Regulog LiuR - Burkholderia

Properties
Regulator type:	Transcription factor
Regulator family:	MerR
Regulation mode:	repressor
Biological process:	Branched-chain amino acid degradation
Effector:
Phylum:	Proteobacteria/beta
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 6 sites [see more]

Member of regulog collections

By trascription factor - LiuR
By taxonomy - Burkholderia
By TF family - MerR
By pathway - Branched-chain amino acid degradation

Statistics of regulated genes
Genome	Genes	Operons
Burkholderia pseudomallei K96243
Burkholderia mallei ATCC 23344
Burkholderia sp. 383
Burkholderia cepacia AMMD
Burkholderia vietnamiensis G4
Burkholderia glumae BGR1
Burkholderia xenovorans LB400	12	3
Burkholderia phymatum STM815	12	3

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes									Function

CRON 1.
liuR	Burkholderia pseudomallei K96243	Burkholderia mallei ATCC 23344	Burkholderia sp. 383	Burkholderia cepacia AMMD	Burkholderia vietnamiensis G4	Burkholderia glumae BGR1	* Burkholderia xenovorans LB400 Site: position = -68 score = 5.99799 sequence = GTTGACGATAACGTAAAC Gene: Bxe_A4252: Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family	* Burkholderia phymatum STM815 Site: position = -101 score = 5.99799 sequence = GTTGACGATAACGTAAAC Gene: Bphy_0181: Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family	Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family
aceK	Burkholderia pseudomallei K96243 Gene: BPSL0373: Isocitrate dehydrogenase phosphatase (EC 2.7.11.5)/kinase (EC 3.1.3.-)	Burkholderia mallei ATCC 23344 Gene: BMA0094: Isocitrate dehydrogenase phosphatase (EC 2.7.11.5)/kinase (EC 3.1.3.-)	Burkholderia sp. 383 Gene: Bcep18194_A6269: Isocitrate dehydrogenase phosphatase (EC 2.7.11.5)/kinase (EC 3.1.3.-)	Burkholderia cepacia AMMD Gene: Bamb_2975: Isocitrate dehydrogenase phosphatase (EC 2.7.11.5)/kinase (EC 3.1.3.-)	Burkholderia vietnamiensis G4 Gene: Bcep1808_3021: Isocitrate dehydrogenase phosphatase (EC 2.7.11.5)/kinase (EC 3.1.3.-)	Burkholderia glumae BGR1 Gene: bglu_1g32370: Isocitrate dehydrogenase phosphatase (EC 2.7.11.5)/kinase (EC 3.1.3.-)	Burkholderia xenovorans LB400 Gene: Bxe_A4253: Isocitrate dehydrogenase phosphatase (EC 2.7.11.5)/kinase (EC 3.1.3.-)	Burkholderia phymatum STM815 Gene: Bphy_0180: Isocitrate dehydrogenase phosphatase (EC 2.7.11.5)/kinase (EC 3.1.3.-)	Isocitrate dehydrogenase phosphatase (EC 2.7.11.5)/kinase (EC 3.1.3.-)
cah	Burkholderia pseudomallei K96243 Gene: BPSL0372: Carbonic anhydrase (EC 4.2.1.1)	Burkholderia mallei ATCC 23344 Gene: BMA0095: Carbonic anhydrase (EC 4.2.1.1)	Burkholderia sp. 383 Gene: Bcep18194_A6270: Carbonic anhydrase (EC 4.2.1.1)	Burkholderia cepacia AMMD Gene: Bamb_2976: Carbonic anhydrase (EC 4.2.1.1)	Burkholderia vietnamiensis G4 Gene: Bcep1808_3022: Carbonic anhydrase (EC 4.2.1.1)	Burkholderia glumae BGR1 Gene: bglu_1g32380: Carbonic anhydrase (EC 4.2.1.1)	Burkholderia xenovorans LB400 Gene: Bxe_A4254: Carbonic anhydrase (EC 4.2.1.1)	Burkholderia phymatum STM815 Gene: Bphy_0179: Carbonic anhydrase (EC 4.2.1.1)	Carbonic anhydrase (EC 4.2.1.1)
ivdA	Burkholderia pseudomallei K96243 Gene: BPSL0371: Acetyl-CoA C-acyltransferase (EC 2.3.1.16)	Burkholderia mallei ATCC 23344 Gene: BMA0096: Acetyl-CoA C-acyltransferase (EC 2.3.1.16)	Burkholderia sp. 383	Burkholderia cepacia AMMD	Burkholderia vietnamiensis G4	Burkholderia glumae BGR1 Gene: bglu_1g32390: Acetyl-CoA C-acyltransferase (EC 2.3.1.16)	Burkholderia xenovorans LB400 Gene: Bxe_A4255: Acetyl-CoA C-acyltransferase (EC 2.3.1.16)	Burkholderia phymatum STM815 Gene: Bphy_0178: Acetyl-CoA C-acyltransferase (EC 2.3.1.16)	Acetyl-CoA C-acyltransferase (EC 2.3.1.16)
Bxe_A4256	Burkholderia pseudomallei K96243 Gene: BPSL0370: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	Burkholderia mallei ATCC 23344 Gene: BMA0097: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	Burkholderia sp. 383 Gene: Bcep18194_A6271: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	Burkholderia cepacia AMMD Gene: Bamb_2977: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	Burkholderia vietnamiensis G4 Gene: Bcep1808_3023: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	Burkholderia glumae BGR1 Gene: bglu_1g32400: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	Burkholderia xenovorans LB400 Gene: Bxe_A4256: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	Burkholderia phymatum STM815 Gene: Bphy_0177: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ivdC	Burkholderia pseudomallei K96243	Burkholderia mallei ATCC 23344	Burkholderia sp. 383	Burkholderia cepacia AMMD	Burkholderia vietnamiensis G4	Burkholderia glumae BGR1	Burkholderia xenovorans LB400 Gene: Bxe_A4257: Isovaleryl-CoA dehydrogenase (EC 1.3.99.10)	Burkholderia phymatum STM815 Gene: Bphy_0176: Isovaleryl-CoA dehydrogenase (EC 1.3.99.10)	Isovaleryl-CoA dehydrogenase (EC 1.3.99.10)
Bxe_A4258	Burkholderia pseudomallei K96243 Gene: BPSL0369: hypothetical protein	Burkholderia mallei ATCC 23344 Gene: BMA0098: hypothetical protein	Burkholderia sp. 383 Gene: Bcep18194_A6272: hypothetical protein	Burkholderia cepacia AMMD Gene: Bamb_2978: hypothetical protein	Burkholderia vietnamiensis G4 Gene: Bcep1808_3024: hypothetical protein	Burkholderia glumae BGR1 Gene: bglu_1g32410: hypothetical protein	Burkholderia xenovorans LB400 Gene: Bxe_A4258: hypothetical protein	Burkholderia phymatum STM815 Gene: Bphy_0175: hypothetical protein	hypothetical protein

CRON 2.
liuA	Burkholderia pseudomallei K96243 Gene: BPSS1448: Isovaleryl-CoA dehydrogenase (EC 1.3.99.10); Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.99.2)	Burkholderia mallei ATCC 23344 Gene: BMAA0802: Isovaleryl-CoA dehydrogenase (EC 1.3.99.10); Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.99.2)	Burkholderia sp. 383 Gene: Bcep18194_B0423: Isovaleryl-CoA dehydrogenase (EC 1.3.99.10); Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.99.2)	Burkholderia cepacia AMMD Gene: Bamb_4588: Isovaleryl-CoA dehydrogenase (EC 1.3.99.10); Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.99.2)	Burkholderia vietnamiensis G4 Gene: Bcep1808_3495: Isovaleryl-CoA dehydrogenase (EC 1.3.99.10); Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.99.2)	Burkholderia glumae BGR1 Gene: bglu_2g11300: Isovaleryl-CoA dehydrogenase (EC 1.3.99.10); Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.99.2)	* Burkholderia xenovorans LB400 Site: position = -163 score = 6.08306 sequence = ATTGACGCTTACGTAAAT Gene: Bxe_B0960: Isovaleryl-CoA dehydrogenase (EC 1.3.99.10); Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.99.2)	* Burkholderia phymatum STM815 Site: position = -187 score = 5.57754 sequence = ATTGACGCATACGTCAAT Gene: Bphy_3562: Isovaleryl-CoA dehydrogenase (EC 1.3.99.10); Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.99.2)	Isovaleryl-CoA dehydrogenase (EC 1.3.99.10); Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.99.2)
liuB	Burkholderia pseudomallei K96243 Gene: BPSS1447: Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4)	Burkholderia mallei ATCC 23344 Gene: BMAA0803: Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4)	Burkholderia sp. 383 Gene: Bcep18194_B0424: Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4)	Burkholderia cepacia AMMD Gene: Bamb_4587: Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4)	Burkholderia vietnamiensis G4 Gene: Bcep1808_3494: Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4)	Burkholderia glumae BGR1 Gene: bglu_2g11290: Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4)	Burkholderia xenovorans LB400 Gene: Bxe_B0961: Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4)	Burkholderia phymatum STM815 Gene: Bphy_3561: Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4)	Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4)
liuC	Burkholderia pseudomallei K96243 Gene: BPSS1446: Methylglutaconyl-CoA hydratase (EC 4.2.1.18)	Burkholderia mallei ATCC 23344 Gene: BMAA0804: Methylglutaconyl-CoA hydratase (EC 4.2.1.18)	Burkholderia sp. 383 Gene: Bcep18194_B0425: Methylglutaconyl-CoA hydratase (EC 4.2.1.18)	Burkholderia cepacia AMMD Gene: Bamb_4586: Methylglutaconyl-CoA hydratase (EC 4.2.1.18)	Burkholderia vietnamiensis G4 Gene: Bcep1808_3493: Methylglutaconyl-CoA hydratase (EC 4.2.1.18)	Burkholderia glumae BGR1 Gene: bglu_2g11280: Methylglutaconyl-CoA hydratase (EC 4.2.1.18)	Burkholderia xenovorans LB400 Gene: Bxe_B0962: Methylglutaconyl-CoA hydratase (EC 4.2.1.18)	Burkholderia phymatum STM815 Gene: Bphy_3560: Methylglutaconyl-CoA hydratase (EC 4.2.1.18)	Methylglutaconyl-CoA hydratase (EC 4.2.1.18)
liuD	Burkholderia pseudomallei K96243 Gene: BPSS1445: Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4)	Burkholderia mallei ATCC 23344 Gene: BMAA0805: Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4)	Burkholderia sp. 383 Gene: Bcep18194_B0426: Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4)	Burkholderia cepacia AMMD Gene: Bamb_4585: Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4)	Burkholderia vietnamiensis G4 Gene: Bcep1808_3492: Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4)	Burkholderia glumae BGR1 Gene: bglu_2g11270: Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4)	Burkholderia xenovorans LB400 Gene: Bxe_B0963: Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4)	Burkholderia phymatum STM815 Gene: Bphy_3559: Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4)	Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4)

