Regulog HypR - Enterobacteriales
| Regulator type: | Transcription factor |
| Regulator family: | GntR/Others |
| Regulation mode: | activator (repressor) |
| Biological process: | Proline and 4-hydrohyproline utilization |
| Effector: | Proline; 4-hydroxyproline |
| Phylum: | Proteobacteria/gamma |
| Visualization: | |
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Allows to visualize regulog content in the context of metabolic pathways |
Member of regulog collections
- By taxonomy - Enterobacteriales
- By trascription factor - HypR
- By TF family - GntR/Others
- By effector - Proline
- By effector - 4-hydroxyproline
- By pathway - Proline and 4-hydrohyproline utilization
| Genome | Genes | Operons |
|---|---|---|
| Escherichia coli str. K-12 substr. MG1655 | ||
| Salmonella typhimurium LT2 | ||
| Citrobacter koseri ATCC BAA-895 | ||
| Klebsiella pneumoniae subsp. pneumoniae MGH 78578 | ||
| Enterobacter sp. 638 | ||
| Erwinia amylovora ATCC 49946 | 9 | 1 |
| Yersinia pestis KIM | ||
| Serratia proteamaculans 568 | ||
| Erwinia carotovora subsp. atroseptica SCRI1043 | ||
| Edwardsiella tarda EIB202 | ||
| Proteus mirabilis HI4320 | ||
| Photorhabdus luminescens subsp. laumondii TTO1 |
| Genes | Function | ||||||||||||
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| CRON 1. | |||||||||||||
| COG531 (PotE) |
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Erwinia amylovora ATCC 49946 Site: position = -81 score = 3.93499 sequence = ATCGTATACGAT Gene: EAM_2489: Putative proline/hydroxyproline permease, PotE family |
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Gene: Spro_1836: Putative proline/hydroxyproline permease, PotE family |
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Gene: plu2247: Putative proline/hydroxyproline permease, PotE family |
Putative proline/hydroxyproline permease, PotE family |
| hypD |
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Gene: EAM_2488: 1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) # predicted |
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Gene: Spro_1838: 1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) # predicted |
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Gene: plu2245: 1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) # predicted |
1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) # predicted |
| hypR |
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Gene: EAM_2487: Predicted regulator for proline and hydrohyproline utilization, GntR family |
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Predicted regulator for proline and hydrohyproline utilization, GntR family |
| hypE |
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Gene: EAM_2486: Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8) |
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Gene: Spro_1840: Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8) |
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Gene: plu2243: Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8) |
Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8) |
| hypO |
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Gene: EAM_2485: D-amino acid dehydrogenase (EC 1.4.99.1) family protein in hydroxy-L-proline catabolic cluster |
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Gene: Spro_1841: D-amino acid dehydrogenase (EC 1.4.99.1) family protein in hydroxy-L-proline catabolic cluster |
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Gene: plu2242: D-amino acid dehydrogenase (EC 1.4.99.1) family protein in hydroxy-L-proline catabolic cluster |
D-amino acid dehydrogenase (EC 1.4.99.1) family protein in hydroxy-L-proline catabolic cluster |
| EAM_2484 |
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Gene: EAM_2484: Oxidase |
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Gene: Spro_1842: Oxidase |
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Gene: plu2241: Oxidase |
Oxidase |
| COG446 (HcaD) |
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Gene: EAM_2483: Putative oxidoreductase in 4-hydroxyproline catabolic gene cluster |
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Gene: Spro_1843: Putative oxidoreductase in 4-hydroxyproline catabolic gene cluster |
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Gene: plu2240: Putative oxidoreductase in 4-hydroxyproline catabolic gene cluster |
Putative oxidoreductase in 4-hydroxyproline catabolic gene cluster |
| hypH |
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Gene: EAM_2482: Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) # hydroxy-L-proline-inducible |
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Gene: Spro_1837: Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) # hydroxy-L-proline-inducible |
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Gene: plu2246: Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) # hydroxy-L-proline-inducible |
Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) # hydroxy-L-proline-inducible |
| hypS |
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Gene: EAM_2481: Putative L-lactate/Malate dehydrogenase |
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Gene: Spro_1835: Putative L-lactate/Malate dehydrogenase |
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Putative L-lactate/Malate dehydrogenase |
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
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Regulatory Sites | [ FASTA format ] | DOWNLOAD |