Statistics of regulated genes

Genome	Genes	Operons
Lactococcus lactis subsp. cremoris SK11
Lactococcus lactis subsp. lactis Il1403
Streptococcus agalactiae 2603V/R
Streptococcus dysgalactiae subsp. equisimilis GGS_124	3	2
Streptococcus equi subsp. zooepidemicus MGCS10565
Streptococcus gallolyticus UCN34	3	2
Streptococcus gordonii str. Challis substr. CH1	3	2
Streptococcus mitis B6
Streptococcus mutans UA159	3	2
Streptococcus pneumoniae TIGR4	3	2
Streptococcus pyogenes M1 GAS	3	2
Streptococcus sanguinis SK36	3	2
Streptococcus suis 05ZYH33
Streptococcus thermophilus CNRZ1066
Streptococcus uberis 0140J	3	2

Clusters of co-Regulated Orthologous operoNs (CRONs)

Genes																Function
CRON 1.
treR	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	Streptococcus agalactiae 2603V/R	* Streptococcus dysgalactiae subsp. equisimilis GGS_124 Site: position = -102 score = 5.99604 sequence = CAAATTTGTCTACAAGTTGT Gene: SDEG_2070: Trehalose utilization transcriptional regulator TreR, GntR family	Streptococcus equi subsp. zooepidemicus MGCS10565	* Streptococcus gallolyticus UCN34 Site: position = -116 score = 5.62441 sequence = CCATTTTGTCTGCAAGTTGT Gene: GALLO_2176: Trehalose utilization transcriptional regulator TreR, GntR family	* Streptococcus gordonii str. Challis substr. CH1 Site: position = -93 score = 5.40973 sequence = CAAACGTGTATGCAAGATGT Gene: SGO_1654: Trehalose utilization transcriptional regulator TreR, GntR family	Streptococcus mitis B6	* Streptococcus mutans UA159 Site: position = -99 score = 5.62683 sequence = CAAATTTGTTGGCAAGTTGT Gene: SMU.2040: Trehalose utilization transcriptional regulator TreR, GntR family	* Streptococcus pneumoniae TIGR4 Site: position = -124 score = 5.80387 sequence = CAAACTTGTCTGCAACTTGT Gene: SP_1885: Trehalose utilization transcriptional regulator TreR, GntR family	* Streptococcus pyogenes M1 GAS Site: position = -102 score = 5.99604 sequence = CAAATTTGTCTACAAGTTGT Gene: SPy2099: Trehalose utilization transcriptional regulator TreR, GntR family	* Streptococcus sanguinis SK36 Site: position = -91 score = 5.51578 sequence = CAAAGATGTATGCAAGTTGT Gene: SSA_1753: Trehalose utilization transcriptional regulator TreR, GntR family	Streptococcus suis 05ZYH33 Gene: SSU05_0232: Trehalose utilization transcriptional regulator TreR, GntR family	Streptococcus thermophilus CNRZ1066	* Streptococcus uberis 0140J Site: position = -104 score = 5.91518 sequence = CAAATTTGTAGGCAAGTTGT Gene: SUB1764: Trehalose utilization transcriptional regulator TreR, GntR family	Trehalose utilization transcriptional regulator TreR, GntR family
CRON 2.
treP	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	Streptococcus agalactiae 2603V/R Gene: SAG0192: Trehalose-specific PTS system, EIIABC component (EC 2.7.1.69)	* Streptococcus dysgalactiae subsp. equisimilis GGS_124 Site: position = -128 score = 5.99604 sequence = ACAACTTGTAGACAAATTTG Gene: SDEG_2069: Trehalose-specific PTS system, EIIABC component (EC 2.7.1.69)	Streptococcus equi subsp. zooepidemicus MGCS10565	* Streptococcus gallolyticus UCN34 Site: position = -99 score = 5.62441 sequence = ACAACTTGCAGACAAAATGG Gene: GALLO_2175: Trehalose-specific PTS system, EIIABC component (EC 2.7.1.69)	* Streptococcus gordonii str. Challis substr. CH1 Site: position = -106 score = 5.40973 sequence = ACATCTTGCATACACGTTTG Gene: SGO_1653: Trehalose-specific PTS system, EIIABC component (EC 2.7.1.69)	Streptococcus mitis B6	* Streptococcus mutans UA159 Site: position = -94 score = 5.62683 sequence = ACAACTTGCCAACAAATTTG Gene: SMU.2038: Trehalose-specific PTS system, EIIABC component (EC 2.7.1.69)	* Streptococcus pneumoniae TIGR4 Site: position = -80 score = 5.80387 sequence = ACAAGTTGCAGACAAGTTTG Gene: SP_1884: Trehalose-specific PTS system, EIIABC component (EC 2.7.1.69)	* Streptococcus pyogenes M1 GAS Site: position = -128 score = 5.99604 sequence = ACAACTTGTAGACAAATTTG Gene: SPy2097: Trehalose-specific PTS system, EIIABC component (EC 2.7.1.69)	* Streptococcus sanguinis SK36 Site: position = -47 score = 5.51578 sequence = ACAACTTGCATACATCTTTG Gene: SSA_1752: Trehalose-specific PTS system, EIIABC component (EC 2.7.1.69)	Streptococcus suis 05ZYH33 Gene: SSU05_0231: Trehalose-specific PTS system, EIIABC component (EC 2.7.1.69)	Streptococcus thermophilus CNRZ1066	* Streptococcus uberis 0140J Site: position = -135 score = 5.91518 sequence = ACAACTTGCCTACAAATTTG Gene: SUB1763: Trehalose-specific PTS system, EIIABC component (EC 2.7.1.69)	Trehalose-specific PTS system, EIIABC component (EC 2.7.1.69)
treA	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	Streptococcus agalactiae 2603V/R Gene: SAG0193: Trehalose-6-phosphate hydrolase (EC 3.2.1.93)	Streptococcus dysgalactiae subsp. equisimilis GGS_124 Gene: SDEG_2068: Trehalose-6-phosphate hydrolase (EC 3.2.1.93)	Streptococcus equi subsp. zooepidemicus MGCS10565	Streptococcus gallolyticus UCN34 Gene: GALLO_2174: Trehalose-6-phosphate hydrolase (EC 3.2.1.93)	Streptococcus gordonii str. Challis substr. CH1 Gene: SGO_1652: Trehalose-6-phosphate hydrolase (EC 3.2.1.93)	Streptococcus mitis B6	Streptococcus mutans UA159 Gene: SMU.2037: Trehalose-6-phosphate hydrolase (EC 3.2.1.93)	Streptococcus pneumoniae TIGR4 Gene: SP_1883: Trehalose-6-phosphate hydrolase (EC 3.2.1.93)	Streptococcus pyogenes M1 GAS Gene: SPy2096: Trehalose-6-phosphate hydrolase (EC 3.2.1.93)	Streptococcus sanguinis SK36 Gene: SSA_1751: Trehalose-6-phosphate hydrolase (EC 3.2.1.93)	Streptococcus suis 05ZYH33 Gene: SSU05_0230: Trehalose-6-phosphate hydrolase (EC 3.2.1.93)	Streptococcus thermophilus CNRZ1066	Streptococcus uberis 0140J Gene: SUB1762: Trehalose-6-phosphate hydrolase (EC 3.2.1.93)	Trehalose-6-phosphate hydrolase (EC 3.2.1.93)

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