Regulog Cobalamin - Deinococcus-Thermus
| Regulator type: | RNA regulatory element |
| Name: | Cobalamin |
| RFAM: | RF00174 |
| Regulation mode: | |
| Biological process: | Cobalamin biosynthesis |
| Effector: | Adenosylcobalamin |
| Phylum: | Deinococcus-Thermus |
Member of regulog collections
- By taxonomy - Deinococcus-Thermus
- By RNA motif - Cobalamin
- By effector - Adenosylcobalamin
- By pathway - Cobalamin biosynthesis
| Genome | Genes | Operons |
|---|---|---|
| Deinococcus radiodurans R1 | 10 | 2 |
| Deinococcus geothermalis DSM 11300 | 24 | 2 |
| Deinococcus deserti VCD115 | 20 | 2 |
| Thermus thermophilus HB27 | 24 | 3 |
| Thermus aquaticus Y51MC23 | 18 | 3 |
| Genes | Function | |||||
|---|---|---|---|---|---|---|
| CRON 1. | ||||||
| btuF |
*
Deinococcus radiodurans R1 Site: position = -84 score = 17.62 sequence = GGGAAAGTCCGGTTT... Gene: DR2588: Vitamin B12 ABC transporter, B12-binding component BtuF |
*
Deinococcus geothermalis DSM 11300 Site: position = -244 score = 21.57 sequence = GGGAAAGACCGGTGA... Gene: Dgeo_0025: Vitamin B12 ABC transporter, B12-binding component BtuF |
*
Deinococcus deserti VCD115 Site: position = -274 score = 25.48 sequence = GGAAGCAGGTGAAGA... Gene: Deide_02140: Vitamin B12 ABC transporter, B12-binding component BtuF |
*
Thermus thermophilus HB27 Site: position = -291 score = 60.52 sequence = CCAGGTCCCGTAGCC... Gene: TTC0390: Vitamin B12 ABC transporter, B12-binding component BtuF |
*
Thermus aquaticus Y51MC23 Site: position = -291 score = 55.74 sequence = CAGGTCCCGTTTGCC... Gene: TaqDRAFT_5534: Vitamin B12 ABC transporter, B12-binding component BtuF |
Vitamin B12 ABC transporter, B12-binding component BtuF |
| btuC |
Gene: DR2589: Vitamin B12 ABC transporter, permease component |
Gene: Dgeo_0024: Vitamin B12 ABC transporter, permease component |
Gene: Deide_02150: Vitamin B12 ABC transporter, permease component |
Gene: TTC0391: Vitamin B12 ABC transporter, permease component |
Gene: TaqDRAFT_5535: Vitamin B12 ABC transporter, permease component |
Vitamin B12 ABC transporter, permease component |
| btuD |
Gene: DR2590: Vitamin B12 ABC transporter, ATP-binding component |
Gene: Dgeo_0023: Vitamin B12 ABC transporter, ATP-binding component |
Gene: Deide_02160: Vitamin B12 ABC transporter, ATP-binding component |
Gene: TTC0392: Vitamin B12 ABC transporter, ATP-binding component |
Gene: TaqDRAFT_5536: Vitamin B12 ABC transporter, ATP-binding component |
Vitamin B12 ABC transporter, ATP-binding component |
| COG3411 |
Gene: DR2591: Thioredoxin domain protein |
Gene: Dgeo_0022: Thioredoxin domain protein |
Gene: Deide_02170: Thioredoxin domain protein |
Gene: TTC0393: Thioredoxin domain protein |
Gene: TaqDRAFT_5537: Thioredoxin domain protein |
Thioredoxin domain protein |
| CRON 2. | ||||||
| achX |
Gene: DRB0106: Acyl-CoA hydrolase (EC 3.1.2.20) |
Gene: Dgeo_1772: Acyl-CoA hydrolase (EC 3.1.2.20) |
|
*
Thermus thermophilus HB27 Site: position = -240 score = 35.57 sequence = GGAAGTCCGGTGAAA... Gene: TTP0160: Acyl-CoA hydrolase (EC 3.1.2.20) |
*
Thermus aquaticus Y51MC23 Site: position = -260 score = 37.4 sequence = GGAAGTCCGGTGCAA... Gene: TaqDRAFT_3194: Acyl-CoA hydrolase (EC 3.1.2.20) |
Acyl-CoA hydrolase (EC 3.1.2.20) |
| nrdB |
|
|
|
Gene: TTP0161: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1) |
Gene: TaqDRAFT_3195: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1) |
Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1) |
| nrdA |
|
|
|
Gene: TTP0162: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1) |
Gene: TaqDRAFT_3196: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1) |
Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1) |
| CRON 3. | ||||||
| btuF |
*
Deinococcus radiodurans R1 Site: position = -100 score = 13.78 sequence = GGGGAAGCCCGGTGA... Gene: DRB0007: Vitamin B12 ABC transporter, B12-binding component BtuF |
*
Deinococcus geothermalis DSM 11300 Site: position = -259 score = 35.03 sequence = CCGGCTTCTGCTATC... Gene: Dgeo_2363: Vitamin B12 ABC transporter, B12-binding component BtuF |
*
Deinococcus deserti VCD115 Site: position = -242 score = 41.15 sequence = GGAAGTCCGGTGAGA... Gene: Deide_2p01550: Vitamin B12 ABC transporter, B12-binding component BtuF |
|
|
Vitamin B12 ABC transporter, B12-binding component BtuF |
| btuR |
Gene: DRB0008: Cob(I)alamin adenosyltransferase (EC 2.5.1.17) |
Gene: Dgeo_2362: Cob(I)alamin adenosyltransferase (EC 2.5.1.17) |
Gene: Deide_2p01560: Cob(I)alamin adenosyltransferase (EC 2.5.1.17) |
Gene: TTP0002: Cob(I)alamin adenosyltransferase (EC 2.5.1.17) |
Gene: TaqDRAFT_3284: Cob(I)alamin adenosyltransferase (EC 2.5.1.17) |
Cob(I)alamin adenosyltransferase (EC 2.5.1.17) |
| cbiE |
|
Gene: Dgeo_2361: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) |
Gene: Deide_2p01570: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) |
|
|
Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) |
| cbiXC |
|
Gene: Dgeo_2360: Sirohydrochlorin cobaltochelatase (EC 4.99.1.3) / Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) |
Gene: Deide_2p01580: Sirohydrochlorin cobaltochelatase (EC 4.99.1.3) / Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) |
|
|
Sirohydrochlorin cobaltochelatase (EC 4.99.1.3) / Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) |
| cbiD |
|
Gene: Dgeo_2359: Cobalt-precorrin-6 synthase, anaerobic |
Gene: Deide_2p01590: Cobalt-precorrin-6 synthase, anaerobic |
Gene: TTP0008: Cobalt-precorrin-6 synthase, anaerobic |
Gene: TaqDRAFT_5284: Cobalt-precorrin-6 synthase, anaerobic |
Cobalt-precorrin-6 synthase, anaerobic |
| cbiL |
|
Gene: Dgeo_2358: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130) |
Gene: Deide_2p01600: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130) |
Gene: TTP0011: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130) |
Gene: TaqDRAFT_5281: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130) |
Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130) |
| cbiF |
|
Gene: Dgeo_2357: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) |
Gene: Deide_2p01610: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) |
Gene: TTP0012: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) |
Gene: TaqDRAFT_5280: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) |
Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) |
| cbiG |
|
Gene: Dgeo_2356: Cobalamin biosynthesis protein CbiG |
Gene: Deide_2p01620: Cobalamin biosynthesis protein CbiG |
Gene: TTP0014: Cobalamin biosynthesis protein CbiG |
Gene: TaqDRAFT_5278: Cobalamin biosynthesis protein CbiG |
Cobalamin biosynthesis protein CbiG |
| cbiHJ |
|
Gene: Dgeo_2355: Cobalt-precorrin-3b C17-methyltransferase / Cobalt-precorrin-6x reductase (EC 1.3.1.54) |
Gene: Deide_2p01630: Cobalt-precorrin-3b C17-methyltransferase / Cobalt-precorrin-6x reductase (EC 1.3.1.54) |
|
|
Cobalt-precorrin-3b C17-methyltransferase / Cobalt-precorrin-6x reductase (EC 1.3.1.54) |
| cobW |
|
Gene: Dgeo_2354: Cobalamin synthesis protein |
Gene: Deide_2p01640: Cobalamin synthesis protein |
|
|
Cobalamin synthesis protein |
| hoxN |
|
Gene: Dgeo_2353: HoxN/HupN/NixA family cobalt transporter |
Gene: Deide_2p01650: HoxN/HupN/NixA family cobalt transporter |
*
Thermus thermophilus HB27 Site: position = -209 score = 45.89 sequence = AGGGGGAAGACCGGT... Gene: TTP0007: HoxN/HupN/NixA family cobalt transporter |
*
Thermus aquaticus Y51MC23 Site: position = -204 score = 42.11 sequence = AAAGGGGGAAGACCG... Gene: TaqDRAFT_5285: HoxN/HupN/NixA family cobalt transporter |
HoxN/HupN/NixA family cobalt transporter |
| cobN |
|
Gene: Dgeo_2352: Cobaltochelatase, CobN subunit |
Gene: Deide_2p01670: Cobaltochelatase, CobN subunit |
|
|
Cobaltochelatase, CobN subunit |
| Dgeo_2351 |
|
Gene: Dgeo_2351: Methyltransferase type 11 |
|
|
|
Methyltransferase type 11 |
| chlID |
|
Gene: Dgeo_2350: Cobalt chelatase, ChlI subunit / Cobalt chelatase, ChlD subunit |
Gene: Deide_2p01680: Cobalt chelatase, ChlI subunit / Cobalt chelatase, ChlD subunit |
|
|
Cobalt chelatase, ChlI subunit / Cobalt chelatase, ChlD subunit |
| cbiA |
Gene: DRB0009: Cobyrinic acid a,c-diamide synthase |
Gene: Dgeo_2349: Cobyrinic acid a,c-diamide synthase |
Gene: Deide_2p01690: Cobyrinic acid a,c-diamide synthase |
Gene: TTP0001: Cobyrinic acid a,c-diamide synthase |
Gene: TaqDRAFT_3286: Cobyrinic acid a,c-diamide synthase |
Cobyrinic acid a,c-diamide synthase |
| cbiB |
Gene: DRB0010: Adenosylcobinamide-phosphate synthase (EC 6.3.1.10) |
Gene: Dgeo_2348: Adenosylcobinamide-phosphate synthase (EC 6.3.1.10) |
Gene: Deide_2p01700: Adenosylcobinamide-phosphate synthase (EC 6.3.1.10) |
Gene: TTP0019: Adenosylcobinamide-phosphate synthase (EC 6.3.1.10) |
Gene: TaqDRAFT_3278: Adenosylcobinamide-phosphate synthase (EC 6.3.1.10) |
Adenosylcobinamide-phosphate synthase (EC 6.3.1.10) |
| cobD |
Gene: DRB0011: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81) |
Gene: Dgeo_2875: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81) |
|
Gene: TTP0022: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81) |
Gene: TaqDRAFT_3274: L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81) |
L-threonine 3-O-phosphate decarboxylase (EC 4.1.1.81) |
| cbiP |
Gene: DRB0012: Cobyric acid synthase |
Gene: Dgeo_2874: Cobyric acid synthase |
Gene: Deide_2p01820: Cobyric acid synthase |
Gene: TTP0023: Cobyric acid synthase / Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) |
Gene: TaqDRAFT_3272: Cobyric acid synthase / Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) |
Cobyric acid synthase |
| cobU |
Gene: DRA0020: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) |
Gene: Dgeo_2873: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) |
Gene: Deide_2p01830: Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) |
|
|
Adenosylcobinamide-phosphate guanylyltransferase (EC 2.7.7.62) |
| cobT |
Gene: DRA0240: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) |
Gene: Dgeo_2872: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) |
Gene: Deide_2p01840: Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) |
|
|
Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase (EC 2.4.2.21) |
| cbiC |
|
|
|
Gene: TTP0009: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) |
Gene: TaqDRAFT_5283: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) |
Cobalt-precorrin-8x methylmutase (EC 5.4.1.2) |
| cbiET |
|
|
|
Gene: TTP0010: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-) |
Gene: TaqDRAFT_5282: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-) |
Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-) |
| cbiH |
|
|
|
Gene: TTP0013: Cobalt-precorrin-3b C17-methyltransferase |
2
Thermus aquaticus Y51MC23 Gene: TaqDRAFT_5279: Cobalt-precorrin-3b C17-methyltransferase Gene: TaqDRAFT_5224: Cobalt-precorrin-3b C17-methyltransferase |
Cobalt-precorrin-3b C17-methyltransferase |
| cbiX |
|
|
|
Gene: TTP0015: Sirohydrochlorin cobaltochelatase (EC 4.99.1.3) |
Gene: TaqDRAFT_5277: Sirohydrochlorin cobaltochelatase (EC 4.99.1.3) |
Sirohydrochlorin cobaltochelatase (EC 4.99.1.3) |
| DUF3209 |
|
|
|
Gene: TTP0016: Hypothetical protein implicated in coenzyme B12 biosynthesis |
Gene: TaqDRAFT_5276: Hypothetical protein implicated in coenzyme B12 biosynthesis |
Hypothetical protein implicated in coenzyme B12 biosynthesis |
| cobA |
|
|
|
Gene: TTP0017: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) |
Gene: TaqDRAFT_5275: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) |
Uroporphyrinogen-III methyltransferase (EC 2.1.1.107) |
| bluB |
|
|
Gene: Deide_2p01660: Cob(II)yrinic acid a,c-diamide reductase |
Gene: TTP0018: Cob(II)yrinic acid a,c-diamide reductase |
|
Cob(II)yrinic acid a,c-diamide reductase |
| TTP0020 |
|
|
|
Gene: TTP0020: HEPN domain-containing nucleotidyltransferase |
|
HEPN domain-containing nucleotidyltransferase |
| TTP0021 |
|
|
|
Gene: TTP0021: Nucleotidyltransferase |
|
Nucleotidyltransferase |
Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.
Red color - the gene is in non-regulated operon.
Gray color - the orthologous gene is absent.
The star symbol - the TFBS is located in upstream region of this gene.
The number - the numeber of homologs (shown only if it is greater than one).
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Regulated Genes | [ Tab delimited format ] | DOWNLOAD |
|
Regulatory Sites | [ FASTA format ] | DOWNLOAD |