Collection of regulogs for IclR transcription factor family

IclR family of transcription factors includes diverse regulators that are involved the control of primary and secondary metabolism, virulence, multidrug resistance, degradation of aromatics, quorum sensing, and sporulation [22382436]. The IclR family comprises regulators acting as repressors, activators and proteins with a dual role [16472303]. IclR-family regulators collectively respond to wide variety of environmental signals, including glyoxylate, pyruvate, 4-nitrotoluene, benzonitrile, glycerol, glucose, 1-hexanol, succinic semialdehyde, allantoin, and many others. IclR-family regulators consist of two characteristic domains, an N-terminal HTH DNA binding domain (PF09339) and a C-terminal effector binding domain (PF01614). more