Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of HypR in Agrobacterium tumefaciens str. C58 (Cereon)

Properties
Regulator type: Transcription factor
TF locus tag: Atu4674
Regulator family: GntR/Others
Regulation mode: activator (repressor)
Biological process: Proline and 4-hydrohyproline utilization
Effector: Proline
Regulog: HypR - Rhizobiales
Statistics of regulated genes:
- Genes 10
- Operons 4
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 18 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -232
Score: 4.2
Sequence: ATGAGTATACAAAA
Position: -52
Score: 3.5
Sequence: CTTTGTATACTTTA
Position: -41
Score: 3.7
Sequence: TTATGTATTCAAAA
Locus tag: Atu4676
Name: hypS
Funciton: Putative L-lactate/Malate dehydrogenase
hypS
Putative L-lactate/Malate dehydrogenase

Position: -100
Score: 4.2
Sequence: TTTTGTATACTCAT
Locus tag: Atu4678
Name: hypM
Funciton: Predicted hydroxyproline ABC transporter, substrate-binding protein
Locus tag: Atu4679
Name: hypN
Funciton: Predicted hydroxyproline ABC transporter, permease protein
Locus tag: Atu4680
Name: hypP
Funciton: Predicted hydroxyproline ABC transporter, permease protein
Locus tag: Atu4681
Name: hypQ
Funciton: Predicted hydroxyproline ABC transporter, ATP-binding protein
Locus tag: Atu4682
Name: hypO
Funciton: D-amino acid dehydrogenase (EC 1.4.99.1) family protein in hydroxy-L-proline catabolic cluster
Locus tag: Atu4683
Name: hypX
Funciton: Putative citrate/isocitrate isomerase or aconitase ## predicted from clustering to proline racemase
Locus tag: Atu4684
Name: hypY
Funciton: Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8), possible pseudogene, inactive
hypM
Predicted hydroxyproline ABC transporter, substrate-binding protein
hypN
Predicted hydroxyproline ABC transporter, permease protein
hypP
Predicted hydroxyproline ABC transporter, permease protein
hypQ
Predicted hydroxyproline ABC transporter, ATP-binding protein
hypO
D-amino acid dehydrogenase (EC 1.4.99.1) family protein in hydroxy-L-proline catabolic cluster
hypX
Putative citrate/isocitrate isomerase or aconitase ## predicted from clustering to proline racemase
hypY
Proline racemase /4-hydroxyproline epimerase (EC 5.1.1.8), possible pseudogene, inactive

Position: -25
Score: 4.7
Sequence: TTATGTCGACAAGA
Locus tag: Atu4674
Name: hypR
Funciton: Predicted regulator for proline and hydrohyproline utilization, GntR family
hypR
Predicted regulator for proline and hydrohyproline utilization, GntR family

Position: -99
Score: 5.1
Sequence: TCTTGTCGACAAAT
Locus tag: Atu4675
Name: hypD
Funciton: 1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) # predicted
hypD
1-pyrroline-4-hydroxy-2-carboxylate deaminase (EC 3.5.4.22) # predicted
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