CRON 3.
aacS	Burkholderia pseudomallei K96243 Gene: BPSL3394: Acetoacetyl-CoA synthetase [leucine] (EC 6.2.1.16)	Burkholderia mallei ATCC 23344 Gene: BMA2959: Acetoacetyl-CoA synthetase [leucine] (EC 6.2.1.16)	Burkholderia sp. 383 Gene: Bcep18194_A3290: Acetoacetyl-CoA synthetase [leucine] (EC 6.2.1.16)	Burkholderia cepacia AMMD Gene: Bamb_0099: Acetoacetyl-CoA synthetase [leucine] (EC 6.2.1.16)	Burkholderia vietnamiensis G4 Gene: Bcep1808_0117: Acetoacetyl-CoA synthetase [leucine] (EC 6.2.1.16)	Burkholderia glumae BGR1 Gene: bglu_1g00790: Acetoacetyl-CoA synthetase [leucine] (EC 6.2.1.16)	* Burkholderia xenovorans LB400 Site: position = -176 score = 5.38449 sequence = CTTGACGTTTACGGAAAG Gene: Bxe_A0042: Acetoacetyl-CoA synthetase [leucine] (EC 6.2.1.16)	* Burkholderia phymatum STM815 Site: position = -153 score = 5.38449 sequence = CTTGACGTTTACGGAAAG Gene: Bphy_3025: Acetoacetyl-CoA synthetase [leucine] (EC 6.2.1.16)	Acetoacetyl-CoA synthetase [leucine] (EC 6.2.1.16)

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

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	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog LiuR - Burkholderia

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --