Regulog HypR - Alteromonadales

Properties
Regulator type:	Transcription factor
Regulator family:	GntR/Others
Regulation mode:	activator (repressor)
Biological process:	Proline and 4-hydrohyproline utilization
Effector:	Proline; 4-hydroxyproline
Phylum:	Proteobacteria/gamma
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 21 sites [see more]

Member of regulog collections

By taxonomy - Alteromonadales
By trascription factor - HypR
By TF family - GntR/Others
By effector - Proline
By effector - 4-hydroxyproline
By pathway - Proline and 4-hydrohyproline utilization

Statistics of regulated genes
Genome	Genes	Operons
Pseudoalteromonas atlantica T6c
Alteromonas macleodii 'Deep ecotype'
Glaciecola sp. HTCC2999
Colwellia psychrerythraea 34H	6	5
Alteromonadales bacterium TW-7	8	6
Pseudoalteromonas haloplanktis TAC125
Pseudoalteromonas tunicata D2	9	6
Idiomarina baltica OS145
Idiomarina loihiensis L2TR

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes										Function

CRON 1.
omp, COG1629 (CirA)	Pseudoalteromonas atlantica T6c	Alteromonas macleodii 'Deep ecotype'	Glaciecola sp. HTCC2999	* Colwellia psychrerythraea 34H Site: position = -162 score = 4.16637 sequence = ATAATATACAAT Gene: CPS_4791: TonB-dependent receptor, collagen-binding surface protein	* Alteromonadales bacterium TW-7 Site: position = -86 score = 5.32149 sequence = ATTGTATACAAT Gene: ATW7_13093: TonB-dependent receptor, collagen-binding surface protein	Pseudoalteromonas haloplanktis TAC125	* Pseudoalteromonas tunicata D2 Site: position = -54 score = 5.32149 sequence = ATTGTATACAAT Gene: PTD2_02396: TonB-dependent receptor, collagen-binding surface protein	Idiomarina baltica OS145	Idiomarina loihiensis L2TR	TonB-dependent receptor, collagen-binding surface protein

CRON 2.
ATW7_13133	Pseudoalteromonas atlantica T6c	Alteromonas macleodii 'Deep ecotype'	Glaciecola sp. HTCC2999	Colwellia psychrerythraea 34H	* Alteromonadales bacterium TW-7 Site: position = -36 score = 5.32149 sequence = ATTGTATACAAT Gene: ATW7_13133: hypothetical protein	Pseudoalteromonas haloplanktis TAC125	Pseudoalteromonas tunicata D2	Idiomarina baltica OS145	Idiomarina loihiensis L2TR	hypothetical protein

CRON 3.
hypD	Pseudoalteromonas atlantica T6c	Alteromonas macleodii 'Deep ecotype'	Glaciecola sp. HTCC2999	* Colwellia psychrerythraea 34H Site: position = -100 score = 5.32149 sequence = ATTGTATACAAT Gene: CPS_1449: 1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) # predicted	* Alteromonadales bacterium TW-7 Site: position = -45 score = 4.7364 sequence = ACTGTATACAAT Gene: ATW7_13098: 1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) # predicted	Pseudoalteromonas haloplanktis TAC125	* Pseudoalteromonas tunicata D2 Site: position = -65 score = 5.01168 sequence = ATTGCATACAAT Gene: PTD2_14397: 1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) # predicted	Idiomarina baltica OS145	Idiomarina loihiensis L2TR	1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) # predicted
hypE	Pseudoalteromonas atlantica T6c	Alteromonas macleodii 'Deep ecotype'	Glaciecola sp. HTCC2999	Colwellia psychrerythraea 34H Gene: CPS_1450: Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8)	* Alteromonadales bacterium TW-7 Site: position = -276 score = 5.32149 sequence = ATTGTATACAAT Gene: ATW7_13113: Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8)	Pseudoalteromonas haloplanktis TAC125	Pseudoalteromonas tunicata D2 Gene: PTD2_14402: Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8)	Idiomarina baltica OS145	Idiomarina loihiensis L2TR	Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8)
hypH	Pseudoalteromonas atlantica T6c	Alteromonas macleodii 'Deep ecotype'	Glaciecola sp. HTCC2999	Colwellia psychrerythraea 34H Gene: CPS_1451: Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) # hydroxy-L-proline-inducible	Alteromonadales bacterium TW-7 Gene: ATW7_13108: Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) # hydroxy-L-proline-inducible	Pseudoalteromonas haloplanktis TAC125	Pseudoalteromonas tunicata D2 Gene: PTD2_14407: Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) # hydroxy-L-proline-inducible	Idiomarina baltica OS145	Idiomarina loihiensis L2TR	Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) # hydroxy-L-proline-inducible
hypR	Pseudoalteromonas atlantica T6c	Alteromonas macleodii 'Deep ecotype'	Glaciecola sp. HTCC2999	* Colwellia psychrerythraea 34H Site: position = 6 score = 4.03261 sequence = ATAGTATATAAA Gene: CPS_4142: Predicted regulator for proline and hydrohyproline utilization, GntR family	* Alteromonadales bacterium TW-7 Site: position = -33 score = 3.89307 sequence = AATGTATGCTAA Gene: ATW7_13103: Predicted regulator for proline and hydrohyproline utilization, GntR family	Pseudoalteromonas haloplanktis TAC125	Pseudoalteromonas tunicata D2 Gene: PTD2_14412: Predicted regulator for proline and hydrohyproline utilization, GntR family	Idiomarina baltica OS145	Idiomarina loihiensis L2TR	Predicted regulator for proline and hydrohyproline utilization, GntR family
ypdF	Pseudoalteromonas atlantica T6c	Alteromonas macleodii 'Deep ecotype'	Glaciecola sp. HTCC2999	Colwellia psychrerythraea 34H	Alteromonadales bacterium TW-7	Pseudoalteromonas haloplanktis TAC125	* Pseudoalteromonas tunicata D2 Site: position = -69 score = 5.01168 sequence = ATTGTATGCAAT Gene: PTD2_06274: Aminopeptidase YpdF (MP-, MA-, MS-, AP-, NP- specific)	Idiomarina baltica OS145	Idiomarina loihiensis L2TR	Aminopeptidase YpdF (MP-, MA-, MS-, AP-, NP- specific)

CRON 4.
colA2	Pseudoalteromonas atlantica T6c	Alteromonas macleodii 'Deep ecotype'	Glaciecola sp. HTCC2999	* Colwellia psychrerythraea 34H Site: position = -49 score = 5.01168 sequence = ATTGTATGCAAT Site: position = -32 score = 4.33388 sequence = ATTTTATTCAAT Gene: CPS_2237: Microbial collagenase, secreted (EC 3.4.24.3)	Alteromonadales bacterium TW-7	Pseudoalteromonas haloplanktis TAC125	* Pseudoalteromonas tunicata D2 Site: position = -179 score = 4.86675 sequence = ATTGTATACATT Site: position = -132 score = 4.16514 sequence = AATGTAAACAAT Gene: PTD2_04421: Microbial collagenase, secreted (EC 3.4.24.3)	Idiomarina baltica OS145	Idiomarina loihiensis L2TR	Microbial collagenase, secreted (EC 3.4.24.3)

CRON 5.
hypO	Pseudoalteromonas atlantica T6c	Alteromonas macleodii 'Deep ecotype'	Glaciecola sp. HTCC2999	Colwellia psychrerythraea 34H Gene: CPS_1447: D-amino acid dehydrogenase (EC 1.4.99.1) family protein in hydroxy-L-proline catabolic cluster	* Alteromonadales bacterium TW-7 Site: position = -211 score = 5.32149 sequence = ATTGTATACAAT Gene: ATW7_13123: D-amino acid dehydrogenase (EC 1.4.99.1) family protein in hydroxy-L-proline catabolic cluster	Pseudoalteromonas haloplanktis TAC125	* Pseudoalteromonas tunicata D2 Site: position = 6 score = 5.01168 sequence = ATTGTATGCAAT Gene: PTD2_14392: D-amino acid dehydrogenase (EC 1.4.99.1) family protein in hydroxy-L-proline catabolic cluster	Idiomarina baltica OS145	Idiomarina loihiensis L2TR	D-amino acid dehydrogenase (EC 1.4.99.1) family protein in hydroxy-L-proline catabolic cluster
prdP	Pseudoalteromonas atlantica T6c Gene: Patl_3777: Proline dipeptidase	Alteromonas macleodii 'Deep ecotype' Gene: MADE_01522: Proline dipeptidase	Glaciecola sp. HTCC2999	* Colwellia psychrerythraea 34H Site: position = -115 score = 4.69346 sequence = AGTGTATACAAT Gene: CPS_1459: Proline dipeptidase	2 Alteromonadales bacterium TW-7 Gene: ATW7_13128: Proline dipeptidase Gene: ATW7_02617: Proline dipeptidase	Pseudoalteromonas haloplanktis TAC125 Gene: PSHAb0215: Proline dipeptidase	* Pseudoalteromonas tunicata D2 Site: position = -144 score = 3.66632 sequence = ATGTTATACAGT Site: position = -128 score = 3.95981 sequence = ATTGTATAATTT Site: position = -24 score = 5.01168 sequence = ATTGCATACAAT Gene: PTD2_03171: Proline dipeptidase	Idiomarina baltica OS145 Gene: OS145_00640: Proline dipeptidase	Idiomarina loihiensis L2TR Gene: IL0630: Proline dipeptidase	Proline dipeptidase

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog HypR - Alteromonadales

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --