Regulog MhpR - Chloroflexia

Properties
Regulator type:	Transcription factor
Regulator family:	IclR
Regulation mode:	repressor
Biological process:	Utilization of aromatic compounds
Effector:
Phylum:	Chloroflexi
Visualization:
	Allows to visualize regulog content in the context of metabolic pathways

Built upon 6 sites [see more]

Member of regulog collections

By taxonomy - Chloroflexi
By TF family - IclR
By pathway - Utilization of aromatic compounds

Statistics of regulated genes
Genome	Genes	Operons
Chloroflexus aggregans DSM 9485	12	2
Chloroflexus sp. Y-400-fl	13	2
Roseiflexus castenholzii DSM 13941	11	1
Roseiflexus sp. RS-1	11	1
Herpetosiphon aurantiacus ATCC 23779

Clusters of co-Regulated Orthologous operoNs (CRONs)
Genes						Function

CRON 1.
Cagg_2029	* Chloroflexus aggregans DSM 9485 Site: position = -146 score = 5.75499 sequence = AATTCGGTATAACCGAACG Gene: Cagg_2029: Enoyl-CoA hydratase (EC 4.2.1.17)	* Chloroflexus sp. Y-400-fl Site: position = -110 score = 5.57886 sequence = AATTCGACATAGTCGAACG Gene: Chy400_1468: Enoyl-CoA hydratase (EC 4.2.1.17)	Roseiflexus castenholzii DSM 13941 Gene: Rcas_0914: Enoyl-CoA hydratase (EC 4.2.1.17)	Roseiflexus sp. RS-1 Gene: RoseRS_4259: Enoyl-CoA hydratase (EC 4.2.1.17)	Herpetosiphon aurantiacus ATCC 23779	Enoyl-CoA hydratase (EC 4.2.1.17)

