Collection of regulogs in Deinococcus-Thermus taxonomic group
Genomes | 5 |
TF regulogs | 10 |
TF regulons | 29 |
TF binding sites | 83 |
RNA regulogs | 13 |
RNA regulons | 44 |
RNA sites | 64 |
This collection involves all regulons that were tentatively predicted by applying integrative comparative genomic approach to a single taxonomic group of closely-related genomes. To infer the regulons operated by transcription factors (TFs), we combined the identification of TF binding sites and cross-genome comparison of regulons with the analysis of the genomic and functional context of candidate target genes. To infer the regulons operated by regulatory RNAs such as riboswitches, we identified candidate RNA regulatory elements using HMM profiles and further analyzed their genomic and functional context.
TF | RNA | Total | ||||
---|---|---|---|---|---|---|
Genomes | Regulons | Sites | Regulons | Sites | Regulons | Sites |
Deinococcus deserti VCD115 | 6 | 19 | 11 | 17 | 17 | 36 |
Deinococcus geothermalis DSM 11300 | 6 | 20 | 8 | 11 | 14 | 31 |
Deinococcus radiodurans R1 | 5 | 20 | 8 | 11 | 13 | 31 |
Thermus aquaticus Y51MC23 | 5 | 10 | 9 | 13 | 14 | 23 |
Thermus thermophilus HB27 | 7 | 14 | 8 | 12 | 15 | 26 |
Family | Type | Regulator | Function | |||||
---|---|---|---|---|---|---|---|---|
ArgR | TF | ArgR |
2
ArgR
Deinococcus geothermalis DSM 11300 |
3
ArgR
Deinococcus deserti VCD115 |
2
ArgR
Deinococcus radiodurans R1 |
3
ArgR
Thermus aquaticus Y51MC23 |
3
ArgR
Thermus thermophilus HB27 |
Arginine biosynthesis |
BirA | TF | BirA |
1
BirA
Thermus aquaticus Y51MC23 |
2
BirA
Thermus thermophilus HB27 |
Biotin biosynthesis | |||
GntR/MocR | TF | PdxR2 |
1
PdxR2
Deinococcus deserti VCD115 |
Pyridoxine/pyridoxal homeostasis | ||||
HrcA | TF | HrcA |
2
HrcA
Thermus aquaticus Y51MC23 |
2
HrcA
Thermus thermophilus HB27 |
Heat shock response | |||
LacI | TF | BglR |
2
BglR
Deinococcus geothermalis DSM 11300 |
1
BglR
Deinococcus deserti VCD115 |
1
BglR
Thermus thermophilus HB27 |
Beta-glucosides utilization | ||
TF | DR2501 |
3
DR2501
Deinococcus geothermalis DSM 11300 |
2
DR2501
Deinococcus deserti VCD115 |
3
DR2501
Deinococcus radiodurans R1 |
Sugar utilization | |||
NrdR | TF | NrdR |
1
NrdR
Deinococcus geothermalis DSM 11300 |
2
NrdR
Deinococcus radiodurans R1 |
2
NrdR
Thermus thermophilus HB27 |
Deoxyribonucleotide biosynthesis | ||
Rex | TF | Rex |
3
Rex
Deinococcus geothermalis DSM 11300 |
3
Rex
Deinococcus deserti VCD115 |
2
Rex
Deinococcus radiodurans R1 |
1
Rex
Thermus aquaticus Y51MC23 |
1
Rex
Thermus thermophilus HB27 |
Energy metabolism |
TetR | TF | PaaR |
2
PaaR
Thermus aquaticus Y51MC23 |
2
PaaR
Thermus thermophilus HB27 |
Phenylacetic acid degradation | |||
TF | PaaR2 |
8
PaaR2
Deinococcus geothermalis DSM 11300 |
8
PaaR2
Deinococcus deserti VCD115 |
10
PaaR2
Deinococcus radiodurans R1 |
Phenylacetic acid degradation | |||
RF00050 | RNA | FMN |
1
FMN
Deinococcus geothermalis DSM 11300 |
1
FMN
Deinococcus deserti VCD115 |
1
FMN
Deinococcus radiodurans R1 |
1
FMN
Thermus aquaticus Y51MC23 |
1
FMN
Thermus thermophilus HB27 |
Riboflavin biosynthesis |
RF00059 | RNA | TPP |
2
TPP
Deinococcus geothermalis DSM 11300 |
2
TPP
Deinococcus deserti VCD115 |
2
TPP
Deinococcus radiodurans R1 |
2
TPP
Thermus aquaticus Y51MC23 |
2
TPP
Thermus thermophilus HB27 |
Thiamine biosynthesis |
RF00080 | RNA | yybP-ykoY |
1
yybP-ykoY
Deinococcus deserti VCD115 |
2
yybP-ykoY
Thermus aquaticus Y51MC23 |
2
yybP-ykoY
Thermus thermophilus HB27 |
|||
RF00162 | RNA | SAM |
2
SAM
Deinococcus geothermalis DSM 11300 |
3
SAM
Deinococcus deserti VCD115 |
2
SAM
Deinococcus radiodurans R1 |
1
SAM
Thermus aquaticus Y51MC23 |
1
SAM
Thermus thermophilus HB27 |
Methionine biosynthesis |
RF00174 | RNA | Cobalamin |
2
Cobalamin
Deinococcus geothermalis DSM 11300 |
2
Cobalamin
Deinococcus deserti VCD115 |
2
Cobalamin
Deinococcus radiodurans R1 |
3
Cobalamin
Thermus aquaticus Y51MC23 |
3
Cobalamin
Thermus thermophilus HB27 |
Cobalamin biosynthesis |
RF00230 | RNA | T-box(Gly) |
1
T-box(Gly)
Deinococcus geothermalis DSM 11300 |
1
T-box(Gly)
Deinococcus deserti VCD115 |
1
T-box(Gly)
Deinococcus radiodurans R1 |
Amino acid metabolism | ||
RNA | T-box(Ile) |
1
T-box(Ile)
Deinococcus geothermalis DSM 11300 |
1
T-box(Ile)
Deinococcus deserti VCD115 |
1
T-box(Ile)
Deinococcus radiodurans R1 |
1
T-box(Ile)
Thermus aquaticus Y51MC23 |
1
T-box(Ile)
Thermus thermophilus HB27 |
Amino acid metabolism | |
RNA | T-box(Val) |
1
T-box(Val)
Deinococcus deserti VCD115 |
1
T-box(Val)
Deinococcus radiodurans R1 |
Amino acid metabolism | ||||
RF00234 | RNA | glmS |
1
glmS
Deinococcus geothermalis DSM 11300 |
1
glmS
Deinococcus deserti VCD115 |
1
glmS
Deinococcus radiodurans R1 |
Amino sugar metabolism | ||
RF00515 | RNA | PyrR |
1
PyrR
Thermus aquaticus Y51MC23 |
1
PyrR
Thermus thermophilus HB27 |
Pyrimidine metabolism | |||
RF00557 | RNA | L10_leader |
1
L10_leader
Deinococcus geothermalis DSM 11300 |
1
L10_leader
Deinococcus deserti VCD115 |
1
L10_leader
Thermus aquaticus Y51MC23 |
1
L10_leader
Thermus thermophilus HB27 |
Ribosome biogenesis | |
RF01051 | RNA | GEMM_RNA_motif |
3
GEMM_RNA_motif
Deinococcus deserti VCD115 |
Second messenger response | ||||
RF01055 | RNA | MOCO_RNA_motif |
1
MOCO_RNA_motif
Thermus aquaticus Y51MC23 |
Molybdopterin biosynthesis; Molybdenum homeostasis |