Collection of regulogs in Thermoanaerobacterales taxonomic group
Genomes | 7 |
TF regulogs | 16 |
TF regulons | 71 |
TF binding sites | 146 |
RNA regulogs | 3 |
RNA regulons | 19 |
RNA sites | 32 |
This collection involves all regulons that were tentatively predicted by applying integrative comparative genomic approach to a single taxonomic group of closely-related genomes. To infer the regulons operated by transcription factors (TFs), we combined the identification of TF binding sites and cross-genome comparison of regulons with the analysis of the genomic and functional context of candidate target genes. To infer the regulons operated by regulatory RNAs such as riboswitches, we identified candidate RNA regulatory elements using HMM profiles and further analyzed their genomic and functional context.
TF | RNA | Total | ||||
---|---|---|---|---|---|---|
Genomes | Regulons | Sites | Regulons | Sites | Regulons | Sites |
Anaerocellum thermophilum DSM 6725 | 13 | 27 | 3 | 3 | 16 | 30 |
Caldicellulosiruptor saccharolyticus DSM 8903 | 13 | 26 | 3 | 3 | 16 | 29 |
Carboxydothermus hydrogenoformans Z-2901 | 6 | 10 | 3 | 5 | 9 | 15 |
Moorella thermoacetica ATCC 39073 | 5 | 10 | 3 | 6 | 8 | 16 |
Thermoanaerobacter ethanolicus X514 | 12 | 25 | 3 | 6 | 15 | 31 |
Thermoanaerobacter italicus Ab9 | 10 | 23 | 2 | 5 | 12 | 28 |
Thermoanaerobacter tengcongensis MB4 | 12 | 25 | 2 | 4 | 14 | 29 |
Family | Type | Regulator | Function | |||||||
---|---|---|---|---|---|---|---|---|---|---|
ArgR | TF | ArgR |
1
ArgR
Thermoanaerobacter ethanolicus X514 |
1
ArgR
Thermoanaerobacter italicus Ab9 |
2
ArgR
Thermoanaerobacter tengcongensis MB4 |
3
ArgR
Caldicellulosiruptor saccharolyticus DSM 8903 |
1
ArgR
Carboxydothermus hydrogenoformans Z-2901 |
3
ArgR
Anaerocellum thermophilum DSM 6725 |
1
ArgR
Moorella thermoacetica ATCC 39073 |
Arginine biosynthesis |
BirA | TF | BirA |
1
BirA
Thermoanaerobacter ethanolicus X514 |
1
BirA
Thermoanaerobacter italicus Ab9 |
1
BirA
Thermoanaerobacter tengcongensis MB4 |
3
BirA
Caldicellulosiruptor saccharolyticus DSM 8903 |
2
BirA
Carboxydothermus hydrogenoformans Z-2901 |
3
BirA
Anaerocellum thermophilum DSM 6725 |
Biotin biosynthesis | |
CRP | TF | HcpR |
2
HcpR
Caldicellulosiruptor saccharolyticus DSM 8903 |
2
HcpR
Anaerocellum thermophilum DSM 6725 |
Nitrosative stress response | |||||
FUR | TF | Fur |
5
Fur
Thermoanaerobacter ethanolicus X514 |
5
Fur
Thermoanaerobacter italicus Ab9 |
6
Fur
Thermoanaerobacter tengcongensis MB4 |
2
Fur
Caldicellulosiruptor saccharolyticus DSM 8903 |
2
Fur
Carboxydothermus hydrogenoformans Z-2901 |
2
Fur
Anaerocellum thermophilum DSM 6725 |
2
Fur
Moorella thermoacetica ATCC 39073 |
Iron homeostasis |
GntR/MocR | TF | PdxR |
2
PdxR
Caldicellulosiruptor saccharolyticus DSM 8903 |
2
PdxR
Anaerocellum thermophilum DSM 6725 |
Pyridoxine biosynthesis | |||||
GntR/Others | TF | Csac_2166 |
1
Csac_2166
Thermoanaerobacter ethanolicus X514 |
1
Csac_2166
Thermoanaerobacter tengcongensis MB4 |
1
Csac_2166
Caldicellulosiruptor saccharolyticus DSM 8903 |
1
Csac_2166
Carboxydothermus hydrogenoformans Z-2901 |
1
Csac_2166
Anaerocellum thermophilum DSM 6725 |
Multidrug resistance; Multidrug efflux | ||
TF | Csac_2497 |
1
Csac_2497
Caldicellulosiruptor saccharolyticus DSM 8903 |
1
Csac_2497
Anaerocellum thermophilum DSM 6725 |
Multidrug resistance; Multidrug efflux | ||||||
TF | YhcF |
1
YhcF
Caldicellulosiruptor saccharolyticus DSM 8903 |
1
YhcF
Anaerocellum thermophilum DSM 6725 |
1
YhcF
Moorella thermoacetica ATCC 39073 |
Metabolite transport; Multidrug efflux; Multidrug resistance | |||||
HrcA | TF | HrcA |
2
HrcA
Thermoanaerobacter ethanolicus X514 |
2
HrcA
Thermoanaerobacter italicus Ab9 |
2
HrcA
Thermoanaerobacter tengcongensis MB4 |
2
HrcA
Caldicellulosiruptor saccharolyticus DSM 8903 |
2
HrcA
Carboxydothermus hydrogenoformans Z-2901 |
2
HrcA
Anaerocellum thermophilum DSM 6725 |
3
HrcA
Moorella thermoacetica ATCC 39073 |
Heat shock response |
LacI | TF | IolR |
1
IolR
Thermoanaerobacter ethanolicus X514 |
1
IolR
Thermoanaerobacter italicus Ab9 |
1
IolR
Thermoanaerobacter tengcongensis MB4 |
1
IolR
Caldicellulosiruptor saccharolyticus DSM 8903 |
1
IolR
Anaerocellum thermophilum DSM 6725 |
Inositol utilization | ||
TF | KojR |
2
KojR
Thermoanaerobacter ethanolicus X514 |
2
KojR
Thermoanaerobacter italicus Ab9 |
2
KojR
Thermoanaerobacter tengcongensis MB4 |
2
KojR
Caldicellulosiruptor saccharolyticus DSM 8903 |
2
KojR
Anaerocellum thermophilum DSM 6725 |
Kojibiose utilization | |||
TF | MalR2 |
3
MalR2
Thermoanaerobacter ethanolicus X514 |
3
MalR2
Thermoanaerobacter italicus Ab9 |
3
MalR2
Thermoanaerobacter tengcongensis MB4 |
2
MalR2
Caldicellulosiruptor saccharolyticus DSM 8903 |
2
MalR2
Anaerocellum thermophilum DSM 6725 |
Maltose utilization; Maltodextrin utilization | |||
TF | RbsR |
1
RbsR
Thermoanaerobacter ethanolicus X514 |
1
RbsR
Thermoanaerobacter tengcongensis MB4 |
Ribose utilization | ||||||
TF | TreR |
2
TreR
Thermoanaerobacter ethanolicus X514 |
2
TreR
Thermoanaerobacter italicus Ab9 |
2
TreR
Thermoanaerobacter tengcongensis MB4 |
Trehalose utilization | |||||
NikR | TF | NikR |
1
NikR
Thermoanaerobacter ethanolicus X514 |
1
NikR
Thermoanaerobacter italicus Ab9 |
1
NikR
Thermoanaerobacter tengcongensis MB4 |
Nickel homeostasis | ||||
TrpR | TF | HisR |
1
HisR
Thermoanaerobacter ethanolicus X514 |
1
HisR
Thermoanaerobacter italicus Ab9 |
1
HisR
Thermoanaerobacter tengcongensis MB4 |
1
HisR
Caldicellulosiruptor saccharolyticus DSM 8903 |
2
HisR
Carboxydothermus hydrogenoformans Z-2901 |
1
HisR
Anaerocellum thermophilum DSM 6725 |
1
HisR
Moorella thermoacetica ATCC 39073 |
Histidine biosynthesis |
RF00050 | RNA | FMN |
2
FMN
Thermoanaerobacter ethanolicus X514 |
2
FMN
Thermoanaerobacter italicus Ab9 |
1
FMN
Thermoanaerobacter tengcongensis MB4 |
1
FMN
Caldicellulosiruptor saccharolyticus DSM 8903 |
1
FMN
Carboxydothermus hydrogenoformans Z-2901 |
1
FMN
Anaerocellum thermophilum DSM 6725 |
1
FMN
Moorella thermoacetica ATCC 39073 |
Riboflavin biosynthesis |
RF00059 | RNA | TPP |
3
TPP
Thermoanaerobacter ethanolicus X514 |
3
TPP
Thermoanaerobacter italicus Ab9 |
3
TPP
Thermoanaerobacter tengcongensis MB4 |
1
TPP
Caldicellulosiruptor saccharolyticus DSM 8903 |
3
TPP
Carboxydothermus hydrogenoformans Z-2901 |
1
TPP
Anaerocellum thermophilum DSM 6725 |
3
TPP
Moorella thermoacetica ATCC 39073 |
Thiamine biosynthesis |
RF01055 | RNA | MOCO_RNA_motif |
1
MOCO_RNA_motif
Thermoanaerobacter ethanolicus X514 |
1
MOCO_RNA_motif
Caldicellulosiruptor saccharolyticus DSM 8903 |
1
MOCO_RNA_motif
Carboxydothermus hydrogenoformans Z-2901 |
1
MOCO_RNA_motif
Anaerocellum thermophilum DSM 6725 |
2
MOCO_RNA_motif
Moorella thermoacetica ATCC 39073 |
Molybdopterin biosynthesis; Molybdenum homeostasis |