Regulog HypR - Pseudomonadaceae
| Regulator type: | Transcription factor |
| Regulator family: | GntR/Others |
| Regulation mode: | activator (repressor) |
| Biological process: | Proline and 4-hydrohyproline utilization |
| Effector: | Proline; 4-hydroxyproline |
| Phylum: | Proteobacteria/gamma |
| Visualization: | |
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Allows to visualize regulog content in the context of metabolic pathways |
Member of regulog collections
- By taxonomy - Pseudomonadaceae
- By trascription factor - HypR
- By TF family - GntR/Others
- By effector - Proline
- By effector - 4-hydroxyproline
- By pathway - Proline and 4-hydrohyproline utilization
| Genome | Genes | Operons |
|---|---|---|
| Pseudomonas aeruginosa PAO1 | 11 | 3 |
| Pseudomonas entomophila L48 | ||
| Pseudomonas putida KT2440 | ||
| Pseudomonas syringae pv. tomato str. DC3000 | ||
| Pseudomonas fluorescens Pf-5 | ||
| Pseudomonas mendocina ymp | ||
| Pseudomonas stutzeri A1501 | ||
| Azotobacter vinelandii AvOP |
| Genes | Function | ||||||||
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| CRON 1. | |||||||||
| hypM |
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Pseudomonas aeruginosa PAO1 Site: position = -67 score = 3.80123 sequence = ATCGTATACGAA Gene: PA1260: Predicted hydroxyproline ABC transporter, substrate-binding protein |
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Predicted hydroxyproline ABC transporter, substrate-binding protein |
| hypX |
Gene: PA1259: Putative citrate/isocitrate isomerase or aconitase ## predicted from clustering to proline racemase |
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Putative citrate/isocitrate isomerase or aconitase ## predicted from clustering to proline racemase |
| hypN |
Gene: PA1258: Predicted hydroxyproline ABC transporter, permease protein |
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Predicted hydroxyproline ABC transporter, permease protein |
| hypP |
Gene: PA1257: Predicted hydroxyproline ABC transporter, permease protein |
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Predicted hydroxyproline ABC transporter, permease protein |
| hypQ |
Gene: PA1256: Predicted hydroxyproline ABC transporter, ATP-binding protein |
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Predicted hydroxyproline ABC transporter, ATP-binding protein |
| hypY |
Gene: PA1255: Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8) |
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Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8) |
| CRON 2. | |||||||||
| hypR |
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Pseudomonas aeruginosa PAO1 Site: position = -61 score = 4.49449 sequence = TTCGTATACAAT Gene: PA1269: Predicted regulator for proline and hydrohyproline utilization, GntR family |
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Predicted regulator for proline and hydrohyproline utilization, GntR family |
| hypE |
Gene: PA1268: Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8) |
Gene: PSEEN4050: Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8) |
Gene: PP1258: Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8) |
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Gene: PFL_1412: Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8) |
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Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8) |
| hypO |
Gene: PA1267: D-amino acid dehydrogenase (EC 1.4.99.1) family protein in hydroxy-L-proline catabolic cluster |
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D-amino acid dehydrogenase (EC 1.4.99.1) family protein in hydroxy-L-proline catabolic cluster |
| CRON 3. | |||||||||
| hypD |
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Pseudomonas aeruginosa PAO1 Site: position = -32 score = 3.66748 sequence = TTCGTATACGAA Gene: PA1254: 1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) # predicted |
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Gene: PFL_1413: 1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) # predicted |
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1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) # predicted |
| hypH |
Gene: PA1253: Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) # hydroxy-L-proline-inducible |
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Gene: PP2585: Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) # hydroxy-L-proline-inducible |
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Gene: PFL_1415: Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) # hydroxy-L-proline-inducible |
Gene: Pmen_0227: Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) # hydroxy-L-proline-inducible |
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Ketoglutarate semialdehyde dehydrogenase (EC 1.2.1.26) # hydroxy-L-proline-inducible |
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
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Regulatory Sites | [ FASTA format ] | DOWNLOAD |