Regulog BioR - Rhodobacterales

Properties
Regulator type:	Transcription factor
Regulator family:	GntR/Others
Regulation mode:	repressor
Biological process:	Biotin biosynthesis
Effector:
Phylum:	Alphaproteobacteria
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 18 sites [see more]

Member of regulog collections

By taxonomy - Rhodobacterales
By TF family - GntR/Others
By pathway - Biotin biosynthesis

Statistics of regulated genes
Genome	Genes	Operons
Hyphomonas neptunium ATCC 15444
Jannaschia sp. CCS1
Loktanella vestfoldensis SKA53
Oceanicaulis alexandrii HTCC2633
Oceanicola batsensis HTCC2597
Oceanicola granulosus HTCC2516
Paracoccus denitrificans PD1222	10	4
Rhodobacter sphaeroides 2.4.1	3	2
Rhodobacterales bacterium HTCC2654
Roseobacter sp. MED193	4	1
Roseovarius nubinhibens ISM
Roseovarius sp. 217
Silicibacter TM1040	3	1
Silicibacter pomeroyi DSS-3	3	2
Sulfitobacter sp. EE-36	3	2

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes																Function

CRON 1.
bioM	Hyphomonas neptunium ATCC 15444	Jannaschia sp. CCS1	Loktanella vestfoldensis SKA53	Oceanicaulis alexandrii HTCC2633	Oceanicola batsensis HTCC2597	Oceanicola granulosus HTCC2516	Paracoccus denitrificans PD1222 Gene: Pden_5031: ATPase component BioM of energizing module of biotin ECF transporter	Rhodobacter sphaeroides 2.4.1 Gene: RSP_2175: ATPase component BioM of energizing module of biotin ECF transporter	Rhodobacterales bacterium HTCC2654 Gene: RB2654_23308: ATPase component BioM of energizing module of biotin ECF transporter	Roseobacter sp. MED193	Roseovarius nubinhibens ISM	Roseovarius sp. 217	* Silicibacter TM1040 Site: position = -94 score = 4.82597 sequence = TTATAGATAA Gene: TM1040_3661: ATPase component BioM of energizing module of biotin ECF transporter	Silicibacter pomeroyi DSS-3	Sulfitobacter sp. EE-36 Gene: EE36_08678: ATPase component BioM of energizing module of biotin ECF transporter	ATPase component BioM of energizing module of biotin ECF transporter
bioN	Hyphomonas neptunium ATCC 15444	Jannaschia sp. CCS1	Loktanella vestfoldensis SKA53	Oceanicaulis alexandrii HTCC2633	Oceanicola batsensis HTCC2597	Oceanicola granulosus HTCC2516	Paracoccus denitrificans PD1222 Gene: Pden_5032: Transmembrane component BioN of energizing module of biotin ECF transporter	Rhodobacter sphaeroides 2.4.1 Gene: RSP_2174: Transmembrane component BioN of energizing module of biotin ECF transporter	Rhodobacterales bacterium HTCC2654 Gene: RB2654_23303: Transmembrane component BioN of energizing module of biotin ECF transporter	Roseobacter sp. MED193	Roseovarius nubinhibens ISM	Roseovarius sp. 217	Silicibacter TM1040 Gene: TM1040_3660: Transmembrane component BioN of energizing module of biotin ECF transporter	Silicibacter pomeroyi DSS-3	Sulfitobacter sp. EE-36 Gene: EE36_08683: Transmembrane component BioN of energizing module of biotin ECF transporter	Transmembrane component BioN of energizing module of biotin ECF transporter
bioY	Hyphomonas neptunium ATCC 15444	Jannaschia sp. CCS1	Loktanella vestfoldensis SKA53	Oceanicaulis alexandrii HTCC2633	Oceanicola batsensis HTCC2597	Oceanicola granulosus HTCC2516	Paracoccus denitrificans PD1222 Gene: Pden_5033: Substrate-specific component BioY of biotin ECF transporter	Rhodobacter sphaeroides 2.4.1 Gene: RSP_2173: Substrate-specific component BioY of biotin ECF transporter	Rhodobacterales bacterium HTCC2654 Gene: RB2654_23298: Substrate-specific component BioY of biotin ECF transporter	Roseobacter sp. MED193	Roseovarius nubinhibens ISM	Roseovarius sp. 217	Silicibacter TM1040 Gene: TM1040_3659: Substrate-specific component BioY of biotin ECF transporter	Silicibacter pomeroyi DSS-3	Sulfitobacter sp. EE-36 Gene: EE36_05348: Substrate-specific component BioY of biotin ECF transporter	Substrate-specific component BioY of biotin ECF transporter

CRON 2.
bioB	Hyphomonas neptunium ATCC 15444 Gene: HNE_0048: Biotin synthase (EC 2.8.1.6)	Jannaschia sp. CCS1	Loktanella vestfoldensis SKA53	Oceanicaulis alexandrii HTCC2633 Gene: OA2633_11183: Biotin synthase (EC 2.8.1.6)	Oceanicola batsensis HTCC2597	Oceanicola granulosus HTCC2516	2 Paracoccus denitrificans PD1222* Gene: Pden_1433: Biotin synthase (EC 2.8.1.6) Site: position = -80 score = 4.22582 sequence = TAATAGATAA Site: position = -37 score = 4.07533 sequence = TTATAGATAC Gene: Pden_2916: Biotin synthase (EC 2.8.1.6)	Rhodobacter sphaeroides 2.4.1 Gene: RSP_1923: Biotin synthase (EC 2.8.1.6)	Rhodobacterales bacterium HTCC2654	* Roseobacter sp. MED193 Site: position = -164 score = 4.82597 sequence = TTATAGATAA Site: position = -132 score = 3.62979 sequence = TTATAGATGG Site: position = -67 score = 4.07533 sequence = ATATCTATAA Gene: MED193_07723: Biotin synthase (EC 2.8.1.6)	Roseovarius nubinhibens ISM	Roseovarius sp. 217	Silicibacter TM1040	Silicibacter pomeroyi DSS-3 Gene: SPO3338: Biotin synthase (EC 2.8.1.6)	Sulfitobacter sp. EE-36 Gene: EE36_13893: Biotin synthase (EC 2.8.1.6)	Biotin synthase (EC 2.8.1.6)
bioF	Hyphomonas neptunium ATCC 15444	Jannaschia sp. CCS1	Loktanella vestfoldensis SKA53	Oceanicaulis alexandrii HTCC2633	Oceanicola batsensis HTCC2597	Oceanicola granulosus HTCC2516	Paracoccus denitrificans PD1222 Gene: Pden_2917: 8-amino-7-oxononanoate synthase (EC 2.3.1.47)	Rhodobacter sphaeroides 2.4.1	Rhodobacterales bacterium HTCC2654	Roseobacter sp. MED193 Gene: MED193_07718: 8-amino-7-oxononanoate synthase (EC 2.3.1.47)	Roseovarius nubinhibens ISM	Roseovarius sp. 217	Silicibacter TM1040	Silicibacter pomeroyi DSS-3	Sulfitobacter sp. EE-36	8-amino-7-oxononanoate synthase (EC 2.3.1.47)
bioD	Hyphomonas neptunium ATCC 15444	Jannaschia sp. CCS1	Loktanella vestfoldensis SKA53	Oceanicaulis alexandrii HTCC2633	Oceanicola batsensis HTCC2597	Oceanicola granulosus HTCC2516	Paracoccus denitrificans PD1222 Gene: Pden_2918: Dethiobiotin synthetase (EC 6.3.3.3)	Rhodobacter sphaeroides 2.4.1	Rhodobacterales bacterium HTCC2654	Roseobacter sp. MED193 Gene: MED193_07713: Dethiobiotin synthetase (EC 6.3.3.3)	Roseovarius nubinhibens ISM	Roseovarius sp. 217	Silicibacter TM1040	Silicibacter pomeroyi DSS-3	Sulfitobacter sp. EE-36	Dethiobiotin synthetase (EC 6.3.3.3)
bioA	Hyphomonas neptunium ATCC 15444 Gene: HNE_1247: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)	Jannaschia sp. CCS1	Loktanella vestfoldensis SKA53	Oceanicaulis alexandrii HTCC2633	Oceanicola batsensis HTCC2597	Oceanicola granulosus HTCC2516	Paracoccus denitrificans PD1222 Gene: Pden_2919: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)	Rhodobacter sphaeroides 2.4.1	Rhodobacterales bacterium HTCC2654	Roseobacter sp. MED193 Gene: MED193_07708: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)	Roseovarius nubinhibens ISM	Roseovarius sp. 217	Silicibacter TM1040	Silicibacter pomeroyi DSS-3	Sulfitobacter sp. EE-36	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)
bioG	Hyphomonas neptunium ATCC 15444	Jannaschia sp. CCS1	Loktanella vestfoldensis SKA53	Oceanicaulis alexandrii HTCC2633	Oceanicola batsensis HTCC2597	Oceanicola granulosus HTCC2516	Paracoccus denitrificans PD1222 Gene: Pden_2920: Biotin synthesis protein bioG	Rhodobacter sphaeroides 2.4.1	Rhodobacterales bacterium HTCC2654	Roseobacter sp. MED193	Roseovarius nubinhibens ISM	Roseovarius sp. 217	Silicibacter TM1040	Silicibacter pomeroyi DSS-3	Sulfitobacter sp. EE-36	Biotin synthesis protein bioG
bioC	Hyphomonas neptunium ATCC 15444	Jannaschia sp. CCS1	Loktanella vestfoldensis SKA53	Oceanicaulis alexandrii HTCC2633	Oceanicola batsensis HTCC2597	Oceanicola granulosus HTCC2516	Paracoccus denitrificans PD1222 Gene: Pden_2921: Biotin synthesis protein bioC	Rhodobacter sphaeroides 2.4.1	Rhodobacterales bacterium HTCC2654	Roseobacter sp. MED193	Roseovarius nubinhibens ISM	Roseovarius sp. 217	Silicibacter TM1040	Silicibacter pomeroyi DSS-3	Sulfitobacter sp. EE-36	Biotin synthesis protein bioC
bioY	Hyphomonas neptunium ATCC 15444	Jannaschia sp. CCS1	Loktanella vestfoldensis SKA53	Oceanicaulis alexandrii HTCC2633	Oceanicola batsensis HTCC2597	Oceanicola granulosus HTCC2516	* Paracoccus denitrificans PD1222 Site: position = -84 score = 4.82597 sequence = TTATCTATAA Site: position = -40 score = 4.39409 sequence = TTATAGATAG Gene: Pden_1432: Core component BioY of biotin ECF transporter	* Rhodobacter sphaeroides 2.4.1 Site: position = -203 score = 4.82597 sequence = TTATCTATAA Site: position = -159 score = 4.39409 sequence = TTATAGATAG Gene: RSP_1924: Core component BioY of biotin ECF transporter	Rhodobacterales bacterium HTCC2654	Roseobacter sp. MED193	Roseovarius nubinhibens ISM	Roseovarius sp. 217	Silicibacter TM1040	* Silicibacter pomeroyi DSS-3 Site: position = -64 score = 4.39409 sequence = TTATAGATAG Site: position = -23 score = 4.82597 sequence = TTATCTATAA Gene: SPO3339: Core component BioY of biotin ECF transporter	* Sulfitobacter sp. EE-36 Site: position = -83 score = 4.82597 sequence = TTATCTATAA Gene: EE36_13898: Core component BioY of biotin ECF transporter	Core component BioY of biotin ECF transporter

CRON 3.
bioR	Hyphomonas neptunium ATCC 15444	Jannaschia sp. CCS1	Loktanella vestfoldensis SKA53	Oceanicaulis alexandrii HTCC2633	Oceanicola batsensis HTCC2597	Oceanicola granulosus HTCC2516	2 Paracoccus denitrificans PD1222* Site: position = -39 score = 4.32371 sequence = TTATCGACAA Gene: Pden_2922: Biotin metabolism regulatory protein BioR, GntR family Site: position = -13 score = 4.82597 sequence = TTATCTATAA Gene: Pden_1431: Biotin metabolism regulatory protein BioR, GntR family	* Rhodobacter sphaeroides 2.4.1 Site: position = -13 score = 4.82597 sequence = TTATCTATAA Gene: RSP_1925: Biotin metabolism regulatory protein BioR, GntR family	Rhodobacterales bacterium HTCC2654	Roseobacter sp. MED193 Gene: MED193_13378: Biotin metabolism regulatory protein BioR, GntR family	Roseovarius nubinhibens ISM	Roseovarius sp. 217	Silicibacter TM1040 Gene: TM1040_3010: Biotin metabolism regulatory protein BioR, GntR family	* Silicibacter pomeroyi DSS-3 Site: position = -13 score = 4.82597 sequence = TTATCTATAA Gene: SPO3340: Biotin metabolism regulatory protein BioR, GntR family	* Sulfitobacter sp. EE-36 Site: position = -61 score = 4.39409 sequence = CTATCTATAA Gene: EE36_13903: Biotin metabolism regulatory protein BioR, GntR family	Biotin metabolism regulatory protein BioR, GntR family

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog BioR - Rhodobacterales

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --