Regulog RspR - Enterobacteriales

Properties
Regulator type:	Transcription factor
Regulator family:	GntR/Others
Regulation mode:	repressor
Biological process:	L-gulonate utilization
Effector:	L-gulonate; D-mannonate
Phylum:	Proteobacteria/Gamma
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 9 sites [see more]

Member of regulog collections

By taxonomy - Enterobacteriales
By TF family - GntR/Others
By effector - L-gulonate
By effector - D-mannonate
By pathway - L-gulonate utilization

Statistics of regulated genes
Genome	Genes	Operons
Citrobacter koseri ATCC BAA-895	7	2
Edwardsiella tarda EIB202
Enterobacter sp. 638	4	1
Erwinia amylovora ATCC 49946
Erwinia carotovora subsp. atroseptica SCRI1043	5	1
Escherichia coli str. K-12 substr. MG1655	2	1
Klebsiella pneumoniae subsp. pneumoniae MGH 78578	3	2
Photorhabdus luminescens subsp. laumondii TTO1
Proteus mirabilis HI4320
Salmonella typhimurium LT2	2	1
Serratia proteamaculans 568	5	1
Yersinia pestis KIM

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes													Function

CRON 1.
rspA	* Citrobacter koseri ATCC BAA-895 Site: position = -70 score = 5.76572 sequence = TATACTTGTATGGTAGTAGT Gene: CKO_01575: D-mannonate dehydratase (EC 4.2.1.8), COG4948 family	Edwardsiella tarda EIB202	* Enterobacter sp. 638 Site: position = -70 score = 5.59139 sequence = AATACTTGTATGGTAGTAGC Gene: Ent638_1932: D-mannonate dehydratase (EC 4.2.1.8), COG4948 family	Erwinia amylovora ATCC 49946	* Erwinia carotovora subsp. atroseptica SCRI1043 Site: position = -37 score = 5.34206 sequence = TATACTTGTATGGTAGTCAG Gene: ECA0917: D-mannonate dehydratase (EC 4.2.1.8), COG4948 family	* Escherichia coli str. K-12 substr. MG1655 Site: position = -70 score = 5.82324 sequence = TATACTTGTATGGTAGTAGC Gene: b1581: D-mannonate dehydratase (EC 4.2.1.8), COG4948 family	Klebsiella pneumoniae subsp. pneumoniae MGH 78578	Photorhabdus luminescens subsp. laumondii TTO1	Proteus mirabilis HI4320	* Salmonella typhimurium LT2 Site: position = -69 score = 5.82324 sequence = TATACTTGTATGGTAGTAGC Gene: STM1505: D-mannonate dehydratase (EC 4.2.1.8), COG4948 family	* Serratia proteamaculans 568 Site: position = -74 score = 5.2965 sequence = CATACTTGTATGGTAGTTAG Gene: Spro_3563: D-mannonate dehydratase (EC 4.2.1.8), COG4948 family	Yersinia pestis KIM	D-mannonate dehydratase (EC 4.2.1.8), COG4948 family
rspB	Citrobacter koseri ATCC BAA-895 Gene: CKO_01574: L-gulonate dehydrogenase, COG1063 family	Edwardsiella tarda EIB202	Enterobacter sp. 638 Gene: Ent638_1933: L-gulonate dehydrogenase, COG1063 family	Erwinia amylovora ATCC 49946	Erwinia carotovora subsp. atroseptica SCRI1043 Gene: ECA0918: L-gulonate dehydrogenase, COG1063 family	Escherichia coli str. K-12 substr. MG1655 Gene: b1580: L-gulonate dehydrogenase, COG1063 family	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -49 score = 5.30871 sequence = CATACTTGTATGGTAATAAA Gene: KPN_03621: L-gulonate dehydrogenase, COG1063 family	Photorhabdus luminescens subsp. laumondii TTO1	Proteus mirabilis HI4320	Salmonella typhimurium LT2 Gene: STM1506: L-gulonate dehydrogenase, COG1063 family	Serratia proteamaculans 568 Gene: Spro_3564: L-gulonate dehydrogenase, COG1063 family	Yersinia pestis KIM	L-gulonate dehydrogenase, COG1063 family
rspC	Citrobacter koseri ATCC BAA-895 Gene: CKO_01573: Putative gulonate transporter, MFS superfamily, COG2271 family	Edwardsiella tarda EIB202	Enterobacter sp. 638 Gene: Ent638_1934: Putative gulonate transporter, MFS superfamily, COG2271 family	Erwinia amylovora ATCC 49946	Erwinia carotovora subsp. atroseptica SCRI1043 Gene: ECA0919: Putative gulonate transporter, MFS superfamily, COG2271 family	Escherichia coli str. K-12 substr. MG1655	Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Gene: KPN_03622: Putative gulonate transporter, MFS superfamily, COG2271 family	Photorhabdus luminescens subsp. laumondii TTO1	Proteus mirabilis HI4320	Salmonella typhimurium LT2	Serratia proteamaculans 568 Gene: Spro_3565: Putative gulonate transporter, MFS superfamily, COG2271 family	Yersinia pestis KIM	Putative gulonate transporter, MFS superfamily, COG2271 family
