Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of Cobalamin in Thermus thermophilus HB27

Properties
Regulator type: RNA regulatory element
Name: Cobalamin
RFAM: RF00174
Regulation mode:
Biological process: Cobalamin biosynthesis
Effector: Adenosylcobalamin
Regulog: Cobalamin - Deinococcus-Thermus
Under regulation:
- Genes 24
- Operons 3
Member of regulog collections
Regulated operons
Locus Tag Name Function
Position: -209
Score: 45.9
Sequence: AGGGGGAAGACCGGT...
Locus tag: TTP0007
Name: hoxN
Funciton: HoxN/HupN/NixA family cobalt transporter
Locus tag: TTP0008
Name: cbiD
Funciton: Cobalt-precorrin-6 synthase, anaerobic
Locus tag: TTP0009
Name: cbiC
Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
Locus tag: TTP0010
Name: cbiET
Funciton: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
Locus tag: TTP0011
Name: cbiL
Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Locus tag: TTP0012
Name: cbiF
Funciton: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
Locus tag: TTP0013
Name: cbiH
Funciton: Cobalt-precorrin-3b C17-methyltransferase
Locus tag: TTP0014
Name: cbiG
Funciton: Cobalamin biosynthesis protein CbiG
Locus tag: TTP0015
Name: cbiX
Funciton: Sirohydrochlorin cobaltochelatase (EC 4.99.1.3)
Locus tag: TTP0016
Name: DUF3209
Funciton: Hypothetical protein implicated in coenzyme B12 biosynthesis
Locus tag: TTP0017
Name: cobA
Funciton: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)
Locus tag: TTP0018
Name: bluB
Funciton: Cob(II)yrinic acid a,c-diamide reductase
Locus tag: TTP0019
Name: cbiB
Funciton: Adenosylcobinamide-phosphate synthase (EC 6.3.1.10)
Locus tag: TTP0020
Name: TTP0020
Funciton: HEPN domain-containing nucleotidyltransferase
Locus tag: TTP0021
Name: TTP0021
Funciton: Nucleotidyltransferase
Locus tag: TTP0022
Name: cobD
Funciton: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
Locus tag: TTP0023
Name: cbiP-cobU
Funciton: Cobyric acid synthase / Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
TTP0007
hoxN
HoxN/HupN/NixA family cobalt transporter
TTP0008
cbiD
Cobalt-precorrin-6 synthase, anaerobic
TTP0009
cbiC
Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
TTP0010
cbiET
Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
TTP0011
cbiL
Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
TTP0012
cbiF
Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
TTP0013
cbiH
Cobalt-precorrin-3b C17-methyltransferase
TTP0014
cbiG
Cobalamin biosynthesis protein CbiG
TTP0015
cbiX
Sirohydrochlorin cobaltochelatase (EC 4.99.1.3)
TTP0016
DUF3209
Hypothetical protein implicated in coenzyme B12 biosynthesis
TTP0017
cobA
Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)
TTP0018
bluB
Cob(II)yrinic acid a,c-diamide reductase
TTP0019
cbiB
Adenosylcobinamide-phosphate synthase (EC 6.3.1.10)
TTP0020
TTP0020
HEPN domain-containing nucleotidyltransferase
TTP0021
TTP0021
Nucleotidyltransferase
TTP0022
cobD
L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81)
TTP0023
cbiP-cobU
Cobyric acid synthase / Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62)
Position: -240
Score: 35.6
Sequence: GGAAGTCCGGTGAAA...
Locus tag: TTP0160
Name: achX
Funciton: Acyl-CoA hydrolase (EC 3.1.2.20)
Locus tag: TTP0161
Name: nrdB
Funciton: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)
Locus tag: TTP0162
Name: nrdA
Funciton: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)
TTP0160
achX
Acyl-CoA hydrolase (EC 3.1.2.20)
TTP0161
nrdB
Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)
TTP0162
nrdA
Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)
Position: -291
Score: 60.5
Sequence: CCAGGTCCCGTAGCC...
Locus tag: TTC0390
Name: btuF
Funciton: Vitamin B12 ABC transporter, B12-binding component BtuF
Locus tag: TTC0391
Name: btuC
Funciton: Vitamin B12 ABC transporter, permease component
Locus tag: TTC0392
Name: btuD
Funciton: Vitamin B12 ABC transporter, ATP-binding component
Locus tag: TTC0393
Name: COG3411
Funciton: Thioredoxin domain protein
TTC0390
btuF
Vitamin B12 ABC transporter, B12-binding component BtuF
TTC0391
btuC
Vitamin B12 ABC transporter, permease component
TTC0392
btuD
Vitamin B12 ABC transporter, ATP-binding component
TTC0393
COG3411
Thioredoxin domain protein
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