Regulog LldR - Micrococcineae

Properties
Regulator type:	Transcription factor
Regulator family:	GntR/Others
Regulation mode:
Biological process:	Lactate utilization
Effector:	L-lactate
Phylum:	Actinobacteria
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 25 sites [see more]

Member of regulog collections

By taxonomy - Micrococcineae
By TF family - GntR/Others
By effector - L-lactate
By pathway - Lactate utilization

Statistics of regulated genes
Genome	Genes	Operons
Arthrobacter aurescens TC1	2	2
Arthrobacter chlorophenolicus A6
Arthrobacter sp. FB24	2	2
Beutenbergia cavernae DSM 12333
Brachybacterium faecium DSM 4810	2	2
Brevibacterium linens BL2	7	4
Clavibacter michiganensis subsp. michiganensis NCPPB 382
Janibacter sp. HTCC2649
Jonesia denitrificans DSM 20603	1	1
Kocuria rhizophila DC2201	5	2
Kytococcus sedentarius DSM 20547
Leifsonia xyli subsp. xyli str. CTCB07
Renibacterium salmoninarum ATCC 33209	2	2
Tropheryma whipplei str. Twist

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes															Function

CRON 1.
lldP2	Arthrobacter aurescens TC1	Arthrobacter chlorophenolicus A6	Arthrobacter sp. FB24	Beutenbergia cavernae DSM 12333	Brachybacterium faecium DSM 4810	Brevibacterium linens BL2	Clavibacter michiganensis subsp. michiganensis NCPPB 382	Janibacter sp. HTCC2649	Jonesia denitrificans DSM 20603	* Kocuria rhizophila DC2201 Site: position = -273 score = 4.28692 sequence = TGTGGCCAGACCAGG Site: position = -132 score = 5.60343 sequence = TGTGGTCGGACCACT Site: position = -118 score = 5.79586 sequence = TGTGGTCTGACCACT Gene: KRH_04350: L-lactate permease	Kytococcus sedentarius DSM 20547	Leifsonia xyli subsp. xyli str. CTCB07	Renibacterium salmoninarum ATCC 33209	Tropheryma whipplei str. Twist	L-lactate permease
lldR	* Arthrobacter aurescens TC1 Site: position = -57 score = 5.96271 sequence = TGTGGTCTAACCACA Site: position = -32 score = 5.77028 sequence = TGTGGTTGGACCACA Gene: AAur_3323: Lactate-responsive regulator LldR in Actinobacteria, GntR family	Arthrobacter chlorophenolicus A6	* Arthrobacter sp. FB24 Site: position = -24 score = 5.96271 sequence = TGTGGTCTAACCACA Site: position = 1 score = 5.77028 sequence = TGTGGTCCAACCACA Gene: Arth_3342: Lactate-responsive regulator LldR in Actinobacteria, GntR family	Beutenbergia cavernae DSM 12333	* Brachybacterium faecium DSM 4810 Site: position = -147 score = 6.19742 sequence = TGTGGTCAGACCACA Gene: Bfae_12010: Lactate-responsive regulator LldR in Actinobacteria, GntR family	2 Brevibacterium linens BL2* Gene: BlinB01002688: Lactate-responsive regulator LldR in Actinobacteria, GntR family Site: position = -119 score = 4.91688 sequence = TGTGGTCAGACCTTA Gene: BlinB01001218: Lactate-responsive regulator LldR in Actinobacteria, GntR family	Clavibacter michiganensis subsp. michiganensis NCPPB 382	Janibacter sp. HTCC2649	* Jonesia denitrificans DSM 20603 Site: position = -52 score = 5.55324 sequence = TGTGGCCTGACCACA Gene: Jden_0453: Lactate-responsive regulator LldR in Actinobacteria, GntR family	2 Kocuria rhizophila DC2201 Gene: KRH_04840: Lactate-responsive regulator LldR in Actinobacteria, GntR family Gene: KRH_04340: Lactate-responsive regulator LldR in Actinobacteria, GntR family	Kytococcus sedentarius DSM 20547	Leifsonia xyli subsp. xyli str. CTCB07	* Renibacterium salmoninarum ATCC 33209 Site: position = -36 score = 5.1409 sequence = TGTGGTTGGACCATA Site: position = 1 score = 5.55348 sequence = TGTGGTCCTACCACA Gene: RSal33209_2721: Lactate-responsive regulator LldR in Actinobacteria, GntR family	Tropheryma whipplei str. Twist	Lactate-responsive regulator LldR in Actinobacteria, GntR family

CRON 2.
lldP	Arthrobacter aurescens TC1	Arthrobacter chlorophenolicus A6	Arthrobacter sp. FB24	Beutenbergia cavernae DSM 12333	Brachybacterium faecium DSM 4810	* Brevibacterium linens BL2 Site: position = -42 score = 5.79586 sequence = AGTGGTCTGACCACA Gene: BlinB01001150: L-lactate permease	Clavibacter michiganensis subsp. michiganensis NCPPB 382	Janibacter sp. HTCC2649	Jonesia denitrificans DSM 20603	Kocuria rhizophila DC2201	Kytococcus sedentarius DSM 20547	Leifsonia xyli subsp. xyli str. CTCB07	Renibacterium salmoninarum ATCC 33209	Tropheryma whipplei str. Twist	L-lactate permease
lldD	* Arthrobacter aurescens TC1 Site: position = -136 score = 5.77028 sequence = TGTGGTCCAACCACA Site: position = -111 score = 5.96271 sequence = TGTGGTTAGACCACA Gene: AAur_3324: L-lactate dehydrogenase (EC 1.1.2.3)	Arthrobacter chlorophenolicus A6 Gene: Achl_3141: L-lactate dehydrogenase (EC 1.1.2.3)	* Arthrobacter sp. FB24 Site: position = -101 score = 5.77028 sequence = TGTGGTTGGACCACA Site: position = -76 score = 5.96271 sequence = TGTGGTTAGACCACA Gene: Arth_3343: L-lactate dehydrogenase (EC 1.1.2.3)	Beutenbergia cavernae DSM 12333 Gene: Bcav_3293: L-lactate dehydrogenase (EC 1.1.2.3)	* Brachybacterium faecium DSM 4810 Site: position = -63 score = 6.19742 sequence = TGTGGTCTGACCACA Gene: Bfae_12000: L-lactate dehydrogenase (EC 1.1.2.3)	2 Brevibacterium linens BL2* Gene: BlinB01001149: L-lactate dehydrogenase (EC 1.1.2.3) Site: position = 27 score = 4.08837 sequence = TTCGGTCTGCCCAGA Gene: BlinB01002179: L-lactate dehydrogenase (EC 1.1.2.3)	Clavibacter michiganensis subsp. michiganensis NCPPB 382	Janibacter sp. HTCC2649	Jonesia denitrificans DSM 20603	Kocuria rhizophila DC2201 Gene: KRH_12300: L-lactate dehydrogenase (EC 1.1.2.3)	Kytococcus sedentarius DSM 20547 Gene: Ksed_03020: L-lactate dehydrogenase (EC 1.1.2.3)	Leifsonia xyli subsp. xyli str. CTCB07	* Renibacterium salmoninarum ATCC 33209 Site: position = -24 score = 5.55348 sequence = TGTGGTAGGACCACA Site: position = 13 score = 5.1409 sequence = TATGGTCCAACCACA Gene: RSal33209_2722: L-lactate dehydrogenase (EC 1.1.2.3)	Tropheryma whipplei str. Twist	L-lactate dehydrogenase (EC 1.1.2.3)

CRON 3.
lldE	Arthrobacter aurescens TC1	Arthrobacter chlorophenolicus A6 Gene: Achl_3104: L-lactate dehydrogenase, Fe-S oxidoreductase subunit LldE	Arthrobacter sp. FB24	Beutenbergia cavernae DSM 12333	Brachybacterium faecium DSM 4810 Gene: Bfae_12950: L-lactate dehydrogenase, Fe-S oxidoreductase subunit LldE	* Brevibacterium linens BL2 Site: position = -118 score = 4.91688 sequence = TAAGGTCTGACCACA Gene: BlinB01001219: L-lactate dehydrogenase, Fe-S oxidoreductase subunit LldE	Clavibacter michiganensis subsp. michiganensis NCPPB 382	Janibacter sp. HTCC2649 Gene: JNB_14078: L-lactate dehydrogenase, Fe-S oxidoreductase subunit LldE	Jonesia denitrificans DSM 20603	* Kocuria rhizophila DC2201 Site: position = -223 score = 5.79586 sequence = AGTGGTCAGACCACA Site: position = -209 score = 5.60343 sequence = AGTGGTCCGACCACA Site: position = -68 score = 4.28692 sequence = CCTGGTCTGGCCACA Gene: KRH_04360: L-lactate dehydrogenase, Fe-S oxidoreductase subunit LldE	Kytococcus sedentarius DSM 20547 Gene: Ksed_04070: L-lactate dehydrogenase, Fe-S oxidoreductase subunit LldE	Leifsonia xyli subsp. xyli str. CTCB07	Renibacterium salmoninarum ATCC 33209	Tropheryma whipplei str. Twist	L-lactate dehydrogenase, Fe-S oxidoreductase subunit LldE
lldF	Arthrobacter aurescens TC1	Arthrobacter chlorophenolicus A6 Gene: Achl_3103: L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit LldF	Arthrobacter sp. FB24	Beutenbergia cavernae DSM 12333	Brachybacterium faecium DSM 4810 Gene: Bfae_12940: L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit LldF	Brevibacterium linens BL2 Gene: BlinB01001220: L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit LldF	Clavibacter michiganensis subsp. michiganensis NCPPB 382	Janibacter sp. HTCC2649 Gene: JNB_14083: L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit LldF	Jonesia denitrificans DSM 20603	Kocuria rhizophila DC2201 Gene: KRH_04370: L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit LldF	Kytococcus sedentarius DSM 20547 Gene: Ksed_04080: L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit LldF	Leifsonia xyli subsp. xyli str. CTCB07	Renibacterium salmoninarum ATCC 33209	Tropheryma whipplei str. Twist	L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit LldF
lldG	Arthrobacter aurescens TC1	Arthrobacter chlorophenolicus A6 Gene: Achl_3102: L-lactate dehydrogenase, subunit LldG	Arthrobacter sp. FB24	Beutenbergia cavernae DSM 12333	Brachybacterium faecium DSM 4810 Gene: Bfae_12930: L-lactate dehydrogenase, subunit LldG	Brevibacterium linens BL2 Gene: BlinB01001221: L-lactate dehydrogenase, subunit LldG	Clavibacter michiganensis subsp. michiganensis NCPPB 382	Janibacter sp. HTCC2649 Gene: JNB_14088: L-lactate dehydrogenase, subunit LldG	Jonesia denitrificans DSM 20603	Kocuria rhizophila DC2201 Gene: KRH_04380: L-lactate dehydrogenase, subunit LldG	Kytococcus sedentarius DSM 20547 Gene: Ksed_04090: L-lactate dehydrogenase, subunit LldG	Leifsonia xyli subsp. xyli str. CTCB07	Renibacterium salmoninarum ATCC 33209	Tropheryma whipplei str. Twist	L-lactate dehydrogenase, subunit LldG

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog LldR - Micrococcineae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --