Regulog Fur - Thermoanaerobacterales

Properties
Regulator type:	Transcription factor
Regulator family:	FUR
Regulation mode:	repressor
Biological process:	Iron homeostasis
Effector:	Iron ion, (Fe2+)
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 29 sites [see more]

Member of regulog collections

By taxonomy - Thermoanaerobacterales
By trascription factor - FUR
By TF family - FUR
By effector - Iron ion, (Fe2+)
By pathway - Iron homeostasis

Statistics of regulated genes
Genome	Genes	Operons
Thermoanaerobacter ethanolicus X514	12	5
Thermoanaerobacter italicus Ab9	12	5
Thermoanaerobacter tengcongensis MB4	13	6
Caldicellulosiruptor saccharolyticus DSM 8903	3	2
Carboxydothermus hydrogenoformans Z-2901	2	2
Anaerocellum thermophilum DSM 6725	3	2
Moorella thermoacetica ATCC 39073	4	2

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes								Function

CRON 1.
ftn	* Thermoanaerobacter ethanolicus X514 Site: position = 78 score = 5.41456 sequence = ATGGAAAATTATTTTCAAG Gene: Teth514_0668: Ferritin, Dps family protein	Thermoanaerobacter italicus Ab9	* Thermoanaerobacter tengcongensis MB4 Site: position = 78 score = 5.3215 sequence = ATGGAGAATTATTTTCAAG Gene: TTE0959: Ferritin, Dps family protein	Caldicellulosiruptor saccharolyticus DSM 8903 Gene: Csac_2712: Ferritin, Dps family protein	Carboxydothermus hydrogenoformans Z-2901	Anaerocellum thermophilum DSM 6725 Gene: Athe_1983: Ferritin, Dps family protein	Moorella thermoacetica ATCC 39073	Ferritin, Dps family protein

CRON 2.
mmt1	Thermoanaerobacter ethanolicus X514	* Thermoanaerobacter italicus Ab9 Site: position = -110 score = 5.57969 sequence = ATTGAATTTGATTTTCAAT Gene: Thit_0093: Cobalt-zinc-cadmium resistance protein	* Thermoanaerobacter tengcongensis MB4 Site: position = -109 score = 5.57969 sequence = ATTGAAGTTGATTTTCAAT Gene: TTE0105: Cobalt-zinc-cadmium resistance protein	Caldicellulosiruptor saccharolyticus DSM 8903 Gene: Csac_0826: Cobalt-zinc-cadmium resistance protein	* Carboxydothermus hydrogenoformans Z-2901 Site: position = -145 score = 5.46027 sequence = ATTGAAAATGATTTTTAGT Gene: CHY_0502: Cobalt-zinc-cadmium resistance protein	Anaerocellum thermophilum DSM 6725 Gene: Athe_0589: Cobalt-zinc-cadmium resistance protein	Moorella thermoacetica ATCC 39073 Gene: Moth_1683: Cobalt-zinc-cadmium resistance protein	Cobalt-zinc-cadmium resistance protein

CRON 3.
ftr	Thermoanaerobacter ethanolicus X514	Thermoanaerobacter italicus Ab9	Thermoanaerobacter tengcongensis MB4	* Caldicellulosiruptor saccharolyticus DSM 8903 Site: position = -37 score = 5.75717 sequence = AGTGAAAATCAATTTCAAA Site: position = -43 score = 5.33364 sequence = ATTGAAAGTGAAAATCAAT Gene: Csac_0536: High-affinity Fe2+ permease, FTR family	* Carboxydothermus hydrogenoformans Z-2901 Site: position = -36 score = 6.59302 sequence = ATTGAAAATGATTTTCAAT Gene: CHY_2414: High-affinity Fe2+ permease, FTR family	* Anaerocellum thermophilum DSM 6725 Site: position = -40 score = 6.02365 sequence = AATGAAAATCAATTTCAAA Site: position = -46 score = 5.91647 sequence = ATTGAAAATGAAAATCAAT Gene: Athe_2602: High-affinity Fe2+ permease, FTR family	Moorella thermoacetica ATCC 39073	High-affinity Fe2+ permease, FTR family

CRON 4.
fur	* Thermoanaerobacter ethanolicus X514 Site: position = -56 score = 6.14323 sequence = ATTGAAAATGAATATCATA Gene: Teth514_1493: Transcriptional regulator for iron transport and metabolism, Fur family	* Thermoanaerobacter italicus Ab9 Site: position = -55 score = 6.14323 sequence = ATTGAAAATGAATATCATA Gene: Thit_1045: Transcriptional regulator for iron transport and metabolism, Fur family	* Thermoanaerobacter tengcongensis MB4 Site: position = -56 score = 6.14323 sequence = ATTGAAAATGAATATCATA Gene: TTE1252: Transcriptional regulator for iron transport and metabolism, Fur family	Caldicellulosiruptor saccharolyticus DSM 8903 Gene: Csac_1741: Transcriptional regulator for iron transport and metabolism, Fur family	Carboxydothermus hydrogenoformans Z-2901 Gene: CHY_2099: Transcriptional regulator for iron transport and metabolism, Fur family	Anaerocellum thermophilum DSM 6725 Gene: Athe_1562: Transcriptional regulator for iron transport and metabolism, Fur family	Moorella thermoacetica ATCC 39073 Gene: Moth_1147: Transcriptional regulator for iron transport and metabolism, Fur family	Transcriptional regulator for iron transport and metabolism, Fur family

CRON 5.
feoA3	* Thermoanaerobacter ethanolicus X514 Site: position = -128 score = 6.09193 sequence = AATGAGAAATATTATCAAT Site: position = -105 score = 5.11256 sequence = TTTGTAATTTATTTTCAAT Gene: Teth514_1138: Ferrous iron transport protein A	* Thermoanaerobacter italicus Ab9 Site: position = -128 score = 6.09193 sequence = AATGAGAAATATTATCAAT Site: position = -105 score = 5.11256 sequence = TTTGTAATTTATTTTCAAT Gene: Thit_1667: Ferrous iron transport protein A	* Thermoanaerobacter tengcongensis MB4 Site: position = -71 score = 6.19691 sequence = AATGAGAATTATTCTCAAT Gene: TTE1861: Ferrous iron transport protein A	Caldicellulosiruptor saccharolyticus DSM 8903	Carboxydothermus hydrogenoformans Z-2901	Anaerocellum thermophilum DSM 6725	* Moorella thermoacetica ATCC 39073 Site: position = -79 score = 5.83584 sequence = AATGAGAATGAATGTCATT Gene: Moth_1435: Ferrous iron transport protein A	Ferrous iron transport protein A
feoA2	Thermoanaerobacter ethanolicus X514 Gene: Teth514_1139: Ferrous iron transport protein A	Thermoanaerobacter italicus Ab9 Gene: Thit_1666: Ferrous iron transport protein A	Thermoanaerobacter tengcongensis MB4 Gene: TTE1860: Ferrous iron transport protein A	Caldicellulosiruptor saccharolyticus DSM 8903	Carboxydothermus hydrogenoformans Z-2901	Anaerocellum thermophilum DSM 6725	Moorella thermoacetica ATCC 39073 Gene: Moth_1434: Ferrous iron transport protein A	Ferrous iron transport protein A
feoB2	Thermoanaerobacter ethanolicus X514 Gene: Teth514_1140: Ferrous iron transport protein B	Thermoanaerobacter italicus Ab9 Gene: Thit_1665: Ferrous iron transport protein B	Thermoanaerobacter tengcongensis MB4 Gene: TTE1858: Ferrous iron transport protein B	Caldicellulosiruptor saccharolyticus DSM 8903	Carboxydothermus hydrogenoformans Z-2901	Anaerocellum thermophilum DSM 6725	Moorella thermoacetica ATCC 39073	Ferrous iron transport protein B

CRON 6.
sufC	* Thermoanaerobacter ethanolicus X514 Site: position = -120 score = 6.41031 sequence = AATGAAAATAATTATCAAT Gene: Teth514_2332: Iron-sulfur cluster assembly ATPase protein SufC	* Thermoanaerobacter italicus Ab9 Site: position = -119 score = 6.41031 sequence = AATGAAAATAATTATCAAT Gene: Thit_2296: Iron-sulfur cluster assembly ATPase protein SufC	* Thermoanaerobacter tengcongensis MB4 Site: position = -120 score = 5.27755 sequence = AAAGAAAATAATTATCAAC Gene: TTE2673: Iron-sulfur cluster assembly ATPase protein SufC	Caldicellulosiruptor saccharolyticus DSM 8903	Carboxydothermus hydrogenoformans Z-2901	Anaerocellum thermophilum DSM 6725	Moorella thermoacetica ATCC 39073	Iron-sulfur cluster assembly ATPase protein SufC
sufB	Thermoanaerobacter ethanolicus X514 Gene: Teth514_2331: Iron-sulfur cluster assembly protein SufB	Thermoanaerobacter italicus Ab9 Gene: Thit_2295: Iron-sulfur cluster assembly protein SufB	Thermoanaerobacter tengcongensis MB4 Gene: TTE2672: Iron-sulfur cluster assembly protein SufB	Caldicellulosiruptor saccharolyticus DSM 8903	Carboxydothermus hydrogenoformans Z-2901	Anaerocellum thermophilum DSM 6725	Moorella thermoacetica ATCC 39073	Iron-sulfur cluster assembly protein SufB
sufD	Thermoanaerobacter ethanolicus X514 Gene: Teth514_2330: Iron-sulfur cluster assembly protein SufD	Thermoanaerobacter italicus Ab9 Gene: Thit_2294: Iron-sulfur cluster assembly protein SufD	Thermoanaerobacter tengcongensis MB4 Gene: TTE2671: Iron-sulfur cluster assembly protein SufD	Caldicellulosiruptor saccharolyticus DSM 8903	Carboxydothermus hydrogenoformans Z-2901	Anaerocellum thermophilum DSM 6725	Moorella thermoacetica ATCC 39073	Iron-sulfur cluster assembly protein SufD
sufS	Thermoanaerobacter ethanolicus X514 Gene: Teth514_2329: Cysteine desulfurase (EC 2.8.1.7), SufS subfamily	Thermoanaerobacter italicus Ab9 Gene: Thit_2293: Cysteine desulfurase (EC 2.8.1.7), SufS subfamily	Thermoanaerobacter tengcongensis MB4 Gene: TTE2670: Cysteine desulfurase (EC 2.8.1.7), SufS subfamily	Caldicellulosiruptor saccharolyticus DSM 8903	Carboxydothermus hydrogenoformans Z-2901	Anaerocellum thermophilum DSM 6725	Moorella thermoacetica ATCC 39073	Cysteine desulfurase (EC 2.8.1.7), SufS subfamily
sufE	Thermoanaerobacter ethanolicus X514 Gene: Teth514_2328: Putative iron-sulfur cluster assembly scaffold protein for SUF system, SufE2	Thermoanaerobacter italicus Ab9 Gene: Thit_2292: Putative iron-sulfur cluster assembly scaffold protein for SUF system, SufE2	Thermoanaerobacter tengcongensis MB4 Gene: TTE2669: Putative iron-sulfur cluster assembly scaffold protein for SUF system, SufE2	Caldicellulosiruptor saccharolyticus DSM 8903	Carboxydothermus hydrogenoformans Z-2901	Anaerocellum thermophilum DSM 6725	Moorella thermoacetica ATCC 39073	Putative iron-sulfur cluster assembly scaffold protein for SUF system, SufE2

CRON 7.
feoA1	* Thermoanaerobacter ethanolicus X514 Site: position = -35 score = 6.45426 sequence = ATTGATAATTATTTTCAAT Gene: Teth514_0187: Ferrous iron transport protein A	* Thermoanaerobacter italicus Ab9 Site: position = -35 score = 6.45426 sequence = ATTGATAATTATTTTCAAT Gene: Thit_0206: Ferrous iron transport protein A	* Thermoanaerobacter tengcongensis MB4 Site: position = -33 score = 6.12052 sequence = ATTGATAATGATTTTCACT Gene: TTE0242: Ferrous iron transport protein A	Caldicellulosiruptor saccharolyticus DSM 8903	Carboxydothermus hydrogenoformans Z-2901	Anaerocellum thermophilum DSM 6725	Moorella thermoacetica ATCC 39073	Ferrous iron transport protein A
feoB1	Thermoanaerobacter ethanolicus X514 Gene: Teth514_0188: Ferrous iron transport protein B	Thermoanaerobacter italicus Ab9 Gene: Thit_0207: Ferrous iron transport protein B	Thermoanaerobacter tengcongensis MB4 Gene: TTE0243: Ferrous iron transport protein B	Caldicellulosiruptor saccharolyticus DSM 8903	Carboxydothermus hydrogenoformans Z-2901	Anaerocellum thermophilum DSM 6725	Moorella thermoacetica ATCC 39073	Ferrous iron transport protein B

CRON 8.
feoA	Thermoanaerobacter ethanolicus X514	Thermoanaerobacter italicus Ab9	Thermoanaerobacter tengcongensis MB4	* Caldicellulosiruptor saccharolyticus DSM 8903 Site: position = -98 score = 6.16578 sequence = ATTGAGAATAATTCTCAAT Gene: Csac_1739: Ferrous iron transport protein A	Carboxydothermus hydrogenoformans Z-2901	* Anaerocellum thermophilum DSM 6725 Site: position = -96 score = 6.59302 sequence = ATTGAAAATGATTTTCAAT Gene: Athe_1564: Ferrous iron transport protein A	* Moorella thermoacetica ATCC 39073 Site: position = -233 score = 6.11892 sequence = ATTGATAATGTTTATCAAT Site: position = -277 score = 5.54422 sequence = ATTGACATTGATTATCATT Gene: Moth_1183: Ferrous iron transport protein A	Ferrous iron transport protein A
feoB	Thermoanaerobacter ethanolicus X514	Thermoanaerobacter italicus Ab9	Thermoanaerobacter tengcongensis MB4	Caldicellulosiruptor saccharolyticus DSM 8903 Gene: Csac_1740: Ferrous iron transport protein B	Carboxydothermus hydrogenoformans Z-2901	Anaerocellum thermophilum DSM 6725 Gene: Athe_1563: Ferrous iron transport protein B	Moorella thermoacetica ATCC 39073 Gene: Moth_1182: Ferrous iron transport protein B	Ferrous iron transport protein B

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog Fur - Thermoanaerobacterales

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --