Regulog LldR - Frankineae/Propionibacterineae/Pseudonocardiaceae

Properties
Regulator type:	Transcription factor
Regulator family:	GntR/Others
Regulation mode:
Biological process:	Lactate utilization
Effector:	L-lactate
Phylum:	Actinobacteria
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 12 sites [see more]

Member of regulog collections

By taxonomy - Frankineae/Propionibacterineae/Pseudonocardiaceae
By TF family - GntR/Others
By effector - L-lactate
By pathway - Lactate utilization

Statistics of regulated genes
Genome	Genes	Operons
Nocardioides sp. JS614
Propionibacterium acnes KPA171202	5	2
Actinosynnema mirum DSM 43827	3	2
Saccharomonospora viridis DSM 43017
Saccharopolyspora erythraea NRRL 2338	4	2
Nakamurella multipartita DSM 44233	12	5
Frankia sp. EAN1pec
Frankia sp. CcI3
Acidothermus cellulolyticus 11B

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes										Function

CRON 1.
SACE_3508	Nocardioides sp. JS614	* Propionibacterium acnes KPA171202 Site: position = -272 score = 5.44288 sequence = TTTGGTCCGACCAAT Gene: PPA0165: Lactate-responsive regulator LldR in Actinobacteria, GntR family	* Actinosynnema mirum DSM 43827 Site: position = 1 score = 5.85682 sequence = TGTGGTCGGACCACA Gene: Amir_3039: Lactate-responsive regulator LldR in Actinobacteria, GntR family	Saccharomonospora viridis DSM 43017	* Saccharopolyspora erythraea NRRL 2338 Site: position = -67 score = 5.82024 sequence = TATGGTCAGACCACA Gene: SACE_3508: Lactate-responsive regulator LldR in Actinobacteria, GntR family	* Nakamurella multipartita DSM 44233 Site: position = -126 score = 5.9977 sequence = TTTGGTCTGACCAAA Gene: Namu_5224: GntR domain protein	Frankia sp. EAN1pec	Frankia sp. CcI3	Acidothermus cellulolyticus 11B	Lactate-responsive regulator LldR in Actinobacteria, GntR family

CRON 2.
lldD	Nocardioides sp. JS614 Gene: Noca_0280: L-lactate dehydrogenase (EC 1.1.2.3)	Propionibacterium acnes KPA171202	Actinosynnema mirum DSM 43827	Saccharomonospora viridis DSM 43017	2 Saccharopolyspora erythraea NRRL 2338 Gene: SACE_5887: L-lactate dehydrogenase (EC 1.1.2.3) Gene: SACE_4311: L-lactate dehydrogenase (EC 1.1.2.3)	* Nakamurella multipartita DSM 44233 Site: position = -78 score = 4.97701 sequence = TGTGGCCTGACCACC Site: position = -63 score = 5.82024 sequence = TATGGTCAGACCACA Gene: Namu_5297: L-lactate dehydrogenase (EC 1.1.2.3)	Frankia sp. EAN1pec	Frankia sp. CcI3	Acidothermus cellulolyticus 11B	L-lactate dehydrogenase (EC 1.1.2.3)

CRON 3.
Noca_0644	Nocardioides sp. JS614 Gene: Noca_0644: Putative transcriptional regulator, LysR family	Propionibacterium acnes KPA171202	Actinosynnema mirum DSM 43827	Saccharomonospora viridis DSM 43017	Saccharopolyspora erythraea NRRL 2338	2 Nakamurella multipartita DSM 44233* Site: position = -345 score = 5.49562 sequence = CTTGGTCAGACCACA Gene: Namu_3565: Putative transcriptional regulator, LysR family Site: position = -174 score = 5.30162 sequence = TTTGGTCTTACCATA Gene: Namu_1036: Putative transcriptional regulator, LysR family	Frankia sp. EAN1pec	Frankia sp. CcI3	Acidothermus cellulolyticus 11B	Putative transcriptional regulator, LysR family
lldP	Nocardioides sp. JS614	* Propionibacterium acnes KPA171202 Site: position = -77 score = 5.44288 sequence = ATTGGTCGGACCAAA Gene: PPA0166: L-lactate permease	Actinosynnema mirum DSM 43827	Saccharomonospora viridis DSM 43017	Saccharopolyspora erythraea NRRL 2338	4 Nakamurella multipartita DSM 44233* Gene: Namu_3729: L-lactate permease Gene: Namu_3564: L-lactate permease Gene: Namu_1035: L-lactate permease Site: position = -53 score = 5.9977 sequence = TTTGGTCAGACCAAA Gene: Namu_5225: L-lactate permease	Frankia sp. EAN1pec	Frankia sp. CcI3	Acidothermus cellulolyticus 11B	L-lactate permease
lldE	Nocardioides sp. JS614	Propionibacterium acnes KPA171202 Gene: PPA0167: L-lactate dehydrogenase, Fe-S oxidoreductase subunit LldE	* Actinosynnema mirum DSM 43827 Site: position = -24 score = 5.85682 sequence = TGTGGTCCGACCACA Gene: Amir_3038: L-lactate dehydrogenase, Fe-S oxidoreductase subunit LldE	Saccharomonospora viridis DSM 43017 Gene: Svir_37080: L-lactate dehydrogenase, Fe-S oxidoreductase subunit LldE	* Saccharopolyspora erythraea NRRL 2338 Site: position = -168 score = 5.82024 sequence = TGTGGTCTGACCATA Gene: SACE_3507: L-lactate dehydrogenase, Fe-S oxidoreductase subunit LldE	4 Nakamurella multipartita DSM 44233 Gene: Namu_3730: L-lactate dehydrogenase, Fe-S oxidoreductase subunit LldE Gene: Namu_3563: L-lactate dehydrogenase, Fe-S oxidoreductase subunit LldE Gene: Namu_5226: L-lactate dehydrogenase, Fe-S oxidoreductase subunit LldE Gene: Namu_1034: L-lactate dehydrogenase, Fe-S oxidoreductase subunit LldE	Frankia sp. EAN1pec	Frankia sp. CcI3	Acidothermus cellulolyticus 11B	L-lactate dehydrogenase, Fe-S oxidoreductase subunit LldE
lldF	Nocardioides sp. JS614	Propionibacterium acnes KPA171202 Gene: PPA0168: L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit LldF	Actinosynnema mirum DSM 43827 Gene: Amir_3037: L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit LldF	Saccharomonospora viridis DSM 43017 Gene: Svir_37070: L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit LldF	Saccharopolyspora erythraea NRRL 2338 Gene: SACE_3506: L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit LldF	4 Nakamurella multipartita DSM 44233 Gene: Namu_3731: L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit LldF Gene: Namu_1033: L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit LldF Gene: Namu_3562: L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit LldF Gene: Namu_5227: L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit LldF	Frankia sp. EAN1pec	Frankia sp. CcI3	Acidothermus cellulolyticus 11B	L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit LldF
lldG	Nocardioides sp. JS614	Propionibacterium acnes KPA171202 Gene: PPA0169: L-lactate dehydrogenase, subunit LldG	Actinosynnema mirum DSM 43827 Gene: Amir_3036: L-lactate dehydrogenase, subunit LldG	Saccharomonospora viridis DSM 43017 Gene: Svir_37060: L-lactate dehydrogenase, subunit LldG	Saccharopolyspora erythraea NRRL 2338 Gene: SACE_3505: L-lactate dehydrogenase, subunit LldG	4 Nakamurella multipartita DSM 44233 Gene: Namu_5228: L-lactate dehydrogenase, subunit LldG Gene: Namu_1032: L-lactate dehydrogenase, subunit LldG Gene: Namu_3561: L-lactate dehydrogenase, subunit LldG Gene: Namu_3732: L-lactate dehydrogenase, subunit LldG	Frankia sp. EAN1pec	Frankia sp. CcI3	Acidothermus cellulolyticus 11B	L-lactate dehydrogenase, subunit LldG

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog LldR - Frankineae/Propionibacterineae/Pseudonocardiaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --