Regulog LldR - Desulfuromonadales

Properties
Regulator type:	Transcription factor
Regulator family:	GntR/Others
Regulation mode:	repressor
Biological process:	Lactate utilization
Effector:	L-lactate
Phylum:	Proteobacteria/delta
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 20 sites [see more]

Member of regulog collections

By taxonomy - Desulfuromonadales
By trascription factor - LldR
By TF family - GntR/Others
By effector - L-lactate
By pathway - Lactate utilization

Statistics of regulated genes
Genome	Genes	Operons
Geobacter metallireducens GS-15
Geobacter sulfurreducens PCA	5	2
Geobacter uraniumreducens Rf4	7	3
Geobacter sp. FRC-32
Geobacter sp. M21	8	2
Geobacter lovleyi SZ
Pelobacter propionicus DSM 2379	6	4
Pelobacter carbinolicus str. DSM 2380
Desulfuromonas acetoxidans DSM 684

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes										Function

CRON 1.
lldP	Geobacter metallireducens GS-15	* Geobacter sulfurreducens PCA Site: position = -126 score = 5.08214 sequence = AGTTGGTATGACAACTA Site: position = -235 score = 5.40064 sequence = AAGTTGTAATACCAACT Gene: GSU1622: L-lactate permease	2 Geobacter uraniumreducens Rf4* Site: position = -233 score = 3.73302 sequence = AAAATGTATAACCACAT Site: position = -125 score = 5.57348 sequence = AATTGGTAATACAACTT Gene: Gura_0154: L-lactate permease Site: position = -195 score = 5.18752 sequence = AAATGGTAATACCAACA Site: position = -303 score = 4.71065 sequence = AAATTGTAATACCATAT Gene: Gura_2200: L-lactate permease	Geobacter sp. FRC-32	* Geobacter sp. M21 Site: position = -276 score = 4.02106 sequence = AATAGATATGACCAAAT Site: position = -168 score = 4.55081 sequence = AATTGGCCTGACCAAAA Gene: GM21_1316: L-lactate permease	Geobacter lovleyi SZ	* Pelobacter propionicus DSM 2379 Site: position = -65 score = 4.75449 sequence = AATTGGTAATGCAAGTT Site: position = -322 score = 3.84834 sequence = AAGTGGTAAGACCTTCG Gene: Ppro_2735: L-lactate permease	Pelobacter carbinolicus str. DSM 2380	Desulfuromonas acetoxidans DSM 684	L-lactate permease
GM21_1317	Geobacter metallireducens GS-15	Geobacter sulfurreducens PCA	Geobacter uraniumreducens Rf4	Geobacter sp. FRC-32	Geobacter sp. M21 Gene: GM21_1317: LrgA family protein	Geobacter lovleyi SZ	Pelobacter propionicus DSM 2379	Pelobacter carbinolicus str. DSM 2380	Desulfuromonas acetoxidans DSM 684	LrgA family protein
GM21_1318	Geobacter metallireducens GS-15	Geobacter sulfurreducens PCA	Geobacter uraniumreducens Rf4	Geobacter sp. FRC-32	Geobacter sp. M21 Gene: GM21_1318: LrgB family protein	Geobacter lovleyi SZ	Pelobacter propionicus DSM 2379	Pelobacter carbinolicus str. DSM 2380	Desulfuromonas acetoxidans DSM 684	LrgB family protein
glcD	Geobacter metallireducens GS-15	Geobacter sulfurreducens PCA Gene: GSU1623: Predicted glycolate dehydrogenase, 2-subunit type (EC 1.1.99.14), iron-sulfur subunit GlcD	Geobacter uraniumreducens Rf4 Gene: Gura_2199: Predicted glycolate dehydrogenase, 2-subunit type (EC 1.1.99.14), iron-sulfur subunit GlcD	Geobacter sp. FRC-32	Geobacter sp. M21 Gene: GM21_1319: Predicted glycolate dehydrogenase, 2-subunit type (EC 1.1.99.14), iron-sulfur subunit GlcD	Geobacter lovleyi SZ	* Pelobacter propionicus DSM 2379 Site: position = -114 score = 5.44953 sequence = AATTGGTAATACAACTA Gene: Ppro_2540: Predicted glycolate dehydrogenase, 2-subunit type (EC 1.1.99.14), iron-sulfur subunit GlcD	Pelobacter carbinolicus str. DSM 2380	Desulfuromonas acetoxidans DSM 684	Predicted glycolate dehydrogenase, 2-subunit type (EC 1.1.99.14), iron-sulfur subunit GlcD
glcF	Geobacter metallireducens GS-15	Geobacter sulfurreducens PCA Gene: GSU1624: Predicted glycolate dehydrogenase, 2-subunit type (EC 1.1.99.14), iron-sulfur subunit GlcF	Geobacter uraniumreducens Rf4 Gene: Gura_2198: Predicted glycolate dehydrogenase, 2-subunit type (EC 1.1.99.14), iron-sulfur subunit GlcF	Geobacter sp. FRC-32	Geobacter sp. M21 Gene: GM21_1320: Predicted glycolate dehydrogenase, 2-subunit type (EC 1.1.99.14), iron-sulfur subunit GlcF	Geobacter lovleyi SZ	Pelobacter propionicus DSM 2379 Gene: Ppro_2541: Predicted glycolate dehydrogenase, 2-subunit type (EC 1.1.99.14), iron-sulfur subunit GlcF	Pelobacter carbinolicus str. DSM 2380	Desulfuromonas acetoxidans DSM 684	Predicted glycolate dehydrogenase, 2-subunit type (EC 1.1.99.14), iron-sulfur subunit GlcF
lldR	Geobacter metallireducens GS-15	Geobacter sulfurreducens PCA Gene: GSU1626: Lactate-responsive regulator LldR, GntR family	2 Geobacter uraniumreducens Rf4 Gene: Gura_0158: Lactate-responsive regulator LldR, GntR family Gene: Gura_2197: Lactate-responsive regulator LldR, GntR family	Geobacter sp. FRC-32	Geobacter sp. M21 Gene: GM21_1321: Lactate-responsive regulator LldR, GntR family	Geobacter lovleyi SZ	* Pelobacter propionicus DSM 2379 Site: position = -158 score = 4.71394 sequence = ATGTGGTATTACAAGTT Gene: Ppro_2670: Lactate-responsive regulator LldR, GntR family	Pelobacter carbinolicus str. DSM 2380	Desulfuromonas acetoxidans DSM 684	Lactate-responsive regulator LldR, GntR family

CRON 2.
lldG	Geobacter metallireducens GS-15	* Geobacter sulfurreducens PCA Site: position = -3 score = 5.08214 sequence = TAGTTGTCATACCAACT Site: position = 106 score = 5.40064 sequence = AGTTGGTATTACAACTT Gene: GSU1621: L-lactate dehydrogenase, hypothetical protein subunit LldG	* Geobacter uraniumreducens Rf4 Site: position = -231 score = 3.73302 sequence = ATGTGGTTATACATTTT Site: position = -339 score = 5.57348 sequence = AAGTTGTATTACCAATT Gene: Gura_0153: L-lactate dehydrogenase, hypothetical protein subunit LldG	Geobacter sp. FRC-32	* Geobacter sp. M21 Site: position = -280 score = 4.55081 sequence = TTTTGGTCAGGCCAATT Site: position = -172 score = 4.02106 sequence = ATTTGGTCATATCTATT Gene: GM21_1315: L-lactate dehydrogenase, hypothetical protein subunit LldG	Geobacter lovleyi SZ	* Pelobacter propionicus DSM 2379 Site: position = 0 score = 4.68032 sequence = ATGTGGTCATACCATCT Site: position = -144 score = 4.93743 sequence = AATTGGTAATACCAGAT Gene: Ppro_3136: L-lactate dehydrogenase, hypothetical protein subunit LldG	Pelobacter carbinolicus str. DSM 2380	Desulfuromonas acetoxidans DSM 684	L-lactate dehydrogenase, hypothetical protein subunit LldG
lldEF	Geobacter metallireducens GS-15	Geobacter sulfurreducens PCA Gene: GSU1620: L-lactate dehydrogenase, Fe-S oxidoreductase subunit LldE / L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit LldF	Geobacter uraniumreducens Rf4 Gene: Gura_0152: L-lactate dehydrogenase, Fe-S oxidoreductase subunit LldE / L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit LldF	Geobacter sp. FRC-32	Geobacter sp. M21 Gene: GM21_1314: L-lactate dehydrogenase, Fe-S oxidoreductase subunit LldE / L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit LldF	Geobacter lovleyi SZ	Pelobacter propionicus DSM 2379 Gene: Ppro_3135: L-lactate dehydrogenase, Fe-S oxidoreductase subunit LldE / L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit LldF	Pelobacter carbinolicus str. DSM 2380	Desulfuromonas acetoxidans DSM 684	L-lactate dehydrogenase, Fe-S oxidoreductase subunit LldE / L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit LldF

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

Export
	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog LldR - Desulfuromonadales

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --