Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of Cobalamin in Thermus aquaticus Y51MC23

Properties
Regulator type: RNA regulatory element
Name: Cobalamin
RFAM: RF00174
Regulation mode:
Biological process: Cobalamin biosynthesis
Effector: Adenosylcobalamin
Regulog: Cobalamin - Deinococcus-Thermus
Under regulation:
- Genes 18
- Operons 3
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -260
Score: 37.4
Sequence: GGAAGTCCGGTGCAA...
Locus tag: TaqDRAFT_3194
Name: achX
Funciton: Acyl-CoA hydrolase (EC 3.1.2.20)
Locus tag: TaqDRAFT_3195
Name: nrdB
Funciton: Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)
Locus tag: TaqDRAFT_3196
Name: nrdA
Funciton: Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)
achX
Acyl-CoA hydrolase (EC 3.1.2.20)
nrdB
Ribonucleotide reductase of class Ia (aerobic), beta subunit (EC 1.17.4.1)
nrdA
Ribonucleotide reductase of class Ia (aerobic), alpha subunit (EC 1.17.4.1)

Position: -204
Score: 42.1
Sequence: AAAGGGGGAAGACCG...
Locus tag: TaqDRAFT_5285
Name: hoxN
Funciton: HoxN/HupN/NixA family cobalt transporter
Locus tag: TaqDRAFT_5284
Name: cbiD
Funciton: Cobalt-precorrin-6 synthase, anaerobic
Locus tag: TaqDRAFT_5283
Name: cbiC
Funciton: Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
Locus tag: TaqDRAFT_5282
Name: cbiET
Funciton: Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
Locus tag: TaqDRAFT_5281
Name: cbiL
Funciton: Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
Locus tag: TaqDRAFT_5280
Name: cbiF
Funciton: Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
Locus tag: TaqDRAFT_5279
Name: cbiH
Funciton: Cobalt-precorrin-3b C17-methyltransferase
Locus tag: TaqDRAFT_5278
Name: cbiG
Funciton: Cobalamin biosynthesis protein CbiG
Locus tag: TaqDRAFT_5277
Name: cbiX
Funciton: Sirohydrochlorin cobaltochelatase (EC 4.99.1.3)
Locus tag: TaqDRAFT_5276
Name: DUF3209
Funciton: Hypothetical protein implicated in coenzyme B12 biosynthesis
Locus tag: TaqDRAFT_5275
Name: cobA
Funciton: Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)
hoxN
HoxN/HupN/NixA family cobalt transporter
cbiD
Cobalt-precorrin-6 synthase, anaerobic
cbiC
Cobalt-precorrin-8x methylmutase (EC 5.4.1.2)
cbiET
Cobalt-precorrin-6y C5-methyltransferase (EC 2.1.1.-) / Cobalt-precorrin-6y C15-methyltransferase [decarboxylating] (EC 2.1.1.-)
cbiL
Cobalt-precorrin-2 C20-methyltransferase (EC 2.1.1.130)
cbiF
Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133)
cbiH
Cobalt-precorrin-3b C17-methyltransferase
cbiG
Cobalamin biosynthesis protein CbiG
cbiX
Sirohydrochlorin cobaltochelatase (EC 4.99.1.3)
DUF3209
Hypothetical protein implicated in coenzyme B12 biosynthesis
cobA
Uroporphyrinogen-III methyltransferase (EC 2.1.1.107)

Position: -291
Score: 55.7
Sequence: CAGGTCCCGTTTGCC...
Locus tag: TaqDRAFT_5534
Name: btuF
Funciton: Vitamin B12 ABC transporter, B12-binding component BtuF
Locus tag: TaqDRAFT_5535
Name: btuC
Funciton: Vitamin B12 ABC transporter, permease component
Locus tag: TaqDRAFT_5536
Name: btuD
Funciton: Vitamin B12 ABC transporter, ATP-binding component
Locus tag: TaqDRAFT_5537
Name: COG3411
Funciton: Thioredoxin domain protein
btuF
Vitamin B12 ABC transporter, B12-binding component BtuF
btuC
Vitamin B12 ABC transporter, permease component
btuD
Vitamin B12 ABC transporter, ATP-binding component
COG3411
Thioredoxin domain protein
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