Collection of regulogs for LiuR transcription factor

Transcription factors LiuR belong to the MerR protein family and control pathways of degradation of branch-chain amino acids (Leu, Ile, Val) in Proteobacteria. The LiuR regulon and its DNA-binding motif were discovered by application of the comparative genomic approach in the Shewanella lineage [21810205]. Then LiuR regulons were reconstructed in other taxonomic groups of Proteobacteria that possess an ortholog of the LiuR regulator [18820024]. In contrast to gamma-, and beta-proteobacteria, where LiuR co-regulates various genes for the Leu-Ile-Val degradation, the reconstructed LiuR regulons in alpha-proteobacteria control a different metabolic pathway, the fatty acid degradation.