CRON 2.
hpaB	* Chloroflexus aggregans DSM 9485 Site: position = -135 score = 5.75499 sequence = CGTTCGGTTATACCGAATT Gene: Cagg_2030: 4-hydroxyphenylacetate 3-monooxygenase (EC 1.14.13.3)	* Chloroflexus sp. Y-400-fl Site: position = -138 score = 5.57886 sequence = CGTTCGACTATGTCGAATT Gene: Chy400_1469: 4-hydroxyphenylacetate 3-monooxygenase (EC 1.14.13.3)	* Roseiflexus castenholzii DSM 13941 Site: position = -222 score = 5.75499 sequence = CGTTCGGCTATACCGAATA Gene: Rcas_2414: 4-hydroxyphenylacetate 3-monooxygenase (EC 1.14.13.3)	* Roseiflexus sp. RS-1 Site: position = -229 score = 5.75499 sequence = CGTTCGACTATACCGAACA Gene: RoseRS_2569: 4-hydroxyphenylacetate 3-monooxygenase (EC 1.14.13.3)	Herpetosiphon aurantiacus ATCC 23779	4-hydroxyphenylacetate 3-monooxygenase (EC 1.14.13.3)
pheB	Chloroflexus aggregans DSM 9485 Gene: Cagg_2031: Catechol 2,3-dioxygenase (EC 1.13.11.2)	Chloroflexus sp. Y-400-fl Gene: Chy400_1470: Catechol 2,3-dioxygenase (EC 1.13.11.2)	Roseiflexus castenholzii DSM 13941 Gene: Rcas_2413: Catechol 2,3-dioxygenase (EC 1.13.11.2)	Roseiflexus sp. RS-1 Gene: RoseRS_2570: Catechol 2,3-dioxygenase (EC 1.13.11.2)	Herpetosiphon aurantiacus ATCC 23779	Catechol 2,3-dioxygenase (EC 1.13.11.2)
mhpR	Chloroflexus aggregans DSM 9485 Gene: Cagg_2032: Predicted transcriptional regulator of aromatic compound utilization pathway, IclR family	Chloroflexus sp. Y-400-fl Gene: Chy400_1471: Predicted transcriptional regulator of aromatic compound utilization pathway, IclR family	Roseiflexus castenholzii DSM 13941 Gene: Rcas_2412: Predicted transcriptional regulator of aromatic compound utilization pathway, IclR family	Roseiflexus sp. RS-1 Gene: RoseRS_2571: Predicted transcriptional regulator of aromatic compound utilization pathway, IclR family	Herpetosiphon aurantiacus ATCC 23779	Predicted transcriptional regulator of aromatic compound utilization pathway, IclR family
mhpF	Chloroflexus aggregans DSM 9485 Gene: Cagg_2033: Acetaldehyde dehydrogenase, acetylating, (EC 1.2.1.10) in gene cluster for degradation of phenols, cresols, catechol	Chloroflexus sp. Y-400-fl Gene: Chy400_1472: Acetaldehyde dehydrogenase, acetylating, (EC 1.2.1.10) in gene cluster for degradation of phenols, cresols, catechol	Roseiflexus castenholzii DSM 13941 Gene: Rcas_2411: Acetaldehyde dehydrogenase, acetylating, (EC 1.2.1.10) in gene cluster for degradation of phenols, cresols, catechol	Roseiflexus sp. RS-1 Gene: RoseRS_2572: Acetaldehyde dehydrogenase, acetylating, (EC 1.2.1.10) in gene cluster for degradation of phenols, cresols, catechol	Herpetosiphon aurantiacus ATCC 23779	Acetaldehyde dehydrogenase, acetylating, (EC 1.2.1.10) in gene cluster for degradation of phenols, cresols, catechol
leuA	Chloroflexus aggregans DSM 9485 Gene: Cagg_2034: 4-hydroxy-2-oxovalerate aldolase (EC 4.1.3.-)	Chloroflexus sp. Y-400-fl Gene: Chy400_1473: 4-hydroxy-2-oxovalerate aldolase (EC 4.1.3.-)	Roseiflexus castenholzii DSM 13941 Gene: Rcas_2410: 4-hydroxy-2-oxovalerate aldolase (EC 4.1.3.-)	Roseiflexus sp. RS-1 Gene: RoseRS_2573: 4-hydroxy-2-oxovalerate aldolase (EC 4.1.3.-)	Herpetosiphon aurantiacus ATCC 23779	4-hydroxy-2-oxovalerate aldolase (EC 4.1.3.-)
COG1853	Chloroflexus aggregans DSM 9485 Gene: Cagg_2035: flavin reductase domain protein FMN-binding	Chloroflexus sp. Y-400-fl Gene: Chy400_1474: flavin reductase domain protein FMN-binding	Roseiflexus castenholzii DSM 13941 Gene: Rcas_2409: flavin reductase domain protein FMN-binding	Roseiflexus sp. RS-1 Gene: RoseRS_2574: flavin reductase domain protein FMN-binding	Herpetosiphon aurantiacus ATCC 23779	flavin reductase domain protein FMN-binding
Chy400_1475	Chloroflexus aggregans DSM 9485	Chloroflexus sp. Y-400-fl Gene: Chy400_1475: alpha/beta hydrolase fold protein	Roseiflexus castenholzii DSM 13941	Roseiflexus sp. RS-1	Herpetosiphon aurantiacus ATCC 23779	alpha/beta hydrolase fold protein
pptA	Chloroflexus aggregans DSM 9485 Gene: Cagg_2036: 4-oxalocrotonate tautomerase (EC 5.3.2.-)	Chloroflexus sp. Y-400-fl Gene: Chy400_1476: 4-oxalocrotonate tautomerase (EC 5.3.2.-)	Roseiflexus castenholzii DSM 13941 Gene: Rcas_2408: 4-oxalocrotonate tautomerase (EC 5.3.2.-)	Roseiflexus sp. RS-1 Gene: RoseRS_2575: 4-oxalocrotonate tautomerase (EC 5.3.2.-)	Herpetosiphon aurantiacus ATCC 23779	4-oxalocrotonate tautomerase (EC 5.3.2.-)
mhpD	Chloroflexus aggregans DSM 9485 Gene: Cagg_2037: 2-keto-4-pentenoate hydratase (EC 4.2.1.-)	Chloroflexus sp. Y-400-fl Gene: Chy400_1477: 2-keto-4-pentenoate hydratase (EC 4.2.1.-)	Roseiflexus castenholzii DSM 13941 Gene: Rcas_2407: 2-keto-4-pentenoate hydratase (EC 4.2.1.-)	Roseiflexus sp. RS-1 Gene: RoseRS_2576: 2-keto-4-pentenoate hydratase (EC 4.2.1.-)	Herpetosiphon aurantiacus ATCC 23779	2-keto-4-pentenoate hydratase (EC 4.2.1.-)
dmpC	Chloroflexus aggregans DSM 9485 Gene: Cagg_2038: 2-hydroxymuconic semialdehyde dehydrogenase (EC 1.2.1.85)	Chloroflexus sp. Y-400-fl Gene: Chy400_1478: 2-hydroxymuconic semialdehyde dehydrogenase (EC 1.2.1.85)	Roseiflexus castenholzii DSM 13941 Gene: Rcas_2406: 2-hydroxymuconic semialdehyde dehydrogenase (EC 1.2.1.85)	Roseiflexus sp. RS-1 Gene: RoseRS_2577: 2-hydroxymuconic semialdehyde dehydrogenase (EC 1.2.1.85)	Herpetosiphon aurantiacus ATCC 23779	2-hydroxymuconic semialdehyde dehydrogenase (EC 1.2.1.85)
mhpD2	Chloroflexus aggregans DSM 9485 Gene: Cagg_2039: 2-keto-4-pentenoate hydratase (EC 4.2.1.-)	Chloroflexus sp. Y-400-fl Gene: Chy400_1479: 2-keto-4-pentenoate hydratase (EC 4.2.1.-)	Roseiflexus castenholzii DSM 13941 Gene: Rcas_2405: 2-keto-4-pentenoate hydratase (EC 4.2.1.-)	Roseiflexus sp. RS-1 Gene: RoseRS_2578: 2-keto-4-pentenoate hydratase (EC 4.2.1.-)	Herpetosiphon aurantiacus ATCC 23779	2-keto-4-pentenoate hydratase (EC 4.2.1.-)
Cagg_2040	Chloroflexus aggregans DSM 9485 Gene: Cagg_2040: hypothetical protein	Chloroflexus sp. Y-400-fl Gene: Chy400_1480: hypothetical protein	Roseiflexus castenholzii DSM 13941 Gene: Rcas_2404: hypothetical protein	Roseiflexus sp. RS-1 Gene: RoseRS_2579: hypothetical protein	Herpetosiphon aurantiacus ATCC 23779	hypothetical protein

Bluish color - the gene is in regulated operon. Different regulated operons are shown in different shades of blue.

Red color - the gene is in non-regulated operon.

Gray color - the orthologous gene is absent.

The star symbol - the TFBS is located in upstream region of this gene.

The number - the numeber of homologs (shown only if it is greater than one).

Export
	Regulated Genes	[ Tab delimited format ]	DOWNLOAD
	Regulatory Sites	[ FASTA format ]	DOWNLOAD

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes -- version 3.2 --

Regulog MhpR - Chloroflexia

Collection of Manually Curated Inferences of Regulons in Prokaryotic Genomes
-- version 3.2 --