Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Orthologous regulated operons containing COG446 (HcaD) gene

Properties
Regulog: HypR - Enterobacteriales
Regulator type: Transcription factor
Regulator family: GntR/Others
Regulation mode: activator (repressor)
Biological process: Proline and 4-hydrohyproline utilization
Effector: Proline; 4-hydroxyproline
Phylum: Proteobacteria/gamma
Built upon 1 sites [see more]
Orthologous operons
Operon Position Score Sequence Locus Tag of the First Gene
Erwinia amylovora ATCC 49946
Position: -81
Score: 3.93499
Sequence: ATCGTATACGAT
Locus tag: EAM_2489
Name: COG531 (PotE)
Funciton: Putative proline/hydroxyproline permease, PotE family
Locus tag: EAM_2488
Name: hypD
Funciton: 1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) # predicted
Locus tag: EAM_2487
Name: hypR
Funciton: Predicted regulator for proline and hydrohyproline utilization, GntR family
Locus tag: EAM_2486
Name: hypE
Funciton: Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8)
Locus tag: EAM_2485
Name: hypO
Funciton: D-amino acid dehydrogenase (EC 1.4.99.1) family protein in hydroxy-L-proline catabolic cluster
Locus tag: EAM_2484
Name: EAM_2484
Funciton: Oxidase
Locus tag: EAM_2483
Name: COG446 (HcaD)
Funciton: Putative oxidoreductase in 4-hydroxyproline catabolic gene cluster
Locus tag: EAM_2482
Name: hypH
Funciton: Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) # hydroxy-L-proline-inducible
Locus tag: EAM_2481
Name: hypS
Funciton: Putative L-lactate/Malate dehydrogenase
COG531 (PotE)-hypD-hypR-hypE-hypO-EAM_2484-COG446 (HcaD)-hypH-hypS -81 3.9 ATCGTATACGAT EAM_2489