumensis SK2	D-amino acid dehydrogenase (EC 1.4.99.1) family protein in hydroxy-L-proline catabolic cluster

CRON 2.
hypE	* Hahella chejuensis KCTC 2396 Site: position = -129 score = 4.94466 sequence = ATTGTATAAAAT Gene: HCH_03167: Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8)	Marinobacter aqueolei	Marinobacter sp. ELB17	Oceanobacter sp. RED65	Oceanospirillum sp. MED92	Marinomonas sp. MWYL1	Saccharophagus degradans 2-40	Teredinibacter turnerae T7901	Cellvibrio japonicus Ueda107	* Chromohalobacter salexigens DSM 3043 Site: position = -45 score = 4.94466 sequence = ATTGTATAAAAT Gene: Csal_2705: Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8)	Reinekea sp. MED297	Alcanivorax borkumensis SK2	Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8)
hypD	Hahella chejuensis KCTC 2396	Marinobacter aqueolei	Marinobacter sp. ELB17	Oceanobacter sp. RED65	Oceanospirillum sp. MED92	Marinomonas sp. MWYL1	Saccharophagus degradans 2-40	Teredinibacter turnerae T7901	Cellvibrio japonicus Ueda107	Chromohalobacter salexigens DSM 3043 Gene: Csal_2706: 1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) # predicted	Reinekea sp. MED297	Alcanivorax borkumensis SK2	1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) # predicted
hypR	Hahella chejuensis KCTC 2396 Gene: HCH_03168: Predicted regulator for proline and hydrohyproline utilization, GntR family	Marinobacter aqueolei	Marinobacter sp. ELB17	Oceanobacter sp. RED65	Oceanospirillum sp. MED92	Marinomonas sp. MWYL1	Saccharophagus degradans 2-40	Teredinibacter turnerae T7901	Cellvibrio japonicus Ueda107	* Chromohalobacter salexigens DSM 3043 Site: position = -44 score = 4.0189 sequence = GTTGTATACAGT Gene: Csal_2707: Predicted regulator for proline and hydrohyproline utilization, GntR family	Reinekea sp. MED297	Alcanivorax borkumensis SK2	Predicted regulator for proline and hydrohyproline utilization, GntR family

CRON 3.
hypD-related, COG329 (DapA)	* Hahella chejuensis KCTC 2396 Site: position = -118 score = 5.32149 sequence = ATTGTATACAAT Gene: HCH_03163: 1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22)	Marinobacter aqueolei	Marinobacter sp. ELB17	Oceanobacter sp. RED65	Oceanospirillum sp. MED92	Marinomonas sp. MWYL1	Saccharophagus degradans 2-40	Teredinibacter turnerae T7901	Cellvibrio japonicus Ueda107	Chromohalobacter salexigens DSM 3043	Reinekea sp. MED297	Alcanivorax borkumensis SK2	1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22)
hypH-related, COG1012 (PutA)	Hahella chejuensis KCTC 2396 Gene: HCH_03162: Aldehyde dehydrogenase (EC 1.2.1.3), possibly ketoglutarate semialdehyde dehydrogenase	Marinobacter aqueolei	Marinobacter sp. ELB17	Oceanobacter sp. RED65	Oceanospirillum sp. MED92	Marinomonas sp. MWYL1	Saccharophagus degradans 2-40	Teredinibacter turnerae T7901	Cellvibrio japonicus Ueda107	Chromohalobacter salexigens DSM 3043	Reinekea sp. MED297	Alcanivorax borkumensis SK2	Aldehyde dehydrogenase (EC 1.2.1.3), possibly ketoglutarate semialdehyde dehydrogenase

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

Export
	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog HypR - Oceanospirillales/Alteromonadales

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --