Regulog GenR - Corynebacteriaceae

Properties
Regulator type:	Transcription factor
Regulator family:	IclR
Regulation mode:	activator (repressor)
Biological process:	3-hydroxybenzoate degradation
Effector:	Gentisate; 3-hydroxybenzoate
Phylum:	Actinobacteria
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 6 sites [see more]

Member of regulog collections

By taxonomy - Corynebacteriaceae
By trascription factor - NagR
By TF family - IclR
By effector - Gentisate
By effector - 3-hydroxybenzoate
By pathway - 3-hydroxybenzoate degradation

Statistics of regulated genes
Genome	Genes	Operons
Corynebacterium amycolatum SK46
Corynebacterium aurimucosum ATCC 700975
Corynebacterium diphtheriae NCTC 13129
Corynebacterium efficiens YS-314	6	3
Corynebacterium glutamicum ATCC 13032	6	3
Corynebacterium jeikeium K411
Corynebacterium kroppenstedtii DSM 44385
Corynebacterium urealyticum DSM 7109

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes									Function

CRON 1.
genR	Corynebacterium amycolatum SK46	Corynebacterium aurimucosum ATCC 700975	Corynebacterium diphtheriae NCTC 13129	* Corynebacterium efficiens YS-314 Site: position = -11 score = 5.61768 sequence = GATTCCTCTATGTGGAAAG Gene: CE2861: 3-hydroxybenzoate degradation transcriptional regulator, IclR family	* Corynebacterium glutamicum ATCC 13032 Site: position = -26 score = 5.39701 sequence = GATTCCGCTATCTGGAAAG Gene: cg3352: 3-hydroxybenzoate degradation transcriptional regulator, IclR family	Corynebacterium jeikeium K411	Corynebacterium kroppenstedtii DSM 44385	Corynebacterium urealyticum DSM 7109	3-hydroxybenzoate degradation transcriptional regulator, IclR family

CRON 2.
genK	Corynebacterium amycolatum SK46	Corynebacterium aurimucosum ATCC 700975	Corynebacterium diphtheriae NCTC 13129	* Corynebacterium efficiens YS-314 Site: position = -57 score = 5.83774 sequence = CTTTCCACATAGAGGAATC Gene: CE2862: Gentisate transporter, MFS family	* Corynebacterium glutamicum ATCC 13032 Site: position = -90 score = 5.68516 sequence = CTTTCCAGATAGCGGAATC Gene: cg3353: Gentisate transporter, MFS family	Corynebacterium jeikeium K411	Corynebacterium kroppenstedtii DSM 44385	Corynebacterium urealyticum DSM 7109	Gentisate transporter, MFS family
genH	Corynebacterium amycolatum SK46	Corynebacterium aurimucosum ATCC 700975	Corynebacterium diphtheriae NCTC 13129	Corynebacterium efficiens YS-314 Gene: CE2863: 3-hydroxybenzoate 6-hydroxylase	Corynebacterium glutamicum ATCC 13032 Gene: cg3354: 3-hydroxybenzoate 6-hydroxylase	Corynebacterium jeikeium K411	Corynebacterium kroppenstedtii DSM 44385	Corynebacterium urealyticum DSM 7109	3-hydroxybenzoate 6-hydroxylase

CRON 3.
genD	Corynebacterium amycolatum SK46	Corynebacterium aurimucosum ATCC 700975	Corynebacterium diphtheriae NCTC 13129	* Corynebacterium efficiens YS-314 Site: position = -102 score = 5.74705 sequence = ATTTCCGCATAGCGGAAAC Gene: CE2860: Gentisate 1,2-dioxygenase (EC 1.13.11.4)	* Corynebacterium glutamicum ATCC 13032 Site: position = -166 score = 6.14157 sequence = GATTCCACATAGCGGAATT Gene: cg3351: Gentisate 1,2-dioxygenase (EC 1.13.11.4)	Corynebacterium jeikeium K411	Corynebacterium kroppenstedtii DSM 44385	Corynebacterium urealyticum DSM 7109	Gentisate 1,2-dioxygenase (EC 1.13.11.4)
genF	Corynebacterium amycolatum SK46	Corynebacterium aurimucosum ATCC 700975	Corynebacterium diphtheriae NCTC 13129	Corynebacterium efficiens YS-314 Gene: CE2859: Fumarylpyruvate hydrolase	Corynebacterium glutamicum ATCC 13032 Gene: cg3350: Fumarylpyruvate hydrolase	Corynebacterium jeikeium K411	Corynebacterium kroppenstedtii DSM 44385	Corynebacterium urealyticum DSM 7109	Fumarylpyruvate hydrolase
genM	Corynebacterium amycolatum SK46	Corynebacterium aurimucosum ATCC 700975	Corynebacterium diphtheriae NCTC 13129	Corynebacterium efficiens YS-314 Gene: CE2858: Maleylpyruvate isomerase, mycothiol-dependent (EC 5.2.1.4)	Corynebacterium glutamicum ATCC 13032 Gene: cg3349: Maleylpyruvate isomerase, mycothiol-dependent (EC 5.2.1.4)	Corynebacterium jeikeium K411	Corynebacterium kroppenstedtii DSM 44385	Corynebacterium urealyticum DSM 7109	Maleylpyruvate isomerase, mycothiol-dependent (EC 5.2.1.4)

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

Export
	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog GenR - Corynebacteriaceae

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --