Regulog AgaR2 - Streptococcaceae

Properties
Regulator type:	Transcription factor
Regulator family:	GntR/Others
Regulation mode:	repressor
Biological process:	N-acetylgalactosamine utilization
Effector:	N-acetylgalactosamine
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 8 sites [see more]

Member of regulog collections

By taxonomy - Streptococcaceae
By TF family - GntR/Others
By effector - N-acetylgalactosamine
By pathway - N-acetylgalactosamine utilization

Statistics of regulated genes
Genome	Genes	Operons
Lactococcus lactis subsp. cremoris SK11
Lactococcus lactis subsp. lactis Il1403
Streptococcus agalactiae 2603V/R
Streptococcus dysgalactiae subsp. equisimilis GGS_124	3	1
Streptococcus equi subsp. zooepidemicus MGCS10565	3	1
Streptococcus gallolyticus UCN34
Streptococcus gordonii str. Challis substr. CH1
Streptococcus mitis B6
Streptococcus mutans UA159
Streptococcus pneumoniae TIGR4
Streptococcus pyogenes M1 GAS	2	1
Streptococcus sanguinis SK36
Streptococcus suis 05ZYH33	9	4
Streptococcus thermophilus CNRZ1066
Streptococcus uberis 0140J	3	1

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes																Function

CRON 1.
bgaC	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	Streptococcus agalactiae 2603V/R	Streptococcus dysgalactiae subsp. equisimilis GGS_124 Gene: SDEG_0679: Beta-galactosidase (EC 3.2.1.23)	Streptococcus equi subsp. zooepidemicus MGCS10565 Gene: Sez_0741: Beta-galactosidase (EC 3.2.1.23)	Streptococcus gallolyticus UCN34	Streptococcus gordonii str. Challis substr. CH1 Gene: SGO_0043: Beta-galactosidase (EC 3.2.1.23)	Streptococcus mitis B6 Gene: smi_0079: Beta-galactosidase (EC 3.2.1.23)	Streptococcus mutans UA159	Streptococcus pneumoniae TIGR4 Gene: SP_0060: Beta-galactosidase (EC 3.2.1.23)	Streptococcus pyogenes M1 GAS	Streptococcus sanguinis SK36 Gene: SSA_0053: Beta-galactosidase (EC 3.2.1.23)	* Streptococcus suis 05ZYH33 Site: position = -69 score = 5.19906 sequence = TACTGGACATAACCACAA Gene: SSU05_0449: Beta-galactosidase (EC 3.2.1.23)	Streptococcus thermophilus CNRZ1066	Streptococcus uberis 0140J Gene: SUB0042: Beta-galactosidase (EC 3.2.1.23)	Beta-galactosidase (EC 3.2.1.23)
gadV	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	Streptococcus agalactiae 2603V/R	Streptococcus dysgalactiae subsp. equisimilis GGS_124 Gene: SDEG_0680: Predicted galactosamine disaccharide-specific PTS, EIIB component (EC 2.7.1.69)	Streptococcus equi subsp. zooepidemicus MGCS10565 Gene: Sez_0742: Predicted galactosamine disaccharide-specific PTS, EIIB component (EC 2.7.1.69)	Streptococcus gallolyticus UCN34	Streptococcus gordonii str. Challis substr. CH1 Gene: SGO_0044: Predicted galactosamine disaccharide-specific PTS, EIIB component (EC 2.7.1.69)	Streptococcus mitis B6 Gene: smi_0080: Predicted galactosamine disaccharide-specific PTS, EIIB component (EC 2.7.1.69)	Streptococcus mutans UA159	Streptococcus pneumoniae TIGR4 Gene: SP_0061: Predicted galactosamine disaccharide-specific PTS, EIIB component (EC 2.7.1.69)	Streptococcus pyogenes M1 GAS	Streptococcus sanguinis SK36 Gene: SSA_0054: Predicted galactosamine disaccharide-specific PTS, EIIB component (EC 2.7.1.69)	Streptococcus suis 05ZYH33 Gene: SSU05_0450: Predicted galactosamine disaccharide-specific PTS, EIIB component (EC 2.7.1.69)	Streptococcus thermophilus CNRZ1066	Streptococcus uberis 0140J Gene: SUB0043: Predicted galactosamine disaccharide-specific PTS, EIIB component (EC 2.7.1.69)	Predicted galactosamine disaccharide-specific PTS, EIIB component (EC 2.7.1.69)
gadW	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	Streptococcus agalactiae 2603V/R	Streptococcus dysgalactiae subsp. equisimilis GGS_124 Gene: SDEG_0681: Predicted galactosamine disaccharide-specific PTS, EIIC component (EC 2.7.1.69)	Streptococcus equi subsp. zooepidemicus MGCS10565 Gene: Sez_0743: Predicted galactosamine disaccharide-specific PTS, EIIC component (EC 2.7.1.69)	Streptococcus gallolyticus UCN34	Streptococcus gordonii str. Challis substr. CH1 Gene: SGO_0045: Predicted galactosamine disaccharide-specific PTS, EIIC component (EC 2.7.1.69)	Streptococcus mitis B6 Gene: smi_0081: Predicted galactosamine disaccharide-specific PTS, EIIC component (EC 2.7.1.69)	Streptococcus mutans UA159	Streptococcus pneumoniae TIGR4 Gene: SP_0062: Predicted galactosamine disaccharide-specific PTS, EIIC component (EC 2.7.1.69)	Streptococcus pyogenes M1 GAS	Streptococcus sanguinis SK36 Gene: SSA_0055: Predicted galactosamine disaccharide-specific PTS, EIIC component (EC 2.7.1.69)	Streptococcus suis 05ZYH33 Gene: SSU05_0451: Predicted galactosamine disaccharide-specific PTS, EIIC component (EC 2.7.1.69)	Streptococcus thermophilus CNRZ1066	Streptococcus uberis 0140J Gene: SUB0044: Predicted galactosamine disaccharide-specific PTS, EIIC component (EC 2.7.1.69)	Predicted galactosamine disaccharide-specific PTS, EIIC component (EC 2.7.1.69)
gadE	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	Streptococcus agalactiae 2603V/R	Streptococcus dysgalactiae subsp. equisimilis GGS_124 Gene: SDEG_0682: Predicted galactosamine disaccharide-specific PTS, EIID component (EC 2.7.1.69)	Streptococcus equi subsp. zooepidemicus MGCS10565 Gene: Sez_0744: Predicted galactosamine disaccharide-specific PTS, EIID component (EC 2.7.1.69)	Streptococcus gallolyticus UCN34	Streptococcus gordonii str. Challis substr. CH1 Gene: SGO_0046: Predicted galactosamine disaccharide-specific PTS, EIID component (EC 2.7.1.69)	Streptococcus mitis B6 Gene: smi_0082: Predicted galactosamine disaccharide-specific PTS, EIID component (EC 2.7.1.69)	Streptococcus mutans UA159	Streptococcus pneumoniae TIGR4 Gene: SP_0063: Predicted galactosamine disaccharide-specific PTS, EIID component (EC 2.7.1.69)	Streptococcus pyogenes M1 GAS	Streptococcus sanguinis SK36 Gene: SSA_0056: Predicted galactosamine disaccharide-specific PTS, EIID component (EC 2.7.1.69)	Streptococcus suis 05ZYH33 Gene: SSU05_0452: Predicted galactosamine disaccharide-specific PTS, EIID component (EC 2.7.1.69)	Streptococcus thermophilus CNRZ1066	Streptococcus uberis 0140J Gene: SUB0045: Predicted galactosamine disaccharide-specific PTS, EIID component (EC 2.7.1.69)	Predicted galactosamine disaccharide-specific PTS, EIID component (EC 2.7.1.69)
gadF	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	Streptococcus agalactiae 2603V/R	Streptococcus dysgalactiae subsp. equisimilis GGS_124 Gene: SDEG_0683: Predicted galactosamine disaccharide-specific PTS, EIIA component (EC 2.7.1.69)	Streptococcus equi subsp. zooepidemicus MGCS10565 Gene: Sez_0745: Predicted galactosamine disaccharide-specific PTS, EIIA component (EC 2.7.1.69)	Streptococcus gallolyticus UCN34	Streptococcus gordonii str. Challis substr. CH1 Gene: SGO_0047: Predicted galactosamine disaccharide-specific PTS, EIIA component (EC 2.7.1.69)	Streptococcus mitis B6 Gene: smi_0083: Predicted galactosamine disaccharide-specific PTS, EIIA component (EC 2.7.1.69)	Streptococcus mutans UA159	Streptococcus pneumoniae TIGR4 Gene: SP_0064: Predicted galactosamine disaccharide-specific PTS, EIIA component (EC 2.7.1.69)	Streptococcus pyogenes M1 GAS	Streptococcus sanguinis SK36 Gene: SSA_0057: Predicted galactosamine disaccharide-specific PTS, EIIA component (EC 2.7.1.69)	Streptococcus suis 05ZYH33 Gene: SSU05_0453: Predicted galactosamine disaccharide-specific PTS, EIIA component (EC 2.7.1.69)	Streptococcus thermophilus CNRZ1066	Streptococcus uberis 0140J Gene: SUB0046: Predicted galactosamine disaccharide-specific PTS, EIIA component (EC 2.7.1.69)	Predicted galactosamine disaccharide-specific PTS, EIIA component (EC 2.7.1.69)

CRON 2.
agaR	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	Streptococcus agalactiae 2603V/R	Streptococcus dysgalactiae subsp. equisimilis GGS_124 Gene: SDEG_0678: N-acetylgalactosamine utilization transcriptional regulator AgaR, GntR family	Streptococcus equi subsp. zooepidemicus MGCS10565 Gene: Sez_0740: N-acetylgalactosamine utilization transcriptional regulator AgaR, GntR family	Streptococcus gallolyticus UCN34	Streptococcus gordonii str. Challis substr. CH1 Gene: SGO_0042: N-acetylgalactosamine utilization transcriptional regulator AgaR, GntR family	Streptococcus mitis B6 Gene: smi_0078: N-acetylgalactosamine utilization transcriptional regulator AgaR, GntR family	Streptococcus mutans UA159	Streptococcus pneumoniae TIGR4 Gene: SP_0058: N-acetylgalactosamine utilization transcriptional regulator AgaR, GntR family	Streptococcus pyogenes M1 GAS	Streptococcus sanguinis SK36 Gene: SSA_0052: N-acetylgalactosamine utilization transcriptional regulator AgaR, GntR family	* Streptococcus suis 05ZYH33 Site: position = -134 score = 5.19906 sequence = TTGTGGTTATGTCCAGTA Gene: SSU05_0448: N-acetylgalactosamine utilization transcriptional regulator AgaR, GntR family	Streptococcus thermophilus CNRZ1066	Streptococcus uberis 0140J Gene: SUB0041: N-acetylgalactosamine utilization transcriptional regulator AgaR, GntR family	N-acetylgalactosamine utilization transcriptional regulator AgaR, GntR family

CRON 3.
agaR2	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	Streptococcus agalactiae 2603V/R	* Streptococcus dysgalactiae subsp. equisimilis GGS_124 Site: position = -22 score = 5.6548 sequence = AGGTGGTTATAACAAGTT Gene: SDEG_0675: N-acetylgalactosamine utilization transcriptional regulator AgaR2, GntR family	* Streptococcus equi subsp. zooepidemicus MGCS10565 Site: position = -30 score = 6.01273 sequence = AAGTGGTTATAACAAGTT Gene: Sez_0737: N-acetylgalactosamine utilization transcriptional regulator AgaR2, GntR family	Streptococcus gallolyticus UCN34	Streptococcus gordonii str. Challis substr. CH1	Streptococcus mitis B6	Streptococcus mutans UA159	Streptococcus pneumoniae TIGR4	* Streptococcus pyogenes M1 GAS Site: position = -31 score = 6.01273 sequence = AAGTGGTTATAACAAGTT Gene: SPy0715: N-acetylgalactosamine utilization transcriptional regulator AgaR2, GntR family	Streptococcus sanguinis SK36	Streptococcus suis 05ZYH33 Gene: SSU05_0447: N-acetylgalactosamine utilization transcriptional regulator AgaR2, GntR family	Streptococcus thermophilus CNRZ1066	* Streptococcus uberis 0140J Site: position = -30 score = 5.84142 sequence = AAGTGTTTATAACCAGTT Gene: SUB0038: N-acetylgalactosamine utilization transcriptional regulator AgaR2, GntR family	N-acetylgalactosamine utilization transcriptional regulator AgaR2, GntR family
agaS	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	Streptococcus agalactiae 2603V/R	Streptococcus dysgalactiae subsp. equisimilis GGS_124 Gene: SDEG_0676: Predicted galactosamine-6-phosphate isomerase (EC 5.3.1.-)	Streptococcus equi subsp. zooepidemicus MGCS10565 Gene: Sez_0738: Predicted galactosamine-6-phosphate isomerase (EC 5.3.1.-)	Streptococcus gallolyticus UCN34	Streptococcus gordonii str. Challis substr. CH1 Gene: SGO_0048: Predicted galactosamine-6-phosphate isomerase (EC 5.3.1.-)	Streptococcus mitis B6 Gene: smi_0084: Predicted galactosamine-6-phosphate isomerase (EC 5.3.1.-)	Streptococcus mutans UA159	Streptococcus pneumoniae TIGR4 Gene: SP_0065: Predicted galactosamine-6-phosphate isomerase (EC 5.3.1.-)	Streptococcus pyogenes M1 GAS Gene: SPy0716: Predicted galactosamine-6-phosphate isomerase (EC 5.3.1.-)	Streptococcus sanguinis SK36 Gene: SSA_0060: Predicted galactosamine-6-phosphate isomerase (EC 5.3.1.-)	* Streptococcus suis 05ZYH33 Site: position = -68 score = 6.02188 sequence = AACTGGTTATAACCAGAA Gene: SSU05_0195: Predicted galactosamine-6-phosphate isomerase (EC 5.3.1.-)	Streptococcus thermophilus CNRZ1066	Streptococcus uberis 0140J Gene: SUB0039: Predicted galactosamine-6-phosphate isomerase (EC 5.3.1.-)	Predicted galactosamine-6-phosphate isomerase (EC 5.3.1.-)
agaY	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	Streptococcus agalactiae 2603V/R	Streptococcus dysgalactiae subsp. equisimilis GGS_124 Gene: SDEG_0677: Tagatose 1,6-diphosphate aldolase (EC 4.1.2.40)	Streptococcus equi subsp. zooepidemicus MGCS10565 Gene: Sez_0739: Tagatose 1,6-diphosphate aldolase (EC 4.1.2.40)	Streptococcus gallolyticus UCN34	Streptococcus gordonii str. Challis substr. CH1	Streptococcus mitis B6	Streptococcus mutans UA159 Gene: SMU.116: Tagatose 1,6-diphosphate aldolase (EC 4.1.2.40)	Streptococcus pneumoniae TIGR4	Streptococcus pyogenes M1 GAS Gene: SPy1704: Tagatose 1,6-diphosphate aldolase (EC 4.1.2.40)	Streptococcus sanguinis SK36 Gene: SSA_0061: Tagatose 1,6-diphosphate aldolase (EC 4.1.2.40)	Streptococcus suis 05ZYH33 Gene: SSU05_1258: Tagatose 1,6-diphosphate aldolase (EC 4.1.2.40)	Streptococcus thermophilus CNRZ1066	Streptococcus uberis 0140J Gene: SUB0040: Tagatose 1,6-diphosphate aldolase (EC 4.1.2.40)	Tagatose 1,6-diphosphate aldolase (EC 4.1.2.40)
agaA	Lactococcus lactis subsp. cremoris SK11	Lactococcus lactis subsp. lactis Il1403	Streptococcus agalactiae 2603V/R	Streptococcus dysgalactiae subsp. equisimilis GGS_124	Streptococcus equi subsp. zooepidemicus MGCS10565	Streptococcus gallolyticus UCN34	Streptococcus gordonii str. Challis substr. CH1	Streptococcus mitis B6	Streptococcus mutans UA159	Streptococcus pneumoniae TIGR4	Streptococcus pyogenes M1 GAS	Streptococcus sanguinis SK36	* Streptococcus suis 05ZYH33 Site: position = -2 score = 5.82972 sequence = ATATGGTTATAACCAGTT Gene: SSU05_1259: N-acetylgalactosamine-6-phosphate deacetylase (EC 3.5.1.25)	Streptococcus thermophilus CNRZ1066	Streptococcus uberis 0140J	N-acetylgalactosamine-6-phosphate deacetylase (EC 3.5.1.25)

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog AgaR2 - Streptococcaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --