Regulog LldR - Mycobacteriaceae

Properties
Regulator type:	Transcription factor
Regulator family:	GntR/Others
Regulation mode:
Biological process:	Lactate utilization
Effector:	L-lactate
Phylum:	Actinobacteria
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 8 sites [see more]

Member of regulog collections

By taxonomy - Mycobacteriaceae
By TF family - GntR/Others
By effector - L-lactate
By pathway - Lactate utilization

Statistics of regulated genes
Genome	Genes	Operons
Mycobacterium abscessus ATCC 19977
Mycobacterium avium 104
Mycobacterium flavescens PYR-GCK
Mycobacterium leprae TN
Mycobacterium marinum M
Mycobacterium smegmatis str. MC2 155	4	2
Mycobacterium sp. JLS	4	2
Mycobacterium tuberculosis H37Rv
Mycobacterium vanbaalenii PYR-1

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes										Function

CRON 1.
lldR	Mycobacterium abscessus ATCC 19977	Mycobacterium avium 104	Mycobacterium flavescens PYR-GCK	Mycobacterium leprae TN	Mycobacterium marinum M	* Mycobacterium smegmatis str. MC2 155 Site: position = -42 score = 6.19742 sequence = TGTGGTCAGACCACA Site: position = -76 score = 6.19742 sequence = TGTGGTCTGACCACA Gene: MSMEG_0596: Lactate-responsive regulator LldR in Actinobacteria, GntR family	* Mycobacterium sp. JLS Site: position = -23 score = 6.19742 sequence = TGTGGTCTGACCACA Site: position = 1 score = 6.005 sequence = TGTGGTCGGACCACA Gene: Mjls_4765: Lactate-responsive regulator LldR in Actinobacteria, GntR family	Mycobacterium tuberculosis H37Rv	Mycobacterium vanbaalenii PYR-1	Lactate-responsive regulator LldR in Actinobacteria, GntR family

CRON 2.
lldE	Mycobacterium abscessus ATCC 19977	Mycobacterium avium 104	Mycobacterium flavescens PYR-GCK Gene: Mflv_3704: L-lactate dehydrogenase, Fe-S oxidoreductase subunit LldE	Mycobacterium leprae TN	Mycobacterium marinum M	* Mycobacterium smegmatis str. MC2 155 Site: position = -62 score = 6.19742 sequence = TGTGGTCTGACCACA Site: position = -28 score = 6.19742 sequence = TGTGGTCAGACCACA Gene: MSMEG_0595: L-lactate dehydrogenase, Fe-S oxidoreductase subunit LldE	* Mycobacterium sp. JLS Site: position = -36 score = 6.19742 sequence = TGTGGTCAGACCACA Site: position = -60 score = 6.005 sequence = TGTGGTCCGACCACA Gene: Mjls_4766: L-lactate dehydrogenase, Fe-S oxidoreductase subunit LldE	Mycobacterium tuberculosis H37Rv	Mycobacterium vanbaalenii PYR-1 Gene: Mvan_2709: L-lactate dehydrogenase, Fe-S oxidoreductase subunit LldE	L-lactate dehydrogenase, Fe-S oxidoreductase subunit LldE
lldF	Mycobacterium abscessus ATCC 19977	Mycobacterium avium 104	Mycobacterium flavescens PYR-GCK Gene: Mflv_3703: L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit LldF	Mycobacterium leprae TN	Mycobacterium marinum M	Mycobacterium smegmatis str. MC2 155 Gene: MSMEG_0594: L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit LldF	Mycobacterium sp. JLS Gene: Mjls_4767: L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit LldF	Mycobacterium tuberculosis H37Rv	Mycobacterium vanbaalenii PYR-1 Gene: Mvan_2710: L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit LldF	L-lactate dehydrogenase, Iron-sulfur cluster-binding subunit LldF
lldG	Mycobacterium abscessus ATCC 19977	Mycobacterium avium 104	Mycobacterium flavescens PYR-GCK Gene: Mflv_3702: L-lactate dehydrogenase, subunit LldG	Mycobacterium leprae TN	Mycobacterium marinum M	Mycobacterium smegmatis str. MC2 155 Gene: MSMEG_0593: L-lactate dehydrogenase, subunit LldG	Mycobacterium sp. JLS Gene: Mjls_4768: L-lactate dehydrogenase, subunit LldG	Mycobacterium tuberculosis H37Rv	Mycobacterium vanbaalenii PYR-1 Gene: Mvan_2711: L-lactate dehydrogenase, subunit LldG	L-lactate dehydrogenase, subunit LldG

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog LldR - Mycobacteriaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --