Collection of regulogs in Caulobacterales taxonomic group
Genomes | 4 |
TF regulogs | 33 |
TF regulons | 100 |
TF binding sites | 430 |
RNA regulogs | 8 |
RNA regulons | 26 |
RNA sites | 36 |
This collection involves all regulons that were tentatively predicted by applying integrative comparative genomic approach to a single taxonomic group of closely-related genomes. To infer the regulons operated by transcription factors (TFs), we combined the identification of TF binding sites and cross-genome comparison of regulons with the analysis of the genomic and functional context of candidate target genes. To infer the regulons operated by regulatory RNAs such as riboswitches, we identified candidate RNA regulatory elements using HMM profiles and further analyzed their genomic and functional context.
TF | RNA | Total | ||||
---|---|---|---|---|---|---|
Genomes | Regulons | Sites | Regulons | Sites | Regulons | Sites |
Caulobacter crescentus CB15 | 24 | 119 | 6 | 10 | 30 | 129 |
Caulobacter segnis ATCC 21756 | 25 | 119 | 6 | 9 | 31 | 128 |
Caulobacter sp. K31 | 29 | 119 | 7 | 9 | 36 | 128 |
Phenylobacterium zucineum HLK1 | 22 | 73 | 7 | 8 | 29 | 81 |
Family | Type | Regulator | Function | ||||
---|---|---|---|---|---|---|---|
ArsR | TF | SahR |
4
SahR
Caulobacter crescentus CB15 |
4
SahR
Caulobacter segnis ATCC 21756 |
3
SahR
Caulobacter sp. K31 |
3
SahR
Phenylobacterium zucineum HLK1 |
Methionine metabolism |
CRP | TF | FixK |
6
FixK
Caulobacter crescentus CB15 |
7
FixK
Caulobacter segnis ATCC 21756 |
5
FixK
Caulobacter sp. K31 |
3
FixK
Phenylobacterium zucineum HLK1 |
Oxidative stress response; Nitrogen fixation |
TF | NnrR |
4
NnrR
Caulobacter segnis ATCC 21756 |
5
NnrR
Phenylobacterium zucineum HLK1 |
Denitrification | |||
FUR | TF | Fur |
9
Fur
Caulobacter crescentus CB15 |
9
Fur
Caulobacter segnis ATCC 21756 |
7
Fur
Caulobacter sp. K31 |
7
Fur
Phenylobacterium zucineum HLK1 |
Iron homeostasis |
TF | Zur |
6
Zur
Caulobacter crescentus CB15 |
5
Zur
Caulobacter segnis ATCC 21756 |
3
Zur
Caulobacter sp. K31 |
2
Zur
Phenylobacterium zucineum HLK1 |
Zinc homeostasis | |
Fis | TF | NtrC |
4
NtrC
Caulobacter crescentus CB15 |
2
NtrC
Caulobacter segnis ATCC 21756 |
4
NtrC
Caulobacter sp. K31 |
3
NtrC
Phenylobacterium zucineum HLK1 |
Nitrogen assimilation |
GntR/MocR | TF | PdxQ2 |
3
PdxQ2
Caulobacter segnis ATCC 21756 |
3
PdxQ2
Caulobacter sp. K31 |
Metabolite transport; Pyridoxine/pyridoxal homeostasis | ||
TF | PdxR3 |
1
PdxR3
Phenylobacterium zucineum HLK1 |
Pyridoxine/pyridoxal homeostasis | ||||
TF | PdxW |
2
PdxW
Phenylobacterium zucineum HLK1 |
Pyridoxine/pyridoxal homeostasis | ||||
TF | YrdX3 |
1
YrdX3
Caulobacter crescentus CB15 |
1
YrdX3
Caulobacter segnis ATCC 21756 |
1
YrdX3
Caulobacter sp. K31 |
|||
GntR/Others | TF | HutC |
2
HutC
Caulobacter crescentus CB15 |
2
HutC
Caulobacter segnis ATCC 21756 |
3
HutC
Caulobacter sp. K31 |
3
HutC
Phenylobacterium zucineum HLK1 |
Histidine utilization |
TF | NagQ |
5
NagQ
Caulobacter crescentus CB15 |
4
NagQ
Caulobacter segnis ATCC 21756 |
2
NagQ
Caulobacter sp. K31 |
N-acetylglucosamine utilization | ||
TF | PhnR |
3
PhnR
Caulobacter segnis ATCC 21756 |
4
PhnR
Caulobacter sp. K31 |
Phosphonate utilization; 2-aminoethylphosphonate utilization | |||
TF | VanR |
2
VanR
Caulobacter crescentus CB15 |
2
VanR
Caulobacter segnis ATCC 21756 |
1
VanR
Caulobacter sp. K31 |
Vanillate utilization | ||
HrcA | TF | HrcA |
1
HrcA
Caulobacter crescentus CB15 |
1
HrcA
Caulobacter segnis ATCC 21756 |
1
HrcA
Caulobacter sp. K31 |
1
HrcA
Phenylobacterium zucineum HLK1 |
Heat shock response |
LacI | TF | BglR1 |
1
BglR1
Caulobacter crescentus CB15 |
1
BglR1
Caulobacter sp. K31 |
Beta-glucosides utilization | ||
TF | BglR2 |
3
BglR2
Caulobacter crescentus CB15 |
3
BglR2
Caulobacter segnis ATCC 21756 |
3
BglR2
Caulobacter sp. K31 |
Beta-glucosides utilization | ||
TF | BglR3 |
2
BglR3
Caulobacter crescentus CB15 |
2
BglR3
Caulobacter segnis ATCC 21756 |
2
BglR3
Caulobacter sp. K31 |
2
BglR3
Phenylobacterium zucineum HLK1 |
Beta-glucosides utilization | |
TF | CC1627 |
4
CC1627
Caulobacter crescentus CB15 |
3
CC1627
Caulobacter segnis ATCC 21756 |
5
CC1627
Caulobacter sp. K31 |
2
CC1627
Phenylobacterium zucineum HLK1 |
Sugar utilization | |
TF | GluR |
6
GluR
Caulobacter crescentus CB15 |
6
GluR
Caulobacter segnis ATCC 21756 |
5
GluR
Caulobacter sp. K31 |
Carbohydrate metabolism | ||
LexA | TF | LexA |
12
LexA
Caulobacter crescentus CB15 |
11
LexA
Caulobacter segnis ATCC 21756 |
10
LexA
Caulobacter sp. K31 |
10
LexA
Phenylobacterium zucineum HLK1 |
SOS response |
LuxR | TF | FixJ |
1
FixJ
Caulobacter crescentus CB15 |
1
FixJ
Caulobacter segnis ATCC 21756 |
1
FixJ
Caulobacter sp. K31 |
1
FixJ
Phenylobacterium zucineum HLK1 |
Oxidative stress response |
MerR | TF | CadR-PbrR |
1
CadR-PbrR
Caulobacter sp. K31 |
2
CadR-PbrR
Phenylobacterium zucineum HLK1 |
Lead resistance; Cadmium resistance | ||
TF | CueR |
3
CueR
Caulobacter sp. K31 |
4
CueR
Phenylobacterium zucineum HLK1 |
Copper resistance | |||
TF | LiuR |
2
LiuR
Caulobacter crescentus CB15 |
2
LiuR
Caulobacter segnis ATCC 21756 |
3
LiuR
Caulobacter sp. K31 |
2
LiuR
Phenylobacterium zucineum HLK1 |
Branched-chain amino acid degradation | |
TF | ZntR |
1
ZntR
Caulobacter sp. K31 |
Zinc resistance | ||||
ModE | TF | ModE |
2
ModE
Caulobacter crescentus CB15 |
3
ModE
Caulobacter sp. K31 |
Molybdenum homeostasis | ||
NadQ | TF | NadQ |
3
NadQ
Caulobacter crescentus CB15 |
3
NadQ
Caulobacter segnis ATCC 21756 |
3
NadQ
Caulobacter sp. K31 |
3
NadQ
Phenylobacterium zucineum HLK1 |
NAD biosynthesis |
NrdR | TF | NrdR |
3
NrdR
Caulobacter crescentus CB15 |
3
NrdR
Caulobacter segnis ATCC 21756 |
3
NrdR
Caulobacter sp. K31 |
3
NrdR
Phenylobacterium zucineum HLK1 |
Deoxyribonucleotide biosynthesis |
Rrf2 | TF | IscR |
1
IscR
Caulobacter crescentus CB15 |
1
IscR
Caulobacter segnis ATCC 21756 |
1
IscR
Caulobacter sp. K31 |
1
IscR
Phenylobacterium zucineum HLK1 |
Iron-sulfur cluster biogenesis |
TF | NsrR |
2
NsrR
Caulobacter sp. K31 |
1
NsrR
Phenylobacterium zucineum HLK1 |
Nitrosative stress response | |||
TetR | TF | PsrA |
22
PsrA
Caulobacter crescentus CB15 |
19
PsrA
Caulobacter segnis ATCC 21756 |
21
PsrA
Caulobacter sp. K31 |
6
PsrA
Phenylobacterium zucineum HLK1 |
Fatty acid degradation |
TF | RutR |
2
RutR
Caulobacter crescentus CB15 |
2
RutR
Caulobacter segnis ATCC 21756 |
Pyrimidine utilization | |||
RF00050 | RNA | FMN |
1
FMN
Phenylobacterium zucineum HLK1 |
Riboflavin biosynthesis | |||
RF00059 | RNA | TPP |
1
TPP
Caulobacter crescentus CB15 |
1
TPP
Caulobacter segnis ATCC 21756 |
1
TPP
Caulobacter sp. K31 |
1
TPP
Phenylobacterium zucineum HLK1 |
Thiamine biosynthesis |
RF00080 | RNA | yybP-ykoY |
1
yybP-ykoY
Caulobacter crescentus CB15 |
1
yybP-ykoY
Caulobacter segnis ATCC 21756 |
1
yybP-ykoY
Caulobacter sp. K31 |
1
yybP-ykoY
Phenylobacterium zucineum HLK1 |
|
RF00174 | RNA | Cobalamin |
2
Cobalamin
Caulobacter crescentus CB15 |
3
Cobalamin
Caulobacter segnis ATCC 21756 |
1
Cobalamin
Caulobacter sp. K31 |
1
Cobalamin
Phenylobacterium zucineum HLK1 |
Cobalamin biosynthesis |
RF00504 | RNA | Glycine |
2
Glycine
Caulobacter crescentus CB15 |
1
Glycine
Caulobacter segnis ATCC 21756 |
2
Glycine
Caulobacter sp. K31 |
1
Glycine
Phenylobacterium zucineum HLK1 |
Glycine metabolism |
RF00517 | RNA | serC |
1
serC
Caulobacter crescentus CB15 |
1
serC
Caulobacter segnis ATCC 21756 |
1
serC
Caulobacter sp. K31 |
1
serC
Phenylobacterium zucineum HLK1 |
Serine biosynthesis |
RF01055 | RNA | MOCO_RNA_motif |
1
MOCO_RNA_motif
Caulobacter sp. K31 |
Molybdopterin biosynthesis; Molybdenum homeostasis | |||
RF01068 | RNA | mini-ykkC |
1
mini-ykkC
Caulobacter crescentus CB15 |
1
mini-ykkC
Caulobacter segnis ATCC 21756 |
1
mini-ykkC
Caulobacter sp. K31 |
1
mini-ykkC
Phenylobacterium zucineum HLK1 |
Multidrug resistance |