rspD	2 Citrobacter koseri ATCC BAA-895 Gene: CKO_03733: D-mannonate oxidoreductase (EC 1.1.1.57) Gene: CKO_01572: D-mannonate oxidoreductase (EC 1.1.1.57)	Edwardsiella tarda EIB202	Enterobacter sp. 638 Gene: Ent638_1935: D-mannonate oxidoreductase (EC 1.1.1.57)	Erwinia amylovora ATCC 49946	Erwinia carotovora subsp. atroseptica SCRI1043 Gene: ECA0920: D-mannonate oxidoreductase (EC 1.1.1.57)	Escherichia coli str. K-12 substr. MG1655 Gene: b1542: D-mannonate oxidoreductase (EC 1.1.1.57)	* Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Site: position = -132 score = 5.24367 sequence = TCTTCTTGTATGGTAGTTGA Gene: KPN_01587: D-mannonate oxidoreductase (EC 1.1.1.57)	Photorhabdus luminescens subsp. laumondii TTO1	Proteus mirabilis HI4320	Salmonella typhimurium LT2 Gene: STM1508: D-mannonate oxidoreductase (EC 1.1.1.57)	Serratia proteamaculans 568 Gene: Spro_3566: D-mannonate oxidoreductase (EC 1.1.1.57)	Yersinia pestis KIM	D-mannonate oxidoreductase (EC 1.1.1.57)
rspR	Citrobacter koseri ATCC BAA-895 Gene: CKO_01570: Transcriptional regulator for L-gulonate utilization, GntR family	Edwardsiella tarda EIB202	Enterobacter sp. 638 Gene: Ent638_1938: Transcriptional regulator for L-gulonate utilization, GntR family	Erwinia amylovora ATCC 49946	Erwinia carotovora subsp. atroseptica SCRI1043 Gene: ECA0921: Transcriptional regulator for L-gulonate utilization, GntR family	Escherichia coli str. K-12 substr. MG1655 Gene: b1540: Transcriptional regulator for L-gulonate utilization, GntR family	Klebsiella pneumoniae subsp. pneumoniae MGH 78578 Gene: KPN_01589: Transcriptional regulator for L-gulonate utilization, GntR family	Photorhabdus luminescens subsp. laumondii TTO1	Proteus mirabilis HI4320	Salmonella typhimurium LT2 Gene: STM1510: Transcriptional regulator for L-gulonate utilization, GntR family	Serratia proteamaculans 568 Gene: Spro_3567: Transcriptional regulator for L-gulonate utilization, GntR family	Yersinia pestis KIM	Transcriptional regulator for L-gulonate utilization, GntR family
uxaC2	* Citrobacter koseri ATCC BAA-895 Site: position = -133 score = 5.60565 sequence = TACACTTGTATGGTAGTAGA Gene: CKO_03735: Uronate isomerase (EC 5.3.1.12)	Edwardsiella tarda EIB202	Enterobacter sp. 638	Erwinia amylovora ATCC 49946	Erwinia carotovora subsp. atroseptica SCRI1043	Escherichia coli str. K-12 substr. MG1655	Klebsiella pneumoniae subsp. pneumoniae MGH 78578	Photorhabdus luminescens subsp. laumondii TTO1	Proteus mirabilis HI4320	Salmonella typhimurium LT2	Serratia proteamaculans 568	Yersinia pestis KIM	Uronate isomerase (EC 5.3.1.12)
COG2211	Citrobacter koseri ATCC BAA-895 Gene: CKO_03734: Oligogalacturonide transporter	Edwardsiella tarda EIB202	Enterobacter sp. 638	Erwinia amylovora ATCC 49946	Erwinia carotovora subsp. atroseptica SCRI1043	Escherichia coli str. K-12 substr. MG1655	Klebsiella pneumoniae subsp. pneumoniae MGH 78578	Photorhabdus luminescens subsp. laumondii TTO1	Proteus mirabilis HI4320	Salmonella typhimurium LT2	Serratia proteamaculans 568	Yersinia pestis KIM	Oligogalacturonide transporter

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

Export
	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog RspR - Enterobacteriales

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --