Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --

Regulon of LiuR in Burkholderia xenovorans LB400

Properties
Regulator type: Transcription factor
TF locus tag: Bxe_A4252
Regulator family: MerR
Regulation mode: repressor
Biological process: Branched-chain amino acid degradation
Effector:
Regulog: LiuR - Burkholderia
Statistics of regulated genes:
- Genes 12
- Operons 3
Visualization:
Allows to visualize regulon content in the context of metabolic pathways
Built upon 6 sites [see more]
Member of regulog collections
Regulated operons
Locus Tag Name Function

Position: -68
Score: 6
Sequence: GTTGACGATAACGTAAAC
Locus tag: Bxe_A4252
Name: liuR
Funciton: Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family
Locus tag: Bxe_A4253
Name: aceK
Funciton: Isocitrate dehydrogenase phosphatase (EC 2.7.11.5)/kinase (EC 3.1.3.-)
Locus tag: Bxe_A4254
Name: cah
Funciton: Carbonic anhydrase (EC 4.2.1.1)
Locus tag: Bxe_A4255
Name: ivdA
Funciton: Acetyl-CoA C-acyltransferase (EC 2.3.1.16)
Locus tag: Bxe_A4256
Name: null
Funciton: Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Locus tag: Bxe_A4257
Name: ivdC
Funciton: Isovaleryl-CoA dehydrogenase (EC 1.3.99.10)
Locus tag: Bxe_A4258
Name: null
Funciton: hypothetical protein
liuR
Predicted transcriptional regulator LiuR of leucine degradation pathway, MerR family
aceK
Isocitrate dehydrogenase phosphatase (EC 2.7.11.5)/kinase (EC 3.1.3.-)
cah
Carbonic anhydrase (EC 4.2.1.1)
ivdA
Acetyl-CoA C-acyltransferase (EC 2.3.1.16)
Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
ivdC
Isovaleryl-CoA dehydrogenase (EC 1.3.99.10)
hypothetical protein

Position: -163
Score: 6.1
Sequence: ATTGACGCTTACGTAAAT
Locus tag: Bxe_B0960
Name: liuA
Funciton: Isovaleryl-CoA dehydrogenase (EC 1.3.99.10); Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.99.2)
Locus tag: Bxe_B0961
Name: liuB
Funciton: Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4)
Locus tag: Bxe_B0962
Name: liuC
Funciton: Methylglutaconyl-CoA hydratase (EC 4.2.1.18)
Locus tag: Bxe_B0963
Name: liuD
Funciton: Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4)
liuA
Isovaleryl-CoA dehydrogenase (EC 1.3.99.10); Acyl-CoA dehydrogenase, short-chain specific (EC 1.3.99.2)
liuB
Methylcrotonyl-CoA carboxylase carboxyl transferase subunit (EC 6.4.1.4)
liuC
Methylglutaconyl-CoA hydratase (EC 4.2.1.18)
liuD
Methylcrotonyl-CoA carboxylase biotin-containing subunit (EC 6.4.1.4)

Position: -176
Score: 5.4
Sequence: CTTGACGTTTACGGAAAG
Locus tag: Bxe_A0042
Name: aacS
Funciton: Acetoacetyl-CoA synthetase [leucine] (EC 6.2.1.16)
aacS
Acetoacetyl-CoA synthetase [leucine] (EC 6.2.1.16)
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Regulated Genes [ Tab delimited format ] DOWNLOAD
Regulatory Sites [ FASTA format ] DOWNLOAD