Regulog BirA - Thermoanaerobacterales

Properties
Regulator type:	Transcription factor
Regulator family:	BirA
Regulation mode:	repressor
Biological process:	Biotin biosynthesis
Effector:	Biotin
Phylum:	Firmicutes
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 11 sites [see more]

Member of regulog collections

By trascription factor - BirA
By taxonomy - Thermoanaerobacterales
By TF family - BirA
By effector - Biotin
By pathway - Biotin biosynthesis

Statistics of regulated genes
Genome	Genes	Operons
Anaerocellum thermophilum DSM 6725	5	3
Caldicellulosiruptor saccharolyticus DSM 8903	5	3
Carboxydothermus hydrogenoformans Z-2901	2	2
Moorella thermoacetica ATCC 39073
Thermoanaerobacter ethanolicus X514	1	1
Thermoanaerobacter italicus Ab9	1	1
Thermoanaerobacter tengcongensis MB4	1	1

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes								Function

CRON 1.
bioY3	* Anaerocellum thermophilum DSM 6725 Site: position = -103 score = 8.46559 sequence = TAGTAAAC-(16)-GTTGACAA Gene: Athe_2544: Substrate-specific component BioY of biotin ECF transporter	* Caldicellulosiruptor saccharolyticus DSM 8903 Site: position = -73 score = 7.60273 sequence = TAGTAAAC-(16)-GTTGACAT Gene: Csac_0304: Substrate-specific component BioY of biotin ECF transporter	Carboxydothermus hydrogenoformans Z-2901	Moorella thermoacetica ATCC 39073	Thermoanaerobacter ethanolicus X514	Thermoanaerobacter italicus Ab9	Thermoanaerobacter tengcongensis MB4	Substrate-specific component BioY of biotin ECF transporter
bioD	Anaerocellum thermophilum DSM 6725 Gene: Athe_2543: Dethiobiotin synthetase (EC 6.3.3.3)	Caldicellulosiruptor saccharolyticus DSM 8903 Gene: Csac_0305: Dethiobiotin synthetase (EC 6.3.3.3)	Carboxydothermus hydrogenoformans Z-2901	Moorella thermoacetica ATCC 39073	Thermoanaerobacter ethanolicus X514	Thermoanaerobacter italicus Ab9	Thermoanaerobacter tengcongensis MB4	Dethiobiotin synthetase (EC 6.3.3.3)
bioA	Anaerocellum thermophilum DSM 6725 Gene: Athe_2542: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)	Caldicellulosiruptor saccharolyticus DSM 8903 Gene: Csac_0306: Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)	Carboxydothermus hydrogenoformans Z-2901	Moorella thermoacetica ATCC 39073	Thermoanaerobacter ethanolicus X514	Thermoanaerobacter italicus Ab9	Thermoanaerobacter tengcongensis MB4	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC 2.6.1.62)

CRON 2.
bioB	* Anaerocellum thermophilum DSM 6725 Site: position = -88 score = 7.619 sequence = ATGTAAAC-(16)-GTTTACTA Gene: Athe_2541: Biotin synthase (EC 2.8.1.6)	* Caldicellulosiruptor saccharolyticus DSM 8903 Site: position = -102 score = 6.34227 sequence = CAGTAAAT-(16)-GTTTACTA Gene: Csac_0307: Biotin synthase (EC 2.8.1.6)	* Carboxydothermus hydrogenoformans Z-2901 Site: position = -83 score = 8.95224 sequence = TTGTTAAC-(15)-GTTGACAA Gene: CHY_0889: Biotin synthase (EC 2.8.1.6)	Moorella thermoacetica ATCC 39073	Thermoanaerobacter ethanolicus X514	Thermoanaerobacter italicus Ab9	Thermoanaerobacter tengcongensis MB4	Biotin synthase (EC 2.8.1.6)

CRON 3.
bioY2	* Anaerocellum thermophilum DSM 6725 Site: position = -47 score = 7.619 sequence = TAGTAAAC-(15)-GTTTACAT Gene: Athe_2725: Substrate-specific component BioY of biotin ECF transporter	* Caldicellulosiruptor saccharolyticus DSM 8903 Site: position = -48 score = 7.03665 sequence = TAGTAAAC-(16)-GTTTACTT Gene: Csac_0198: Substrate-specific component BioY of biotin ECF transporter	* Carboxydothermus hydrogenoformans Z-2901 Site: position = -15 score = 7.23314 sequence = AGGTTAAC-(15)-GTTGACAA Gene: CHY_1642: Substrate-specific component BioY of biotin ECF transporter	Moorella thermoacetica ATCC 39073	Thermoanaerobacter ethanolicus X514	Thermoanaerobacter italicus Ab9	Thermoanaerobacter tengcongensis MB4	Substrate-specific component BioY of biotin ECF transporter

CRON 4.
bioY1	Anaerocellum thermophilum DSM 6725	Caldicellulosiruptor saccharolyticus DSM 8903	Carboxydothermus hydrogenoformans Z-2901	Moorella thermoacetica ATCC 39073 Gene: Moth_0144: Substrate-specific component BioY of biotin ECF transporter	* Thermoanaerobacter ethanolicus X514 Site: position = -86 score = 8.95224 sequence = TTGTTAAC-(15)-GTTGACAA Gene: Teth514_2213: Substrate-specific component BioY of biotin ECF transporter	* Thermoanaerobacter italicus Ab9 Site: position = -86 score = 8.95224 sequence = TTGTTAAC-(15)-GTTGACAA Gene: Thit_0733: Substrate-specific component BioY of biotin ECF transporter	* Thermoanaerobacter tengcongensis MB4 Site: position = -88 score = 8.36989 sequence = TAGTTAAC-(15)-GTTGACAA Gene: TTE0777: Substrate-specific component BioY of biotin ECF transporter	Substrate-specific component BioY of biotin ECF transporter

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

Export
	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog BirA - Thermoanaerobacterales

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --