Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulog TPP - Thermoanaerobacterales

Properties
Regulator type: RNA regulatory element
Name: TPP
RFAM: RF00059
Regulation mode:
Biological process: Thiamine biosynthesis
Effector: Thiamine pyrophosphate
Phylum: Firmicutes
Member of regulog collections
Statistics of regulated genes
Genome Genes Operons
Thermoanaerobacter ethanolicus X514 8 3
Anaerocellum thermophilum DSM 6725 6 1
Thermoanaerobacter italicus Ab9 4 3
Carboxydothermus hydrogenoformans Z-2901 8 3
Caldicellulosiruptor saccharolyticus DSM 8903 7 1
Moorella thermoacetica ATCC 39073 4 3
Thermoanaerobacter tengcongensis MB4 6 3
Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes Function
 
CRON 1.
thiT
*
Thermoanaerobacter ethanolicus X514

Site:
position = -164
score = 78.89
sequence = ATGTCCGCTGGGGGA...

Gene: Teth514_0633: Substrate-specific component ThiT of thiamin ECF transporter
 
Anaerocellum thermophilum DSM 6725

Gene: Athe_0037: Substrate-specific component ThiT of thiamin ECF transporter
*
Thermoanaerobacter italicus Ab9

Site:
position = -166
score = 80.04
sequence = TTATGTCCGCTGGGG...

Gene: Thit_2199: Substrate-specific component ThiT of thiamin ECF transporter
*
Carboxydothermus hydrogenoformans Z-2901

Site:
position = -177
score = 90.86
sequence = ACGGCCACTGGGGGT...

Gene: CHY_0230: Substrate-specific component ThiT of thiamin ECF transporter
 
Caldicellulosiruptor saccharolyticus DSM 8903

Gene: Csac_2579: Substrate-specific component ThiT of thiamin ECF transporter
 
Moorella thermoacetica ATCC 39073
*
Thermoanaerobacter tengcongensis MB4

Site:
position = -168
score = 75.99
sequence = TTATGTCCGCTGGGG...

Gene: TTE2512: Substrate-specific component ThiT of thiamin ECF transporter
Substrate-specific component ThiT of thiamin ECF transporter
 
CRON 2.
thiE
 
Thermoanaerobacter ethanolicus X514
 
Anaerocellum thermophilum DSM 6725
 
Thermoanaerobacter italicus Ab9
 
Carboxydothermus hydrogenoformans Z-2901
 
Caldicellulosiruptor saccharolyticus DSM 8903
*
Moorella thermoacetica ATCC 39073

Site:
position = -202
score = 26.12
sequence = TTAAACCGGAGGGGC...

Gene: Moth_0547: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)
 
Thermoanaerobacter tengcongensis MB4
Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)
 
CRON 3.
thiS
 
Thermoanaerobacter ethanolicus X514
*
Anaerocellum thermophilum DSM 6725

Site:
position = -259
score = 57.04
sequence = TGGTTTTAAGGGGGA...

Gene: Athe_0368: Sulfur carrier protein ThiS
 
Thermoanaerobacter italicus Ab9
 
Carboxydothermus hydrogenoformans Z-2901
*
Caldicellulosiruptor saccharolyticus DSM 8903

Site:
position = -296
score = 61.88
sequence = TGGTTTTAAGGGGGA...

Gene: Csac_0250: Sulfur carrier protein ThiS
 
Moorella thermoacetica ATCC 39073
 
Thermoanaerobacter tengcongensis MB4
Sulfur carrier protein ThiS
thiG
 
Thermoanaerobacter ethanolicus X514
 
Anaerocellum thermophilum DSM 6725

Gene: Athe_0369: Thiazole biosynthesis protein ThiG
 
Thermoanaerobacter italicus Ab9
*
Carboxydothermus hydrogenoformans Z-2901

Site:
position = -468
score = 63.76
sequence = ATATGGTTTAGGGGA...

Gene: CHY_1262: Thiazole biosynthesis protein ThiG
 
Caldicellulosiruptor saccharolyticus DSM 8903

Gene: Csac_0251: Thiazole biosynthesis protein ThiG
*
Moorella thermoacetica ATCC 39073

Site:
position = -376
score = 70.37
sequence = AACATAAGCAGGGGT...

Gene: Moth_1663: Thiazole biosynthesis protein ThiG
 
Thermoanaerobacter tengcongensis MB4
Thiazole biosynthesis protein ThiG
thiH
 
Thermoanaerobacter ethanolicus X514
 
Anaerocellum thermophilum DSM 6725

Gene: Athe_0370: 2-iminoacetate synthase (EC 1.3.99.n2)
 
Thermoanaerobacter italicus Ab9
 
Carboxydothermus hydrogenoformans Z-2901

Gene: CHY_1263: 2-iminoacetate synthase (EC 1.3.99.n2)
 
Caldicellulosiruptor saccharolyticus DSM 8903

Gene: Csac_0252: 2-iminoacetate synthase (EC 1.3.99.n2)
 
Moorella thermoacetica ATCC 39073

Gene: Moth_1664: 2-iminoacetate synthase (EC 1.3.99.n2)
 
Thermoanaerobacter tengcongensis MB4
2-iminoacetate synthase (EC 1.3.99.n2)
thiF
 
Thermoanaerobacter ethanolicus X514

Gene: Teth514_1158: Sulfur carrier protein adenylyltransferase ThiF
 
Anaerocellum thermophilum DSM 6725

Gene: Athe_0371: Sulfur carrier protein adenylyltransferase ThiF
 
Thermoanaerobacter italicus Ab9

Gene: Thit_0463: Sulfur carrier protein adenylyltransferase ThiF
 
Carboxydothermus hydrogenoformans Z-2901

Gene: CHY_1264: Sulfur carrier protein adenylyltransferase ThiF
 
Caldicellulosiruptor saccharolyticus DSM 8903

Gene: Csac_0253: Sulfur carrier protein adenylyltransferase ThiF
 
Moorella thermoacetica ATCC 39073
 
Thermoanaerobacter tengcongensis MB4

Gene: TTE2471: Sulfur carrier protein adenylyltransferase ThiF
Sulfur carrier protein adenylyltransferase ThiF
thiE
 
Thermoanaerobacter ethanolicus X514

Gene: ThiE: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)
 
Anaerocellum thermophilum DSM 6725

Gene: Athe_0372: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)
 
Thermoanaerobacter italicus Ab9

Gene: Thit_0601: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)
*
Carboxydothermus hydrogenoformans Z-2901

Site:
position = -105
score = 75.96
sequence = AAAAACCTCAGGGGT...

Gene: ThiE: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)
 
Caldicellulosiruptor saccharolyticus DSM 8903

Gene: Csac_0254: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)
 
Moorella thermoacetica ATCC 39073
 
Thermoanaerobacter tengcongensis MB4

Gene: TTE2233: Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)
Thiamin-phosphate pyrophosphorylase (EC 2.5.1.3)
thiC
*
Thermoanaerobacter ethanolicus X514

Site:
position = -154
score = 80.87
sequence = TATTTGCCACATGGG...

Gene: Teth514_0974: Thiamin biosynthesis protein ThiC
 
Anaerocellum thermophilum DSM 6725

Gene: Athe_0373: Thiamin biosynthesis protein ThiC
*
Thermoanaerobacter italicus Ab9

Site:
position = -152
score = 81.85
sequence = TTTGCCACATGGGGT...

Gene: Thit_1845: Thiamin biosynthesis protein ThiC
 
Carboxydothermus hydrogenoformans Z-2901

Gene: CHY_0747: Thiamin biosynthesis protein ThiC
 
Caldicellulosiruptor saccharolyticus DSM 8903

Gene: Csac_0255: Thiamin biosynthesis protein ThiC
*
Moorella thermoacetica ATCC 39073

Site:
position = -164
score = 75.47
sequence = AGTTACCCCGGGGGT...

Gene: Moth_1401: Thiamin biosynthesis protein ThiC
*
Thermoanaerobacter tengcongensis MB4

Site:
position = -172
score = 85.0
sequence = ACTCAAGTGCTAGGG...

Gene: TTE1565: Thiamin biosynthesis protein ThiC
Thiamin biosynthesis protein ThiC
thiD
*
Thermoanaerobacter ethanolicus X514

Site:
position = -159
score = 82.64
sequence = ACAAGTGCTAGGGGA...

Gene: ThiD: Phosphomethylpyrimidine kinase (EC 2.7.4.7)
 
Anaerocellum thermophilum DSM 6725

Gene: ThiD: Phosphomethylpyrimidine kinase (EC 2.7.4.7)
*
Thermoanaerobacter italicus Ab9

Site:
position = -158
score = 86.17
sequence = ACAAATGCTAGGGGA...

Gene: ThiD: Phosphomethylpyrimidine kinase (EC 2.7.4.7)
 
Carboxydothermus hydrogenoformans Z-2901
 
Caldicellulosiruptor saccharolyticus DSM 8903

Gene: ThiD: Phosphomethylpyrimidine kinase (EC 2.7.4.7)
 
Moorella thermoacetica ATCC 39073
*
Thermoanaerobacter tengcongensis MB4

Site:
position = -163
score = 85.51
sequence = ATCAAAGTGCTAGGG...

Gene: TTE2235: Phosphomethylpyrimidine kinase (EC 2.7.4.7)
Phosphomethylpyrimidine kinase (EC 2.7.4.7)
thiM
 2
Thermoanaerobacter ethanolicus X514

Gene: Teth514_0567: Hydroxyethylthiazole kinase (EC 2.7.1.50)

Gene: Teth514_0570: Hydroxyethylthiazole kinase (EC 2.7.1.50)
 
Anaerocellum thermophilum DSM 6725
 2
Thermoanaerobacter italicus Ab9

Gene: Thit_0604: Hydroxyethylthiazole kinase (EC 2.7.1.50)

Gene: Thit_0606: Hydroxyethylthiazole kinase (EC 2.7.1.50)
 
Carboxydothermus hydrogenoformans Z-2901

Gene: CHY_0748: Hydroxyethylthiazole kinase (EC 2.7.1.50)
 
Caldicellulosiruptor saccharolyticus DSM 8903
 
Moorella thermoacetica ATCC 39073

Gene: Moth_2017: Hydroxyethylthiazole kinase (EC 2.7.1.50)
 
Thermoanaerobacter tengcongensis MB4

Gene: TTE2232: Hydroxyethylthiazole kinase (EC 2.7.1.50)
Hydroxyethylthiazole kinase (EC 2.7.1.50)
thiW
 
Thermoanaerobacter ethanolicus X514

Gene: Teth514_0568: Substrate-specific component ThiW of predicted thiazole ECF transporter
 
Anaerocellum thermophilum DSM 6725
 
Thermoanaerobacter italicus Ab9

Gene: Thit_0605: Substrate-specific component ThiW of predicted thiazole ECF transporter
 
Carboxydothermus hydrogenoformans Z-2901
 
Caldicellulosiruptor saccharolyticus DSM 8903
 
Moorella thermoacetica ATCC 39073
 
Thermoanaerobacter tengcongensis MB4

Gene: TTE1731: Substrate-specific component ThiW of predicted thiazole ECF transporter
Substrate-specific component ThiW of predicted thiazole ECF transporter
cytX
 
Thermoanaerobacter ethanolicus X514

Gene: Teth514_0569: Predicted hydroxymethylpyrimidine transporter CytX
 
Anaerocellum thermophilum DSM 6725
 
Thermoanaerobacter italicus Ab9
 
Carboxydothermus hydrogenoformans Z-2901
 
Caldicellulosiruptor saccharolyticus DSM 8903
 
Moorella thermoacetica ATCC 39073
 
Thermoanaerobacter tengcongensis MB4

Gene: TTE1730: Predicted hydroxymethylpyrimidine transporter CytX
Predicted hydroxymethylpyrimidine transporter CytX
oarX
 
Thermoanaerobacter ethanolicus X514
 
Anaerocellum thermophilum DSM 6725
 
Thermoanaerobacter italicus Ab9
 
Carboxydothermus hydrogenoformans Z-2901
 
Caldicellulosiruptor saccharolyticus DSM 8903
 
Moorella thermoacetica ATCC 39073
 
Thermoanaerobacter tengcongensis MB4

Gene: TTE2234: Thiamin-related 3-oxoacyl-[acyl-carrier protein] reductase OarX
Thiamin-related 3-oxoacyl-[acyl-carrier protein] reductase OarX
thiL
 
Thermoanaerobacter ethanolicus X514
 
Anaerocellum thermophilum DSM 6725
 
Thermoanaerobacter italicus Ab9
 
Carboxydothermus hydrogenoformans Z-2901

Gene: CHY_0749: Thiamine-monophosphate kinase (EC 2.7.4.16)
 
Caldicellulosiruptor saccharolyticus DSM 8903
 
Moorella thermoacetica ATCC 39073

Gene: Moth_1157: Thiamine-monophosphate kinase (EC 2.7.4.16)
 
Thermoanaerobacter tengcongensis MB4
Thiamine-monophosphate kinase (EC 2.7.4.16)
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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