Regulog FadR - Vibrionales

Properties
Regulator type:	Transcription factor
Regulator family:	GntR/Others
Regulation mode:	repressor (activator)
Biological process:	Fatty acid degradation
Effector:	Palmitoyl-CoA; Oleoyl-CoA
Phylum:	Proteobacteria/gamma
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 77 sites [see more]

Member of regulog collections

By trascription factor - FadR
By taxonomy - Vibrionales
By TF family - GntR/Others
By effector - Palmitoyl-CoA
By effector - Oleoyl-CoA
By pathway - Fatty acid degradation

Statistics of regulated genes
Genome	Genes	Operons
Vibrio cholerae O1 biovar eltor str. N16961	8	7
Vibrio vulnificus CMCP6	9	7
Vibrio harveyi ATCC BAA-1116	10	8
Vibrio parahaemolyticus RIMD 2210633	9	7
Vibrio shilonii AK1	9	7
Vibrio splendidus LGP32	9	7
Vibrio fischeri ES114	9	7
Vibrio salmonicida LFI1238	9	8
Vibrio angustum S14	8	6
Photobacterium profundum SS9	8	6

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes											Function

CRON 1.
fadL	* Vibrio cholerae O1 biovar eltor str. N16961 Site: position = -125 score = 3.4389 sequence = CAATGGTCGGATTTCTA Gene: VC1043: Long-chain fatty acid transport protein	* Vibrio vulnificus CMCP6 Site: position = -108 score = 3.30655 sequence = CAATGGTCGGATTTGTA Gene: VV1_1972: Long-chain fatty acid transport protein	* Vibrio harveyi ATCC BAA-1116 Site: position = -103 score = 3.30655 sequence = CAATGGTCGGATTTGTA Gene: VIBHAR_03124: Long-chain fatty acid transport protein	Vibrio parahaemolyticus RIMD 2210633 Gene: VP2212: Long-chain fatty acid transport protein	* Vibrio shilonii AK1 Site: position = -115 score = 4.76194 sequence = TACTGGTCAGATTTCTA Gene: VSAK1_03229: Long-chain fatty acid transport protein	* Vibrio splendidus LGP32 Site: position = -107 score = 3.30655 sequence = CAATGGTCGGATTTGTA Gene: VS_0861: Long-chain fatty acid transport protein	* Vibrio fischeri ES114 Site: position = -128 score = 3.16746 sequence = CAGTGGTCGGATTTGTC Gene: VF_1812: Long-chain fatty acid transport protein	* Vibrio salmonicida LFI1238 Site: position = -128 score = 3.31403 sequence = TAGTGGTCGGATTTGTC Gene: VSAL_I2269: Long-chain fatty acid transport protein	2 Vibrio angustum S14* Gene: VAS14_05623: Long-chain fatty acid transport protein Site: position = -107 score = 4.56992 sequence = CACTGGTCAGATTTGAT Gene: VAS14_17316: Long-chain fatty acid transport protein	* Photobacterium profundum SS9 Site: position = -101 score = 4.95795 sequence = AACTGGTCAGATTTGAT Gene: PBPRA0958: Long-chain fatty acid transport protein	Long-chain fatty acid transport protein

CRON 2.
fabA	* Vibrio cholerae O1 biovar eltor str. N16961 Site: position = -70 score = 3.25674 sequence = CACTGATCGGAGTTGTT Gene: VC1483: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.60)	* Vibrio vulnificus CMCP6 Site: position = -86 score = 4.20745 sequence = AACTGGTTTGTCTAGTA Site: position = -71 score = 3.40332 sequence = TACTGATCGGAGTTGTT Gene: VV1_2629: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.60)	* Vibrio harveyi ATCC BAA-1116 Site: position = -85 score = 4.20745 sequence = AACTGGTTTGTCTAGTA Site: position = -70 score = 3.40332 sequence = TACTGATCGGAGTTGTT Gene: VIBHAR_02332: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.60)	* Vibrio parahaemolyticus RIMD 2210633 Site: position = -85 score = 4.20745 sequence = AACTGGTTTGTCTAGTA Site: position = -70 score = 3.40332 sequence = TACTGATCGGAGTTGTT Gene: VP1591: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.60)	Vibrio shilonii AK1 Gene: VSAK1_05230: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.60)	* Vibrio splendidus LGP32 Site: position = -79 score = 4.20745 sequence = AACTGGTTTGTCTAGTA Site: position = -64 score = 4.00285 sequence = TACTGATCGGACTTGTT Gene: VS_1429: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.60)	Vibrio fischeri ES114 Gene: VF_1292: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.60)	* Vibrio salmonicida LFI1238 Site: position = -71 score = 4.23772 sequence = AGCTGATCAGACTTGAT Site: position = -86 score = 4.58246 sequence = AACTGGTTTAACCAGAG Gene: VSAL_I1556: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.60)	* Vibrio angustum S14 Site: position = -74 score = 3.64476 sequence = AACTGATCCGAGTTGTT Site: position = -89 score = 4.57125 sequence = AACTGGTTTGTCCAGAA Gene: VAS14_02868: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.60)	* Photobacterium profundum SS9 Site: position = -74 score = 3.25674 sequence = CACTGATCCGAGTTGTT Gene: PBPRA1773: 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.60)	3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.60)

CRON 3.
fadB	* Vibrio cholerae O1 biovar eltor str. N16961 Site: position = -76 score = 5.44213 sequence = AACTGGTCAAACCAGAA Gene: VC2758: Enoyl-CoA hydratase (EC 4.2.1.17)	* Vibrio vulnificus CMCP6 Site: position = -109 score = 5.11679 sequence = AACTGGTCTAACCAGAA Gene: VV1_0981: Enoyl-CoA hydratase (EC 4.2.1.17)	* Vibrio harveyi ATCC BAA-1116 Site: position = -126 score = 5.05411 sequence = CACTGGTCAAACCAGAA Gene: VIBHAR_00460: Enoyl-CoA hydratase (EC 4.2.1.17)	* Vibrio parahaemolyticus RIMD 2210633 Site: position = -115 score = 5.20068 sequence = TACTGGTCAAACCAGAA Gene: VP0030: Enoyl-CoA hydratase (EC 4.2.1.17)	* Vibrio shilonii AK1 Site: position = -76 score = 5.11679 sequence = AACTGGTCTAACCAGAA Gene: VSAK1_12702: Enoyl-CoA hydratase (EC 4.2.1.17)	* Vibrio splendidus LGP32 Site: position = -87 score = 4.44046 sequence = AACTGGTCTTACCAGGT Gene: VS_0041: Enoyl-CoA hydratase (EC 4.2.1.17)	* Vibrio fischeri ES114 Site: position = -68 score = 5.58953 sequence = AACTGGTCAAACCAGAT Gene: VF_0025: Enoyl-CoA hydratase (EC 4.2.1.17)	* Vibrio salmonicida LFI1238 Site: position = -68 score = 4.5827 sequence = AACTGGTCAAACCAGGC Gene: VSAL_I2974: Enoyl-CoA hydratase (EC 4.2.1.17)	* Vibrio angustum S14 Site: position = -63 score = 5.45302 sequence = AACAGGTCAAACCAGTT Gene: VAS14_22297: Enoyl-CoA hydratase (EC 4.2.1.17)	* Photobacterium profundum SS9 Site: position = -59 score = 5.45302 sequence = AACAGGTCAAACCAGTT Gene: PBPRA0064: Enoyl-CoA hydratase (EC 4.2.1.17)	Enoyl-CoA hydratase (EC 4.2.1.17)
fadA	Vibrio cholerae O1 biovar eltor str. N16961 Gene: VC2759: 3-ketoacyl-CoA thiolase (EC 2.3.1.16)	Vibrio vulnificus CMCP6 Gene: VV1_0982: 3-ketoacyl-CoA thiolase (EC 2.3.1.16)	Vibrio harveyi ATCC BAA-1116 Gene: VIBHAR_00459: 3-ketoacyl-CoA thiolase (EC 2.3.1.16)	Vibrio parahaemolyticus RIMD 2210633 Gene: VP0029: 3-ketoacyl-CoA thiolase (EC 2.3.1.16)	Vibrio shilonii AK1 Gene: VSAK1_12697: 3-ketoacyl-CoA thiolase (EC 2.3.1.16)	Vibrio splendidus LGP32 Gene: VS_0040: 3-ketoacyl-CoA thiolase (EC 2.3.1.16)	Vibrio fischeri ES114 Gene: VF_0024: 3-ketoacyl-CoA thiolase (EC 2.3.1.16)	Vibrio salmonicida LFI1238 Gene: VSAL_I2973: 3-ketoacyl-CoA thiolase (EC 2.3.1.16)	Vibrio angustum S14 Gene: VAS14_22302: 3-ketoacyl-CoA thiolase (EC 2.3.1.16)	Photobacterium profundum SS9 Gene: PBPRA0063: 3-ketoacyl-CoA thiolase (EC 2.3.1.16)	3-ketoacyl-CoA thiolase (EC 2.3.1.16)

CRON 4.
plsB	* Vibrio cholerae O1 biovar eltor str. N16961 Site: position = -131 score = 4.60409 sequence = AAAAGGTTTGACCAGTT Gene: VC0093: Glycerol-3-phosphate acyltransferase (EC 2.3.1.15)	* Vibrio vulnificus CMCP6 Site: position = -131 score = 4.60409 sequence = AAAAGGTTTGACCAGTT Gene: VV1_1165: Glycerol-3-phosphate acyltransferase (EC 2.3.1.15)	* Vibrio harveyi ATCC BAA-1116 Site: position = -213 score = 4.60409 sequence = AAAAGGTTTGACCAGTT Gene: VIBHAR_00269: Glycerol-3-phosphate acyltransferase (EC 2.3.1.15)	* Vibrio parahaemolyticus RIMD 2210633 Site: position = -158 score = 4.60409 sequence = AAAAGGTTTGACCAGTT Gene: VP2947: Glycerol-3-phosphate acyltransferase (EC 2.3.1.15)	* Vibrio shilonii AK1 Site: position = -132 score = 4.7027 sequence = AAAAGGTAAGACCAGTT Gene: VSAK1_12467: Glycerol-3-phosphate acyltransferase (EC 2.3.1.15)	* Vibrio splendidus LGP32 Site: position = -148 score = 4.92943 sequence = AAAAGGTTAGACCAGTT Gene: VS_3009: Glycerol-3-phosphate acyltransferase (EC 2.3.1.15)	* Vibrio fischeri ES114 Site: position = -95 score = 4.60409 sequence = AAAAGGTTTGACCAGTT Gene: VF_2443: Glycerol-3-phosphate acyltransferase (EC 2.3.1.15)	* Vibrio salmonicida LFI1238 Site: position = -95 score = 4.60409 sequence = AAAAGGTTTGACCAGTT Gene: VSAL_I2894: Glycerol-3-phosphate acyltransferase (EC 2.3.1.15)	Vibrio angustum S14 Gene: VAS14_21842: Glycerol-3-phosphate acyltransferase (EC 2.3.1.15)	Photobacterium profundum SS9 Gene: PBPRA0164: Glycerol-3-phosphate acyltransferase (EC 2.3.1.15)	Glycerol-3-phosphate acyltransferase (EC 2.3.1.15)

CRON 5.
fadE2	* Vibrio cholerae O1 biovar eltor str. N16961 Site: position = -82 score = 5.69961 sequence = AACTGGTTAGACCACTA Gene: VC2231: Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.99.2)	* Vibrio vulnificus CMCP6 Site: position = -138 score = 3.84417 sequence = CTCTACTCAGATCACTT Site: position = -68 score = 5.54167 sequence = AACTGGTTTGACCTCTT Gene: VV1_1896: Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.99.2)	* Vibrio harveyi ATCC BAA-1116 Site: position = -67 score = 5.62556 sequence = TACTGGTTAGACCTCTT Gene: VIBHAR_03204: Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.99.2)	* Vibrio parahaemolyticus RIMD 2210633 Site: position = -67 score = 5.86701 sequence = AACTGGTTAGACCTCTT Gene: VP2289: Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.99.2)	* Vibrio shilonii AK1 Site: position = -83 score = 4.8106 sequence = TACTGGTACGACCTCTT Gene: VSAK1_07334: Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.99.2)	* Vibrio splendidus LGP32 Site: position = -63 score = 5.30374 sequence = GACTGGTTAGACCTCTT Gene: VS_2322: Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.99.2)	* Vibrio fischeri ES114 Site: position = -97 score = 5.86701 sequence = AACTGGTTAGACCTCTT Gene: VF_1932: Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.99.2)	* Vibrio salmonicida LFI1238 Site: position = -114 score = 5.25683 sequence = AACTAGTTAGACCTCTT Gene: VSAL_I2395: Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.99.2)	* Vibrio angustum S14 Site: position = -155 score = 5.31494 sequence = AAGTGGTAAGACCTCTT Gene: VAS14_00423: Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.99.2)	* Photobacterium profundum SS9 Site: position = -127 score = 5.31494 sequence = AAGTGGTAAGACCTCTT Gene: PBPRA2915: Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.99.2)	Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.99.2)

CRON 6.
VC2105	* Vibrio cholerae O1 biovar eltor str. N16961 Site: position = -109 score = 4.02288 sequence = AAGTGCTCTTACCAGTT Gene: VC2105: Thioesterase/thiol ester dehydrase-isomerase	Vibrio vulnificus CMCP6 Gene: VV1_0174: Thioesterase/thiol ester dehydrase-isomerase	* Vibrio harveyi ATCC BAA-1116 Site: position = -57 score = 4.79838 sequence = TACAGATCAGACCAGTT Gene: VIBHAR_01340: Thioesterase/thiol ester dehydrase-isomerase	* Vibrio parahaemolyticus RIMD 2210633 Site: position = -57 score = 4.47304 sequence = TACAGATCTGACCAGTT Gene: VP0834: Thioesterase/thiol ester dehydrase-isomerase	* Vibrio shilonii AK1 Site: position = -52 score = 4.71449 sequence = AACACGTCTGACCAGTT Gene: VSAK1_10623: Thioesterase/thiol ester dehydrase-isomerase	Vibrio splendidus LGP32 Gene: VS_2257: Thioesterase/thiol ester dehydrase-isomerase	* Vibrio fischeri ES114 Site: position = -32 score = 4.68894 sequence = ATGAGGTCTGACCAGAA Gene: VF_0811: Thioesterase/thiol ester dehydrase-isomerase	* Vibrio salmonicida LFI1238 Site: position = -33 score = 4.68894 sequence = ATGAGGTCTGACCAGAA Gene: VSAL_I0834: Thioesterase/thiol ester dehydrase-isomerase	Vibrio angustum S14 Gene: VAS14_17681: Thioesterase/thiol ester dehydrase-isomerase	Photobacterium profundum SS9	Thioesterase/thiol ester dehydrase-isomerase

CRON 7.
fadH	* Vibrio cholerae O1 biovar eltor str. N16961 Site: position = -42 score = 5.21583 sequence = TTCTGGTCAGACCATAT Gene: VC1993: 2,4-dienoyl-CoA reductase [NADPH] (EC 1.3.1.34)	* Vibrio vulnificus CMCP6 Site: position = -38 score = 4.49816 sequence = CTCTGGTCTGACCACGA Gene: VV1_3132: 2,4-dienoyl-CoA reductase [NADPH] (EC 1.3.1.34)	* Vibrio harveyi ATCC BAA-1116 Site: position = -39 score = 4.95561 sequence = CTGTGGTCAGACCACAA Gene: VIBHAR_03043: 2,4-dienoyl-CoA reductase [NADPH] (EC 1.3.1.34)	* Vibrio parahaemolyticus RIMD 2210633 Site: position = -48 score = 4.28916 sequence = GTCTGGTCAGACCATGA Gene: VP2151: 2,4-dienoyl-CoA reductase [NADPH] (EC 1.3.1.34)	* Vibrio shilonii AK1 Site: position = -43 score = 5.42752 sequence = TTCTGGTCAGACCACAA Gene: VSAK1_03494: 2,4-dienoyl-CoA reductase [NADPH] (EC 1.3.1.34)	* Vibrio splendidus LGP32 Site: position = -33 score = 4.77684 sequence = TTGTGGTCTGACCACAA Gene: VS_0938: 2,4-dienoyl-CoA reductase [NADPH] (EC 1.3.1.34)	* Vibrio fischeri ES114 Site: position = -39 score = 5.42752 sequence = TTCTGGTCAGACCACAA Gene: VF_1642: 2,4-dienoyl-CoA reductase [NADPH] (EC 1.3.1.34)	* Vibrio salmonicida LFI1238 Site: position = -39 score = 5.10218 sequence = TTCTGGTCTGACCACAA Gene: VSAL_I2156: 2,4-dienoyl-CoA reductase [NADPH] (EC 1.3.1.34)	* Vibrio angustum S14 Site: position = -37 score = 5.17095 sequence = TACTGGTCAGACCATAA Gene: VAS14_05978: 2,4-dienoyl-CoA reductase [NADPH] (EC 1.3.1.34)	* Photobacterium profundum SS9 Site: position = -36 score = 5.17095 sequence = TACTGGTCAGACCATAA Gene: PBPRA2594: 2,4-dienoyl-CoA reductase [NADPH] (EC 1.3.1.34)	2,4-dienoyl-CoA reductase [NADPH] (EC 1.3.1.34)

CRON 8.
fadI	Vibrio cholerae O1 biovar eltor str. N16961 Gene: VC1046: 3-ketoacyl-CoA thiolase (EC 2.3.1.16)	* Vibrio vulnificus CMCP6 Site: position = -34 score = 5.69985 sequence = ATCAGGTCAGACCTCTT Gene: VV1_1975: 3-ketoacyl-CoA thiolase (EC 2.3.1.16)	* Vibrio harveyi ATCC BAA-1116 Site: position = -34 score = 5.69985 sequence = ATCAGGTCAGACCTCTT Gene: VIBHAR_03121: 3-ketoacyl-CoA thiolase (EC 2.3.1.16)	* Vibrio parahaemolyticus RIMD 2210633 Site: position = -34 score = 5.69985 sequence = ATCAGGTCAGACCTCTT Gene: VP2209: 3-ketoacyl-CoA thiolase (EC 2.3.1.16)	* Vibrio shilonii AK1 Site: position = -31 score = 5.18349 sequence = CTGTGGTCAGACCTCTT Gene: VSAK1_03244: 3-ketoacyl-CoA thiolase (EC 2.3.1.16)	* Vibrio splendidus LGP32 Site: position = -34 score = 5.45841 sequence = TTCAGGTCAGACCTCTT Gene: VS_0864: 3-ketoacyl-CoA thiolase (EC 2.3.1.16)	* Vibrio fischeri ES114 Site: position = -39 score = 4.26979 sequence = TTGAGGTCTGACCACCT Gene: VF_1811: 3-ketoacyl-CoA thiolase (EC 2.3.1.16)	* Vibrio salmonicida LFI1238 Site: position = -43 score = 4.64033 sequence = TTGAGGTCTGACCACTA Gene: VSAL_I2268: 3-ketoacyl-CoA thiolase (EC 2.3.1.16)	* Vibrio angustum S14 Site: position = -71 score = 4.33851 sequence = GTGAGGTCTGACCTCTA Gene: VAS14_17336: 3-ketoacyl-CoA thiolase (EC 2.3.1.16)	* Photobacterium profundum SS9 Site: position = -91 score = 4.85733 sequence = TTGTGGTCTGACCTCTA Gene: PBPRA0961: 3-ketoacyl-CoA thiolase (EC 2.3.1.16)	3-ketoacyl-CoA thiolase (EC 2.3.1.16)
fadJ	Vibrio cholerae O1 biovar eltor str. N16961 Gene: VC1047: Enoyl-CoA hydratase (EC 4.2.1.17)	Vibrio vulnificus CMCP6 Gene: VV1_1976: Enoyl-CoA hydratase (EC 4.2.1.17)	Vibrio harveyi ATCC BAA-1116 Gene: VIBHAR_03120: Enoyl-CoA hydratase (EC 4.2.1.17)	Vibrio parahaemolyticus RIMD 2210633 Gene: VP2208: Enoyl-CoA hydratase (EC 4.2.1.17)	Vibrio shilonii AK1 Gene: VSAK1_03249: Enoyl-CoA hydratase (EC 4.2.1.17)	Vibrio splendidus LGP32 Gene: VS_0865: Enoyl-CoA hydratase (EC 4.2.1.17)	Vibrio fischeri ES114 Gene: VF_1810: Enoyl-CoA hydratase (EC 4.2.1.17)	Vibrio salmonicida LFI1238	Vibrio angustum S14 Gene: VAS14_17341: Enoyl-CoA hydratase (EC 4.2.1.17)	Photobacterium profundum SS9 Gene: PBPRA0962: Enoyl-CoA hydratase (EC 4.2.1.17)	Enoyl-CoA hydratase (EC 4.2.1.17)

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog FadR - Vibrionales

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --