Regulog SdhR - Ralstonia

Properties
Regulator type:	Transcription factor
Regulator family:	GntR/Others
Regulation mode:
Biological process:	Tricarboxylic acid cycle
Effector:
Phylum:	Proteobacteria/Beta
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 41 sites [see more]

Member of regulog collections

By taxonomy - Ralstonia
By TF family - GntR/Others
By pathway - Tricarboxylic acid cycle

Statistics of regulated genes
Genome	Genes	Operons
Cupriavidus taiwanensis	12	6
Ralstonia eutropha H16	14	6
Ralstonia eutropha JMP134	13	5
Ralstonia metallidurans CH34	15	7
Ralstonia pickettii 12J	16	8
Ralstonia solanacearum GMI1000	12	4

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes							Function

CRON 1.
mdh	* Cupriavidus taiwanensis Site: position = -360 score = 7.89101 sequence = TCTTATGTCTTATATAAGACATATGA Gene: RALTA_A2133: Malate dehydrogenase (EC 1.1.1.37)	* Ralstonia eutropha H16 Site: position = -379 score = 7.89101 sequence = TCTTATGTCTTATATAAGACATATGA Gene: H16_A2634: Malate dehydrogenase (EC 1.1.1.37)	* Ralstonia eutropha JMP134 Site: position = -327 score = 7.89101 sequence = TCTTATGTCTTATATAAGACATATGA Gene: Reut_A2327: Malate dehydrogenase (EC 1.1.1.37)	* Ralstonia metallidurans CH34 Site: position = -339 score = 7.89101 sequence = TCTTATGTCTTATATAAGACATATGA Gene: Rmet_2489: Malate dehydrogenase (EC 1.1.1.37)	* Ralstonia pickettii 12J Site: position = -298 score = 7.66319 sequence = TCTTATGTCTTATATAAGACAGAAGA Gene: Rpic_2153: Malate dehydrogenase (EC 1.1.1.37)	* Ralstonia solanacearum GMI1000 Site: position = -296 score = 7.66319 sequence = TCTTATGTCTTATATAAGACAGAAGA Gene: RSc1998: Malate dehydrogenase (EC 1.1.1.37)	Malate dehydrogenase (EC 1.1.1.37)
citE	Cupriavidus taiwanensis Gene: RALTA_A2134: Citrate lyase beta chain (EC 4.1.3.6)	Ralstonia eutropha H16 Gene: H16_A2635: Citrate lyase beta chain (EC 4.1.3.6)	Ralstonia eutropha JMP134 Gene: Reut_A2328: Citrate lyase beta chain (EC 4.1.3.6)	Ralstonia metallidurans CH34 Gene: Rmet_2490: Citrate lyase beta chain (EC 4.1.3.6)	Ralstonia pickettii 12J Gene: Rpic_2154: Citrate lyase beta chain (EC 4.1.3.6)	Ralstonia solanacearum GMI1000 Gene: RS03567: Citrate lyase beta chain (EC 4.1.3.6)	Citrate lyase beta chain (EC 4.1.3.6)
prpB2	Cupriavidus taiwanensis	Ralstonia eutropha H16	Ralstonia eutropha JMP134	Ralstonia metallidurans CH34	Ralstonia pickettii 12J Gene: Rpic_2155: 2-methylisocitrate lyase (EC 4.1.3.30)	Ralstonia solanacearum GMI1000 Gene: RSc2000: 2-methylisocitrate lyase (EC 4.1.3.30)	2-methylisocitrate lyase (EC 4.1.3.30)
prpC2	Cupriavidus taiwanensis Gene: RALTA_A2135: 2-methylcitrate synthase (EC 2.3.3.5)	Ralstonia eutropha H16 Gene: H16_A2636: 2-methylcitrate synthase (EC 2.3.3.5)	Ralstonia eutropha JMP134 Gene: Reut_A2329: 2-methylcitrate synthase (EC 2.3.3.5)	Ralstonia metallidurans CH34	Ralstonia pickettii 12J	Ralstonia solanacearum GMI1000	2-methylcitrate synthase (EC 2.3.3.5)

CRON 2.
aceA2	* Cupriavidus taiwanensis Site: position = -132 score = 7.4564 sequence = TCTTATGTCTTATATAAGACATAACC Gene: RALTA_B0267: Isocitrate lyase (EC 4.1.3.1)	* Ralstonia eutropha H16 Site: position = -132 score = 6.08122 sequence = TCTTATGTCTTATATAAGACTTTGCC Gene: H16_A2211: Isocitrate lyase (EC 4.1.3.1)	* Ralstonia eutropha JMP134 Site: position = -134 score = 6.50745 sequence = TCTTATGTCTTATATAAGACTGACGC Gene: Reut_A0384: Isocitrate lyase (EC 4.1.3.1)	* Ralstonia metallidurans CH34 Site: position = -134 score = 6.08122 sequence = TCTTATGTCTTATATAAGACCTTGCC Gene: Rmet_4737: Isocitrate lyase (EC 4.1.3.1)	2 Ralstonia pickettii 12J* Site: position = -135 score = 6.19258 sequence = TCTTATGTCTTATATAAGACCTTGCT Gene: Rpic_0542: Isocitrate lyase (EC 4.1.3.1) Site: position = -135 score = 6.19258 sequence = TCTTATGTCTTATATAAGACCTTGCT Gene: Rpic_4801: Isocitrate lyase (EC 4.1.3.1)	Ralstonia solanacearum GMI1000	Isocitrate lyase (EC 4.1.3.1)

CRON 3.
acnB	* Cupriavidus taiwanensis Site: position = -22 score = 5.81286 sequence = TCTTATATAAGATATAAGACATTTGA Site: position = -29 score = 6.2371 sequence = GATGAACTCTTATATAAGATATAAGA Gene: RALTA_B0366: Aconitate hydratase 2 (EC 4.2.1.3)	* Ralstonia eutropha H16 Site: position = -104 score = 6.55779 sequence = TCTTCACTCTTATATAAGATATAAGA Site: position = -97 score = 5.81286 sequence = TCTTATATAAGATATAAGACATTTGA Gene: H16_B0568: Aconitate hydratase 2 (EC 4.2.1.3)	Ralstonia eutropha JMP134 Gene: Reut_B3464: Aconitate hydratase 2 (EC 4.2.1.3)	* Ralstonia metallidurans CH34 Site: position = -130 score = 5.81286 sequence = TCTTATATAAGATATAAGACATTTGA Site: position = -137 score = 6.05368 sequence = TATCGACTCTTATATAAGATATAAGA Gene: Rmet_5296: Aconitate hydratase 2 (EC 4.2.1.3)	2 Ralstonia pickettii 12J* Site: position = -127 score = 5.81286 sequence = TCTTATATAAGATATAAGACATTTGA Site: position = -134 score = 6.18902 sequence = GTTTAACTCTTATATAAGATATAAGA Gene: Rpic_4479: Aconitate hydratase 2 (EC 4.2.1.3) Site: position = -128 score = 5.81286 sequence = TCTTATATAAGATATAAGACATTTGA Site: position = -135 score = 6.16356 sequence = GCTTGACTCTTATATAAGATATAAGA Gene: Rpic_4553: Aconitate hydratase 2 (EC 4.2.1.3)	Ralstonia solanacearum GMI1000 Gene: RSp0332: Aconitate hydratase 2 (EC 4.2.1.3)	Aconitate hydratase 2 (EC 4.2.1.3)

CRON 4.
icd	* Cupriavidus taiwanensis Site: position = -168 score = 6.32163 sequence = TCTTGTGTCTTATATAAGACTGAATC Gene: RALTA_A2531: Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)	* Ralstonia eutropha H16 Site: position = -168 score = 6.26805 sequence = TCTTGTGTCTTATATAAGACTGAAGG Gene: H16_A3056: Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)	* Ralstonia eutropha JMP134 Site: position = -158 score = 5.82186 sequence = TCTTGTGTCTTATATAAGACTGAAAG Gene: Reut_A2756: Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)	* Ralstonia metallidurans CH34 Site: position = -167 score = 5.21196 sequence = TCTTGGGTCTTATATAAGACTGACAT Gene: Rmet_2895: Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)	* Ralstonia pickettii 12J Site: position = -194 score = 5.4928 sequence = TCTTGTGTCTTATATAAGAGTTGCGG Gene: Rpic_2752: Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)	* Ralstonia solanacearum GMI1000 Site: position = -168 score = 5.4928 sequence = TCTTGTGTCTTATATAAGAGTTGCGG Gene: RSc2490: Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)	Isocitrate dehydrogenase [NADP] (EC 1.1.1.42)

CRON 5.
tam	Cupriavidus taiwanensis Gene: RALTA_A3215: Trans-aconitate 2-methyltransferase (EC 2.1.1.144)	Ralstonia eutropha H16 Gene: H16_A0107: Trans-aconitate 2-methyltransferase (EC 2.1.1.144)	Ralstonia eutropha JMP134 Gene: Reut_A3459: Trans-aconitate 2-methyltransferase (EC 2.1.1.144)	* Ralstonia metallidurans CH34 Site: position = -56 score = 6.25418 sequence = TCTTATATCTTATATAAGACTAGAAT Gene: Rmet_3612: Trans-aconitate 2-methyltransferase (EC 2.1.1.144)	Ralstonia pickettii 12J Gene: Rpic_3620: Trans-aconitate 2-methyltransferase (EC 2.1.1.144)	Ralstonia solanacearum GMI1000	Trans-aconitate 2-methyltransferase (EC 2.1.1.144)

CRON 6.
aceA	* Cupriavidus taiwanensis Site: position = -132 score = 5.35941 sequence = TCTACACTCTTATATAAGACACAGGA Gene: RALTA_A1766: Isocitrate lyase (EC 4.1.3.1)	* Ralstonia eutropha H16 Site: position = -128 score = 5.22302 sequence = TCTACACTCTTATATAAGACTCATGA Gene: H16_A2227: Isocitrate lyase (EC 4.1.3.1)	* Ralstonia eutropha JMP134 Site: position = -124 score = 5.43954 sequence = CCTACACTCTTATATAAGACAAATGA Gene: Reut_A1961: Isocitrate lyase (EC 4.1.3.1)	* Ralstonia metallidurans CH34 Site: position = -129 score = 5.71204 sequence = TCTACACTCTTATATAAGACACATGA Gene: Rmet_1385: Isocitrate lyase (EC 4.1.3.1)	* Ralstonia pickettii 12J Site: position = -127 score = 6.18368 sequence = TCTACACTCTTATATAAGACATATGA Gene: Rpic_1232: Isocitrate lyase (EC 4.1.3.1)	* Ralstonia solanacearum GMI1000 Site: position = -104 score = 6.18368 sequence = TCTACACTCTTATATAAGACATATGA Gene: RSc1358: Isocitrate lyase (EC 4.1.3.1)	Isocitrate lyase (EC 4.1.3.1)

CRON 7.
sdhR	* Cupriavidus taiwanensis Site: position = -254 score = 7.89101 sequence = TCATATGTCTTATATAAGACATAAGA Gene: RALTA_A2132: Transcriptional regulator of TCA cycle, GntR family	* Ralstonia eutropha H16 Site: position = -77 score = 7.89101 sequence = TCATATGTCTTATATAAGACATAAGA Gene: H16_A2633: Transcriptional regulator of TCA cycle, GntR family	* Ralstonia eutropha JMP134 Site: position = -77 score = 7.89101 sequence = TCATATGTCTTATATAAGACATAAGA Gene: Reut_A2326: Transcriptional regulator of TCA cycle, GntR family	* Ralstonia metallidurans CH34 Site: position = -78 score = 7.89101 sequence = TCATATGTCTTATATAAGACATAAGA Gene: Rmet_2488: Transcriptional regulator of TCA cycle, GntR family	* Ralstonia pickettii 12J Site: position = -80 score = 7.66319 sequence = TCTTCTGTCTTATATAAGACATAAGA Gene: Rpic_2152: Transcriptional regulator of TCA cycle, GntR family	* Ralstonia solanacearum GMI1000 Site: position = -62 score = 7.66319 sequence = TCTTCTGTCTTATATAAGACATAAGA Gene: RS03565: Transcriptional regulator of TCA cycle, GntR family	Transcriptional regulator of TCA cycle, GntR family
Rmet_2487	Cupriavidus taiwanensis	Ralstonia eutropha H16	Ralstonia eutropha JMP134	Ralstonia metallidurans CH34 Gene: Rmet_2487: hypothetical protein	Ralstonia pickettii 12J	Ralstonia solanacearum GMI1000	hypothetical protein
sdhC	Cupriavidus taiwanensis Gene: RALTA_A2131: Succinate dehydrogenase cytochrome b-556 subunit	Ralstonia eutropha H16 Gene: H16_A2632: Succinate dehydrogenase cytochrome b-556 subunit	Ralstonia eutropha JMP134 Gene: Reut_A2325: Succinate dehydrogenase cytochrome b-556 subunit	Ralstonia metallidurans CH34 Gene: Rmet_2486: Succinate dehydrogenase cytochrome b-556 subunit	2 Ralstonia pickettii 12J Gene: Rpic_2151: Succinate dehydrogenase cytochrome b-556 subunit Gene: Rpic_4356: Succinate dehydrogenase cytochrome b-556 subunit	Ralstonia solanacearum GMI1000 Gene: RSc1996: Succinate dehydrogenase cytochrome b-556 subunit	Succinate dehydrogenase cytochrome b-556 subunit
sdhD	Cupriavidus taiwanensis Gene: RALTA_A2130: Succinate dehydrogenase hydrophobic membrane anchor protein	Ralstonia eutropha H16 Gene: H16_A2631: Succinate dehydrogenase hydrophobic membrane anchor protein	Ralstonia eutropha JMP134 Gene: Reut_A2324: Succinate dehydrogenase hydrophobic membrane anchor protein	Ralstonia metallidurans CH34 Gene: Rmet_2485: Succinate dehydrogenase hydrophobic membrane anchor protein	2 Ralstonia pickettii 12J Gene: Rpic_2150: Succinate dehydrogenase hydrophobic membrane anchor protein Gene: Rpic_4357: Succinate dehydrogenase hydrophobic membrane anchor protein	Ralstonia solanacearum GMI1000 Gene: RSc1995: Succinate dehydrogenase hydrophobic membrane anchor protein	Succinate dehydrogenase hydrophobic membrane anchor protein
sdhA	Cupriavidus taiwanensis Gene: RALTA_A2129: Succinate dehydrogenase flavoprotein subunit (EC 1.3.99.1)	Ralstonia eutropha H16 Gene: H16_A2630: Succinate dehydrogenase flavoprotein subunit (EC 1.3.99.1)	Ralstonia eutropha JMP134 Gene: Reut_A2323: Succinate dehydrogenase flavoprotein subunit (EC 1.3.99.1)	Ralstonia metallidurans CH34 Gene: Rmet_2484: Succinate dehydrogenase flavoprotein subunit (EC 1.3.99.1)	2 Ralstonia pickettii 12J Gene: Rpic_2149: Succinate dehydrogenase flavoprotein subunit (EC 1.3.99.1) Gene: Rpic_4358: Succinate dehydrogenase flavoprotein subunit (EC 1.3.99.1)	Ralstonia solanacearum GMI1000 Gene: RSc1994: Succinate dehydrogenase flavoprotein subunit (EC 1.3.99.1)	Succinate dehydrogenase flavoprotein subunit (EC 1.3.99.1)
sdhB	Cupriavidus taiwanensis Gene: RALTA_A2128: Succinate dehydrogenase iron-sulfur protein (EC 1.3.99.1)	Ralstonia eutropha H16 Gene: H16_A2629: Succinate dehydrogenase iron-sulfur protein (EC 1.3.99.1)	Ralstonia eutropha JMP134 Gene: Reut_A2322: Succinate dehydrogenase iron-sulfur protein (EC 1.3.99.1)	Ralstonia metallidurans CH34 Gene: Rmet_2483: Succinate dehydrogenase iron-sulfur protein (EC 1.3.99.1)	2 Ralstonia pickettii 12J Gene: Rpic_2148: Succinate dehydrogenase iron-sulfur protein (EC 1.3.99.1) Gene: Rpic_4359: Succinate dehydrogenase iron-sulfur protein (EC 1.3.99.1)	Ralstonia solanacearum GMI1000 Gene: RSc1993: Succinate dehydrogenase iron-sulfur protein (EC 1.3.99.1)	Succinate dehydrogenase iron-sulfur protein (EC 1.3.99.1)
COG2938	Cupriavidus taiwanensis Gene: RALTA_A2127: succinate dehydrogenase iron-sulfur subunit	Ralstonia eutropha H16 Gene: H16_A2628: succinate dehydrogenase iron-sulfur subunit	Ralstonia eutropha JMP134 Gene: Reut_A2321: succinate dehydrogenase iron-sulfur subunit	Ralstonia metallidurans CH34 Gene: Rmet_2482: succinate dehydrogenase iron-sulfur subunit	Ralstonia pickettii 12J Gene: Rpic_2147: succinate dehydrogenase iron-sulfur subunit	Ralstonia solanacearum GMI1000 Gene: RS03560: succinate dehydrogenase iron-sulfur subunit	succinate dehydrogenase iron-sulfur subunit
gltA	Cupriavidus taiwanensis Gene: RALTA_A2126: Citrate synthase (si) (EC 2.3.3.1)	Ralstonia eutropha H16 Gene: H16_A2627: Citrate synthase (si) (EC 2.3.3.1)	Ralstonia eutropha JMP134 Gene: Reut_A2320: Citrate synthase (si) (EC 2.3.3.1)	Ralstonia metallidurans CH34 Gene: Rmet_2481: Citrate synthase (si) (EC 2.3.3.1)	Ralstonia pickettii 12J Gene: Rpic_2146: Citrate synthase (si) (EC 2.3.3.1)	Ralstonia solanacearum GMI1000 Gene: RSc1991: Citrate synthase (si) (EC 2.3.3.1)	Citrate synthase (si) (EC 2.3.3.1)

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog SdhR - Ralstonia

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --